Phi29-like viruses

Molecular biology

VIRION

Nonenveloped, head-tail structure. Head is about 54 nm in diameter. The tail is non-contractile and has a collar with 12 appendages. The capsid is icosahedral with a T=3 symmetry.

GENOME

Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its tail fibers.
  2. Injection: viral DNA is injected in host cell periplasm
  3. Transcription and traduction of early genes
  4. Replication of genomic DNA
  5. Transcription and traduction of late genes
  6. Assembly of new virions in host cell cytoplasm
  7. Mature virions are released from the cell by lysis
DB LINKS Nucleotide DB: NCBI
Protein DB: UniProtKB
TAXONOMY Group I: dsDNA viruses
Order: Caudovirales
Family: Podoviridae
Subfamily: Picovirinae
Genus: Phi29-like viruses
SPECIES
Type: Bacillus phage phi29 (phi29)
REFERENCE STRAINS Bacillus phage phi29
Sequence | Genome | Proteome
HOST Bacteria

Epidemiology

GEOGRAPHY Worldwide
TRANSMISSION Passive diffusion through medium
ANTIVIRAL DRUGS

Matching UniProtKB/Swiss-Prot entries

78 entries grouped by protein

All proteins are shown (view only 26 complete proteome entries)

DNA polymerase (EC 2.7.7.7) (Early protein GP2)

Select_all Deselect_all  
DPOL_BPB03Bacillus phage B103 (Bacteriophage B103)
DPOL_BPM2Bacillus phage M2 (Bacteriophage M2)

DNA polymerase (EC 2.7.7.7)

DPOL_BPPZABacillus phage PZA (Bacteriophage PZA)
DPOL_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 1XHX  1XHZ  1XI1  2EX3  2PY5  2PYJ  2PYL  2PZS 

Major head protein (Late protein Gp8)

Select_all Deselect_all  
HEAD_BPB03Bacillus phage B103 (Bacteriophage B103)
HEAD_BPGA1Bacillus phage GA-1 (Bacteriophage GA-1)

Major head protein

HEAD_BPPZABacillus phage PZA (Bacteriophage PZA)
HEAD_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Lysozyme (EC 3.2.1.17) (Endolysin) (Lysis protein) (Morphogenesis protein 2) (Muramidase)

Select_all Deselect_all  
LYS_BPB03Bacillus phage B103 (Bacteriophage B103)
LYS_BPPZABacillus phage PZA (Bacteriophage PZA)

Lysozyme (EC 3.2.1.17) (Endolysin) (Late protein gp15) (Lysis protein) (Muramidase)

LYS_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Single-strand-binding protein (SSB) (Early protein GP5)

Select_all Deselect_all  
SSB_BPB03Bacillus phage B103 (Bacteriophage B103)
SSB_BPPZABacillus phage PZA (Bacteriophage PZA)
SSB_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

DNA terminal protein (Protein GP3)

Select_all Deselect_all  
TERM_BPB03Bacillus phage B103 (Bacteriophage B103)
TERM_BPNFBacillus phage Nf (Bacteriophage Nf)
TERM_BPPZABacillus phage PZA (Bacteriophage PZA)
TERM_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

DNA terminal protein (Protein Gp3)

pdb 2EX3 

Early protein GP1


VG1_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Upper collar protein (Connector protein) (Late protein GP10)

Select_all Deselect_all  
VG10_BPB03Bacillus phage B103 (Bacteriophage B103)
VG10_BPPZABacillus phage PZA (Bacteriophage PZA)
VG10_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 1FOU  1H5W  1IJG  1JNB  1L4P  1VRI  1VRJ  1YWE 

Lower collar protein (Late protein GP11)

Select_all Deselect_all  
VG11_BPB03Bacillus phage B103 (Bacteriophage B103)
VG11_BPPZABacillus phage PZA (Bacteriophage PZA)
VG11_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Pre-neck appendage protein (Late protein GP12)

Select_all Deselect_all  
VG12_BPB03Bacillus phage B103 (Bacteriophage B103)
VG12_BPPZABacillus phage PZA (Bacteriophage PZA)
VG12_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 3GQ7  3GQ8  3GQ9  3GQA  3GQH  3GQK  3SUC 

Morphogenesis protein 1 (Late protein GP13)

Select_all Deselect_all  
VG13_BPB03Bacillus phage B103 (Bacteriophage B103)
VG13_BPPZABacillus phage PZA (Bacteriophage PZA)
VG13_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 3CSQ  3CSR  3CSZ  3CT0  3CT1  3CT5 

Lysis protein (Late protein GP14)

Select_all Deselect_all  
VG14_BPB03Bacillus phage B103 (Bacteriophage B103)
VG14_BPPZABacillus phage PZA (Bacteriophage PZA)
VG14_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Encapsidation protein (Late protein GP16)

Select_all Deselect_all  
VG16_BPB03Bacillus phage B103 (Bacteriophage B103)
VG16_BPPZABacillus phage PZA (Bacteriophage PZA)
VG16_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP16.5

Select_all Deselect_all  
VG165_BPPZABacillus phage PZA (Bacteriophage PZA)
VG165_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG165_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP16.6

Select_all Deselect_all  
VG166_BPPZABacillus phage PZA (Bacteriophage PZA)
VG166_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG166_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP16.7

Select_all Deselect_all  
VG167_BPPZABacillus phage PZA (Bacteriophage PZA)
VG167_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG167_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 1ZAE  2BNK  2C5R 

Early protein GP16.8

Select_all Deselect_all  
VG168_BPPZABacillus phage PZA (Bacteriophage PZA)
VG168_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG168_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP16.9

Select_all Deselect_all  
VG169_BPPZABacillus phage PZA (Bacteriophage PZA)
VG169_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG169_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP17

Select_all Deselect_all  
VG17_BPB03Bacillus phage B103 (Bacteriophage B103)
VG17_BPPZABacillus phage PZA (Bacteriophage PZA)
VG17_BPPH5Bacillus phage phi15 (Bacteriophage phi-15)
VG17_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP1A


VG1A_BPPZABacillus phage PZA (Bacteriophage PZA)

Early protein GP1B


VG1B_BPPZABacillus phage PZA (Bacteriophage PZA)

Early protein GP1C


VG1C_BPPZABacillus phage PZA (Bacteriophage PZA)

Late genes activator (Early protein GP4)

Select_all Deselect_all  
VG4_BPB03Bacillus phage B103 (Bacteriophage B103)
VG4_BPNFBacillus phage Nf (Bacteriophage Nf)

Late genes activator (Early protein GP4) (GPF)

VG4_BPPZABacillus phage PZA (Bacteriophage PZA)
VG4_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 2FIO  2FIP 

Early protein GP5B

Select_all Deselect_all  
VG5B_BPPZABacillus phage PZA (Bacteriophage PZA)
VG5B_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Early protein GP6

Select_all Deselect_all  
VG6_BPB03Bacillus phage B103 (Bacteriophage B103)
VG6_BPPZABacillus phage PZA (Bacteriophage PZA)
VG6_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

Head morphogenesis protein (Late protein GP7)

Select_all Deselect_all  
VG7_BPB03Bacillus phage B103 (Bacteriophage B103)
VG7_BPPZABacillus phage PZA (Bacteriophage PZA)
VG7_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 1NO4  1NOH  3MTU  3OA7 

Head fiber protein (Late protein GP8.5)

Select_all Deselect_all  
VG85_BPB03Bacillus phage B103 (Bacteriophage B103)
VG85_BPNFBacillus phage Nf (Bacteriophage Nf)
VG85_BPPZABacillus phage PZA (Bacteriophage PZA)
VG85_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)

pdb 3QC7 

Tail protein (Late protein GP9)

Select_all Deselect_all  
VG9_BPB03Bacillus phage B103 (Bacteriophage B103)
VG9_BPPZABacillus phage PZA (Bacteriophage PZA)
VG9_BPPH2Bacillus phage phi29 (Bacteriophage phi-29)
Swiss Institute of Bioinformatics > ExPASy ( Resources | Disclaimer | Links ) > ViralZone ( Contact us )