Chlorovirus (taxid:181083)
VIRION
Enveloped virion of which the membrane is surrounded by a capsid with an icosahedral symmetry (T=169), 100-220 nm in diameter. Dense material are present at each 5-fold symmetry vertex
Source: Van Etten 2003 (Pubmed)
GENOME
Linear, dsDNA genome of about 330 kb with crosslinked hairpin ends. PBCV-1 genome encode for approximately 700 ORFs.
GENE EXPRESSION
ENZYMES
- DNA-directed DNA polymerase B [F8TTZ2] [P30321]
- Cell-type capping
- Endonuclease [P31117]
- HNH nuclease [Q84584] [Q84668] [Q98474]
- DNA ligase [O41026]
- Exonuclease [Q84486]
- Helicase [Q84473] [Q84561] [Q98507] [O41030]
- Ribonucleoside-diphosphate reductase
- Thymidylate synthase [O41156]
- Deoxyuridine 5'-triphosphate nucleotidohydrolase [O41033]
- Deoxynucleoside kinase [Q98468]
- CMP/dCMP-type deaminase [O41078] [Q84520]
- UDP-glucose 6-dehydrogenase [O41091]
- RNAse [Q98514]
- tRNA(Ile)-lysidine synthetase [O41036]
- Protease (Peptidase S33) [Q84588]
- Protease Q84668
- Aspartate carbamoyltransferase [Q84489]
- Glutamine amidotransferase [Q84421]
- Arginine/Ornithine decarboxylase [Q84527]
- Protein kinase [O41099] [O41096] [Q84595] [Q89369] [Q84599] [Q89566] [Q84605] [Q84594]
- Protein phosphatase [Q84621]
- Superoxide dismutase [Q90023]
- Sulfhydryl oxidase [Q98515] [Q98523]
- Glycosyltransferase [Q84542] [O41028]
- D-lactate dehydrogenase [Q89388]
REPLICATION
NUCLEO-CYTOPLASMIC
- Virus attaches to host receptors , inducing release of viral genome into the cell.
- Migration of the DNA core to the nucleus?
- Synthesis of early proteins.
- Replication of genomic DNA..
- Late proteins synthesis, assembly of new virions in the cytoplasm
- Cell lysis and virion release in the extracellular space.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)40 entries grouped by protein
1 entry
Putative protein A464R
1 entry
Putative transposase A625R
2 entries
DNA polymerase (EC 2.7.7.7)
1 entry
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
1 entry
Exolysin (EC 4.2.2.-)
1 entry
Potassium channel protein kcv
1 entry
mRNA-capping enzyme (GTP--RNA guanylyltransferase) (mRNA guanylyltransferase) (EC 2.7.7.50)
1 entry
Major capsid protein (MCP) (Vp54)
2 entries
Type II methyltransferase M.CviBI (M.CviBI) (EC 2.1.1.72) (Adenine-specific methyltransferase CviBI) (Modification methylase CviBI)
1 entry
Type II methyltransferase M.CviAII (M.CviAII) (EC 2.1.1.72) (Adenine-specific methyltransferase CviAII) (Modification methylase CviAII)
1 entry
Modification methylase CviBIII (M.CviBIII) (EC 2.1.1.72) (Adenine-specific methyltransferase CviBIII) (Orphan methyltransferase M.CviBIII)
1 entry
Type II methyltransferase M.CvrRI (M.CviRI) (EC 2.1.1.72) (Adenine-specific methyltransferase CviRI) (Modification methylase CviRI)
1 entry
Minor capsid protein P10
1 entry
Minor capsid protein P11
1 entry
Minor capsid protein P12
1 entry
Minor capsid protein P13
1 entry
Minor capsid protein P14
1 entry
Minor capsid protein P2
1 entry
Minor capsid protein 3 (Minor capsid protein Vp20.5)
1 entry
Minor capsid protein P4
1 entry
Minor capsid protein P5
1 entry
Minor capsid protein P6 (Minor capsid protein Vp25)
1 entry
Minor capsid protein P7
1 entry
Minor capsid protein P8
1 entry
Minor capsid protein P9
1 entry
Probable DNA polymerase sliding clamp 1 (Proliferating cell nuclear antigen homolog 1) (PCNA 1)
1 entry
Probable DNA polymerase sliding clamp 2 (Proliferating cell nuclear antigen homolog 2) (PCNA 2)
1 entry
Penton capsid protein P1
1 entry
Superoxide dismutase
1 entry
Type II restriction enzyme CviJI (R.CviJI) (EC 3.1.21.4) (Endonuclease CviJI) (Type-2 restriction enzyme CviJI)
1 entry
Type II restriction enzyme CviAII (R.CviAII) (EC 3.1.21.4) (Endonuclease CviAII) (Type-2 restriction enzyme CviAII)
1 entry
Probable flavin-dependent thymidylate synthase (FDTS) (EC 2.1.1.148) (FAD-dependent thymidylate synthase)
1 entry
5'RNA triphosphatase A449R (EC 3.6.1.74)
1 entry
Viral polyamine acetyltransferase (vPAT) (EC 2.3.1.57)
1 entry
Uncharacterized protein A284L
1 entry
Putative ABC transporter A445L
1 entry
Putative transcription factor A494R
1 entry