Lederbergvirus

VIRION

Non-enveloped, head-tail structure. The capsid is about 60-65 nm in diameter, with a T=7 laevo icosahedral symmetry . The tail is non-contractile, has 6 prominent tail spikes.

GENOME

Linear, dsDNA genome of about 41 kb encoding for at least 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA. Transcription and translation of late genes.
  5. Assembly of an empty procapsid and packaging of the genome.
  6. Viral tail fibers assembly and viral tail assembly.
  7. Mature virions are released from the cell by lysis.