Assiduviridae (taxid:2946156)

Brussowvirus are temperate siphovirus.

VIRION

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Non-enveloped, head-tail structure with Sipho-type morphology. The icosahedral head is about 54 nm in diameter. The non-contractile tail is about 131 nm in length.

GENOME

Circular, dsDNA genome of about 55 kb, containing about 105 genes.

GENE EXPRESSION

ENZYMES

  • Integrase [Int]

REPLICATION

CYTOPLASMIC

  1. The phage attaches to the target cell adhesion receptor FhuA through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA, formation of viral genome concatemers.
  5. Transcription and translation of late genes
  6. Assembly of an empty procapsid and packaging of the genome through a headful mechanism.
  7. Viral tail fibers assembly and viral tail assembly.
  8. Mature virions are released from the cell by lysis.