Solendovirus (taxid:1232640)

VIRION

Non enveloped, large (50 nm diameter) icosahedral particles with a T=7 symmetry composed of 420 subunits. It has not been described whether handedness of capsid is laevo or dextro, here the pictures dsplays a laevo form.

GENOME

Monopartite, open circular, double stranded DNA of 7.7 kb. with each strand of viral DNA being interrupted by a site-specific discontinuity. ORF1 codes for the capsid protein, ORF2 for a movement protein, ORF3 for a replicase polyprotein and ORF4 product is a transactivator.

GENE EXPRESSION

ENZYMES

• Reverse transcriptase
  • RNA-dependent DNA polymerase [RT]
  • DNA-dependent DNA polymerase [RT]
• RNAse H [RT]
• Polyprotein protease (Peptidase A3) [PRO]

REPLICATION

CYTOPLASMIC / NUCLEAR

1. Attachment of viral proteins to host receptors mediates entry into the host cell.
2. The viral dsDNA is released into the nucleus.
3. Transcribed by host RNA polymerase II.
4. mRNA translation produces viral proteins.
5. Genomic RNA is retrotranscribed into new dsDNA genomes in the cytoplasm.
6. Genomes are encapsidated by the capsid protein and form new virions.
7. The virion infects either a new cell by plasmodesmata movement, or by insect vector uptake.