Viral genome excision

Most temperate phages encode an integrase for both integration and excision. Excision may require an accessory protein called excisionase or recombination directionality factor to promote excision Excision is the recombination event that leads to the release of a viral genome that was formerly integrated into the host DNA chromosome as a provirus. This release is usually induced upon changes in the host cell physiology (induction).


NB. Aberrant excision may occur. Small pieces of bacterial DNA may become excised and packaged into the bacteriophage capsid together with the bacteriophage genome. This exchange of genetic information is called transduction .

Matching UniProtKB/Swiss-Prot entries

17 entries grouped by strain (browse by keywords)

2 entries

Escherichia phage Mu (Bacteriophage Mu) reference strain

Select_allDeselect_all
TERL_BPMU Probable terminase, large subunit gp28 (EC 3.1.-.-) (Gene product 28) (gp28) (Gene product E) (gpE) ...
TERS_BPMU Probable terminase, small subunit gp27 (Gene product 27) (gp27) (Gene product D) (gpD) (Pacase, ...

2 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

Select_allDeselect_all
VXIS_LAMBD Excisionase
VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)

1 entry

Acyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1) reference strain

VXIS_BPAPS Probable excisionase (p40)

1 entry

Mycobacterium phage D29 (Mycobacteriophage D29) reference strain

VXIS_BPMD2 Excisionase (Gp36)

1 entry

Mycobacterium phage L5 (Mycobacteriophage L5) reference strain

VXIS_BPML5 Excisionase (Gene product 36) (Gp36)

1 entry

Salmonella phage HK620 (Bacteriophage HK620) reference strain

VXIS_BPHK6 Probable excisionase hkaC

1 entry

Salmonella phage P22 (Bacteriophage P22) reference strain

VXIS_BPP22 Excisionase

1 entry

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain

VXIS_BPSFV Probable excisionase hkaC

1 entry

Shigella phage SfV (Shigella flexneri bacteriophage V) (Bacteriophage SfV) reference strain

VXIS_BPSF5 Excisionase

1 entry

Streptomyces phage phiC31 (Bacteriophage phi-C31) reference strain

RDF_BPPHC Recombination directionality factor (RDF) (Gene product 3) (gp3)

1 entry

Enterobacteria phage 434 (Bacteriophage 434)

VXIS_BP434 Excisionase

1 entry

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

VXIS_BPP21 Excisionase

1 entry

Enterobacteria phage phi80 (Bacteriophage phi-80)

VXIS_BPPH8 Excisionase

1 entry

Escherichia phage HK022 (Bacteriophage HK022)

VXIS_BPHK0 Excisionase

1 entry

Staphylococcus phage L54a (Bacteriophage L54a)

VXIS_BPL54 Excisionase