Lederbergvirus

VIRION

Non-enveloped, head-tail structure. The capsid is about 60-65 nm in diameter, with a T=7 laevo icosahedral symmetry . The tail is non-contractile, has 6 prominent tail spikes.

GENOME

Linear, dsDNA genome of about 41 kb encoding for at least 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA. Transcription and translation of late genes.
  5. Assembly of an empty procapsid and packaging of the genome.
  6. Viral tail fibers assembly and viral tail assembly.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

74 entries grouped by strain (browse by keywords)

63 entries

Salmonella phage P22 (Bacteriophage P22) reference strain

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PORTL_BPP22 Portal protein (Gene product 1) (Gp1) (Head-to-tail connector)
GP20_BPP22 Internal virion protein gp20 (Ejection protein gp20) (E protein gp20)
CAPSD_BPP22 Major capsid protein (Gene product 5) (gp5) (Major head protein)
GP7_BPP22 Internal virion protein gp7 (Ejection protein gp7) (E protein gp7)
EXLYS_BPP22 Peptidoglycan hydrolase gp4 (Gene product 4) (Gp4) (Internal virion protein gp4) (Tail adapter ...
ENLYS_BPP22 Endolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)
NINE_BPP22 Protein ninE
NINX_BPP22 Putative protein ninX
NINY_BPP22 Putative protein ninY
RANT_BPP22 Antirepressor protein ant
RARC_BPP22 Transcriptional repressor arc
NIND_BPP22 Protein ninD
RCRO_BPP22 Regulatory protein cro (Antirepressor)
RAL_BPP22 Restriction inhibitor protein ral (Antirestriction protein)
FIBER_BPP22 Tail spike protein (TSP) (Endo-1,3-alpha-L-rhamnosidase) (EC 3.2.1.-) (Endorhamnosidase) (Gene ...
SIEA_BPP22 Superinfection exclusion protein A
SIEB_BPP22 Superinfection exclusion protein B
NEEDL_BPP22 Tail needle protein gp26 (Head completion protein) (Packaged DNA stabilization protein) (Tail ...
TERL_BPP22 Terminase, large subunit (DNA-packaging protein gp2) [Includes: Endonuclease (EC 3.1.21.-); ATPase ...
NINF_BPP22 Protein ninF
NING_BPP22 Protein ninG
NINH_BPP22 Protein ninH
HOLIN_BPP22 Antiholin (Lysis inhibitor 13-108)
NINB_BPP22 Protein ninB
REGN_BPP22 Probable regulatory protein N
VINT_BPP22 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
SPAN1_BPP22 Spanin, inner membrane subunit (i-spanin) (Gene product 15) (Gp15) (Lysis protein Rz)
REGQ_BPP22 Antitermination protein Q
VG18_BPP22 DNA replication protein gp18
VG17_BPP22 Superinfection exclusion protein (Protein gp17)
VEAI_BPP22 Eai protein
VEAG_BPP22 Eag protein
VEAE_BPP22 Eae protein
Y9K0_BPP22 Uncharacterized 9.0 kDa protein in gp15-gp3 intergenic region (ORF80)
VG08_BPP22 Scaffolding protein (Protein gp8)
Y23K_BPP22 Uncharacterized 22.8 kDa protein in gp15-gp3 intergenic region (ORF201)
Y6K4_BPP22 Uncharacterized 6.4 kDa protein in sieA-mnt intergenic region (ORF59A)
YO48_BPP22 Uncharacterized 5.8 kDa protein (ORF48)
SPAN2_BPP22 Probable spanin, outer lipoprotein subunit (o-spanin) (Rz1 protein)
RPC2_BPP22 Repressor protein C2
RPC3_BPP22 Regulatory protein C3 (CIII)
VG10_BPP22 Packaged DNA stabilization protein gp10
Y6K6_BPP22 Uncharacterized 6.6 kDa protein in eae-abc2 intergenic region (ORF56)
Y7K8_BPP22 Uncharacterized 7.8 kDa protein in ral-gp17 intergenic region (ORF67)
VG12_BPP22 Replicative DNA helicase (EC 3.6.4.12) (Replication protein gp12)
Y8K6_BPP22 Uncharacterized 8.6 kDa protein in ral-gp17 intergenic region (ORF78)
VXIS_BPP22 Excisionase
VEAA_BPP22 Eaa protein
VEAC_BPP22 Eac protein
VKIL_BPP22 Protein kil
VEAF_BPP22 Eaf protein
Y7K7_BPP22 Uncharacterized 7.7 kDa protein in gp5-gp4 intergenic region (ORF 109) (ORF69)
ERF_BPP22 Essential recombination function protein
GTRA_BPP22 Bactoprenol-linked glucose translocase
GTRB_BPP22 Bactoprenol glucosyl transferase (EC 2.4.1.-)
ABC1_BPP22 Anti-RecBCD protein 1 (Protein abc1)
ABC2_BPP22 Anti-RecBCD protein 2 (Protein abc2)
EAD_BPP22 Ead protein
TERS_BPP22 Terminase, small subunit (DNA-packaging protein gp3)
RMNT_BPP22 Regulatory protein mnt
RPC1_BPP22 Transcriptional activator protein C1
VARF_BPP22 Accessory recombination function protein
GP16_BPP22 Internal virion protein gp16 (Ejection protein gp16) (E protein gp16)

1 entry

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain

VXIS_BPSFV Probable excisionase hkaC

2 entries

Enterobacteria phage HK620 (Bacteriophage HK620) reference strain

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VG07_BPHK6 DNA transfer protein gp7
VXIS_BPHK6 Probable excisionase hkaC

2 entries

Salmonella phage ST64T (Bacteriophage ST64T) reference strain

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VG07_BPST6 DNA transfer protein gp7
DECO_BPST6 Decoration protein (Dec)

2 entries

Salmonella phage P22 (Bacteriophage P22)

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Y55K_BPP22 Uncharacterized 55.3 kDa protein in gtrB 5'region (ORF485)
VG14_BPP22 Protein gp14

3 entries

Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)

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FIBER_BPSFV Tail spike protein (TSP) (Endo-1,3-alpha-L-rhamnosidase) (EC 3.2.1.-) (Endorhamnosidase)
OAC_BPSFV O-acetyl transferase (EC 2.3.1.-) (O-antigen acetylase)
VINT_BPSFV Integrase (EC 2.7.7.-) (EC 3.1.-.-)

1 entry

Enterobacteria phage LP7 (Bacteriophage LP7)

TERS_BPLP7 Terminase, small subunit (DNA-packaging protein gp3)