Herelleviridae (taxid:2560065)

VIRION

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Non-enveloped, head-tail structure with Myo-type morphology. Heads are about 84-94 nm in diameter and and tails 140-219 in length. The tail is contractile with globular structures at its tip, has 6 long terminal fibers, 6 short spikes and a double base plate. The capsid has a T=16 symmetry (SPO1-like viruses).

GENOME

Linear, dsDNA genome of 130-140 kb, encoding for about 190-215 proteins.

GENE EXPRESSION

Genes are transcribed by operons. Some Twortvirus might have circularly permuted genomes.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm by contraction of the tail sheath.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA. Transcription and translation of late genes.
  5. Assembly of an empty procapsid and packaging of the genome.
  6. Viral tail fibers assembly and viral tail assembly.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

63 entries grouped by protein

3 entries

Anti-Pycsar protein Apyc1 (Apyc1)

Select_allDeselect_all
ACPY1_BP010
Bacillus phage 010DV004 reference strain
ACPY1_BPGO3
Bacillus phage vB_BsuM-Goe3 reference strain
ACPY1_BPGO7
Bacillus phage vB_BveM-Goe7

2 entries

Anti-Pycsar protein Apyc1 (Apyc1)

Select_allDeselect_all
APYC1_BPBSP
Bacillus phage BSP38 reference strain
APYC1_BPSBS
Bacillus phage SBSphiJ

1 entry

Virion protein 3 (Gene product 40) (gp40)

BP40_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

3 entries

Major capsid protein (Major head protein)

Select_allDeselect_all
CAPSD_BPPGK
Staphylococcus phage K
CAPSD_BPS24
Staphylococcus phage S25-4
CAPSD_BPS25
Staphylococcus phage S25-3

1 entry

DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

DPOL_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Deoxyuridylate hydroxymethyltransferase (Deoxyuridylate hydroxymethylase) (EC 2.1.2.-) (Gp29) (dUMP hydroxymethylase) (dUMP-HMase)

DUHM_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain

4 entries

Endolysin (EC 3.5.1.28) (Probable N-acetylmuramoyl-L-alanine amidase)

Select_allDeselect_all
ENLYS_BPA51
Listeria phage A511 (Bacteriophage A511)
ENLYS_BPG15
Staphylococcus phage G15

Endolysin LysGH15 (D-alanyl-glycyl endopeptidase) (EC 3.4.22.-) (N-acetylmuramoyl-L-alanine amidase) (EC 3.5.1.28)

ENLYS_BPPGK
Staphylococcus phage K

Endolysin LysK (D-alanyl-glycyl endopeptidase) (EC 3.4.22.-) (N-acetylmuramoyl-L-alanine amidase) (EC 3.5.1.28)

ENLYS_BPTWO
Staphylococcus phage Twort (strain DSM 17442 / HER 48) (Bacteriophage Twort)

Endolysin PlyTW (D-alanyl-glycyl endopeptidase) (EC 3.4.22.-) (N-acetylmuramoyl-L-alanine amidase) (EC 3.5.1.28)

1 entry

Gene product 168 (gp168)

GP168_BPTWO
Staphylococcus phage Twort (strain DSM 17442 / HER 48) (Bacteriophage Twort) reference strain

1 entry

Gene 27 protein

GP27_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Gene 30 protein (GP30)

GP30_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Gene 33 protein

GP33_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 37 protein

GP37_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 38 protein

GP38_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 39 protein

GP39_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Gene 40 protein

GP40_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 41 protein

GP41_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 42 protein

GP42_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

E22 protein (Gene 43 protein)

GP43_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

E3 protein (Gene 44 protein)

GP44_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 45 protein

GP45_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Inhibitor of histone-like protein HU (Gene 46 protein) (Gp46) (Gene product 46)

GP46_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain

1 entry

Putative gene 47 protein

GP47_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 48 protein

GP48_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 49 protein

GP49_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 50 protein

GP50_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 51 protein

GP51_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 52 protein

GP52_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 53 protein

GP53_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 54 protein

GP54_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 55 protein

GP55_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Inhibitor of host cell division protein (Gene 56 protein) (Gp56)

GP56_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain

1 entry

Putative gene 57 protein

GP57_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 58 protein

GP58_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 59 protein

GP59_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Putative gene 60 protein

GP60_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Hachiman anti-defense 1 (Had1)

HAD1_BPPS7
Bacillus phage SBSphiJ4

1 entry

5-hmdU DNA kinase (5-hydroxymethyluracil DNA kinase) (P-loop kinase) (gp186)

HMUDK_BPS10
Bacillus phage SP10 (Bacillus phage SP-10) reference strain

1 entry

DNA endonuclease I-HmuI (EC 3.1.-.-) (HNH homing endonuclease I-HmuI)

HMUI_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

3 entries

Probable portal protein

Select_allDeselect_all
PORTL_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain
PORTL_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain
PORTL_BPTWO
Staphylococcus phage Twort (strain DSM 17442 / HER 48) (Bacteriophage Twort) reference strain

1 entry

RNA polymerase sigma GP28 factor

RP28_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

RNA polymerase sigma GP34 factor

RP34_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

1 entry

Thoeris anti-defense 1 (Tad1)

TAD1_BPPSB
Bacillus phage SBSphiJ7

1 entry

Thoeris anti-defense 2 (Tad2)

TAD2_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain

1 entry

Transcription factor 1

TF1_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)

2 entries

Tail sheath protein (TSP)

Select_allDeselect_all
TSP_BPSP1
Bacillus phage SP01 (Bacteriophage SP01) reference strain
TSP_BPTWO
Staphylococcus phage Twort (strain DSM 17442 / HER 48) (Bacteriophage Twort) reference strain

1 entry

Putative tail sheath protein

VPN1_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Putative major capsid protein

VPN2_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Virion protein 4

VPN4_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Virion protein 5

VPN5_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Virion protein 6

VPN6_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Tail fiber protein

VPN7_BPPHE
Enterococcus phage phiEF24C (Enterococcus bacteriophage phi-EF24C) reference strain

1 entry

Uncharacterized 16.2 kDa protein in gene 29 5'region

YG29_BPSP1
Bacillus phage SP01 (Bacteriophage SP01)