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Human immunodeficiency virus 1 (taxid:11676)

Molecular biology

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Enveloped, spherical to pleomorphic in shape, 80-100 nm in diameter. Mature capsid contains 1572 capsid proteins.

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Monopartite, linear, dimeric, ssRNA(+) genome of 9,75 kb, with a 5'-cap and a 3'poly-A tail. There are two long terminal repeats (LTRs) of about 600nt long at the 5' and 3' ends. The LTRs contain the U3, R, and U5 regions. There are also a primer binding site (PBS) at the 5'end and a polypurine tract (PPT) at the 3'end.

GENE EXPRESSION

The integrated provirus utilizes the promotor elements in the 5' LTR to drive transcription. This gives rise to the unspliced full length mRNA that will serve as genomic RNA to be packaged into virions or used as a template for translation of gag and gag-(pro)pol (1 ribosomal frameshift) polyproteins. The uncompletely spliced mRNAs encode env that is cleaved into SU and TM envelope proteins, and the accessory proteins vif, vpu, and vpr. Completely spliced mRNAs encode Rev, Tat and Nef accessory proteins. Rev escorts unspliced and uncompletely spliced RNAs out of the nucleus of infected cells.

ENZYMES

REPLICATION

NUCLEAR

Lytic replication:

  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell's genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Latent replication : replication as a provirus integrated in the host chromosome.

DB LINKS image image

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HIV sequences: Los Alamos
HIV drug resistance: Stanford
TAXONOMY Group VI: RNA reverse transcribing viruses
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Subfamily: Orthoretrovirinae
Genus: Lentivirus
VIRUS Human immunodeficiency virus 1 (HIV-1)
REFERENCE STRAIN HIV-1 group M subtype B strain HxB2
Sequence | Genome assembly | Proteome
HOST Human
CELL TROPISM CD4+ T cells, macrophages and dendritic cells.
CELL RECEPTOR (S) CD4
CCR5
CXCR4
Glycosphingolipids (->SugarBindDB)

Epidemiology

GEOGRAPHY worldwide
ASSOCIATED DISEASES Acquired ImmunoDeficiency Syndrome (AIDS)
TRANSMISSION Sexual contact, blood, breast feeding
VACCINE
ANTIVIRAL DRUGS HIV antiretroviral drugs

Reference strains

HIV-1 REFERENCE STRAIN HIV-1 subtype B strain HxB2
Sequence | Genome | Proteome

EXPERIMENTAL CLONE PNL4.3 pNL4-3 is a subtype B strain that is normally used as the reference sequence for HIV drug resistance studies. It is a recombinant (infectious) proviral clone that contains DNA from HIV isolates NY5 (5' half) and BRU (3' half). The site of recombination is the EcoRI site at positions 5743-5748.
Sequence | Proteome

GROUP O REFERENCE STRAIN Group O seems to be endemic and largely confined to Cameroon and neighboring countries in West Central Africa, where these viruses represent a small minority of HIV-1 strains. (Pubmed)

HIV-1 isolate ANT70
Sequence | Proteome

GROUP N REFERENCE STRAIN The group N is confined to Cameroon. (Pubmed)

HIV-1 isolate YBF30
Sequence | Proteome
GROUP M REFERENCE STRAINS

HIV-1 group M is responsible for the worlwide pandemy of AIDS. It is subdivised into 9 subtypes (A-F), and several CRF.
(Reference strains have been chosen in collaboration with Tulio de Oliveira, Bioafrica.net)

Subtype A1: HIV-1 isolate U455
Sequence | Proteome

Subtype B: HIV-1 strain HxB2
Sequence | Genome | Proteome

Subtype C: HIV-1 isolate TV001
Sequence | Proteome

Subtype D: HIV-1 isolate ELI
Sequence | Proteome

Subtype F1: HIV-1 isolate 93BR020
Sequence | Proteome

Subtype F2: HIV-1 isolate MP255
Sequence | Proteome

Subtype G: HIV-1 isolate 92BR025
Sequence | Proteome

Subtype H: HIV-1 isolate 90CF056
Sequence | Proteome

Subtype J: HIV-1 isolate SE9173
Sequence | Proteome

Subtype K: HIV-1 isolate 96CM-MP535
Sequence | Proteome

CRF01_AE: HIV-1 isolate 90CF11697
Sequence | Proteome

CRF02_AG: HIV-1 isolate 97CM.MP807
Sequence | Proteome

Epidemiology

Global map of HIV infection source WHO/UNAIDS

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HIV subtypes

HIV viruses are subdivised into groups, subtypes and CRF. Groups N and O are recent and so far restricted to cameroon. The vast majority of HIV-1 strains found worldwide belongs to Group M (Major). This group is subdivised into 9 subtypes (A-F), and several CRF (circulating recombinant form).

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Source Peeters, M.

Replication cycle

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  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell's genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

353 entries grouped by strain

9 entries

Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain

Select_allDeselect_all
ENV_HV1MA Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2X4O

POL_HV1MA Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1HHJ; 3IXO; 8T4E

GAG_HV1MA Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
NEF_HV1MA Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 3W0W; 3WL9

TAT_HV1MA Protein Tat (Transactivating regulatory protein)

pdb 1K5K

VIF_HV1MA Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1MA Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1MA Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1MA Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1A2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 4OBD; 4OBF; 4OBG; 4OBH; 4OBJ; 4OBK; 4QJ2; 4QJ6; 4QJ7; 4QJ8; 4QJ9; 4QJA

POL_HV1A2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1AID; 1B6J; 1B6K; 1B6L; 1B6M; 1B6P; 1CPI; 1D4K; 1D4L; 1F7A; 1KJ4; 1KJ7; 1KJF; 1KJG; 1KJH; 1KZK; 1MT7; 1MT8; 1MT9; 1MTB; 1MTR; 1N49; 1T3R; 1TSQ; 1TSU; 1YTG; 1YTH; 1Z1H; 1Z1R; 2AID; 2F3K; 2FGU; 2FGV; 2FNS; 2FNT; 2J9J; 2J9K; 2JE4; 2NXD; 2NXL; 2NXM; 2Q3K; 2QHY; 2QHZ; 2QI0; 2QI1; 2QI3; 2QI4; 2QI5; 2QI6; 2QI7; 3AID; 3BXR; 3BXS; 3EKP; 3EKQ; 3EKT; 3EKV; 3EKW; 3EKX; 3EKY; 3EL0; 3EL1; 3EL4; 3EL5; 3EL9; 3EM3; 3EM4; 3EM6; 3FSM; 3GI0; 3GI4; 3GI5; 3GI6; 3HAU; 3HAW; 3HBO; 3HDK; 3HLO; 3HVP; 3HZC; 3I2L; 3I7E; 3IAW; 3KA2; 3LZV; 3MXD; 3MXE; 3NWQ; 3NWX; 3NXN; 3NYG; 3O9F; 3O9G; 3O9H; 3O9I; 3OXV; 3OXW; 3OXX; 3OY4; 3R4B; 4EP2; 4EP3; 4EPJ; 4EQ0; 4EQJ; 4F73; 4F74; 4F75; 4F76; 4HVP; 4OBD; 4OBF; 4OBG; 4OBH; 4OBJ; 4OBK; 4QJ2; 4QJ6; 4QJ7; 4QJ8; 4QJ9; 4QJA; 7HVP; 8HVP

ENV_HV1A2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 5DRZ

NEF_HV1A2 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 3RBB; 3REA; 3REB; 4ORZ; 4U1K; 4U1L; 4U1M; 4U1N; 4U5W; 5XOV; 6B72; 7D7S; 8F2P

TAT_HV1A2 Protein Tat (Transactivating regulatory protein)
VIF_HV1A2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1A2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1A2 Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1A2 Protein Vpr (R ORF protein) (Viral protein R)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1BR Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1BR Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1A8G; 1A8K; 1A94; 1AAQ; 1D4S; 1D4Y; 1DAZ; 1DIF; 1FQX; 1HHP; 1HNI; 1HPO; 1HPX; 1HSG; 1HVL; 1IIQ; 1IZI; 1LZQ; 1M0B; 1MRW; 1MRX; 1MSM; 1MSN; 1NH0; 1RL8; 1SDT; 1SDU; 1SDV; 1SGU; 1SH9; 1SP5; 1U8G; 1UPJ; 1XL2; 1XL5; 1Z8C; 1ZBG; 1ZJ7; 1ZLF; 1ZPK; 1ZTZ; 2A1E; 2AZ8; 2AZ9; 2AZB; 2AZC; 2B7Z; 2BB9; 2FDE; 2HB2; 2HB4; 2HC0; 2HND; 2HNY; 2IEN; 2O4K; 2O4L; 2O4N; 2O4P; 2O4S; 2P3B; 2PK5; 2PK6; 2PQZ; 2PWC; 2PWR; 2PYM; 2PYN; 2Q63; 2Q64; 2QAK; 2QCI; 2QD6; 2QD7; 2QD8; 2QHC; 2QNN; 2QNP; 2QNQ; 2R43; 2UPJ; 2Z4O; 2ZGA; 2ZYE; 3A2O; 3BHE; 3BVA; 3BVB; 3CKT; 3DJK; 3DK1; 3FX5; 3GGU; 3H5B; 3I6O; 3I8W; 3JVW; 3JVY; 3JW2; 3KDB; 3KDC; 3KDD; 3NDU; 3NDW; 3NDX; 3NLS; 3PWM; 3PWR; 3QBF; 3QIH; 3QN8; 3QP0; 3QPJ; 3QRM; 3QRO; 3QRS; 3ST5; 3T11; 3T3C; 3TOF; 3TOG; 3TOH; 3TTP; 3U7S; 3UCB; 3UF3; 3UFN; 3UHL; 3VF5; 3VF7; 3VFB; 4DFG; 4FAF; 4FE6; 4FL8; 4FLG; 4FM6; 4GB2; 4HDB; 4HDF; 4HDP; 4HE9; 4HEG; 4HLA; 4J54; 4J55; 4J5J; 4JEC; 4LL3; 5E5K; 5YOK; 6BSH; 6P9A; 6P9B; 6UWB; 6UWC; 6VCE; 6VLM; 6VOD; 6VOE; 7DZM; 7DZN; 7M9G; 7M9H; 7M9I; 7M9J; 7M9K; 7M9L; 7M9M; 7M9N; 7M9O; 7M9P; 7M9Q; 7M9R; 7M9S; 7M9T; 7M9U; 7M9V; 7M9W; 7M9X; 7M9Z; 7MA0; 7MA1; 7MA2; 7MA3; 7MA4; 7MA5; 7MA6; 7MA7; 7MA8; 7MA9; 7MAA; 7MAB; 7MAC; 7MAD; 7MAE; 7MAF; 7MAG; 7MAH; 7MAI; 7MAJ; 7MAK; 7MAL; 7MAN; 7MAO; 7MAP; 7MAQ; 7MAR; 7MAS; 7N6T; 7N6V; 7N6X; 7TO5; 7TO6; 7UPJ; 8DCH; 8DCI; 8FUI; 8FUJ; 8VB1

ENV_HV1BR Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1ENV; 1ERF; 1FAV; 1JD8; 1P5A; 1U6U; 1U6V; 2ZZO; 3G9R; 3MNW; 3VGX; 3VTP; 5WES; 5WET; 5WEU; 6R2G

NEF_HV1BR Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 1AVV; 1AVZ; 1EFN; 4D8D; 6URI

TAT_HV1BR Protein Tat (Transactivating regulatory protein)

pdb 1JFW; 1JM4

VPU_HV1BR Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1BR Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1BR Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VIF_HV1BR Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain

Select_allDeselect_all
ENV_HV1H2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1AIK; 1DF4; 1DF5; 1DLB; 1FAV; 1G9M; 1GC1; 1GZL; 1K33; 1K34; 1MZI; 1RZJ; 2CMR; 2ME1; 2MG1; 2MG2; 2MG3; 2NY7; 2PV6; 2XRA; 3D0V; 3DNL; 3DNN; 3DNO; 3DRO; 3IDX; 3IDY; 3J70; 3MNZ; 3TYG; 3VIE; 4JPJ; 4JPK; 4YDV; 4ZTO; 5BN0; 5C0R; 5C0S; 5CIL; 5CIN; 5CMU; 5CMZ; 5CN0; 5DD0; 5GHW; 5H0N; 5HFL; 5HM1; 5IVX; 5KA5; 5KA6; 5NVP; 5NWU; 5NWW; 5TKJ; 5TKK; 5WDF; 5X08; 5YB2; 5YB3; 5YB4; 5YC0; 5Z0W; 5ZCX; 6B9K; 6BXP; 6BXQ; 6DE7; 6DLN; 6J5E; 6JQK; 6KTS; 6MQC; 6MQE; 6MQM; 6MQR; 6MQS; 6N16; 6NCP; 6NPR; 6O3G; 6O3J; 6O3L; 6O42; 6P60; 6P7H; 6P8D; 6PDR; 6PDS; 6PDU; 6PEC; 6PEF; 6PSA; 6RYF; 6SNC; 6SND; 6SNE; 6UBI; 6UCE; 6UCF; 6UJU; 6UJV; 6WWC; 7AEJ; 7EKB; 7EKK; 7FF1; 7LOH; 7LOI; 7N05; 7N08; 7R73; 7R74; 7RDW; 8B6Y; 8F3A; 8F3B; 8FYM; 8FZ2; 8G8A; 8G8C; 8G8D; 8IPG; 8TQ7; 8TQ8; 8TQ9; 8W2Y; 8W32; 8W37; 9ARN; 9ARP

POL_HV1H2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1A30; 1BV7; 1BV9; 1BVE; 1BVG; 1BWA; 1BWB; 1C0T; 1C0U; 1C1B; 1C1C; 1DMP; 1DTQ; 1DTT; 1E6J; 1EP4; 1ESK; 1EX4; 1EXQ; 1FB7; 1FK9; 1FKO; 1FKP; 1G6L; 1HIV; 1HVH; 1HVR; 1HWR; 1HXB; 1JKH; 1JLA; 1JLB; 1JLC; 1JLE; 1JLF; 1JLG; 1JLQ; 1KLM; 1LV1; 1LW0; 1LW2; 1LWC; 1LWE; 1LWF; 1NCP; 1O1W; 1ODW; 1ODY; 1QBR; 1QBS; 1QBT; 1QBU; 1REV; 1RT1; 1RT2; 1RT3; 1RT4; 1RT5; 1RT6; 1RT7; 1RTD; 1RTH; 1RTI; 1RTJ; 1S1T; 1S1U; 1S1V; 1S1W; 1S1X; 1T05; 1TAM; 1TKT; 1TKX; 1TKZ; 1TL1; 1TL3; 1VRT; 1VRU; 2HND; 2HNY; 2HNZ; 2KOD; 2NPH; 2OPP; 2OPQ; 2OPR; 2OPS; 2RF2; 2RKI; 2WHH; 2WOM; 2WON; 2YNF; 2YNG; 2YNH; 2YNI; 3AO2; 3C6T; 3C6U; 3DI6; 3DLE; 3DLG; 3DM2; 3DMJ; 3DOK; 3DOL; 3DOX; 3DRP; 3DRR; 3DRS; 3DYA; 3E01; 3FFI; 3I0R; 3I0S; 3KJV; 3KK1; 3KK2; 3KK3; 3KT2; 3KT5; 3LAK; 3LAL; 3LAM; 3LAN; 3LP0; 3LP1; 3LP2; 3M8P; 3M8Q; 3MEC; 3MED; 3MEE; 3MEG; 3N3I; 3NBP; 3PHV; 3QIN; 3QIO; 3QIP; 3T19; 3T1A; 3TAM; 4B3O; 4B3P; 4B3Q; 4I7F; 4KSE; 4KV8; 4NCG; 4Q1W; 4Q1X; 4Q1Y; 4Q5M; 4QLH; 4U1H; 4U1I; 4U1J; 4U7Q; 4U7V; 5DGU; 5DGW; 5EU7; 5HRN; 5HRP; 5HRR; 5HRS; 5IM7; 5J2M; 5J2N; 5J2P; 5J2Q; 5K14; 5KAO; 5T82; 5TC2; 5VZ6; 5XOS; 5XOT; 5YRS; 6BJ2; 6BJ3; 6BSG; 6BSH; 6BSI; 6BSJ; 6DIF; 6DIL; 6DJ1; 6DJ2; 6DJ5; 6DJ7; 6DV0; 6DV4; 6E7J; 6E9A; 6EWA; 6EX9; 6GL1; 6J1V; 6J1W; 6OR7; 6OTZ; 6P1I; 6P1X; 6P2G; 6PYL; 6SKK; 6SKM; 6SKN; 6SLQ; 6SLU; 6SMU; 6UIR; 6UIS; 6UIT; 6UJX; 6UJY; 6UJZ; 6UK0; 6VPZ; 6VQ2; 6VQD; 6VQE; 6VQY; 6VQZ; 6WAZ; 6WB1; 6WPF; 6WPH; 6WPJ; 7DOZ; 7DPQ; 7DT9; 7R7V; 7R7X; 7R80; 7SLR; 7SLS; 7XIU; 7XJ4; 7XJ5; 7XJ7; 8ERX; 8ESX; 8ESY; 8F0F; 8F5A; 8F7M; 8FCC; 8FCD; 8FCE; 8JYH; 8JYI; 8JYJ; 8TCJ; 8TCK; 8TCL; 8TCM

GAG_HV1H2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1TSQ; 1TSU; 5FJB; 5I1R; 5INC; 5IND; 5NME; 5NMF; 5NMG; 5NMH; 5NMK; 6CPL; 6CPN; 6CPO; 6CQJ; 6CQL; 6CQN; 6CQQ; 6CQR; 6EC2; 6ECN; 6ECO; 6N3J; 6N3U; 6ZDJ; 7ASH; 7ASL; 7WJ2; 9CWV; 9D6C; 9DWD

NEF_HV1H2 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 3RL2; 4NEE; 4WU5; 4WU7; 5HGA; 5HGB; 5HGD; 5HGH; 7K80; 7K81; 7YG3; 8GVB; 8GVG; 8GVI; 9BL9; 9BLA

TAT_HV1H2 Protein Tat (Transactivating regulatory protein)

pdb 3MI9; 3MIA; 4OR5; 5V61; 6CYT; 6MCE; 6MCF

REV_HV1H2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

pdb 6HIP; 7JYA

VPU_HV1H2 Protein Vpu (U ORF protein) (Viral protein U)

pdb 2N29

VIF_HV1H2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]

pdb 8CX0; 8CX1; 8CX2

VPR_HV1H2 Protein Vpr (R ORF protein) (Viral protein R)

pdb 4U1S

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain

Select_allDeselect_all
NEF_HV1MN Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1MN Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1ACY; 1AI1; 1F58; 1GGI; 1K5M; 1NAK; 1NIZ; 1NJ0; 1Q1J; 2B0S; 2QSC; 3E6H; 3GO1; 3MLW; 3MLX; 3UJI; 4M1D; 4XAW; 4XBE; 4XC1; 4XC3; 4XCF; 4XMK; 5KD4; 5KD7; 5T7G; 6DB6; 6DB7; 6MNS; 6SH9

GAG_HV1MN Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1AAF

TAT_HV1MN Protein Tat (Transactivating regulatory protein)
POL_HV1MN Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1AAF

VIF_HV1MN Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1MN Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1MN Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1MN Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1) reference strain

Select_allDeselect_all
ENV_HV1RH Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1RH Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
GAG_HV1RH Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
TAT_HV1RH Protein Tat (Transactivating regulatory protein)
POL_HV1RH Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 2FXE

VIF_HV1RH Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1RH Protein Vpr (R ORF protein) (Viral protein R)

pdb 1FI0

VPU_HV1RH Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1RH Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1B9 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1B9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1B9 Protein Tat (Transactivating regulatory protein)
ENV_HV1B9 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 4R4H; 5U3K; 5U3L; 5U3M; 5U3N; 5U3O; 6X58

NEF_HV1B9 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VPR_HV1B9 Protein Vpr (R ORF protein) (Viral protein R)

pdb 1CEU; 1ESX; 1M8L; 1VPC; 1X9V; 5B56

VIF_HV1B9 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1B9 Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1B9 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV192 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV192 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 2R5P; 2R5Q; 2R8N

TAT_HV192 Protein Tat (Transactivating regulatory protein)
ENV_HV192 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV192 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV192 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV192 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV192 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV192 Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1ET Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1ET Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 6T6I; 6T6J

ENV_HV1ET Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1ET Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1ET Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
TAT_HV1ET Protein Tat (Transactivating regulatory protein)
VPU_HV1ET Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1ET Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1ET Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain

Select_allDeselect_all
ENV_HV1EL Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
POL_HV1EL Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV1EL Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
NEF_HV1EL Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
TAT_HV1EL Protein Tat (Transactivating regulatory protein)
VIF_HV1EL Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1EL Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1EL Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1EL Protein Vpr (R ORF protein) (Viral protein R)

9 entries

Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain

Select_allDeselect_all
TAT_HV193 Protein Tat (Transactivating regulatory protein)
POL_HV193 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV193 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
ENV_HV193 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV193 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV193 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV193 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV193 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV193 Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain

Select_allDeselect_all
NEF_HV1VI Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1VI Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
TAT_HV1VI Protein Tat (Transactivating regulatory protein)
POL_HV1VI Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV1VI Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV1VI Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1VI Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1VI Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1VI Protein Vpr (R ORF protein) (Viral protein R)

9 entries

Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain

Select_allDeselect_all
TAT_HV190 Protein Tat (Transactivating regulatory protein)
ENV_HV190 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV190 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
GAG_HV190 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV190 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
VIF_HV190 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV190 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV190 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV190 Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1YF Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1YF Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 7R7W; 7R7Y

TAT_HV1YF Protein Tat (Transactivating regulatory protein)
ENV_HV1YF Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1YF Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1YF Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1YF Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1YF Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1YF Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain

Select_allDeselect_all
TAT_HV1AN Protein Tat (Transactivating regulatory protein)
GAG_HV1AN Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1AN Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
ENV_HV1AN Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1AN Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 3WLB

VIF_HV1AN Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1AN Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1AN Protein Vpr (R ORF protein) (Viral protein R)
VPU_HV1AN Protein Vpu (U ORF protein) (Viral protein U)

6 entries

Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain

Select_allDeselect_all
GAG_HV1U4 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1NCP

TAT_HV1U4 Protein Tat (Transactivating regulatory protein)
POL_HV1U4 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1E27; 1NCP; 3LZS; 3LZU

NEF_HV1U4 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1U4 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1U4 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)

Select_allDeselect_all
GAG_HV1B1 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 2BUO; 5KP9; 6BHR

POL_HV1B1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1A9M; 1AJV; 1AJX; 1AXA; 1BQM; 1BQN; 1D4H; 1D4I; 1D4J; 1DLO; 1DW6; 1EBK; 1EBW; 1EBY; 1EBZ; 1EC0; 1EC1; 1EC2; 1EC3; 1EET; 1G35; 1GNM; 1GNN; 1GNO; 1HAR; 1HBV; 1HEF; 1HEG; 1HIH; 1HMV; 1HNI; 1HNV; 1HOS; 1HPS; 1HPZ; 1HQE; 1HQU; 1HRH; 1HTE; 1HTF; 1HTG; 1HVI; 1HVK; 1HVU; 1HYS; 1IKV; 1IKW; 1IKX; 1IKY; 1J5O; 1KJH; 1MER; 1MES; 1MET; 1MEU; 1N5Y; 1N6Q; 1NPA; 1NPV; 1NPW; 1QE1; 1QMC; 1R0A; 1RDH; 1RTD; 1S6P; 1S6Q; 1S9E; 1S9G; 1SBG; 1SUQ; 1SV5; 1T03; 1T05; 1T7K; 1TV6; 1TVR; 1UWB; 1W5V; 1W5W; 1W5X; 1W5Y; 1YT9; 1ZP8; 1ZPA; 1ZSF; 1ZSR; 2AQU; 2B5J; 2B6A; 2BAN; 2BBB; 2BE2; 2EXF; 2G69; 2HB3; 2HMI; 2HNZ; 2HS1; 2HS2; 2I4D; 2I4U; 2I4V; 2I4W; 2I4X; 2I5J; 2IAJ; 2IC3; 2IDW; 2IEO; 2JZW; 2L45; 2L46; 2L4L; 2UXZ; 2UY0; 2VG5; 2VG6; 2VG7; 2X4U; 2YKM; 2YKN; 2ZD1; 2ZE2; 3AVI; 3BGR; 3DLK; 3GGA; 3GGV; 3GGX; 3HVT; 3IG1; 3IRX; 3IS9; 3ISN; 3ITH; 3JSM; 3JYT; 3K2P; 3K4V; 3KLE; 3KLF; 3KLG; 3KLH; 3KLI; 3NDT; 3NU3; 3NU4; 3NU5; 3NU6; 3NU9; 3NUJ; 3NUO; 3OK9; 3PSU; 3QAA; 3QLH; 3QO9; 3TKG; 3TKW; 3TL9; 3TLH; 3V4I; 3V6D; 3V81; 3ZPS; 3ZPT; 3ZPU; 4COE; 4CP7; 4CPQ; 4CPR; 4CPS; 4CPT; 4CPU; 4CPW; 4CPX; 4DG1; 4G1Q; 4G8G; 4G8I; 4G9D; 4G9F; 4H4M; 4H4O; 4I2P; 4I2Q; 4ICL; 4ID5; 4IDK; 4IFV; 4IFY; 4IG0; 4IG3; 4KFB; 4KKO; 4KO0; 4LSL; 4LSN; 4MFB; 4O44; 4O4G; 4OJR; 4PQU; 4PUO; 4PWD; 4Q0B; 4QAG; 4R5P; 4RW4; 4RW6; 4RW7; 4RW8; 4RW9; 4U8W; 4WE1; 4YE3; 4YHQ; 4ZIP; 4ZLS; 5AGZ; 5AH6; 5AH7; 5AH8; 5AH9; 5AHA; 5AHB; 5AHC; 5BRY; 5BS4; 5C24; 5C25; 5C42; 5CYM; 5CYQ; 5D3G; 5FDL; 5HBM; 5HLF; 5HP1; 5HRO; 5I3U; 5I42; 5J1E; 5JFP; 5JFU; 5JG1; 5OI2; 5OI3; 5OI5; 5OI8; 5OIA; 5T6Z; 5T70; 5TER; 5TUQ; 5TW3; 5TXL; 5TXM; 5TXN; 5TXO; 5TXP; 5UFZ; 5ULT; 5UOV; 5UPZ; 5UV5; 5V5L; 5V5M; 5VQQ; 5VQR; 5VQS; 5VQT; 5VQU; 5VQV; 5VQW; 5VQX; 5VQY; 5VQZ; 5W5W; 5YOJ; 6AMO; 6AN2; 6AN8; 6ANQ; 6AOC; 6ASW; 6AVM; 6AVT; 6B19; 6BZ2; 6C0J; 6C0K; 6C0L; 6C0N; 6C0O; 6C0P; 6C0R; 6C8X; 6C8Y; 6CGF; 6D0D; 6D0E; 6DTW; 6DTX; 6DUF; 6DUG; 6DUH; 6ECL; 6ELI; 6HAK; 6KMP; 6O48; 6O9E; 6OE3; 6OUN; 6PRF; 6UL5; 6VUG; 6WAZ; 6WB0; 6WB1; 6WB2; 6X47; 6X49; 6X4A; 6X4B; 6X4C; 6X4D; 6X4E; 6X4F; 7AHX; 7AID; 7AIF; 7AIG; 7AII; 7AIJ; 7KJV; 7KJW; 7KJX; 7KRC; 7KRD; 7KRE; 7KRF; 7KWU; 7LPW; 7LPX; 7LQU; 7LRI; 7LRM; 7LRX; 7LRY; 7LSK; 7OT6; 7OTA; 7OTK; 7OTN; 7OTX; 7OTZ; 7OUT; 7OXQ; 7OZ2; 7OZ5; 7OZW; 7P15; 7SEP; 7SIF; 7SIG; 7SIH; 7SJX; 7SNL; 7SNN; 7SNP; 7SNQ; 7SNZ; 7SO1; 7SO2; 7SO3; 7SO4; 7SO6; 7TAZ; 7U5Z; 7Z24; 7Z29; 7Z2D; 7Z2E; 7Z2G; 7Z2H; 8DX2; 8DX3; 8DX8; 8DXB; 8DXE; 8DXG; 8DXH; 8DXI; 8DXJ; 8DXK; 8DXL; 8DXM; 8FE8; 8FFX; 8STP; 8STQ; 8STR; 8STS; 8STT; 8STU; 8STV; 8U69; 8U6A; 8U6B; 8U6C; 8U6D; 8U6E; 8U6F; 8U6G; 8U6H; 8U6I; 8U6J; 8U6K; 8U6L; 8U6M; 8U6N; 8U6O; 8U6P; 8U6Q; 8U6R; 8U6S; 8U6T; 8V8F; 8VB6; 8VB7; 8VB8; 8VB9; 8VBC; 8VBD; 8VBE; 8VBF; 8VBG; 8VBH; 8VBI

ENV_HV1B1 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2ARI; 3VGY; 3VH7; 3VU5; 3VU6; 3W19; 6ME1

NEF_HV1B1 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 1ZEC; 3TB8

REV_HV1B1 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

pdb 2X7L; 5DHV; 5DHX; 5DHY; 5DHZ; 6BSY; 6CF2; 7U0F

TAT_HV1B1 Protein Tat (Transactivating regulatory protein)

pdb 5L1Z

VPU_HV1B1 Protein Vpu (U ORF protein) (Viral protein U)

pdb 2JPX; 2N28

VIF_HV1B1 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1B1 Protein Vpr (R ORF protein) (Viral protein R)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)

Select_allDeselect_all
NEF_HV1JR Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1JR Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1CE4; 2ESX; 2ESZ; 4R2G; 5V6L; 5V6M

GAG_HV1JR Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1JR Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1KJ4; 1KJ7; 1KJF

TAT_HV1JR Protein Tat (Transactivating regulatory protein)
VIF_HV1JR Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1JR Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1JR Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1JR Protein Vpu (U ORF protein) (Viral protein U)

9 entries

Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)

Select_allDeselect_all
NEF_HV1Y2 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1Y2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1G9N; 1RZK; 1YYL; 1YYM; 2I5Y; 2I60; 2NY7; 2QAD; 3HI1; 3TGQ; 4DVR; 4JO3; 4JZW; 4JZZ; 4K0A; 4KA2; 4LAJ; 4R4F; 4RQS; 4RWY; 5A7X; 5A8H

GAG_HV1Y2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1F6U; 1MFS; 2R05; 8D3B

POL_HV1Y2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1F6U; 1K6C; 1K6P; 1K6T; 1K6V; 1MFS; 1T7I; 1T7J; 1WJA; 1WJC; 2JO0; 2L6E; 3OQ7; 3OQA; 3OQD; 3OTS; 3OTY; 3OU1; 3OU3; 3OU4; 3OUA; 3OUB; 3OUC; 3OUD; 3PJ6; 3U7S; 4A6B; 4A6C

TAT_HV1Y2 Protein Tat (Transactivating regulatory protein)
VIF_HV1Y2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1Y2 Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1Y2 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1Y2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

9 entries

Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)

Select_allDeselect_all
NEF_HV1YB Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1YB Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
TAT_HV1YB Protein Tat (Transactivating regulatory protein)
GAG_HV1YB Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1YB Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 2HJL

VIF_HV1YB Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1YB Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1YB Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1YB Protein Vpr (R ORF protein) (Viral protein R)

9 entries

Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)

Select_allDeselect_all
TAT_HV1MV Protein Tat (Transactivating regulatory protein)
GAG_HV1MV Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 7T12

POL_HV1MV Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
ENV_HV1MV Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1MV Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1MV Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1MV Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1MV Protein Vpr (R ORF protein) (Viral protein R)
VPU_HV1MV Protein Vpu (U ORF protein) (Viral protein U)

8 entries

Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)

Select_allDeselect_all
NEF_HV1OY Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1OY Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
GAG_HV1OY Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1OY Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1OY Protein Tat (Transactivating regulatory protein)
VIF_HV1OY Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1OY Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1OY Protein Vpr (R ORF protein) (Viral protein R)

8 entries

Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)

Select_allDeselect_all
ENV_HV1ND Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
GAG_HV1ND Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
NEF_HV1ND Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
POL_HV1ND Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1ND Protein Tat (Transactivating regulatory protein)
VIF_HV1ND Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPU_HV1ND Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1ND Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)

Select_allDeselect_all
ENV_HV1Z2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 3UIA

GAG_HV1Z2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1SJE; 1SJH; 3D3T

POL_HV1Z2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1E28; 1HXW; 1P7Q; 1PRO; 1Q94; 1VIJ; 1VIK; 2WKZ; 2WL0; 2XYE; 2XYF; 3KF0; 3KFN; 3KFP; 3KFR; 3KFS; 3W39; 4DQB; 4DQC; 4DQE; 4DQF; 4DQG; 4DQH; 4E43; 4EJ8; 4EJD; 4EJK; 4EJL; 4K4P; 4K4Q; 4K4R

TAT_HV1Z2 Protein Tat (Transactivating regulatory protein)

pdb 1TAC; 1TBC; 1TIV; 2BGN; 2BGR; 8CCW; 8CCZ

VIF_HV1Z2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1Z2 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1Z2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1Z2 Protein Vpu (U ORF protein) (Viral protein U)

8 entries

Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)

Select_allDeselect_all
TAT_HV1MP Protein Tat (Transactivating regulatory protein)
NEF_HV1MP Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1MP Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
POL_HV1MP Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV1MP Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV1MP Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1MP Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1MP Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)

Select_allDeselect_all
TAT_HV1M2 Protein Tat (Transactivating regulatory protein)
NEF_HV1M2 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1M2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
POL_HV1M2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV1M2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV1M2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1M2 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1M2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)

Select_allDeselect_all
POL_HV19N Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV19N Protein Tat (Transactivating regulatory protein)
ENV_HV19N Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV19N Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
GAG_HV19N Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV19N Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV19N Protein Vpr (R ORF protein) (Viral protein R)
REV_HV19N Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)

Select_allDeselect_all
NEF_HV1V9 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1V9 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 3UJJ; 7Z7C; 8AED

TAT_HV1V9 Protein Tat (Transactivating regulatory protein)
POL_HV1V9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV1V9 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV1V9 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1V9 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPR_HV1V9 Protein Vpr (R ORF protein) (Viral protein R)

8 entries

Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)

Select_allDeselect_all
GAG_HV1S9 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 2R02

POL_HV1S9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1S9 Protein Tat (Transactivating regulatory protein)
ENV_HV1S9 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1S9 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1S9 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1S9 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1S9 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)

Select_allDeselect_all
GAG_HV1S2 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1S2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1S2 Protein Tat (Transactivating regulatory protein)
ENV_HV1S2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
NEF_HV1S2 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1S2 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1S2 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1S2 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)

Select_allDeselect_all
TAT_HV196 Protein Tat (Transactivating regulatory protein)
NEF_HV196 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV196 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
POL_HV196 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV196 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV196 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV196 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV196 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

8 entries

Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)

Select_allDeselect_all
TAT_HV197 Protein Tat (Transactivating regulatory protein)
NEF_HV197 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV197 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
POL_HV197 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
GAG_HV197 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV197 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV197 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV197 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

7 entries

Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)

Select_allDeselect_all
POL_HV1LW Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 3LP3; 3TH9; 3VFA; 4I8W; 4I8Z; 4MC1; 4MC2; 4MC6; 4MC9; 4NYF; 4QGI; 5K14; 6Y9V; 6Y9W; 6Y9X; 6Y9Y; 6Y9Z; 9JA0

GAG_HV1LW Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1HVN; 1HVO; 1U57; 2ZNF

ENV_HV1LW Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2X7R; 2Z2T; 3AHA; 3CP1; 3CYO; 3GWO; 3H00; 3H01; 4I48; 5HFM; 6X58

NEF_HV1LW Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 2NEF

VPU_HV1LW Protein Vpu (U ORF protein) (Viral protein U)

pdb 1PI7; 1PI8; 1PJE; 2GOF; 2GOH

VIF_HV1LW Truncated virion infectivity factor (Vif) (SOR protein) [Cleaved into: Truncated p17]
REV_HV1LW Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

7 entries

Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)

Select_allDeselect_all
GAG_HV1SE Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
POL_HV1SE Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...
TAT_HV1SE Protein Tat (Transactivating regulatory protein)
NEF_HV1SE Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VIF_HV1SE Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1SE Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1SE Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

6 entries

Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)

Select_allDeselect_all
ENV_HV1H3 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1JAU; 1JAV; 8ELI

NEF_HV1H3 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
TAT_HV1H3 Protein Tat (Transactivating regulatory protein)

pdb 4OGR

REV_HV1H3 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

pdb 3LPH; 4PMI

VPU_HV1H3 Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1H3 Protein Vpr (R ORF protein) (Viral protein R)

6 entries

Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)

Select_allDeselect_all
NEF_HV1SC Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1SC Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2M8M; 2M8O; 3E6F

TAT_HV1SC Protein Tat (Transactivating regulatory protein)
REV_HV1SC Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VPU_HV1SC Protein Vpu (U ORF protein) (Viral protein U)
VPR_HV1SC Protein Vpr (R ORF protein) (Viral protein R)

5 entries

Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)

Select_allDeselect_all
ENV_HV1C4 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...
GAG_HV1C4 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
TAT_HV1C4 Protein Tat (Transactivating regulatory protein)

pdb 9DE5

VPU_HV1C4 Protein Vpu (U ORF protein) (Viral protein U)
REV_HV1C4 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

5 entries

Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)

Select_allDeselect_all
GAG_HV1N5 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...

pdb 1GWP; 2C55; 2MGU; 3GV2; 4U0A; 4U0B; 4U0C; 4U0D; 4U0E; 4U0F; 4XFX; 4XFY; 4XFZ; 4XRO; 4XRQ; 5HGL; 5HGM; 5HGN; 5HGO; 5HGP; 5IRT; 5JPA; 5L93; 5O2U; 5TSV; 5TSX; 5UPW; 5W4O; 5W4P; 5W4Q; 6AXR; 6AXS; 6AXT; 6AXV; 6AXW; 6AXX; 6AXY; 6AY9; 6AYA; 6B2G; 6B2H; 6B2I; 6B2J; 6B2K; 6BHS; 6BHT; 6ECN; 6H09; 6MQA; 6MQO; 6MQP; 6OBH; 6OMT; 6PU1; 6R6Q; 6RWG; 6V2F; 6VKV; 6VWS; 6WAP; 6X63; 7E1J; 7JXR; 7JXS; 7M9F; 7MKC; 7MN0; 7N9U; 7N9V; 7OVQ; 7OVR; 7P3O; 7QDF; 7R7P; 7R7Q; 7RAO; 7RAR; 7RHM; 7RHN; 7RJ2; 7RJ4; 7T13; 7TBP; 7URN; 7URT; 8CKV; 8CKW; 8CKX; 8CKY; 8CKZ; 8CL0; 8CL1; 8CL2; 8CL3; 8CL4; 8EEP; 8EET; 8EJL; 8FIU; 8G6K; 8G6L; 8G6M; 8G6N; 8G6O; 8GDV; 8QUB; 8QUH; 8QUI; 8QUJ; 8QUK; 8QUL; 8QUW; 8QUX; 8QUY; 8QV1; 8QV4; 8QV9; 8QVA; 8TY6; 9D6D; 9D6E; 9D88; 9H1P

POL_HV1N5 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1A43; 1A8O; 1AFV; 1AK4; 1AUM; 1B92; 1B9D; 1B9F; 1BAJ; 1BHL; 1BI4; 1BIS; 1BIU; 1BIZ; 1BL3; 1GWP; 1HIW; 1HYV; 1HYZ; 1ITG; 1K6Y; 1M9D; 1QS4; 1UPH; 1WJB; 1WJD; 2B4J; 2GOL; 2GON; 2H3F; 2H3I; 2H3Q; 2H3V; 2H3Z; 2HMX; 2HVP; 2ITG; 2JPR; 2JYG; 2JYL; 2LF4; 2LYA; 2LYB; 2M3Z; 2M8L; 2M8N; 2M8P; 2ONT; 2PWM; 2PWO; 2PXR; 2X2D; 2XDE; 2XV6; 2XXM; 3AV9; 3AVA; 3AVB; 3AVC; 3AVF; 3AVG; 3AVH; 3AVJ; 3AVK; 3AVL; 3AVM; 3AVN; 3DIK; 3DPH; 3DS0; 3DS1; 3DS2; 3DS3; 3DS4; 3DS5; 3DTJ; 3GV2; 3H47; 3H4E; 3L3U; 3L3V; 3LPT; 3LPU; 3LRY; 3MGE; 3NF6; 3NF7; 3NF8; 3NF9; 3NFA; 3P05; 3P0A; 3S85; 3WNE; 3WNF; 3WNG; 3WNH; 3ZCM; 3ZSO; 3ZSQ; 3ZSR; 3ZSV; 3ZSW; 3ZSX; 3ZSY; 3ZSZ; 3ZT0; 3ZT1; 3ZT2; 3ZT3; 3ZT4; 4AH9; 4AHR; 4AHS; 4AHT; 4AHU; 4AHV; 4CE9; 4CEA; 4CEB; 4CEC; 4CED; 4CEE; 4CEF; 4CEO; 4CEQ; 4CER; 4CES; 4CEZ; 4CF0; 4CF1; 4CF2; 4CF8; 4CF9; 4CFA; 4CFB; 4CFC; 4CFD; 4CGD; 4CGF; 4CGG; 4CGH; 4CGI; 4CGJ; 4CHN; 4CHO; 4CHP; 4CHQ; 4CHY; 4CHZ; 4CIE; 4CIF; 4CIG; 4CJ3; 4CJ4; 4CJ5; 4CJE; 4CJF; 4CJK; 4CJL; 4CJP; 4CJQ; 4CJR; 4CJS; 4CJT; 4CJU; 4CJV; 4CJW; 4CK1; 4CK2; 4CK3; 4COC; 4COP; 4DGA; 4DGE; 4DMN; 4E1M; 4E1N; 4E91; 4E92; 4GVM; 4GW6; 4ID1; 4IPY; 4JLH; 4JMU; 4LH4; 4LH5; 4LQW; 4NX4; 4O0J; 4O55; 4O5B; 4OVL; 4PHV; 4QNB; 4WYM; 4Y1C; 4Y1D; 4ZHR; 5HVP; 5JL4; 5KGW; 5KGX; 5KRS; 5KRT; 5TEO; 5U1C; 5VCK; 5VEA; 5VJ3; 5XN0; 5XN1; 5XN2; 6ES8; 6IK9; 6IKA; 6JCF; 6JCG; 6KDJ; 6KDK; 6KDM; 6KDN; 6KDO; 6LMI; 6LMQ; 6MCR; 6MCS; 6OOS; 6OOT; 6OOU; 6OPW; 6OPY; 6OPZ; 6OXO; 6OXP; 6OXQ; 6OXR; 6OXS; 6OXT; 6OXU; 6OXV; 6OXW; 6OXX; 6OXY; 6OXZ; 6OY0; 6OY1; 6OY2; 6OYD; 6OYR; 6PJB; 6PJC; 6PJD; 6PJE; 6PJF; 6PJG; 6PJH; 6PJI; 6PJK; 6PJL; 6PJM; 6PJN; 6PJO; 6PUT; 6PUW; 6PUY; 6PUZ; 6T6E; 6U8Q; 6UM8; 6V3K; 6VDK; 6VQS; 6VRG; 6VX2; 6W0U; 6W42; 6W6T; 7D83; 7DBM; 7DBN; 7KE0; 7L1P; 7L23; 7LDY; 7LDZ; 7LE0; 7LE1; 7LE2; 7LE3; 7LE4; 7LE5; 7LE6; 7LE7; 7LE8; 7LE9; 7LEA; 7LEB; 7LEC; 7LED; 7LEE; 7LEF; 7LEG; 7LEH; 7LEI; 7LQP; 7RQ0; 7SIA; 7T9H; 7T9O; 7U2U; 7UE1; 7UOQ; 7WBS; 7WCE; 7WCQ; 7YF6; 7ZUD; 8A1P; 8A1Q; 8BUV; 8BV2; 8CBR; 8CBS; 8CBT; 8CBU; 8CBV; 8CT5; 8CT7; 8D3S; 8F22; 8FN7; 8FND; 8FNG; 8FNH; 8FNJ; 8FNL; 8FNM; 8FNN; 8FNO; 8FNP; 8FNQ; 8S9Q; 8T52; 8T5A; 8TOV; 8TQP; 8V23; 8W09; 8W2R; 8W34; 8WF7; 8X1Z; 8X20; 8X21; 8X22; 8ZH4; 8ZHA; 9EK1; 9EK2; 9EK3; 9HVP

VIF_HV1N5 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]

pdb 2MA9; 3DCG; 4N9F; 6NIL; 8E40; 8FVI; 8FVJ; 8H0I; 8J62; 8SZK

VPR_HV1N5 Protein Vpr (R ORF protein) (Viral protein R)

pdb 1BDE; 1DSJ; 1DSK; 1KZS; 1KZT; 1KZV; 5JK7; 6XQI; 6XQJ; 7V7C

ENV_HV1N5 Truncated surface protein (SU) (Glycoprotein 120) (gp120)

pdb 3MLR; 6DB5

5 entries

Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)

Select_allDeselect_all
NEF_HV112 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 1QA4; 1QA5; 1ZEC

TAT_HV112 Protein Tat (Transactivating regulatory protein)

pdb 5SVZ

REV_HV112 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)
VIF_HV112 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV112 Protein Vpr (R ORF protein) (Viral protein R)

5 entries

Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)

Select_allDeselect_all
NEF_HV1S1 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1S1 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 8FAD

TAT_HV1S1 Protein Tat (Transactivating regulatory protein)
VPU_HV1S1 Protein Vpu (U ORF protein) (Viral protein U)

pdb 1VPU; 2K7Y; 4P6Z

REV_HV1S1 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

5 entries

Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)

Select_allDeselect_all
NEF_HV1S3 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1S3 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1MEQ

TAT_HV1S3 Protein Tat (Transactivating regulatory protein)
VPR_HV1S3 Protein Vpr (R ORF protein) (Viral protein R)
REV_HV1S3 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

5 entries

Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)

Select_allDeselect_all
ENV_HV1Z6 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1TJH; 1TJI; 3F4Y; 3F50; 3G7A; 3MOA; 3MOB; 3MOD; 4I2L

NEF_HV1Z6 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]

pdb 1QVO

TAT_HV1Z6 Protein Tat (Transactivating regulatory protein)
VIF_HV1Z6 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
REV_HV1Z6 Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

pdb 1RPV

4 entries

Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)

Select_allDeselect_all
POL_HV1B5 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1BDL; 1BDQ; 1BDR; 1FEJ; 1FF0; 1FFF; 1FFI; 1FG6; 1FG8; 1FGC; 1G2K; 1HPV; 1HVJ; 1HVS; 1K1T; 1K1U; 1K2B; 1K2C; 1ODX; 1Q9P; 1TCX; 1WJE; 1WJF; 2AOC; 2AOD; 2AOE; 2AOF; 2AOG; 2AOH; 2AOI; 2AOJ; 2AVM; 2AVO; 2AVQ; 2AVS; 2AVV; 2BPV; 2BPW; 2BPX; 2BPY; 2BPZ; 2F80; 2F81; 2F8G; 2NMY; 2NMZ; 2NNK; 2NNP; 2R38; 2R3T; 2R3W; 2Z54; 3B7V; 3B80; 3BC4; 3BGB; 3BGC; 3CYW; 3CYX; 3D1X; 3D1Y; 3D1Z; 3D20; 3OXC; 6B36; 6B38; 6B3C; 6B3F; 6B3G; 6B3H

GAG_HV1B5 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VIF_HV1B5 Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]
VPR_HV1B5 Protein Vpr (R ORF protein) (Viral protein R)

3 entries

Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)

Select_allDeselect_all
ENV_HV1B8 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1DDH; 1HHG; 1QO3; 1SZT; 6TVU

NEF_HV1B8 Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
VPU_HV1B8 Protein Vpu (U ORF protein) (Viral protein U)

3 entries

Human immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)

Select_allDeselect_all
NEF_HV1BN Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1BN Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1IM7; 1J8N; 1J8Z; 1J9V; 1JAA; 1JAR; 1JC8; 1JCP

VPU_HV1BN Protein Vpu (U ORF protein) (Viral protein U)

3 entries

Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)

Select_allDeselect_all
ENV_HV1J3 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 8TDX

GAG_HV1J3 Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer ...
VPU_HV1J3 Protein Vpu (U ORF protein) (Viral protein U)

2 entries

Human immunodeficiency virus type 1 group M subtype A (isolate Z321) (HIV-1)

Select_allDeselect_all
NEF_HV1ZH Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
ENV_HV1ZH Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

1 entry

Human immunodeficiency virus type 1 (HIV-1)

VPU_HV1 Protein Vpu (U ORF protein) (Viral protein U)

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate KB-1/ETR) (HIV-1)

ENV_HV1KB Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate MFA) (HIV-1)

ENV_HV1MF Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2NXZ; 2NY0; 2NY2; 2NY4; 2NY5; 2PJV; 3ECB

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate N1T-A) (HIV-1)

VIF_HV1NA Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate WMJ1) (HIV-1)

ENV_HV1W1 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 1LB0; 1LCX

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate WMJ22) (HIV-1)

ENV_HV1W2 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

pdb 2FX7; 2FX8; 2FX9; 4WY7; 6VPX

1 entry

Human immunodeficiency virus type 1 group M subtype D (isolate Z84) (HIV-1)

ENV_HV1Z8 Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) ...

1 entry

Human immunodeficiency virus type 1 group M subtype U (isolate Z3) (HIV-1)

ENV_HV1Z3 Truncated surface protein (SU) (Glycoprotein 120) (gp120)