Papillomaviridae (taxid:151340)

VIRION

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Non-enveloped. Small, icosahedral, about 60 nm in size. A single molecule of circular dsDNA is contained within the T=7 icosahedral capsid, which is composed of 72 pentamers.
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GENOME

Circular dsDNA, about 8 kb in size, associated with cellular histones in a chromatin-like complex.
On rare non-specific recombination, the viral genome can be integrated in host chromosome. This inactivates the integrated virus but can gives the host cell a replicative advantage sometimes leading to malignant tumours.

GENE EXPRESSION

Only one strand of the genome is transcribed and yield two classes of proteins expressed by alternative splicing :
a) Early Proteins: non-structural regulatory proteins (E1-E7).
b) Late Proteins: the structural proteins L1 and L2.

REPLICATION

NUCLEAR

Replication is divided in two distinct steps that are linked to the differentiation state of the host epithelial cell:

a) The plasmid replication takes place in the basal squamous epithelial cells. It corresponds to viral DNA replication in synchrony with the host cell chromosome in order to ensures an average of one viral genome per basal cell.

  1. Attachment of the viral proteins to host receptors mediates endocytosis into vesicles in the basal squamous epithelial cell.
  2. Transport to the nucleus and uncoating of the viral DNA.
  3. Early-region transcription and translation of the early proteins.
  4. Steady-state viral DNA nuclear replication. Requires the origin of DNA replication in cis and the viral E1 and E2 proteins in trans.

b) The vegetative replication, which occurs in differentiated keratinocytes. In these cells, which no longer undergo cellular DNA synthesis, there is a burst of viral DNA synthesis with active production of virions.

  1. Vegetative viral DNA synthesis.
  2. Transcription of the late region.
  3. Capsid proteins L1 and L2 synthesis.
  4. Nuclear capsid assembly and release of viruses.

Host-virus interaction

Adaptive immune response inhibition

The E5 protein in papillomaviruses plays a role in the inhibition of host adaptive response by down-regulating the cell surface expression of MHC class I .

Apoptosis modulation

The oncogenic type of human papillomaviruses (HPVs) E6 has among its functions the ability to prevent apoptosis of infected cells through its binding to FADD and caspase 8 .

Cell-cycle modulation

The E7 protein from the high-risk HPV type 18 forms a complex with cyclin E and regulates transit from G1 to S. HPV61 E7 binds cyclin A, which regulates transit through the S and G2/M phases of the cell cycle .

Innate immune response inhibition

Papillomaviruses inhibits the cascade leading to production of interferon-beta by targeting the IRF3 cellular protein. Indeed, The viral E6 protein is able to interact with host IRF3 and inhibits its transcriptional activity .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

575 entries grouped by strain

10 entries

Human papillomavirus 11 reference strain

Select_allDeselect_all
VE1_HPV11 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_HPV11 Protein E7
VL2_HPV11 Minor capsid protein L2
VE2_HPV11 Regulatory protein E2
VE6_HPV11 Protein E6
VL1_HPV11 Major capsid protein L1
VE4_HPV11 Protein E4
VE8E2_HPV11 Protein E8^E2C
VE5A_HPV11 Probable protein E5A
VE5B_HPV11 Probable protein E5B

9 entries

Human papillomavirus 31 reference strain

Select_allDeselect_all
VE7_HPV31 Protein E7
VE1_HPV31 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV31 Regulatory protein E2
VE6_HPV31 Protein E6
VL1_HPV31 Major capsid protein L1
VL2_HPV31 Minor capsid protein L2
VE8E2_HPV31 Protein E8^E2C
VE4_HPV31 Protein E4
VE5_HPV31 Probable protein E5

6 entries

Human papillomavirus 35 reference strain

Select_allDeselect_all
VE6_HPV35 Protein E6
VE1_HPV35 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV35 Regulatory protein E2
VE7_HPV35 Protein E7
VL2_HPV35 Minor capsid protein L2
VL1_HPV35 Major capsid protein L1

9 entries

Human papillomavirus 42 reference strain

Select_allDeselect_all
VE1_HPV42 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV42 Regulatory protein E2
VE6_HPV42 Protein E6
VE7_HPV42 Protein E7
VL2_HPV42 Minor capsid protein L2
VE8E2_HPV42 Protein E8^E2C
VE4_HPV42 Protein E4
VL1_HPV42 Major capsid protein L1
VE5_HPV42 Probable protein E5

9 entries

Human papillomavirus type 16 reference strain

Select_allDeselect_all
VL2_HPV16 Minor capsid protein L2
VE2_HPV16 Regulatory protein E2
VE7_HPV16 Protein E7
VE4_HPV16 Protein E4 (E1^E4)
VL1_HPV16 Major capsid protein L1
VE1_HPV16 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE5_HPV16 Probable protein E5
VE8E2_HPV16 Protein E8^E2C

9 entries

Human papillomavirus type 18 reference strain

Select_allDeselect_all
VE1_HPV18 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_HPV18 Protein E7
VE2_HPV18 Regulatory protein E2
VL2_HPV18 Minor capsid protein L2
VE4_HPV18 Protein E4
VL1_HPV18 Major capsid protein L1
VE8E2_HPV18 Protein E8^E2C
VE5_HPV18 Probable protein E5

8 entries

Cottontail rabbit papillomavirus (strain Kansas) (CRPV) (Papillomavirus sylvilagi) reference strain

Select_allDeselect_all
VL2_CRPVK Minor capsid protein L2
VE1_CRPVK Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_CRPVK Regulatory protein E2
VE6_CRPVK Protein E6
VE7_CRPVK Protein E7
VL1_CRPVK Major capsid protein L1
VE5_CRPVK Probable protein E5
VE4_CRPVK Probable protein E4

8 entries

Human papillomavirus 28 reference strain

Select_allDeselect_all
VE1_HPV28 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV28 Regulatory protein E2
VE7_HPV28 Protein E7
VL2_HPV28 Minor capsid protein L2
VE6_HPV28 Protein E6
VE8E2_HPV28 Protein E8^E2C
VL1_HPV28 Major capsid protein L1
VE4_HPV28 Protein E4

8 entries

Human papillomavirus 29 reference strain

Select_allDeselect_all
VE1_HPV29 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV29 Regulatory protein E2
VE7_HPV29 Protein E7
VL2_HPV29 Minor capsid protein L2
VE6_HPV29 Protein E6
VE8E2_HPV29 Protein E8^E2C
VL1_HPV29 Major capsid protein L1
VE4_HPV29 Protein E4

8 entries

Human papillomavirus 4 reference strain

Select_allDeselect_all
VE1_HPV04 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV04 Regulatory protein E2
VE6_HPV04 Protein E6
VE7_HPV04 Protein E7
VL2_HPV04 Minor capsid protein L2
VE8E2_HPV04 Protein E8^E2C
VE4_HPV04 Protein E4
VL1_HPV04 Major capsid protein L1

8 entries

Human papillomavirus 5 reference strain

Select_allDeselect_all
VL2_HPV05 Minor capsid protein L2
VE1_HPV05 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV05 Regulatory protein E2
VE6_HPV05 Protein E6
VE7_HPV05 Protein E7
VL1_HPV05 Major capsid protein L1
VE4_HPV05 Protein E4
VE8E2_HPV05 Protein E8^E2C

8 entries

Human papillomavirus 65 reference strain

Select_allDeselect_all
VE1_HPV65 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV65 Regulatory protein E2
VE6_HPV65 Protein E6
VE7_HPV65 Protein E7
VL2_HPV65 Minor capsid protein L2
VE8E2_HPV65 Protein E8^E2C
VE4_HPV65 Protein E4
VL1_HPV65 Major capsid protein L1

8 entries

Human papillomavirus type 41 reference strain

Select_allDeselect_all
VE1_HPV41 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV41 Regulatory protein E2
VE6_HPV41 Protein E6
VE7_HPV41 Protein E7
VL1_HPV41 Major capsid protein L1
VL2_HPV41 Minor capsid protein L2
VE4_HPV41 Protein E4
VE5_HPV41 Probable protein E5

8 entries

Human papillomavirus type 63 reference strain

Select_allDeselect_all
VE1_HPV63 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV63 Regulatory protein E2
VE6_HPV63 Protein E6
VE7_HPV63 Protein E7
VL2_HPV63 Minor capsid protein L2
VE8E2_HPV63 Protein E8^E2C
VE4_HPV63 Protein E4
VL1_HPV63 Major capsid protein L1

8 entries

Macaca mulata papillomavirus 1 (Rhpv 1) (Rhesus papillomavirus type 1) reference strain

Select_allDeselect_all
VE1_MMPV1 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_MMPV1 Regulatory protein E2
VE6_MMPV1 Protein E6
VE7_MMPV1 Protein E7
VL2_MMPV1 Minor capsid protein L2
VL1_MMPV1 Major capsid protein L1
VE4_MMPV1 Probable protein E4
VE5_MMPV1 Probable protein E5

8 entries

Pygmy chimpanzee papillomavirus type 1 (PCPV-1) reference strain

Select_allDeselect_all
VE1_PCPV1 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_PCPV1 Protein E6
VE7_PCPV1 Protein E7
VL2_PCPV1 Minor capsid protein L2
VE2_PCPV1 Regulatory protein E2
VL1_PCPV1 Major capsid protein L1
VE4_PCPV1 Probable protein E4
VE5_PCPV1 Probable protein E5

7 entries

Bovine papillomavirus type 3 reference strain

Select_allDeselect_all
VL2_BPV3 Minor capsid protein L2
VE2_BPV3 Regulatory protein E2
VE1_BPV3 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_BPV3 Protein E7
VE8E2_BPV3 Protein E8^E2C
VL1_BPV3 Major capsid protein L1
VE8_BPV3 Uncharacterized protein E8

7 entries

Bovine papillomavirus type 5 reference strain

Select_allDeselect_all
VE1_BPV5 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_BPV5 Minor capsid protein L2
VE2_BPV5 Regulatory protein E2
VE7_BPV5 Protein E7
VE6_BPV5 Protein E6
VE8E2_BPV5 Protein E8^E2C
VL1_BPV5 Major capsid protein L1

7 entries

Canine oral papillomavirus (strain Y62) (COPV) reference strain

Select_allDeselect_all
VE2_COPV6 Regulatory protein E2
VE1_COPV6 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_COPV6 Protein E7
VE6_COPV6 Protein E6
VL2_COPV6 Minor capsid protein L2
VL1_COPV6 Major capsid protein L1
VE4_COPV6 Probable protein E4

7 entries

European elk papillomavirus (EEPV) reference strain

Select_allDeselect_all
VE1_PAPVE Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_PAPVE Minor capsid protein L2
VE2_PAPVE Regulatory protein E2
VE6_PAPVE Protein E6
VE7_PAPVE Protein E7
VL1_PAPVE Major capsid protein L1
VE5_PAPVE Protein E5

7 entries

Human papillomavirus type 1 (Human papillomavirus type 1a) reference strain

Select_allDeselect_all
VL2_HPV1 Minor capsid protein L2
VE1_HPV1 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV1 Regulatory protein E2
VE7_HPV1 Protein E7
VE6_HPV1 Protein E6
VL1_HPV1 Major capsid protein L1
VE4_HPV1 Protein E4

6 entries

Human papillomavirus 15 reference strain

Select_allDeselect_all
VL2_HPV15 Minor capsid protein L2
VE2_HPV15 Regulatory protein E2
VE6_HPV15 Protein E6
VE7_HPV15 Protein E7
VE1_HPV15 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL1_HPV15 Major capsid protein L1

6 entries

Human papillomavirus 21 reference strain

Select_allDeselect_all
VE1_HPV21 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV21 Protein E6
VE2_HPV21 Regulatory protein E2
VE7_HPV21 Protein E7
VL2_HPV21 Minor capsid protein L2
VL1_HPV21 Major capsid protein L1

6 entries

Human papillomavirus 22 reference strain

Select_allDeselect_all
VE1_HPV22 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV22 Regulatory protein E2
VE6_HPV22 Protein E6
VE7_HPV22 Protein E7
VL2_HPV22 Minor capsid protein L2
VL1_HPV22 Major capsid protein L1

6 entries

Human papillomavirus 23 reference strain

Select_allDeselect_all
VE1_HPV23 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV23 Regulatory protein E2
VE6_HPV23 Protein E6
VE7_HPV23 Protein E7
VL2_HPV23 Minor capsid protein L2
VL1_HPV23 Major capsid protein L1

6 entries

Human papillomavirus 24 reference strain

Select_allDeselect_all
VE1_HPV24 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV24 Regulatory protein E2
VE6_HPV24 Protein E6
VE7_HPV24 Protein E7
VL2_HPV24 Minor capsid protein L2
VL1_HPV24 Major capsid protein L1

6 entries

Human papillomavirus 27 reference strain

Select_allDeselect_all
VE1_HPV27 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV27 Minor capsid protein L2
VE6_HPV27 Protein E6
VE7_HPV27 Protein E7
VL1_HPV27 Major capsid protein L1
VE2_HPV27 Regulatory protein E2

6 entries

Human papillomavirus 44 reference strain

Select_allDeselect_all
VE6_HPV44 Protein E6
VE7_HPV44 Protein E7
VE1_HPV44 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV44 Minor capsid protein L2
VL1_HPV44 Major capsid protein L1
VE2_HPV44 Regulatory protein E2

6 entries

Human papillomavirus 9 reference strain

Select_allDeselect_all
VL2_HPV09 Minor capsid protein L2
VE2_HPV09 Regulatory protein E2
VE6_HPV09 Protein E6
VE7_HPV09 Protein E7
VE1_HPV09 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL1_HPV09 Major capsid protein L1

6 entries

Human papillomavirus type 10 reference strain

Select_allDeselect_all
VE1_HPV10 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV10 Minor capsid protein L2
VE2_HPV10 Regulatory protein E2
VE6_HPV10 Protein E6
VE7_HPV10 Protein E7
VL1_HPV10 Major capsid protein L1

6 entries

Human papillomavirus type 32 reference strain

Select_allDeselect_all
VE1_HPV32 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV32 Minor capsid protein L2
VE2_HPV32 Regulatory protein E2
VE6_HPV32 Protein E6
VE7_HPV32 Protein E7
VL1_HPV32 Major capsid protein L1

6 entries

Human papillomavirus type 48 reference strain

Select_allDeselect_all
VE6_HPV48 Protein E6
VE7_HPV48 Protein E7
VE1_HPV48 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV48 Regulatory protein E2
VL2_HPV48 Minor capsid protein L2
VL1_HPV48 Major capsid protein L1

6 entries

Human papillomavirus type 60 reference strain

Select_allDeselect_all
VE6_HPV60 Protein E6
VE7_HPV60 Protein E7
VE1_HPV60 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV60 Regulatory protein E2
VL2_HPV60 Minor capsid protein L2
VL1_HPV60 Major capsid protein L1

5 entries

Human papillomavirus 56 reference strain

Select_allDeselect_all
VE6_HPV56 Protein E6
VL2_HPV56 Minor capsid protein L2
VE2_HPV56 Regulatory protein E2
VE7_HPV56 Protein E7
VL1_HPV56 Major capsid protein L1

4 entries

Human papillomavirus type 50 reference strain

Select_allDeselect_all
VE7_HPV50 Protein E7
VE2_HPV50 Regulatory protein E2
VL2_HPV50 Minor capsid protein L2
VL1_HPV50 Major capsid protein L1

3 entries

Mastomys natalensis papillomavirus (isolate African multimammate rat) (MnPV) reference strain

Select_allDeselect_all
VE1_MNPVA Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_MNPVA Protein E6
VE8E2_MNPVA Protein E8^E2C

2 entries

Human papillomavirus 62 reference strain

Select_allDeselect_all
VL2_HPV62 Minor capsid protein L2
VL1_HPV62 Major capsid protein L1

2 entries

Human papillomavirus 82 reference strain

Select_allDeselect_all
VL2_HPV82 Minor capsid protein L2
VL1_HPV82 Major capsid protein L1

2 entries

Human papillomavirus type 94 reference strain

Select_allDeselect_all
VE7_HPV94 Protein E7
VE6_HPV94 Protein E6

1 entry

Human papillomavirus 72 reference strain

VE1_HPV72 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)

1 entry

Human papillomavirus 73 reference strain

VE1_HPV73 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)

11 entries

Bos taurus papillomavirus 4 (Bovine papillomavirus 4)

Select_allDeselect_all
VL2_BPV4 Minor capsid protein L2
VE1_BPV4 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_BPV4 Regulatory protein E2
VE7_BPV4 Protein E7
VL1_BPV4 Major capsid protein L1
VL3_BPV4 Probable protein L3
VE3_BPV4 Probable protein E3
VE4_BPV4 Probable protein E4
VE5A_BPV4 Probable protein E5A
VE5B_BPV4 Probable protein E5B
VE8_BPV4 Uncharacterized protein E8

10 entries

Bos taurus papillomavirus 2 (Bovine papillomavirus 2)

Select_allDeselect_all
VE1_BPV2 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_BPV2 Minor capsid protein L2
VE6_BPV2 Protein E6
VE7_BPV2 Protein E7
VL1_BPV2 Major capsid protein L1
VE5_BPV2 Protein E5
VE2_BPV2 Regulatory protein E2
VE4_BPV2 Probable protein E4
VE3_BPV2 Probable protein E3
VE8_BPV2 Uncharacterized protein E8

9 entries

Bovine papillomavirus type 1

Select_allDeselect_all
VE1_BPV1 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_BPV1 Regulatory protein E2
VL2_BPV1 Minor capsid protein L2
VE6_BPV1 Protein E6
VE7_BPV1 Protein E7
VE5_BPV1 Protein E5
VL1_BPV1 Major capsid protein L1
VE4_BPV1 Protein E4
VE8E2_BPV1 Protein E8^E2C

9 entries

Human papillomavirus 13

Select_allDeselect_all
VE1_HPV13 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV13 Protein E6
VE7_HPV13 Protein E7
VL2_HPV13 Minor capsid protein L2
VE8E2_HPV13 Protein E8^E2C
VE2_HPV13 Regulatory protein E2
VE4_HPV13 Protein E4
VL1_HPV13 Major capsid protein L1
VE5_HPV13 Probable protein E5

9 entries

Human papillomavirus 33

Select_allDeselect_all
VE6_HPV33 Protein E6
VL2_HPV33 Minor capsid protein L2
VE1_HPV33 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV33 Regulatory protein E2
VE7_HPV33 Protein E7
VL1_HPV33 Major capsid protein L1
VE4_HPV33 Protein E4 (E1^E4)
VE8E2_HPV33 Protein E8^E2C
VE5_HPV33 Probable protein E5

3 entries

Human papillomavirus 35

Select_allDeselect_all
VE8E2_HPV35 Protein E8^E2C
VE4_HPV35 Protein E4
VE5_HPV35 Probable protein E5

9 entries

Human papillomavirus 39

Select_allDeselect_all
VE6_HPV39 Protein E6
VE1_HPV39 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV39 Regulatory protein E2
VE7_HPV39 Protein E7
VL2_HPV39 Minor capsid protein L2
VE8E2_HPV39 Protein E8^E2C
VE4_HPV39 Protein E4
VL1_HPV39 Major capsid protein L1
VE5_HPV39 Probable protein E5

9 entries

Human papillomavirus 51

Select_allDeselect_all
VL2_HPV51 Minor capsid protein L2
VE1_HPV51 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV51 Regulatory protein E2
VE6_HPV51 Protein E6
VE7_HPV51 Protein E7
VE8E2_HPV51 Protein E8^E2C
VL1_HPV51 Major capsid protein L1
VE4_HPV51 Protein E4
VE5_HPV51 Probable protein E5

9 entries

Human papillomavirus 58

Select_allDeselect_all
VL1_HPV58 Major capsid protein L1
VL2_HPV58 Minor capsid protein L2
VE1_HPV58 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV58 Regulatory protein E2
VE6_HPV58 Protein E6
VE7_HPV58 Protein E7
VE8E2_HPV58 Protein E8^E2C
VE4_HPV58 Protein E4
VE5_HPV58 Probable protein E5

9 entries

Human papillomavirus type 5b

Select_allDeselect_all
VL2_HPV5B Minor capsid protein L2
VE1_HPV5B Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV5B Regulatory protein E2
VE6_HPV5B Protein E6
VE7_HPV5B Protein E7
VL1_HPV5B Major capsid protein L1
VE4_HPV5B Protein E4
VL3_HPV5B Probable protein L3
VE5_HPV5B Probable protein E5

9 entries

Human papillomavirus type 6b

Select_allDeselect_all
VL2_HPV6B Minor capsid protein L2
VE1_HPV6B Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV6B Regulatory protein E2
VE4_HPV6B Protein E4 (E1^E4)
VE6_HPV6B Protein E6
VE7_HPV6B Protein E7
VL1_HPV6B Major capsid protein L1
VE5A_HPV6B Probable protein E5A
VE5B_HPV6B Probable protein E5B

8 entries

Human papillomavirus 47

Select_allDeselect_all
VE1_HPV47 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV47 Regulatory protein E2
VE6_HPV47 Protein E6
VE7_HPV47 Protein E7
VL2_HPV47 Minor capsid protein L2
VE8E2_HPV47 Protein E8^E2C
VE4_HPV47 Protein E4
VL1_HPV47 Major capsid protein L1

8 entries

Human papillomavirus 57

Select_allDeselect_all
VE1_HPV57 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV57 Regulatory protein E2
VE6_HPV57 Protein E6
VE7_HPV57 Protein E7
VL2_HPV57 Minor capsid protein L2
VE8E2_HPV57 Protein E8^E2C
VE4_HPV57 Protein E4
VL1_HPV57 Major capsid protein L1

8 entries

Human papillomavirus type 54

Select_allDeselect_all
VE1_HPV54 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV54 Protein E6
VE7_HPV54 Protein E7
VE2_HPV54 Regulatory protein E2
VL2_HPV54 Minor capsid protein L2
VE8E2_HPV54 Protein E8^E2C
VL1_HPV54 Major capsid protein L1
VE4_HPV54 Protein E4

8 entries

Human papillomavirus type 6a

Select_allDeselect_all
VE6_HPV6A Protein E6
VE7_HPV6A Protein E7
VE1_HPV6A Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV6A Regulatory protein E2
VL2_HPV6A Minor capsid protein L2
VL1_HPV6A Major capsid protein L1
VE4_HPV6A Protein E4
VE5A_HPV6A Probable protein E5A

8 entries

Human papillomavirus type 8

Select_allDeselect_all
VL2_HPV08 Minor capsid protein L2
VE1_HPV08 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV08 Regulatory protein E2
VE6_HPV08 Protein E6
VE7_HPV08 Protein E7
VL1_HPV08 Major capsid protein L1
VE4_HPV08 Protein E4
VE8E2_HPV08 Protein E8^E2C

8 entries

Odocoileus virginianus papillomavirus 1 (DPV) (Deer papillomavirus)

Select_allDeselect_all
VE1_OVPVD Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_OVPVD Minor capsid protein L2
VE2_OVPVD Regulatory protein E2
VE6_OVPVD Protein E6
VE7_OVPVD Protein E7
VL1_OVPVD Major capsid protein L1
VL3_OVPVD Probable protein L3
VE4_OVPVD Probable protein E4

7 entries

Human papillomavirus type 2a

Select_allDeselect_all
VE1_HPV2A Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV2A Regulatory protein E2
VE6_HPV2A Protein E6
VE7_HPV2A Protein E7
VL2_HPV2A Minor capsid protein L2
VE4_HPV2A Protein E4
VL1_HPV2A Major capsid protein L1

7 entries

Human papillomavirus type 70

Select_allDeselect_all
VE1_HPV70 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV70 Regulatory protein E2
VE7_HPV70 Protein E7
VL2_HPV70 Minor capsid protein L2
VE6_HPV70 Protein E6
VL1_HPV70 Major capsid protein L1
VE5_HPV70 Probable protein E5

6 entries

Human papillomavirus 12

Select_allDeselect_all
VE1_HPV12 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV12 Minor capsid protein L2
VE2_HPV12 Regulatory protein E2
VE6_HPV12 Protein E6
VE7_HPV12 Protein E7
VL1_HPV12 Major capsid protein L1

6 entries

Human papillomavirus 17

Select_allDeselect_all
VL2_HPV17 Minor capsid protein L2
VE2_HPV17 Regulatory protein E2
VE6_HPV17 Protein E6
VE7_HPV17 Protein E7
VE1_HPV17 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL1_HPV17 Major capsid protein L1

6 entries

Human papillomavirus 19

Select_allDeselect_all
VE1_HPV19 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV19 Minor capsid protein L2
VE2_HPV19 Regulatory protein E2
VE6_HPV19 Protein E6
VE7_HPV19 Protein E7
VL1_HPV19 Major capsid protein L1

6 entries

Human papillomavirus 20

Select_allDeselect_all
VE1_HPV20 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV20 Protein E6
VE2_HPV20 Regulatory protein E2
VE7_HPV20 Protein E7
VL2_HPV20 Minor capsid protein L2
VL1_HPV20 Major capsid protein L1

6 entries

Human papillomavirus 25

Select_allDeselect_all
VE1_HPV25 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV25 Protein E6
VL2_HPV25 Minor capsid protein L2
VE2_HPV25 Regulatory protein E2
VE7_HPV25 Protein E7
VL1_HPV25 Major capsid protein L1

6 entries

Human papillomavirus 30

Select_allDeselect_all
VL2_HPV30 Minor capsid protein L2
VE2_HPV30 Regulatory protein E2
VE6_HPV30 Protein E6
VE7_HPV30 Protein E7
VE1_HPV30 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL1_HPV30 Major capsid protein L1

6 entries

Human papillomavirus 36

Select_allDeselect_all
VE1_HPV36 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV36 Regulatory protein E2
VE6_HPV36 Protein E6
VE7_HPV36 Protein E7
VL2_HPV36 Minor capsid protein L2
VL1_HPV36 Major capsid protein L1

6 entries

Human papillomavirus 38

Select_allDeselect_all
VE6_HPV38 Protein E6
VE7_HPV38 Protein E7
VE1_HPV38 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV38 Regulatory protein E2
VL2_HPV38 Minor capsid protein L2
VL1_HPV38 Major capsid protein L1

6 entries

Human papillomavirus 40

Select_allDeselect_all
VE1_HPV40 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV40 Minor capsid protein L2
VE2_HPV40 Regulatory protein E2
VE6_HPV40 Protein E6
VE7_HPV40 Protein E7
VL1_HPV40 Major capsid protein L1

6 entries

Human papillomavirus 45

Select_allDeselect_all
VE6_HPV45 Protein E6
VE7_HPV45 Protein E7
VE1_HPV45 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV45 Minor capsid protein L2
VE2_HPV45 Regulatory protein E2
VL1_HPV45 Major capsid protein L1

6 entries

Human papillomavirus 52

Select_allDeselect_all
VE1_HPV52 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV52 Minor capsid protein L2
VE2_HPV52 Regulatory protein E2
VE6_HPV52 Protein E6
VE7_HPV52 Protein E7
VL1_HPV52 Major capsid protein L1

6 entries

Human papillomavirus 66

Select_allDeselect_all
VE6_HPV66 Protein E6
VE7_HPV66 Protein E7
VE1_HPV66 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV66 Regulatory protein E2
VL2_HPV66 Minor capsid protein L2
VL1_HPV66 Major capsid protein L1

6 entries

Human papillomavirus 69

Select_allDeselect_all
VL2_HPV69 Minor capsid protein L2
VE2_HPV69 Regulatory protein E2
VE1_HPV69 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_HPV69 Protein E7
VE6_HPV69 Protein E6
VL1_HPV69 Major capsid protein L1

6 entries

Human papillomavirus 7

Select_allDeselect_all
VL2_HPV07 Minor capsid protein L2
VE2_HPV07 Regulatory protein E2
VE6_HPV07 Protein E6
VE7_HPV07 Protein E7
VE1_HPV07 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL1_HPV07 Major capsid protein L1

6 entries

Human papillomavirus type 26

Select_allDeselect_all
VE1_HPV26 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV26 Minor capsid protein L2
VE2_HPV26 Regulatory protein E2
VE6_HPV26 Protein E6
VE7_HPV26 Protein E7
VL1_HPV26 Major capsid protein L1

6 entries

Human papillomavirus type 34

Select_allDeselect_all
VE1_HPV34 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV34 Minor capsid protein L2
VE2_HPV34 Regulatory protein E2
VE6_HPV34 Protein E6
VE7_HPV34 Protein E7
VL1_HPV34 Major capsid protein L1

6 entries

Human papillomavirus type 49

Select_allDeselect_all
VE1_HPV49 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV49 Minor capsid protein L2
VE2_HPV49 Regulatory protein E2
VE6_HPV49 Protein E6
VE7_HPV49 Protein E7
VL1_HPV49 Major capsid protein L1

6 entries

Human papillomavirus type 61

Select_allDeselect_all
VE1_HPV61 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV61 Protein E6
VE7_HPV61 Protein E7
VE2_HPV61 Regulatory protein E2
VL2_HPV61 Minor capsid protein L2
VL1_HPV61 Major capsid protein L1

5 entries

Human papillomavirus 14

Select_allDeselect_all
VE1_HPV14 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE6_HPV14 Protein E6
VL2_HPV14 Minor capsid protein L2
VE2_HPV14 Regulatory protein E2
VL1_HPV14 Major capsid protein L1

5 entries

Human papillomavirus 3

Select_allDeselect_all
VE1_HPV03 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VL2_HPV03 Minor capsid protein L2
VE2_HPV03 Regulatory protein E2
VE6_HPV03 Protein E6
VL1_HPV03 Major capsid protein L1

5 entries

Human papillomavirus 37

Select_allDeselect_all
VE7_HPV37 Protein E7
VE1_HPV37 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE2_HPV37 Regulatory protein E2
VL2_HPV37 Minor capsid protein L2
VL1_HPV37 Major capsid protein L1

5 entries

Human papillomavirus type 53

Select_allDeselect_all
VL2_HPV53 Minor capsid protein L2
VE2_HPV53 Regulatory protein E2
VE6_HPV53 Protein E6
VE7_HPV53 Protein E7
VL1_HPV53 Major capsid protein L1

4 entries

Bos taurus papillomavirus 6 (Bovine papillomavirus 6)

Select_allDeselect_all
VE2_BPV6 Regulatory protein E2
VE1_BPV6 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)
VE7_BPV6 Protein E7
VE8_BPV6 Uncharacterized protein E8

4 entries

Human papillomavirus type 55

Select_allDeselect_all
VE7_HPV55 Protein E7
VE2_HPV55 Regulatory protein E2
VL2_HPV55 Minor capsid protein L2
VL1_HPV55 Major capsid protein L1

4 entries

Human papillomavirus type ME180

Select_allDeselect_all
VE6_HPVME Protein E6
VE7_HPVME Protein E7
VL2_HPVME Minor capsid protein L2
VL1_HPVME Major capsid protein L1

3 entries

Human papillomavirus 43

Select_allDeselect_all
VE6_HPV43 Protein E6
VL2_HPV43 Minor capsid protein L2
VL1_HPV43 Major capsid protein L1

3 entries

Human papillomavirus 68

Select_allDeselect_all
VE6_HPV68 Protein E6
VE7_HPV68 Protein E7
VL1_HPV68 Major capsid protein L1

3 entries

Human papillomavirus type 6c

Select_allDeselect_all
VE4_HPV6C Probable protein E4
VE5A_HPV6C Probable protein E5A
VE5B_HPV6C Probable protein E5B

2 entries

Cottontail rabbit papillomavirus (strain Washington B) (CRPV) (Papillomavirus sylvilagi)

Select_allDeselect_all
VE7_CRPVW Protein E7
VE5_CRPVW Probable protein E5

2 entries

Human papillomavirus 67

Select_allDeselect_all
VL2_HPV67 Minor capsid protein L2
VL1_HPV67 Major capsid protein L1

1 entry

Human papillomavirus 59

VE1_HPV59 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)

1 entry

Human papillomavirus type RTRX7

VE1_HPVR7 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)

1 entry

Micromys minutus papillomavirus (MmPV) (Old world harvest mouse papillomavirus)

VE6_MMPV Protein E6

1 entry

Pygmy chimpanzee papillomavirus type 1C (PCPV-1C)

VE1_PCPVC Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1)

1 entry

Reindeer papillomavirus (RPV)

VE5_PAPVR Protein E5