Class I fusion

Class I fusion proteins resemble influenzavirus hemagglutinin in their structure. Post-fusion, the active site has a trimer of alpha-helical coiled-coils. The binding domain is rich in alpha-helices and hydrophobic fusion peptides located near the N-terminus. Fusion conformation change can often be controlled by pH.

https://www.annualreviews.org/doi/10.1146/annurev-cellbio-101512-122422?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

https://www.cell.com/cell/pdf/S0092-8674(18)30231-9.pdf

https://www.nature.com/articles/nrmicro1326

https://www.annualreviews.org/doi/pdf/10.1146/annurev-virology-111821-093413