T5virus

VIRION

Non-enveloped, head-tail structure. The capsid is about 90 nm in diameter, with a T=13 icosahedral symmetry . It is composed of 11 pentamers at the vertices and 120 hexamers on the faces. The tail is about 160 nm in length and 9 nm in width, with a subterminal disk and 3 long kinked fibers (120 nm). There is also a conical tip with a single straight central fiber (50 nm).

GENOME

Linear, dsDNA genome of about 121 kb, containing about 160 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Viral exolysin degrades host cell wall locally.
  3. Ejection by long flexible tail ejection system: viral DNA is injected in host cell cytoplasm.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by DNA strand displacement replication.
  6. Transcription and translation of late genes
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fibers assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

45 entries grouped by strain (browse by keywords)

All proteins are shown (view only 43 complete proteome entries)

43 entries

Escherichia phage T5 (Enterobacteria phage T5) reference strain

Select_allDeselect_all
DNMK_BPT5 Deoxynucleoside-5'-monophosphate kinase (EC 2.7.4.13)
DPOL_BPT5 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)
DIT_BPT5 Distal tail protein (Dit) (Tail protein pb9)
DUT_BPT5 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
EXO5_BPT5 T5 flap endonuclease (T5FEN) (EC 3.1.11.-) (5'-3' exonuclease) (Exodeoxyribonuclease) (EC 3.1.11.3)
EXO1_BPT5 Probable exonuclease subunit 1 (EC 3.1.11.-) (D12)
ENDO1_BPT5 Putative endonuclease (EC 3.1.-.-)
ENLYS_BPT5 L-alanyl-D-glutamate peptidase (EC 3.4.24.-) (Endolysin) (Lysozyme)
ENDO2_BPT5 Putative endonuclease (EC 3.1.-.-)
ENDON_BPT5 Nicking endonuclease (EC 3.1.21.-)
D5_BPT5 Putative transcription factor D5
DMP_BPT5 5'-deoxynucleotidase (EC 3.1.3.89) (Deoxynucleoside-5'-monophosphatase) (5'-dNMPase) (Protein dmp)
DECO_BPT5 Decoration protein (Capsid protein pb10)
D14_BPT5 Protein D14
RBP5_BPT5 Receptor-binding protein (RBP) (Tail protein pb5)
PRO_BPT5 Prohead protease (EC 3.4.21.-)
SSDNA_BPT5 Probable ssDNA-binding protein (Protein D11)
EXO2_BPT5 Probable exonuclease subunit 2 (EC 3.1.11.-) (D13)
HOLIN_BPT5 Holin
HCP_BPT5 Head completion protein (HCP) (p144)
HEL10_BPT5 Probable helicase D10 (EC 3.6.4.-) (Protein D10)
FIBC_BPT5 Probable central straight fiber (Tail protein pb4)
FIBL2_BPT5 L-shaped tail fiber protein p132
FRD_BPT5 Dihydrofolate reductase (EC 1.5.1.3)
FIBL1_BPT5 L-shaped tail fiber protein pb1 (LTF) (EC 3.4.21.-) (Tail protein pb1)
TUBE_BPT5 Tail tube protein (TTP) (Tail protein pb6)
TFLII_BPT5 H-N-H endonuclease F-TflII (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflII) (HNH endonuclease ...
TFLIV_BPT5 H-N-H endonuclease F-TflIV (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflIV) (HNH endonuclease ...
TFLI_BPT5 H-N-H endonuclease F-TflI (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflI) (HNH endonuclease F-TflI)
TERL_BPT5 Terminase, large subunit (EC 3.1.-.-) (DNA-packaging protein)
TAIL1_BPT5 Minor tail protein (Tail protein p140)
THY_BPT5 Probable thymidylate synthase (EC 2.1.1.45)
TMP_BPT5 Probable tape measure protein (Tail protein pb2)
TTTP_BPT5 Tail tube terminator protein (TrP) (Tail protein p142) (Tail-to-head joining protein) (THJP)
LLP_BPT5 Lytic conversion lipoprotein
OBP_BPT5 Putative replication origin binding protein (D2 helicase)
CAPSD_BPT5 Major capsid protein (Capsid protein pb8) (Major head protein) [Cleaved into: Scaffolding domain ...
BPPB3_BPT5 Probable baseplate hub protein (BHP) (Tail protein pb3)
COMPL_BPT5 Tail completion protein (Tail protein p143)
A1_BPT5 Protein A1
A2_BPT5 Protein A2
TERS_BPT5 Probable terminase, small subunit
PORTL_BPT5 Portal protein (Capsid protein pb7)

2 entries

Escherichia phage Bf23 (Enterobacteria phage BF23)

Select_allDeselect_all
Y9KD_BPBF2 Uncharacterized 9.2 kDa protein
A2_BPBF2 Protein A2-A3