Hepatitis delta transcription
Related to: Hepatitis delta
Location: Host cell nucleus.
Transcription events:
The transcription process uses the genomic RNA as template to generate antigenomic RNA by rolling circle mechanism. This antigenomic RNA will then be used for translation. The transcription is insured by the host polymerase II protein which possesses a RdRP activity since the template is RNA and not DNA. Several studies suggest that Pol I or Pol III may also be involved in HDV transcription
RNA-Dependent replication and transcription of hepatitis delta virus RNA involve distinct cellular RNA polymerases
L E Modahl, T B Macnaughton, N Zhu, D L Johnson, M M Lai
Mol. Cell. Biol. August 2000; 20: 6030?6039
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L E Modahl, T B Macnaughton, N Zhu, D L Johnson, M M Lai
Mol. Cell. Biol. August 2000; 20: 6030?6039