Nucleorhabdovirus

VIRION

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Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.

GENOME

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Negative-stranded RNA linear genome, about 11-15 kb in size. Encodes for 5 to six proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

REPLICATION

IN PLANT:NUCLEAR

  1. Virus penetrates into the cell by effraction or plasmodesmata transport.
  2. Viral nucleocapsid is transported into the host nucleus
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid can penetrate in neighboring plant cells through plasmodesmata transport
  6. Alternatively the ribonucleocapsid can binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

IN INSECT:NUCLEAR

  1. Attachment of the viral G glycoproteins to host receptors.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Viral nucleocapsid is transported into the host nucleus
  4. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  5. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  6. The ribonucleocapsid binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

Host-virus interaction

Movement through plasmodesmata

Viral movement protein 3of RYSV presumably interacts with host plasmodesmata to allow tubule guided movement of viral genomic material from cell to cell without budding.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by protein (browse by keywords)

4 entries

Glycoprotein

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GLYCO_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain
GLYCO_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
GLYCO_SYNV
Sonchus yellow net virus (SYNV) reference strain

Spike glycoprotein

GLYCO_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

4 entries

RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase)

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L_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain
L_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
L_SYNV
Sonchus yellow net virus (SYNV) reference strain
L_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

4 entries

Matrix protein

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MATRX_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain
MATRX_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
MATRX_SYNV
Sonchus yellow net virus (SYNV) reference strain

Matrix protein (M2 protein)

MATRX_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

4 entries

Movement protein (MP) (Cell-to-cell transport protein) (Protein 3)

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MVP_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain

Putative movement protein 3 (MP) (Cell-to-cell transport protein) (Protein 3)

MVP_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
MVP_SYNV
Sonchus yellow net virus (SYNV) reference strain

Movement protein (MP) (Cell-to-cell transport protein) (Protein Sc4)

MVP_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

4 entries

Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)

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NCAP_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain
NCAP_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
NCAP_SYNV
Sonchus yellow net virus (SYNV) reference strain
NCAP_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

4 entries

Phosphoprotein (Protein P) (Protein M1)

Select_allDeselect_all
PHOSP_MMVR
Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain
PHOSP_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain
PHOSP_SYNV
Sonchus yellow net virus (SYNV) reference strain
PHOSP_TAVCV
Taro vein chlorosis virus (TAVCV) reference strain

1 entry

Protein 6

VP6_RYSV
Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain