Narnavirus

VIRION

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No true virion, no structural proteins. Genomes are associated with their RdRp in the cytoplasm.

GENOME

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Monopartite, linear, ssRNA(+) genome of of 2.5-2.9 kb.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genome has one ORF encoding an RNA-dependent RNA polymerase.

REPLICATION

CYTOPLASMIC

  1. Virus genome is transmitted horizontally through mating or vertically from mother to daughter cells.
  2. Translation of genomic RNA produces viral RdRp.
  3. A dsRNA genome is synthesized from the genomic ssRNA(+).
  4. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.