Potyvirus

VIRION

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Non-enveloped, flexuous, filamentous, of 720-850 nm long and 12-15 nm in diameter. Symmetry helical. Presence of characteristic inclusion bodies within infected plant cells.

GENOME

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Monopartite, linear, ssRNA(+) genome of 10 kb in size. 3' terminus has a poly (A) tract. 5' terminus has a genome-linked protein (VPg).

GENE EXPRESSION

Virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA is translated into polyproteins by VPG-EIF4 Viral initiation of translation. The polyproteins are then processed into functional products by the action of three viral-encoded proteinases. P3N-PIPO is expressed by polymerase slippage mechanism from the P3 ORF and probably acts as a movement protein .

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce a polyprotein which is processed by viral proteases into the RdRp protein and structural proteins.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Virus assembly in the cytoplasm.
  7. Viral movement protein P3N-PIPO probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Potyviruses HC-PRO functions as a suppressor of RNA silencing .

Suppression of other plant defenses

VPg is a potent inhibitor of PAP depurination of RNA, thereby suppressing one of the plant defense mechanisms .

Matching UniProtKB/Swiss-Prot entries

49 entries grouped by protein (browse by keywords)

24 entries

P3N-PIPO polyprotein

Select_allDeselect_all
MVP_PVYN
Potato virus Y (strain N) (PVY) reference strain
MVP_BCMNN
Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))
MVP_BTMV
Beet mosaic virus (BtMV)
MVP_BYMV
Bean yellow mosaic virus
MVP_LMV0
Lettuce mosaic virus (strain 0 / isolate French) (LMV)
MVP_LMVE
Lettuce mosaic virus (strain E) (LMV)
MVP_PEMVC
Pepper mottle virus (isolate California) (PeMV) (PepMoV C)
MVP_PEMVM
Peanut mottle virus (strain M)
MVP_PPVD
Plum pox potyvirus (strain D) (PPV)
MVP_PPVNA
Plum pox potyvirus (isolate NAT) (PPV)
MVP_PPVSK
Plum pox potyvirus (strain SK 68) (PPV)
MVP_PRSVH
Papaya ringspot virus (strain P / mutant HA)
MVP_PSBMV
Pea seed-borne mosaic virus (strain DPD1)
MVP_PVMA
Potato virus A (PVA)
MVP_PVYHU
Potato virus Y (strain Hungarian) (PVY)
MVP_SBMVG
Soybean mosaic virus (strain G2) (SMV)
MVP_SBMVN
Soybean mosaic virus (strain N) (SMV)
MVP_TEV
Tobacco etch virus (TEV)
MVP_TUMVJ
Turnip mosaic virus (strain Japanese) (TuMV)
MVP_TUMVQ
Turnip mosaic virus (strain Quebec) (TuMV)
MVP_TVMV
Tobacco vein mottling virus (TVMV)
MVP_ZYMVC
Zucchini yellow mosaic virus (strain California) (ZYMV)
MVP_ZYMVR
Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)
MVP_ZYMVS
Zucchini yellow mosaic virus (strain Singapore) (ZYMV)

25 entries

Genome polyprotein

Select_allDeselect_all
POLG_PVYN
Potato virus Y (strain N) (PVY) reference strain
POLG_BCMNN
Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))
POLG_BTMV
Beet mosaic virus (BtMV)
POLG_BYMV
Bean yellow mosaic virus
POLG_LMV0
Lettuce mosaic virus (strain 0 / isolate French) (LMV)
POLG_LMVE
Lettuce mosaic virus (strain E) (LMV)
POLG_PEMVC
Pepper mottle virus (isolate California) (PeMV) (PepMoV C)
POLG_PEMVM
Peanut mottle virus (strain M)
POLG_PPVD
Plum pox potyvirus (strain D) (PPV)
POLG_PPVNA
Plum pox potyvirus (isolate NAT) (PPV)
POLG_PPVRA
Plum pox potyvirus (strain Rankovic) (PPV)
POLG_PPVSK
Plum pox potyvirus (strain SK 68) (PPV)
POLG_PRSVH
Papaya ringspot virus (strain P / mutant HA)
POLG_PSBMV
Pea seed-borne mosaic virus (strain DPD1)
POLG_PVMA
Potato virus A (PVA)
POLG_PVYHU
Potato virus Y (strain Hungarian) (PVY)
POLG_SBMVG
Soybean mosaic virus (strain G2) (SMV)
POLG_SBMVN
Soybean mosaic virus (strain N) (SMV)
POLG_TEV
Tobacco etch virus (TEV)
POLG_TUMVJ
Turnip mosaic virus (strain Japanese) (TuMV)
POLG_TUMVQ
Turnip mosaic virus (strain Quebec) (TuMV)
POLG_TVMV
Tobacco vein mottling virus (TVMV)
POLG_ZYMVC
Zucchini yellow mosaic virus (strain California) (ZYMV)
POLG_ZYMVR
Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)
POLG_ZYMVS
Zucchini yellow mosaic virus (strain Singapore) (ZYMV)