SARS coronavirus 2 (SARS-CoV-2) proteome

This page provides pre-release access to the SARS Coronavirus 2 protein sequences in UniProt from the current public health emergency. The data will become part of a future UniProt release and may be subject to further changes.

COVID-19 UniProt resource PDB structures

Swissmodel 3d
Annotated UniProtKB protein entries:notes
P0DTC1 Replicase polyprotein 1a (pp1a) Viral transcription/replication
P0DTD1 Replicase polyprotein 1ab (pp1ab) Viral transcription/replication, ribosomal frameshift
P0DTC2 Spike glycoprotein (S) Attachment and entry
P0DTC3 Protein 3a (NS3a) ESCRT-independent budding
P0DTC4 Envelope small membrane protein (E) ESCRT-independent budding
P0DTC5 Membrane protein (M) Virion morphegenesis
P0DTC6 Non-structural protein 6 (NS6) Unknown, host-virus modulation?
P0DTC7 Protein 7a (NS7a) Unknown, host-virus modulation?
P0DTD8 Protein 7b (NS7b) Unknown, host-virus modulation?
P0DTC8 Non-structural protein 8 (NS8) Unknown, host-virus modulation?
P0DTC9 Nucleoprotein (N) Viral genome packaging
P0DTD3 Uncharacterized protein 14 (NS14) Unknown, host-virus modulation?
P0DTD2 Protein 9b (NS9B) Unknown, host-virus modulation?
A0A663DJA2 Hypothetical ORF10 protein (NS10) Presumably not expressed