Nyamiviridae (taxid:1513294)



Enveloped, spherical. Diameter from 100 to 130 nm.



Negative-stranded RNA linear genome, about 11,6 kb in size. Encodes for six proteins.


The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.




  1. Attachement of the viral GP glycoproteins to host receptors mediates Clathrin-mediated endocytosis of the virus into the host cell
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released and migrates to the nucleus.
  3. Sequential transcription, viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. Neo-synthesized ribo-nucleocapsids exit out of the nucleus by nuclear pore export.
  6. Cytoplasmic ribo-nucleocapsids bind to the matrix protein under cell membrane, inducing particle budding.
  7. Release of new virions.

Host-virus interaction

These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Beihai rhabdo-like virus 4 taxid:1922654

Protein ModelArchive
Capsid protein ma-jd-viral-29165
Putative nucleoprotein ma-jd-viral-01060

Beihai rhabdo-like virus 5 taxid:1922655

Protein ModelArchive
Putative nucleoprotein ma-jd-viral-01061
Uncharacterized protein ma-jd-viral-33228
Uncharacterized protein ma-jd-viral-54530

Beihai rhabdo-like virus 6 taxid:1922656

Protein ModelArchive
Putative glycoprotein ma-jd-viral-48462
Putative nucleoprotein ma-jd-viral-15079
Uncharacterized protein ma-jd-viral-55909

Nyavirus midwayense taxid:644609

Protein ModelArchive
Nucleocapsid ma-jd-viral-15070
ORF III ma-jd-viral-43734
ORF IV ma-jd-viral-41688
Putative glycoprotein ma-jd-viral-59853
Putative phosphoprotein ma-jd-viral-67182

Sierra Nevada virus taxid:1424280

Protein ModelArchive
M protein ma-jd-viral-41689
Nucleocapsid ma-jd-viral-15071
P protein ma-jd-viral-43733
Putative glycoprotein ma-jd-viral-59855
X protein ma-jd-viral-46070

Socyvirus heteroderae taxid:1034377

Protein ModelArchive
Glycoprotein ma-jd-viral-34677
N-protein ma-jd-viral-15313
Uncharacterized protein ma-jd-viral-29536
Uncharacterized protein ma-jd-viral-53420

Wenling crustacean virus 12 taxid:1923481

Protein ModelArchive
Putative nucleoprotein ma-jd-viral-15080
Uncharacterized protein ma-jd-viral-29738

Wenzhou Crab Virus 1 taxid:1608091

Protein ModelArchive
Glycoprotein ma-jd-viral-48463
Nucleocapsid ma-jd-viral-15078

Wenzhou tapeworm virus 1 taxid:1923661

Protein ModelArchive
Nucleoprotein ma-jd-viral-32284
Putative glycoprotein ma-jd-viral-51883
Uncharacterized protein ma-jd-viral-51737
Uncharacterized protein ma-jd-viral-46132