Mesyanzhinovviridae (taxid:2946162)

VIRION

Non-enveloped, head-tail structure with Sipho-type morphology. The prolate head is about 72 by 51 nm. Tail length is about 145 nm.

GENOME

Circular, dsDNA genome of about 60 kb, containing about 77 genes.

GENE EXPRESSION

ENZYMES

• DNA-dependent DNA polymerase A [A9J524]

REPLICATION

CYTOPLASMIC

1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
2. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
3. DNA genome is circularized or integrated into host chromosome
4. Transcription and translation of early genes
5. Replication of genomic DNA.
6. Transcription and translation of late genes
7. Assembly of an empty procapsid and packaging of the genome.
8. Viral tail fiber assembly and viral tail assembly.
9. Mature virions are released from the cell by lysis.