Lambdavirus (taxid:186765)

VIRION

Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).
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GENOME

Linear, dsDNA genome of about 48 kb, containing about 70 genes.

GENE EXPRESSION

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.
DB LINKS image image

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TAXONOMY Group I: dsDNA viruses
Order: Unassigned
Family: Unassigned
Genus: Lambdavirus
SPECIES
Escherichia virus Lambda
 Escherichia virus DE3
 Escherichia virus HK629
 Escherichia virus HK630
REFERENCE STRAIN Enterobacteria phage λ
Sequence | Genome | Proteome

Host

NATURAL HOSTS Bacteria.

Ecology and disease

GEOGRAPHY Worldwide
TRANSMISSION Passive diffusion through medium
ANTIVIRAL DRUGS None

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

107 entries grouped by strain

62 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

Select_allDeselect_all
HOLIN_LAMBD Antiholin (Lysis inhibitor S-107)
ENLYS_LAMBD Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

pdb 1AM7; 1D9U; 3D3D

TERS_LAMBD Terminase small subunit (EC 3.6.4.-) (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)

pdb 1J9I; 6HN7; 7LW0

TERL_LAMBD Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA) [Includes: ...
SCAF_LAMBD Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
SPAN2_LAMBD Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
SPAN1_LAMBD Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
RPC1_LAMBD Repressor protein cI

pdb 1F39; 1KCA; 1LLI; 1LMB; 1LRP; 1RIO; 3BDN; 3KZ3; 3WOA; 5ZCA; 7JVT

RCRO_LAMBD Regulatory protein cro

pdb 1COP; 1D1L; 1D1M; 1ORC; 2A63; 2ECS; 2ORC; 2OVG; 3ORC; 4CRO; 5CRO; 6CRO

REGN_LAMBD Antitermination protein N (Regulatory protein N) (PN)

pdb 1QFQ; 5LM7; 5MS0; 6GOV

REGQ_LAMBD Antitermination protein Q

pdb 4MO1; 7UBJ; 7UBK; 7UBL; 7UBM; 7UBN

VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)

pdb 1AE9; 1KJK; 1P7D; 1Z19; 1Z1B; 1Z1G; 2OXO; 2WCC; 5J0N

PORTL_LAMBD Portal protein B (GpB) (Minor capsid protein B) [Cleaved into: Protein B*]
DECO_LAMBD Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)

pdb 1C5E; 1TCZ; 1VD0; 5MFD; 7VII; 7VIK

TIPJ_LAMBD Tip attachment protein J (Central tail fiber) (Host specificity protein J)
RPC2_LAMBD Transcriptional activator II

pdb 1XWR; 1ZPQ; 1ZS4; 8IGR

VRPO_LAMBD Replication protein O
EXO_LAMBD Exonuclease (EC 3.1.11.3)

pdb 1AVQ; 3SLP; 3SM4; 4WUZ; 6M9K

VXIS_LAMBD Excisionase

pdb 1LX8; 1RH6; 2IEF; 2OG0; 5J0N; 6P0S; 6P0T; 6P0U

GAM_LAMBD Host-nuclease inhibitor protein gam

pdb 2UUZ; 2UV1; 5MBV

FI_LAMBD DNA-packaging protein FI

pdb 2LSM

CAPSD_LAMBD Major capsid protein (Gene product E) (gpE) (Major head protein)

pdb 7SJ5; 7VI9; 7VIA; 7VII; 7VIK

FII_LAMBD Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)

pdb 1K0H; 2KX4

TIPK_LAMBD Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
TTTP_LAMBD Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail ...

pdb 1Z1Z; 3FZ2; 3FZB

TUBE_LAMBD Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)

pdb 2K4Q; 2L04; 6P3E; 7T2E; 7T4F

G_LAMBD Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) ...
GT_LAMBD Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)
TMP_LAMBD Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry ...
TIPL_LAMBD Tail tip protein L
FIBER_LAMBD Tail fiber protein (stf) (Gene product 27) (gp27)
PP_LAMBD Serine/threonine-protein phosphatase (EC 3.1.3.16)

pdb 1G5B

RPC3_LAMBD Protease inhibitor III
VRPP_LAMBD Replication protein P

pdb 6BBM

VBET_LAMBD Recombination protein bet

pdb 6M9K; 7UJL

VLOM_LAMBD Outer membrane protein lom (ORF 206A)
RAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein)
TIPI_LAMBD Tail tip assembly protein I
COMPL_LAMBD Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
TIPM_LAMBD Tail tip protein M
TFA_LAMBD Tail fiber assembly protein
VKIL_LAMBD Protein kil
REXB_LAMBD Protein rexB
SIEB_LAMBD Superinfection exclusion protein B
HCP_LAMBD Head completion protein (HCP) (Head-tail joining protein W) (gpW)

pdb 1HYW; 2L6Q; 2L6R

EA47_LAMBD Protein ea47
EA31_LAMBD Protein ea31
EA59_LAMBD Protein ea59
EA85_LAMBD Protein ea8.5
EA22_LAMBD Protein ea22

pdb 8DSX

VREN_LAMBD Protein ren
NINB_LAMBD Protein ninB

pdb 1PC6

Y290_LAMBD Uncharacterized nin region protein ORF290
NIND_LAMBD Protein ninD
NINE_LAMBD Protein ninE (Nin60)
NINF_LAMBD Protein ninF
NING_LAMBD Protein ninG
NINH_LAMBD Protein ninH
Y64_LAMBD Putative uncharacterized protein ORF64
EA10_LAMBD Protein ea10
REXA_LAMBD Protein rexA
BOR_LAMBD Lipoprotein bor

18 entries

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Select_allDeselect_all
HOLIN_BPP21 Antiholin
TERL_BPP21 Terminase, large subunit (DNA-packaging protein) (DNA-packaging protein gp2) (Gene product 2) (gp2) ...
SPAN2_BPP21 Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
VINT_BPP21 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
SPAN1_BPP21 Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
ENLYS_BPP21 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)

pdb 3HDE; 3HDF

VG05_BPP21 Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5) [Cleaved into: Scaffold ...
VXIS_BPP21 Excisionase
PORTL_BPP21 Portal protein B (GpB) (Minor capsid protein B)
DECO_BPP21 Head decoration protein (Head protein GPshp)

pdb 1TD0; 1TD3; 1TD4

CAPSD_BPP21 Major capsid protein (Gene product 7) (Gene product E) (gpE) (Major head protein)
TERS_BPP21 Terminase, small subunit (Gp1)

pdb 7LWR

W_BPP21 Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining ...
YG78_BPP21 Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region
NINB_BPP21 Protein ninB
NINE_BPP21 Protein ninE
NINF_BPP21 Protein ninF
NING_BPP21 Protein ninG

8 entries

Enterobacteria phage H19B (Bacteriophage H19B)

Select_allDeselect_all
STXB_BPH19 Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) ...

pdb 1BOS; 1C48; 1C4Q; 1CQF; 1CZG; 1CZW; 1D1I; 1QNU; 2XSC; 4ULL

STXA_BPH19 Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verocytotoxin 1 ...
ENLYS_BPH19 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
NINE_BPH19 Protein ninE
NINF_BPH19 Protein ninF
NING_BPH19 Protein ninG
NINH_BPH19 Protein ninH
REGQ_BPH19 Antitermination protein Q

7 entries

Enterobacteria phage 82 (Bacteriophage 82)

Select_allDeselect_all
RUSA_BP82 Crossover junction endodeoxyribonuclease rusA (EC 3.1.21.10) (Holliday junction nuclease rusA) ...
REGQ_BP82 Antitermination protein Q
YBCO_BP82 Putative nuclease ybcO (EC 3.1.-.-)
YLCH_BP82 Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)
YBCN_BP82 Uncharacterized protein in rusA 5'region (ORF151)
NINE_BP82 Protein ninE
YLCG_BP82 Uncharacterized protein in rusA 3'region (ORF45)

5 entries

Enterobacteria phage 434 (Bacteriophage 434)

Select_allDeselect_all
VINT_BP434 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
RCRO_BP434 Regulatory protein cro (Antirepressor)

pdb 1ZUG; 2CRO; 3CRO

RPC2_BP434 Regulatory protein CII
VXIS_BP434 Excisionase
REXA_BP434 Protein rexA

2 entries

Corynephage beta

Select_allDeselect_all
DTX_CORBE Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...

pdb 1DDT; 1DTP; 1F0L; 1MDT; 1SGK; 1TOX; 1XDT; 4AE0; 4AE1

DTXH_CORBE Diphtheria toxin homolog CRM228 [Cleaved into: Diphtheria toxin homolog CRM228 fragment A; ...

2 entries

Enterobacteria phage PA-2 (Bacteriophage PA-2)

Select_allDeselect_all
ENLYS_BPPA2 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
PORI_BPPA2 Outer membrane porin protein LC

1 entry

Bacillus phage SP02 (Bacteriophage SP02)

DPOL_BPSP2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

1 entry

Bacillus phage rho11s (Bacteriophage rho-11s)

MTBR_BPRH1 Orphan methyltransferase M.Rho11sI (M.Rho11sI) (EC 2.1.1.37) (Bsu P11s) (Cytosine-specific ...

1 entry

Corynephage omega

DTX_COROM Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...