VIRION
Non-enveloped, head-tail structure with Sipho-type morphology. The icosahedral head is about 80 nm in diameter. The non-contractile tail is about 350 nm in length. Presence of 1 to 12 tRNAs.
GENOME
Linear dsDNA genome of about 69-76 kb, containing about 123-129 genes.
GENE EXPRESSION
REPLICATION
CYTOPLASMIC
- Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
- Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
- Transcription and translation of early genes.
- Replication of genomic DNA.
- Transcription and translation of late genes
- Assembly of an empty procapsid and packaging of the genome.
- Viral tail fiber assembly and viral tail assembly.
- Mature virions are released from the cell by lysis.