Ascovirus (taxid:43680)

VIRION

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Virions consist of an envelope, a core, and an internal lipid membrane associated with the inner particle. Virion can be bacilliform, ovoidal or allantoid in shape, mesuring about 130 nm in diameter, by 200-400 nm in length. Contains at least 15 different proteins.

GENOME

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Circular, dsDNA genome of 156-186 kb. The genome contains two tandem of inverted repeats.

GENE EXPRESSION

Encode for up to 180 open reading frames.

ENZYMES

REPLICATION

NUCLEUS

  1. Attachment of the viral proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane occurs; and the viral DNA is released into the nucleus.
  3. Transcription of viral genes, replication of the DNA genome in the nucleus.
  4. Cell nucleus enlarges and ruptures.
  5. Assembly of new virions in the cytoplasm.
  6. Host cell is cleaved in cluster of virion-containing vesicles.

Host-virus interaction

Apoptosis modulation

The Spodoptera frugiperda ascovirus encodes a viral caspase that is able to induce apoptosis in insect cells.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

34 entries grouped by protein

3 entries

Major capsid protein

Select_allDeselect_all
CAPSD_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
CAPSD_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
CAPSD_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Executioner caspase (EC 3.4.22.-)

CASP_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

2 entries

Caspase-like protein

Select_allDeselect_all
CSPL_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
CSPL_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

3 entries

DNA polymerase (EC 2.7.7.7)

Select_allDeselect_all
DPOL_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
DPOL_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
DPOL_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

2 entries

Putative esterase (EC 3.1.1.1)

Select_allDeselect_all
ESTE_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
ESTE_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

3 entries

Putative ATP-dependent RNA helicase (EC 3.6.4.13)

Select_allDeselect_all
HELI1_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
HELI1_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
HELI1_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

3 entries

Putative matrix metalloproteinase (EC 3.4.24.-)

Select_allDeselect_all
MMP_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
MMP_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
MMP_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF11

Y011_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Uncharacterized protein ORF12

Y012_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Uncharacterized protein ORF17

Y017_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF18

Y018_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF42

Y042_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

2 entries

Structural protein ORF43

Select_allDeselect_all
Y043_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

Uncharacterized protein ORF43

Y043_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF57

Y057_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF58

Y058_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF59

Y059_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Putative structural protein ORF84

Y084_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Structural protein ORF142

Y142_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Putative structural protein ORF146

Y146_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Structural protein ORF147

Y147_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF148

Y148_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF149

Y149_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF150

Y150_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Spodoptera frugiperda ascovirus 1a taxid:113370

Protein ModelArchive
104.6 Tyrosine protein kinase/Liposaccharide-modifying enzyme ma-jd-viral-12354
11.6 kDa BRO-N-like ma-jd-viral-18763
12.3 kDa BRO-N-like ma-jd-viral-52159
12.4 kDa BRO-like protein ma-jd-viral-18315
12.6 kDa Inhibitor of apoptosis/RING-finger profile ma-jd-viral-23217
13 kDa ma-jd-viral-67368
13 kDa GIY-YIG-like endonuclease ma-jd-viral-16346
13.1 kDa ma-jd-viral-54651
13.7 kDa ma-jd-viral-57067
13.8 kDa ma-jd-viral-37028
14.1 kDa ma-jd-viral-41769
14.4 kDa HMG_Box/Yabby-like ma-jd-viral-53222
15 kDa ma-jd-viral-55873
15.0 kDa ma-jd-viral-06847
15.2 kDa ma-jd-viral-64025
15.7 kDa ma-jd-viral-67057
16 kDa ma-jd-viral-38569
16.2 kDa PutA/Proline dehydrogenase ma-jd-viral-50425
16.3 kDa ma-jd-viral-29319
16.4 kDa RING/U box ma-jd-viral-40305
16.8 kDa Rad50-like protein ma-jd-viral-58212
17 kDa ma-jd-viral-63947
18.2 kDa BRCA1-like protein ma-jd-viral-44287
18.3 kDa ma-jd-viral-24125
18.3 kDa v-ski oncogene-like ma-jd-viral-39264
19 kDa ma-jd-viral-43658
19.3 kDa ma-jd-viral-41157
19.6 kDa Homer-like ma-jd-viral-39266
19.9 kDa GAPDH active site ma-jd-viral-34915
20.3 kDa ma-jd-viral-18294
21.0 kDa GroEL-like chaperone ma-jd-viral-52010
21.1 kDa ma-jd-viral-58353
21.1 kDa Makorin-like, E3 ubiquitin ligase ma-jd-viral-46478
21.8 kD Zn-finger/nucleic acid binding ma-jd-viral-12233
22.2 kDa ma-jd-viral-59794
22.3 kDa ma-jd-viral-51303
22.4 kDa CTD phosphatase ma-jd-viral-06282
22.6 kDa ma-jd-viral-37163
23.7 kDa Zinc finger C2H2 type domain ma-jd-viral-52790
24.2 kDa ma-jd-viral-39651
24.4 kDa ma-jd-viral-31974
24.5 kDa ma-jd-viral-46534
24.7 kDa ma-jd-viral-06834
25 kDa Endoprotease ma-jd-viral-62371
25.4 kDa ma-jd-viral-29573
25.4 kDa ma-jd-viral-41229
25.6 kDa (O48L homologue) ma-jd-viral-45796
25.6 kDa Uvr/REP helicase ma-jd-viral-06114
25.7 Inhibitor of apoptosis/RING/U box ma-jd-viral-34695
26.1 kDa ma-jd-viral-12311
26.2 kDa ma-jd-viral-64828
26.3 kDa RecD exoV/alpha subunit ma-jd-viral-15628
27.1 kDa ma-jd-viral-35756
27.1 kDa ma-jd-viral-59246
27.4 Inhibitor of apoptosis/ RING/U box ma-jd-viral-55728
27.5 kDa ma-jd-viral-53838
28.6 kDa ma-jd-viral-57871
28.7 kDa DNA puffC4B-like protein ma-jd-viral-38709
28.8 kDa ma-jd-viral-52432
28.8 kDa Fatty acid elongase ma-jd-viral-60178
29 kDa ma-jd-viral-35514
29.2 kDa ma-jd-viral-32196
29.3 kDa ma-jd-viral-08355
29.6 kDa S1/P1 nuclease ma-jd-viral-29332
30 kDa ma-jd-viral-57377
30.3 kDa Myristylated membrane protein-like ma-jd-viral-29853
31 kDa ma-jd-viral-32556
31.0 kDa ma-jd-viral-34858
31.3 kDa RNAseIII-like ma-jd-viral-20040
32.2 kDa ma-jd-viral-32443
33 kDa ma-jd-viral-38821
33.9 kDa ma-jd-viral-37390
34.5 kDa Patatin phospholipase ma-jd-viral-03042
35.1 kDa ma-jd-viral-31924
35.6 kDa ma-jd-viral-32946
37 kDa ma-jd-viral-50866
37.3 kDa Putative ligase ma-jd-viral-41537
37.6 kDa ma-jd-viral-38601
37.7 kDa ma-jd-viral-14170
38 kDa ma-jd-viral-32294
38 kDa Toll-like receptor ma-jd-viral-53686
39.8 kDa PlsC phosphate acyltransferase ma-jd-viral-60617
40.2 kDa BRO-like protein (AV1-BRO-17 protein) ma-jd-viral-23632
40.5 kDa ma-jd-viral-42774
40.8 kDa FEN-1/FLAP-like endonuclease XPG N-I domain ma-jd-viral-22507
41.8 Metallo-dependent calcineurin-like phosphatase ma-jd-viral-30586
44.8 kDa ATPase ma-jd-viral-10589
45.4 DNA replication factor ma-jd-viral-16287
47.7 kDa RNAse III ma-jd-viral-52936
50 kDa ma-jd-viral-64406
50 kDa Cathepsin B ma-jd-viral-41148
50.8 kDa Serine/threonine protein kinase ma-jd-viral-50567
52 kDa Protein kinase ma-jd-viral-24971
63.4 kDa Multifunctional domains-SbcC/ATPase, SMC, HEC1, Reovirus-sigma1, and Intermediate filament protein... ma-jd-viral-56971
64.2 kDa Inhibitor of apoptosis/RING-finger profile ma-jd-viral-30619
64.6 kDa ma-jd-viral-35702
65.6 kDa ma-jd-viral-38052
7.3 kDa ma-jd-viral-31846
7.9 kDa ma-jd-viral-55317
70.4 kDa C-terminal Zn-finger DNA-binding domain ma-jd-viral-38050
77.2 kDa ma-jd-viral-48680
78.7 kDa SbcC subunit C ma-jd-viral-62343
8.6 kDa ma-jd-viral-58993
8.6 kDa Lipocalin signature ma-jd-viral-40861
9.3 kDa ma-jd-viral-55589
90 kDa Serine/threonine protein kinase ma-jd-viral-05046
94.9 kDa DNA primase/Poxvirus D5 family ma-jd-viral-17578
DNA polymerase (EC 2.7.7.7) ma-jd-viral-17284
DNA-directed RNA polymerase (EC 2.7.7.6) ma-jd-viral-50342
DNA-directed RNA polymerase (EC 2.7.7.6) ma-jd-viral-45102
DNA-directed RNA polymerase subunit (EC 2.7.7.6) ma-jd-viral-58702
Executioner caspase (EC 3.4.22.-) ma-jd-viral-10958
Major capsid protein ma-jd-viral-17948
Putative ATP-dependent RNA helicase (EC 3.6.4.13) ma-jd-viral-23196
Putative esterase (EC 3.1.1.1) ma-jd-viral-41452
Putative matrix metalloproteinase (EC 3.4.24.-) ma-jd-viral-20045
Putative structural protein ORF84 ma-jd-viral-49723
Sulfhydryl oxidase (EC 1.8.3.2) ma-jd-viral-46862
Thymidine kinase ma-jd-viral-25181
Uncharacterized protein ORF11 ma-jd-viral-35544
Uncharacterized protein ORF12 ma-jd-viral-30397
Uncharacterized protein ORF42 ma-jd-viral-37270
Uncharacterized protein ORF43 ma-jd-viral-02261