Leisingerviridae (taxid:2946185)

VIRION

Non-enveloped, head-tail structure with Sipho-type morphology. The head is about 55 nm in diameter. Tail is 210 nm in length and 10 nm in width, with a terminal knob.

GENOME

Linear, dsDNA genome of about 30 kb, circularly permuted and terminally redundant.

GENE EXPRESSION

ENZYMES

• Integrase [Int]
• Terminase [TermL]
• Cysteine protease (Peptidase C71) [Pro]

REPLICATION

CYTOPLASMIC

1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
2. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
3. Transcription and translation of early genes.
4. Replication of genomic DNA.
5. Transcription and translation of late genes
6. Assembly of an empty procapsid and packaging of the genome.
7. Viral tail fiber assembly and viral tail assembly.
8. Mature virions are released from the cell by lysis.