Inhibition of host MAVS by virus (kw:KW-1097)

The MAVS protein is required for innate immune defense against viruses. It acts downstream of RIG-I and MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to induction of antiviral cytokines. Alternatively, MAVS can cause apoptosis independent of its function in initiating interferon production. MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane.

RIGI RIGI TRIM25 MAVS STING TRADD TRADD TRAF3 TRAF6 TRAF2 FADD RIP1 TBK1 IKKe IRF3 IRF3 IRF7 IRF7 IKb IKb DDX3 IKKgamma IKKalpha IKKbeta NFKB NFKB NFKB

Some viruses selectively inhibit MAVS function. For example, Hepatitis C virus encodes a specific serine protease NS3/4A which cleaves the MAVS transmembrane domain, removes it from the mitochondria thereby preventing interferon production. In a similar way, Hepatitis A encodes for the ABC protein, which localizes to the mitochondria and inhibits MAVS signaling via proteolytic cleavage.

Matching UniProtKB/Swiss-Prot entries

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209 entries grouped by strain

2 entries

Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain

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NCAP_BRSVA Nucleoprotein (Protein N) (Nucleocapsid protein)
NS1_BRSVA Non-structural protein 1 (Non-structural protein 1C)

2 entries

Human respiratory syncytial virus B (strain B1) reference strain

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NCAP_HRSVB Nucleoprotein (Protein N) (Nucleocapsid protein)
NS1_HRSVB Non-structural protein 1 (Non-structural protein 1C)

2 entries

Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain

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PB2_I34A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I34A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) reference strain

PB2_I33A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Andes orthohantavirus (ANDV) (Andes virus) reference strain

GP_ANDV Envelopment polyprotein (Glycoprotein precursor) (M polyprotein) [Cleaved into: Glycoprotein N (Gn) ...

1 entry

Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1) reference strain

POLG_DEN1W Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM ...

1 entry

Hantaan virus (strain 76-118) (Korean hemorrhagic fever virus) reference strain

GP_HANTV Envelopment polyprotein (Glycoprotein precursor) (M polyprotein) [Cleaved into: Glycoprotein N (Gn) ...

1 entry

Hepatitis C virus genotype 1a (isolate H77) (HCV) reference strain

POLG_HCV77 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Human hepatitis A virus genotype IB (isolate HM175) (HHAV) (Human hepatitis A virus (isolate Human/Australia/HM175/1976)) reference strain

POLG_HAVHM Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human metapneumovirus (strain CAN97-83) (HMPV) reference strain

M22_HMPVC Protein M2-2

1 entry

Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) reference strain

PB1F2_I56A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Duck/England/1/1956 H11N6) reference strain

PB1F2_I56A2 Protein PB1-F2

1 entry

Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd) reference strain

PB1F2_I96A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/USSR/90/1977 H1N1) reference strain

PB2_I77AB Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Poliovirus type 1 (strain Mahoney) reference strain

POLG_POL1M Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Seneca Valley virus (isolate -/United States/SSV-001/2002) (SVV) reference strain

POLG_SVV1 Genome polyprotein [Cleaved into: Leader protein; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 ...

1 entry

Severe acute respiratory syndrome coronavirus (SARS-CoV) reference strain

ORF9B_SARS ORF9b protein (Accessory protein 9b) (ORF-9b) (Protein 9b)

1 entry

Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) reference strain

ORF9B_SARS2 ORF9b protein (ORF9b) (Accessory protein 9b) (ORF-9b) (Protein 9b)

1 entry

Sin Nombre orthohantavirus (SNV) (Sin Nombre virus) reference strain

GP_SINV Envelopment polyprotein (M polyprotein) [Cleaved into: Glycoprotein N (Gn) (Glycoprotein G1); ...

1 entry

Tula orthohantavirus (TULV) (Tula virus) reference strain

GP_TULV Envelopment polyprotein (Glycoprotein precursor) (M polyprotein) [Cleaved into: Glycoprotein N (Gn) ...

1 entry

Uukuniemi virus (strain S23) (UUKV) reference strain

NSS_UUKS Non-structural protein NS-S (NSs)

2 entries

Human respiratory syncytial virus

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NCAP_HRSV Nucleoprotein (Protein N) (Nucleocapsid protein)
NS1_HRSV Non-structural protein 1 (Non-structural protein 1C)

2 entries

Human respiratory syncytial virus A (strain A2)

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NCAP_HRSVA Nucleoprotein (Protein N) (Nucleocapsid protein)
NS1_HRSVA Non-structural protein 1 (NS1) (Non-structural protein 1C)

2 entries

Human respiratory syncytial virus B (strain 18537)

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NCAP_HRSV1 Nucleoprotein (Protein N) (Nucleocapsid protein)
NS1_HRSV1 Non-structural protein 1 (Non-structural protein 1C)

2 entries

Influenza A virus (strain A/Ann Arbor/6/1960 H2N2)

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PB2_I60A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I60A0 Protein PB1-F2

2 entries

Influenza A virus (strain A/Beijing/39/1975 H3N2)

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PB2_I75A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I75A0 Protein PB1-F2

2 entries

Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))

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PB1F2_I18A0 Protein PB1-F2
PB2_I18A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Duck/Germany/1949 H10N7)

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PB2_I49A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I49A1 Protein PB1-F2

2 entries

Influenza A virus (strain A/Henry/1936 H1N1)

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PB1F2_I36A0 Protein PB1-F2
PB2_I36A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Hickox/1940 H1N1)

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PB2_I40A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I40A0 Protein PB1-F2

2 entries

Influenza A virus (strain A/Hong Kong/1/1968 H3N2)

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PB2_I68A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I68A4 Protein PB1-F2

2 entries

Influenza A virus (strain A/Hong Kong/5/1983 H3N2)

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PB2_I83A8 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I83A8 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/1/1971 H3N2)

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PB2_I71A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I71A1 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/101/1972 H3N2)

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PB2_I72A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I72A4 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/102/1972 H3N2)

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PB2_I72A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I72A3 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/110/1976 H3N2)

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PB2_I76A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I76A6 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/18/1978 H3N2)

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PB2_I78A8 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I78A8 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/2/1978 H3N2)

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PB2_I78A7 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I78A7 Protein PB1-F2

2 entries

Influenza A virus (strain A/Memphis/4/1980 H3N2)

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PB2_I80A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I80A4 Protein PB1-F2

2 entries

Influenza A virus (strain A/Port Chalmers/1/1973 H3N2)

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PB2_I73A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I73A5 Protein PB1-F2

2 entries

Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)

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PB1F2_I06A0 Protein PB1-F2
PB2_I06A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/Swine/Colorado/1/1977 H3N2)

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PB2_I77A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I77A4 Protein PB1-F2

2 entries

Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)

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PB1F2_I45A0 Protein PB1-F2
PB2_I45A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Iowa/1943 H1N1)

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PB1F2_I43A0 Protein PB1-F2
PB2_I43A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

2 entries

Influenza A virus (strain A/USA:Phila/1935 H1N1)

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PB1F2_I35A3 Protein PB1-F2
PB2_I35A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))

PB1F2_I33A0 Protein PB1-F2

1 entry

Black Creek Canal orthohantavirus (BCCV) (Black Creek Canal virus)

GP_BCCV Envelopment polyprotein (Glycoprotein precursor) (M polyprotein) [Cleaved into: Glycoprotein N (Gn) ...

1 entry

Bovine respiratory syncytial virus (strain 391-2) (BRS)

NCAP_BRSV3 Nucleoprotein (Protein N) (Nucleocapsid protein)

1 entry

Bovine respiratory syncytial virus (strain Rb94) (BRS)

NCAP_BRSVR Nucleoprotein (Protein N) (Nucleocapsid protein)

1 entry

Coxsackievirus B3 (strain Nancy)

POLG_CXB3N Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B3 (strain Woodruff)

POLG_CXB3W Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Dengue virus type 1 (strain Brazil/97-11/1997) (DENV-1)

POLG_DEN1B Genome polyprotein [Cleaved into: Protein C (Core protein); Protein prM; Peptide pr; Small envelope ...

1 entry

Dengue virus type 1 (strain Singapore/S275/1990) (DENV-1)

POLG_DEN1S Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (isolate Thailand/0168/1979) (DENV-2)

POLG_DEN28 Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain 16681-PDK53) (DENV-2)

POLG_DEN27 Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain Jamaica/1409/1983) (DENV-2)

POLG_DEN2J Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain Peru/IQT2913/1996) (DENV-2)

POLG_DEN2Q Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain Puerto Rico/PR159-S1/1969) (DENV-2)

POLG_DEN2P Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain Thailand/16681/1984) (DENV-2)

POLG_DEN26 Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 2 (strain Thailand/NGS-C/1944) (DENV-2)

POLG_DEN2N Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 3 (strain China/80-2/1980) (DENV-3)

POLG_DEN3C Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 3 (strain Martinique/1243/1999) (DENV-3)

POLG_DEN3M Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 3 (strain Philippines/H87/1956) (DENV-3)

POLG_DEN3P Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 3 (strain Singapore/8120/1995) (DENV-3)

POLG_DEN3I Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 3 (strain Sri Lanka/1266/2000) (DENV-3)

POLG_DEN3S Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 4 (strain Dominica/814669/1981) (DENV-4)

POLG_DEN4D Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 4 (strain Philippines/H241/1956) (DENV-4)

POLG_DEN4P Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 4 (strain Singapore/8976/1995) (DENV-4)

POLG_DEN4S Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 4 (strain Thailand/0348/1991) (DENV-4)

POLG_DEN4T Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dengue virus type 4 (strain Thailand/0476/1997) (DENV-4)

POLG_DEN4H Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

1 entry

Dobrava-Belgrade orthohantavirus (DOBV) (Dobrava virus)

GP_DOBV Envelopment polyprotein (Glycoprotein precursor) (M polyprotein) [Cleaved into: Glycoprotein N (Gn) ...

1 entry

Hepatitis C virus genotype 1a (isolate 1) (HCV)

POLG_HCV1 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate BK) (HCV)

POLG_HCVBK Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate Con1) (HCV)

POLG_HCVCO Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate HC-J1) (HCV)

POLG_HCVJ1 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate HC-JT) (HCV)

POLG_HCVJT Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate HCR6) (HCV)

POLG_HCVR6 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate Japanese) (HCV)

POLG_HCVJA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)

POLG_HCVTW Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1b (strain HC-J4) (HCV)

POLG_HCVJ4 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1c (isolate HC-G9) (HCV)

POLG_HCVH9 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 1c (isolate India) (HCV)

POLG_HCVIN Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2a (isolate HC-J6) (HCV)

POLG_HCVJ6 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2a (isolate JFH-1) (HCV)

POLG_HCVJF Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2b (isolate HC-J8) (HCV)

POLG_HCVJ8 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2b (isolate JPUT971017) (HCV)

POLG_HCVJP Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2c (isolate BEBE1) (HCV)

POLG_HCVBB Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 2k (isolate VAT96) (HCV)

POLG_HCVVA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3a (isolate NZL1) (HCV)

POLG_HCVNZ Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3a (isolate k3a) (HCV)

POLG_HCVK3 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3b (isolate Tr-Kj) (HCV)

POLG_HCVTR Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 3k (isolate JK049) (HCV)

POLG_HCVJK Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 4a (isolate ED43) (HCV)

POLG_HCVED Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 5a (isolate EUH1480) (HCV)

POLG_HCVEV Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 5a (isolate SA13) (HCV)

POLG_HCVSA Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6a (isolate 6a33) (HCV)

POLG_HCV6A Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6a (isolate EUHK2) (HCV)

POLG_HCVEU Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6b (isolate Th580) (HCV)

POLG_HCVT5 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6d (isolate VN235) (HCV)

POLG_HCVVN Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6g (isolate JK046) (HCV)

POLG_HCVJL Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6h (isolate VN004) (HCV)

POLG_HCVVP Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis C virus genotype 6k (isolate VN405) (HCV)

POLG_HCVVO Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1 entry

Hepatitis GB virus B (GBV-B) (GB virus B)

POLG_GBVB Genome polyprotein [Cleaved into: Core protein; Envelope glycoprotein E1; Envelope glycoprotein E2 ...

1 entry

Human enterovirus 71 (EV71) (EV-71)

POLG_HE71 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus 71 (strain 7423/MS/87) (EV71) (EV-71)

POLG_HE71M Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus 71 (strain USA/BrCr/1970) (EV71) (EV-71)

POLG_HE71B Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IA (isolate GBM) (HHAV) (Human hepatitis A virus (isolate Human/Germany/GBM/1976))

POLG_HAVGB Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IA (isolate H2) (HHAV) (Human hepatitis A virus (isolate Human/China/H2/1982))

POLG_HAVH2 Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IA (isolate LA) (HHAV) (Human hepatitis A virus (isolate Human/Northern California/LA/1974))

POLG_HAVLA Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IB (isolate MBB) (HHAV) (Human hepatitis A virus (isolate Human/Northern Africa/MBB/1978))

POLG_HAVMB Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IIA (isolate CF-53) (HHAV) (Human hepatitis A virus (isolate Human/France/CF-53/1979))

POLG_HAVCF Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IIB (isolate SLF88) (HHAV) (Human hepatitis A virus (isolate Human/Sierra Leone/SLF88/1988))

POLG_HAV88 Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IIIA (isolate NOR-21) (HHAV) (Human hepatitis A virus (isolate Human/Norway/NOR-21/1998))

POLG_HAVNO Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human hepatitis A virus genotype IIIB (isolate HAJ85-1) (HHAV) (Human hepatitis A virus (isolate Human/Japan/HAJ85-1/1985))

POLG_HAVJ8 Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human respiratory syncytial virus A (strain S-2) (HRSV-S2)

NS1_HRSS2 Non-structural protein 1 (NS1) (Non-structural protein 1C)

1 entry

Influenza A virus (strain A/Brazil/11/1978 H1N1)

PB2_I77AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/31.2/2002 H5N1 genotype X1)

PB1F2_I02A2 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/37.4/2002 H5N1 genotype X2)

PB1F2_I02A3 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/715.5/2001 H5N1 genotype E)

PB1F2_I01A3 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/96.1/2002 H5N1 genotype Y)

PB1F2_I02A5 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/FY150/2001 H5N1 genotype D)

PB1F2_I01A2 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)

PB1F2_I02A6 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Hong Kong/YU562/2001 H5N1 genotype B)

PB1F2_I01A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Pennsylvania/1/1983 H5N2)

PB1F2_I83A5 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Pennsylvania/1370/1983 H5N2)

PB1F2_I83A6 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Scotland/1959 H5N1)

PB1F2_I59A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Shantou/4231/2003 H5N1 genotype V)

PB1F2_I03A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7)

PB1F2_I85A3 Protein PB1-F2

1 entry

Influenza A virus (strain A/Chile/1/1983 H1N1)

PB2_I83A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

PB2_I96A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Duck/Hokkaido/8/1980 H3N8)

PB1F2_I80A6 Protein PB1-F2

1 entry

Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C)

PB1F2_I00A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/England/878/1969 H3N2)

PB2_I69A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)

PB2_I47A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Goose/Guangxi/345/2005 H5N1 genotype G)

PB1F2_I05A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Grey teal/Australia/2/1979 H4N4)

PB1F2_I79A7 Protein PB1-F2

1 entry

Influenza A virus (strain A/Guinea fowl/Hong Kong/38/2002 H5N1 genotype X0)

PB1F2_I02A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Gull/Maryland/704/1977 H13N6)

PB1F2_I77AF Protein PB1-F2

1 entry

Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)

PB1F2_I97A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/Hong Kong/212/2003 H5N1 genotype Z+)

PB1F2_I03A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/India/6263/1980 H1N1)

PB2_I80AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Japan/305/1957 H2N2)

PB2_I57A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Kiev/59/1979 H1N1)

PB2_I79A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Kitakyushu/159/1993 H3N2)

PB2_I93A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Korea/426/1968 H2N2)

PB2_I68A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Leningrad/134/17/1957 H2N2)

PB2_I57A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Leningrad/134/1957 H2N2)

PB2_I57A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Leningrad/134/47/1957 H2N2)

PB2_I57A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)

PB2_I54A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Memphis/8/1988 H3N2)

PB2_I88A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)

PB2_I00A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60)) (Influenza A virus (strain A/NT/60/1968 H3N2))

PB2_I68A6 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Qu/7/1970 H3N2)

PB2_I70A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7)

PB1F2_I80A2 Protein PB1-F2

1 entry

Influenza A virus (strain A/Silky Chicken/Hong Kong/SF189/2001 H5N1 genotype A)

PB1F2_I01A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/Silky Chicken/Hong Kong/YU100/2002 H5N1 genotype X3)

PB1F2_I02A4 Protein PB1-F2

1 entry

Influenza A virus (strain A/Singapore/1/1957 H2N2)

PB2_I57A5 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)

PB2_I30A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)

PB2_I77AC Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)

PB2_I61A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)

PB2_I67A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Teal/China/2978.1/2002 H5N1 genotype W)

PB1F2_I02A7 Protein PB1-F2

1 entry

Influenza A virus (strain A/Tokyo/3/1967 H2N2)

PB2_I67A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)

PB1F2_I83A4 Protein PB1-F2

1 entry

Influenza A virus (strain A/Turkey/Minnesota/501/1978 H6N8)

PB1F2_I78AC Protein PB1-F2

1 entry

Influenza A virus (strain A/Turkey/Minnesota/833/1980 H4N2)

PB1F2_I80A8 Protein PB1-F2

1 entry

Influenza A virus (strain A/Turkey/Ontario/6118/1968 H8N4)

PB1F2_I68A3 Protein PB1-F2

1 entry

Influenza A virus (strain A/Turkey/Ontario/7732/1966 H5N9)

PB1F2_I66A0 Protein PB1-F2

1 entry

Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2)

PB1F2_I66A1 Protein PB1-F2

1 entry

Influenza A virus (strain A/USA:Albany/12/1951 H1N1)

PB2_I51A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)

PB2_I96A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)

PB2_I07A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Udorn/307/1972 H3N2)

PB2_I72A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/Victoria/3/1975 H3N2)

PB2_I75A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Influenza A virus (strain A/X-31 H3N2)

PB2_I000X Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

1 entry

Ovine respiratory syncytial virus (strain WSU 83-1578) (ORSV)

NS1_ORSVW Non-structural protein 1 (Non-structural protein 1C)

1 entry

Poliovirus type 1 (strain Sabin)

POLG_POL1S Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 2 (strain Lansing)

POLG_POL2L Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 2 (strain W-2)

POLG_POL2W Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 3 (strain 23127)

POLG_POL32 Genome polyprotein [Cleaved into: P3; Protein 3AB; P1; Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Poliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)

POLG_POL3L Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Simian hepatitis A virus genotype V (isolate AGM-27) (SHAV) (Simian hepatitis A virus (isolate Cercopithecus/Kenya/AGM-27/1985))

POLG_HAVS2 Genome polyprotein [Cleaved into: Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...