Alphaherpesvirinae

VIRION

image

Enveloped, spherical to pleomorphic, 150-200 nm in diameter, T=16 icosahedral symmetry. The capsid consists of 162 capsomers and is surrounded by an amorphous tegument. Glycoproteins complexes are embedded in the lipid envelope.

GENOME

Monopartite, linear, dsDNA genome of 120-180 kb. The genome contains terminal and internal reiterated sequences.

GENE EXPRESSION

Each viral transcript usually encodes a single protein and has a promoter/regulatory sequence, a TATA box, a transcription initiation site, a 5' leader sequence of 30-300 bp (not translated), a 3' nontranslated sequence of 10-30 bp, and a poly A signal. There are many gene overlaps. There are only few spliced genes. Some of the expressed ORFs are antisense to each other. Some ORFs can be accessed from more than one promoter. There are some non-coding genes.

There are three types of genes: immediate-early (?), early(?) and late (?). The ? genes are transcribed immediately after infection and ensure the transcription of ? genes, which encode the proteins necessary for the viral replication. The ? genes mostly encode structural proteins. Standing apart are genes expressed during latency.

The viral proteins VHS and ICP27 are involved in shut-off of host protein translation in order to ensure the selective expression of viral proteins versus cellular proteins.

REPLICATION

NUCLEAR

Lytic replication:

  1. Attachment of the viral gB, gC, gD and gH proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the core and the tegument proteins into the host cytoplasm.
  3. The capsid is transported to the nuclear pore where viral DNA is released into the nucleus.
  4. Transcription of immediate early genes which promote transcription of early genes and protect the virus against innate host immunity.
  5. Transcription of early viral mRNA by host polymerase II, encoding proteins involved in replication of the viral DNA.
  6. A first round of circular genome amplification occurs by bidirectional replication
  7. Synthesis of linear concatemer copies of viral DNA by rolling circle.
  8. Transcription of late mRNAs by host polymerase II, encoding structural proteins.
  9. Assembly of the virus in nuclear viral factories and budding through the inner lamella of the nuclear membrane which has been modified by the insertion of herpes glycoproteins, throughout the Golgi and final release at the plasma membrane.

Latent replication : replication of circular viral episome in tandem with the host cell DNA using the host cell replication machinery.

Host-virus interaction

Adaptive immune response inhibition

Alpha-herpesviruses have evolved different strategies to inhibit the host adaptive immune response. For example, Herpes simplex protein US12 binds specifically to transporters associated with antigen processing (TAP), blocking peptide-binding to TAP and subsequent loading of peptides onto MHC class I molecules . VZV ORF66 downregulates MHC I expression by impairing the transport of MHC I molecules from the Golgi compartment to the cell surface

Apoptosis modulation

Apoptosis is very often modulated (and usually inhibited) by alpha-herpesviruses. Herpes virus simplex protein US3 activates host protein kinase A/PKA to block apoptosis. Additionally, it also interacts with programmed cell death protein 4 (PDCD4) and retains it in the nucleus thereby inhibiting host apoptosis .

Autophagy modulation

Several alpha-herpesviruses are able to inhibit host cell autophagy process, such as HHV-1 ICP34.5 that interacts with Beclin-1 and stop autophagosomes development .

Cell-cycle modulation

The UL24 protein that is present in all herpesvirus subfamilies (alpha, beta and gamma-herpesviruses) induces a cell cycle arrest at G2/M transition through inactivation of the host cyclinB/cdc2 complex .

Innate immune response inhibition

Herpes viruses inhibit the cascade leading to production of interferon-beta by mainly targeting the host IRF3 protein. Thus, herpes simplex virus or varicella virus possess proteins to prevent IRF3 activation.

Host splicing inhibition

HSV-1 ICP27 is an alternative splicing regulator of host mRNA. This protein is conserved in several herpesviridae genera. It has been shown to act as a splicing silencer at the 3' splice site of the PML intron 7a .

Matching UniProtKB/Swiss-Prot entries

788 entries grouped by strain (browse by keywords)

90 entries

Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

Select_allDeselect_all
VG11_GAHVM Uncharacterized gene 11 protein
VG02_GAHVM Uncharacterized gene 2 protein
VG12_GAHVM Uncharacterized gene 12 protein
VG97_GAHVM Uncharacterized gene 97 protein
US02_GAHVM Protein US2 homolog
UL24_GAHVM Protein UL24 homolog
UL13_GAHVM Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
US03_GAHVM Protein kinase US3 homolog (EC 2.7.11.1)
CEP2_GAHVM Cytoplasmic envelopment protein 2
GK_GAHVM Envelope glycoprotein K
ICP22_GAHVM Transcriptional regulator ICP22 homolog (Immediate early ICP22-like protein)
ICP27_GAHVM mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
ICP4_GAHVM Major viral transcription factor ICP4 homolog (Immediate-early protein IE175)
TG21_GAHVM Tegument protein UL21 homolog
TRX2_GAHVM Triplex capsid protein 2
VG04_GAHVM Uncharacterized gene 4 protein
TRM1_GAHVM Tripartite terminase subunit 1
VG06A_GAHVM Uncharacterized gene 6a protein
TEG6_GAHVM Tegument protein UL55 homolog
NEC2_GAHVM Nuclear egress protein 2
PRIM_GAHVM DNA primase (EC 2.7.7.-)
RIR1_GAHVM Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TEG5_GAHVM Tegument protein UL47 homolog
TEG3_GAHVM Tegument protein UL14 homolog
VG87_GAHVM Uncharacterized gene 87 protein
MEQ_GAHVM Oncoprotein MEQ (MEQ)
PP38_GAHVM Phosphoprotein pp38
TRM3_GAHVM Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
VG83_GAHVM Uncharacterized gene 83 protein
VG90_GAHVM Uncharacterized gene 90 protein
SHUT_GAHVM Virion host shutoff protein (Vhs) (EC 3.1.27.-)
SCP_GAHVM Small capsomere-interacting protein
UL4_GAHVM Nuclear protein UL4 homolog
ITP_GAHVM Inner tegument protein
PP24_GAHVM Phosphoprotein pp24
IL8H_GAHVM Viral interleukin-8 homolog (vIL8)
NP03_GAHVM Nuclear phosphoprotein UL3 homolog
PORTL_GAHVM Portal protein
NEC1_GAHVM Nuclear egress protein 1
VG69_GAHVM Uncharacterized gene 69 protein
VG82_GAHVM Uncharacterized gene 82 protein
VG93_GAHVM Uncharacterized gene 93 protein
VG06B_GAHVM Uncharacterized gene 6b protein
VP16_GAHVM Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
VG71_GAHVM Uncharacterized gene 71 protein
UL20_GAHVM Protein UL20 homolog
VG81_GAHVM Uncharacterized gene 81 protein
VG85_GAHVM Uncharacterized gene 85 protein
VLIP_GAHVM Virulence factor MDV010 (Viral lipase homolog) (vLIP)
US10_GAHVM Virion protein US10 homolog
VG09_GAHVM Uncharacterized gene 9 protein
UL32_GAHVM Packaging protein UL32 homolog
TRM2_GAHVM Tripartite terminase subunit 2
TEG7_GAHVM Tegument protein UL51 homolog
SCAF_GAHVM Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
TEG1_GAHVM Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
VG01_GAHVM Uncharacterized gene 1 protein
RIR2_GAHVM Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
PAP_GAHVM DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
VG86_GAHVM Uncharacterized gene 86 protein
UNG_GAHVM Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TRX1_GAHVM Triplex capsid protein 1
VG72_GAHVM Uncharacterized gene 72 protein
VP22_GAHVM Tegument protein VP22
VG07_GAHVM Uncharacterized gene 7 protein
AN_GAHVM Alkaline nuclease (EC 3.1.-.-)
GC_GAHVM Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)
GH_GAHVM Envelope glycoprotein H (gH)
DUT_GAHVM Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
HEPA_GAHVM DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
CEP3_GAHVM Cytoplasmic envelopment protein 3
CVC1_GAHVM Capsid vertex component 1
DNBI_GAHVM Major DNA-binding protein
GI_GAHVM Envelope glycoprotein I
EV45_GAHVM Envelope protein UL45 homolog
GN_GAHVM Envelope glycoprotein N
DPOL_GAHVM DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
HELI_GAHVM DNA replication helicase (EC 3.6.4.-)
CEP1_GAHVM Cytoplasmic envelopment protein 1
GB_GAHVM Envelope glycoprotein B (gB)
LTP_GAHVM Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
GE_GAHVM Envelope glycoprotein E (gE)
CVC2_GAHVM Capsid vertex component 2
GM_GAHVM Envelope glycoprotein M (gM)
GL_GAHVM Envelope glycoprotein L (gL)
KITH_GAHVM Thymidine kinase (EC 2.7.1.21)
MB43_GAHVM Membrane protein UL43 homolog
OBP_GAHVM Replication origin-binding protein (OBP) (OriBP)
MCP_GAHVM Major capsid protein (MCP)
GD_GAHVM Envelope glycoprotein D (gD)

75 entries

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

Select_allDeselect_all
TEG1_EHV1B Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
US02_EHV1B Gene 68 protein
VG34_EHV1B Gene 34 protein
TEG7_EHV1B Tegument protein UL51 homolog
UNG_EHV1B Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TRM3_EHV1B Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TRX1_EHV1B Triplex capsid protein 1
VG01_EHV1B Uncharacterized gene 1 protein
UL20_EHV1B Protein UL20 homolog
VG59_EHV1B Uncharacterized gene 59 protein
ICP22_EHV1B Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
ICP27_EHV1B mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
ICP4_EHV1B Major viral transcription factor (155 kDa immediate-early protein)
TEG6_EHV1B Tegument protein UL55 homolog
TEG4_EHV1B Tegument protein UL21 homolog
PRIM_EHV1B DNA primase (EC 2.7.7.-)
TEG3_EHV1B Tegument protein UL14 homolog
NP03_EHV1B Nuclear phosphoprotein UL3 homolog (ORF60 protein)
HEPA_EHV1B DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
TRM1_EHV1B Tripartite terminase subunit 1
UL24_EHV1B Protein UL24 homolog
UL13_EHV1B Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
RIR1_EHV1B Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
SCAF_EHV1B Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural gene ...
GN_EHV1B Envelope glycoprotein N
PAP_EHV1B DNA polymerase processivity factor (DNA-binding gene 18 protein) (Polymerase accessory protein) ...
ITP_EHV1B Inner tegument protein
GI_EHV1B Envelope glycoprotein I
ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ICP0)
PORTL_EHV1B Portal protein
US03_EHV1B Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
VP16_EHV1B Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
TRM2_EHV1B Tripartite terminase subunit 2
UL32_EHV1B Packaging protein UL32 homolog
US9_EHV1B Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
VG75_EHV1B Uncharacterized gene 75 protein
VP22_EHV1B Tegument protein VP22 (Gene 11 protein)
US10_EHV1B Virion protein US10 homolog (Gene 66 protein)
TRX2_EHV1B Triplex capsid protein 2
RIR2_EHV1B Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
GG_EHV1B Envelope glycoprotein G (gG)
SCP_EHV1B Small capsomere-interacting protein
VG02_EHV1B Uncharacterized gene 2 protein
SHUT_EHV1B Virion host shutoff protein (Vhs) (EC 3.1.27.-)
VG03_EHV1B Gene 3 protein
TEG5_EHV1B Tegument protein UL47 homolog (GP10)
VG67_EHV1B Uncharacterized gene 67 protein (IR6 protein)
CEP1_EHV1B Cytoplasmic envelopment protein 1
DPOL_EHV1B DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GB_EHV1B Envelope glycoprotein B (gB)
GM_EHV1B Envelope glycoprotein M (gM)
CVC2_EHV1B Capsid vertex component 2
DUT_EHV1B Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GK_EHV1B Envelope glycoprotein K (Syncytial protein)
GC_EHV1B Envelope glycoprotein C (gC) (Glycoprotein 13)
GH_EHV1B Envelope glycoprotein H (gH)
HELI_EHV1B DNA replication helicase (EC 3.6.4.-)
GE_EHV1B Envelope glycoprotein E (gE)
GL_EHV1B Envelope glycoprotein L (gL)
GP2_EHV1B Glycoprotein gp2 (Glycoprotein X) (GpX)
EV45_EHV1B Envelope protein UL45 homolog
LTP_EHV1B Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
DNBI_EHV1B Major DNA-binding protein
CVC1_EHV1B Capsid vertex component 1
AN_EHV1B Alkaline nuclease (EC 3.1.-.-)
CEP2_EHV1B Cytoplasmic envelopment protein 2
CEP3_EHV1B Cytoplasmic envelopment protein 3
NEC1_EHV1B Nuclear egress protein 1
KITH_EHV1B Thymidine kinase (EC 2.7.1.21)
MB43_EHV1B Membrane protein UL43 homolog (Membrane protein ORF17)
GD_EHV1B Envelope glycoprotein D (gD) (Glycoprotein 17/18)
NEC2_EHV1B Nuclear egress protein 2
NP04_EHV1B Nuclear protein UL4 homolog
MCP_EHV1B Major capsid protein (MCP)
OBP_EHV1B Replication origin-binding protein (OriBP) (OBP)

73 entries

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

Select_allDeselect_all
US02_HHV11 Protein US2
VP16_HHV11 Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
EV45_HHV11 Envelope protein UL45 (18 kDa protein)
ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Alpha-0 protein) (Immediate-early protein IE110) ...
ICP22_HHV11 Transcriptional regulator ICP22 (Immediate-early protein IE68) (Infected cell protein 22) (ICP22)
ICP27_HHV11 mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)
ICP34_HHV11 Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
ICP47_HHV11 ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...
ICP4_HHV11 Major viral transcription factor ICP4 (Alpha-4 protein) (Infected cell protein 4) (Transcriptional ...
TEG1_HHV11 Tegument protein UL46 (Tegument protein VP11/12)
UL13_HHV11 Serine/threonine-protein kinase UL13 (EC 2.7.11.1) (Virion protein VMW57)
UL32_HHV11 Packaging protein UL32
TEG6_HHV11 Tegument protein UL55
RIR1_HHV11 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
RIR2_HHV11 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
RNB_HHV11 Accessory factor US11 (Vmw21)
TRM3_HHV11 Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TEG5_HHV11 Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
TEG7_HHV11 Tegument protein UL51
UNG_HHV11 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
US03_HHV11 Serine/threonine-protein kinase US3 (EC 2.7.11.1)
NP03_HHV11 Nuclear phosphoprotein UL3
SCAF_HHV11 Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
SCP_HHV11 Small capsomere-interacting protein
TEG4_HHV11 Tegument protein UL21
ITP_HHV11 Inner tegument protein (EC 3.5.1.-) (EC 3.5.1.44) (Viral deamidase UL37)
NEC1_HHV11 Nuclear egress protein 1
LTP_HHV11 Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
MB43_HHV11 Membrane protein UL43
GH_HHV11 Envelope glycoprotein H (gH)
PAP_HHV11 DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
SHUT_HHV11 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
US10_HHV11 Virion protein US10
TRX2_HHV11 Triplex capsid protein 2
US9_HHV11 Envelope protein US9 (10 kDa protein)
VP22_HHV11 Tegument protein VP22
US8A_HHV11 Protein US8.5
TRM2_HHV11 Tripartite terminase subunit 2
UL24_HHV11 Protein UL24
UL56_HHV11 Protein UL56
UL20_HHV11 Protein UL20
TEG3_HHV11 Tegument protein UL14
PRIM_HHV11 DNA primase (EC 2.7.7.-)
TRM1_HHV11 Tripartite terminase subunit 1
TRX1_HHV11 Triplex capsid protein 1
CEP3_HHV11 Cytoplasmic envelopment protein 3
GJ_HHV11 Envelope glycoprotein J
GL_HHV11 Envelope glycoprotein L (gL)
GC_HHV11 Envelope glycoprotein C
DUT_HHV11 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
DPOL_HHV11 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GB_HHV11 Envelope glycoprotein B (gB)
GI_HHV11 Envelope glycoprotein I (gI)
GD_HHV11 Envelope glycoprotein D (gD)
GE_HHV11 Envelope glycoprotein E (gE) (gE-1)
MCP_HHV11 Major capsid protein (MCP)
GK_HHV11 Envelope glycoprotein K (Syncytial protein)
CVC2_HHV11 Capsid vertex component 2
AN_HHV11 Alkaline nuclease (EC 3.1.-.-)
CVC1_HHV11 Capsid vertex component 1
CEP1_HHV11 Cytoplasmic envelopment protein 1
CEP2_HHV11 Cytoplasmic envelopment protein 2
DNBI_HHV11 Major DNA-binding protein
KITH_HHV11 Thymidine kinase (EC 2.7.1.21)
HELI_HHV11 DNA replication helicase (EC 3.6.4.-)
NEC2_HHV11 Nuclear egress protein 2
GN_HHV11 Envelope glycoprotein N
GM_HHV11 Envelope glycoprotein M (gM)
HEPA_HHV11 DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
PORTL_HHV11 Portal protein
OBP_HHV11 Replication origin-binding protein (OBP) (OriBP)
NP04_HHV11 Nuclear protein UL4
GG_HHV11 Envelope glycoprotein G (gG) (gG-1)

72 entries

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

Select_allDeselect_all
TEG3_HHV2H Tegument protein UL14
UL20_HHV2H Protein UL20
US02_HHV2H Protein US2
ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferaseICP0) (VMW118 ...
ICP22_HHV2H E3 ubiquitin ligase ICP22 (Immediate-early protein IE68) (Infected cell protein 22) (ICP22)
ICP27_HHV2H mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)
ICP34_HHV2H Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
ICP47_HHV2H ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...
ICP4_HHV2H Major viral transcription factor ICP4 homolog (Alpha-4 protein) (Infected cell protein 4) ...
TEG6_HHV2H Tegument protein UL55
TRM1_HHV2H Tripartite terminase subunit 1
UL24_HHV2H Protein UL24
TRX1_HHV2H Triplex capsid protein 1
VP16_HHV2H Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
GD_HHV2H Envelope glycoprotein D (gD)
TRM3_HHV2H Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
RIR2_HHV2H Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SCP_HHV2H Small capsomere-interacting protein
US9_HHV2H Envelope protein US9 (10 kDa protein)
OBP_HHV2H Replication origin-binding protein (OBP) (OriBP)
PRIM_HHV2H DNA primase (EC 2.7.7.-)
UL13_HHV2H Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
TRX2_HHV2H Triplex capsid protein 2
TEG1_HHV2H Tegument protein UL46 (Tegument protein VP11/12)
TEG4_HHV2H Tegument protein UL21
HEPA_HHV2H DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
PAP_HHV2H DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
NEC2_HHV2H Nuclear egress protein 2
LTP_HHV2H Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
MB43_HHV2H Membrane protein UL43
UL32_HHV2H Packaging protein UL32
US10_HHV2H Virion protein US10
US8A_HHV2H Protein US8.5
VP22_HHV2H Tegument protein VP22
TRM2_HHV2H Tripartite terminase subunit 2
UL56_HHV2H Protein UL56
RNB_HHV2H Probable RNA-binding protein
RIR1_HHV2H Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
SHUT_HHV2H Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG5_HHV2H Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
TEG7_HHV2H Tegument protein UL51
SCAF_HHV2H Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
UNG_HHV2H Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
US03_HHV2H Serine/threonine-protein kinase US3 (EC 2.7.11.1)
EV45_HHV2H Envelope protein UL45 (18 kDa protein)
CVC2_HHV2H Capsid vertex component 2
DPOL_HHV2H DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GM_HHV2H Envelope glycoprotein M (gM)
GI_HHV2H Envelope glycoprotein I (gI)
GK_HHV2H Envelope glycoprotein K (Syncytial protein)
GE_HHV2H Envelope glycoprotein E (gE) (gE-2)
DNBI_HHV2H Major DNA-binding protein
GB_HHV2H Envelope glycoprotein B (gB)
GJ_HHV2H Envelope glycoprotein J
CEP1_HHV2H Cytoplasmic envelopment protein 1
GH_HHV2H Envelope glycoprotein H (gH)
GL_HHV2H Envelope glycoprotein L (gL)
GN_HHV2H Envelope glycoprotein N
GG_HHV2H Envelope glycoprotein G (gG) (gG-2)
DUT_HHV2H Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
CEP2_HHV2H Cytoplasmic envelopment protein 2
CEP3_HHV2H Cytoplasmic envelopment protein 3
NP03_HHV2H Nuclear phosphoprotein UL3
KITH_HHV2H Thymidine kinase (EC 2.7.1.21)
NP04_HHV2H Nuclear protein UL4
GC_HHV2H Envelope glycoprotein C
ITP_HHV2H Inner tegument protein
MCP_HHV2H Major capsid protein (MCP)
PORTL_HHV2H Portal protein
HELI_HHV2H DNA replication helicase (EC 3.6.4.-)
NEC1_HHV2H Nuclear egress protein 1
CVC1_HHV2H Capsid vertex component 1

71 entries

Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain

Select_allDeselect_all
UL43_PSHV1 Membrane protein UL43
UL15B_PSHV1 Large terminase protein homolog UL15b
UL13_PSHV1 Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
TRX1_PSHV1 Triplex capsid protein 1
ICP4_PSHV1 Major viral transcription factor ICP4 homolog
TRX2_PSHV1 Triplex capsid protein 2
US03_PSHV1 Protein kinase US3 homolog (EC 2.7.11.1)
SHUT_PSHV1 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG5_PSHV1 Tegument protein UL47 homolog
TEG7_PSHV1 Tegument protein UL51
ORFD_PSHV1 Uncharacterized protein ORFD
RIR2_PSHV1 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SCP_PSHV1 Small capsomere-interacting protein
RIR1_PSHV1 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TG21_PSHV1 Tegument protein UL21
TRM2_PSHV1 Tripartite terminase subunit 2
NEC1_PSHV1 Nuclear egress protein 1
UL32_PSHV1 Packaging protein UL32
NP04_PSHV1 Nuclear protein UL4
NEC2_PSHV1 Nuclear egress protein 2
PORTL_PSHV1 Portal protein
HEPA_PSHV1 DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
PAP_PSHV1 DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
ORF3_PSHV1 Uncharacterized protein sORF3/4
VP22_PSHV1 Tegument protein VP22
TEG2_PSHV1 Tegument protein UL11
TRM1_PSHV1 Tripartite terminase subunit 1
UL24_PSHV1 Protein UL24
TRM3_PSHV1 Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
UL03_PSHV1 Uncharacterized protein UL3
TEG3_PSHV1 Tegument protein UL14
UNG_PSHV1 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
UL20_PSHV1 Protein UL20
ORF2_PSHV1 Uncharacterized protein sORF2
SCAF_PSHV1 Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
GB_PSHV1 Envelope glycoprotein B (gB)
UL01_PSHV1 Uncharacterized protein UL-1
OBP_PSHV1 Replication origin-binding protein (OBP) (OriBP)
ORFB_PSHV1 Uncharacterized protein ORFB
ORFC_PSHV1 Uncharacterized protein ORFC
PRIM_PSHV1 DNA primase (EC 2.7.7.-)
US10_PSHV1 Virion protein US10 homolog
US02_PSHV1 Uncharacterized protein US2
ITP_PSHV1 Inner tegument protein
GD_PSHV1 Envelope glycoprotein D (gD)
EV45_PSHV1 Envelope protein UL45
KITH_PSHV1 Thymidine kinase (EC 2.7.1.21)
DUT_PSHV1 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GC_PSHV1 Envelope glycoprotein C
DPOL_PSHV1 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GI_PSHV1 Envelope glycoprotein I
GM_PSHV1 Envelope glycoprotein M (gM)
GE_PSHV1 Envelope glycoprotein E (gE)
GK_PSHV1 Envelope glycoprotein K (Syncytial protein)
ICP27_PSHV1 mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27)
GH_PSHV1 Envelope glycoprotein H (gH)
CEP2_PSHV1 Cytoplasmic envelopment protein 2
AN_PSHV1 Alkaline nuclease (EC 3.1.-.-)
CVC1_PSHV1 Capsid vertex component 1
CEP1_PSHV1 Cytoplasmic envelopment protein 1
ATI2_PSHV1 Alpha trans-inducing factor (Tegument protein UL46) (Tegument protein VP11/12)
CVC2_PSHV1 Capsid vertex component 2
DNBI_PSHV1 Major DNA-binding protein
MCP_PSHV1 Major capsid protein (MCP)
GG_PSHV1 Glycoprotein G
GL_PSHV1 Envelope glycoprotein L (gL)
LTP_PSHV1 Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
ORFE_PSHV1 Uncharacterized protein ORFE
GN_PSHV1 Envelope glycoprotein N
HELI_PSHV1 DNA replication helicase (EC 3.6.4.-)
ORFA_PSHV1 Uncharacterized protein ORFA

69 entries

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

Select_allDeselect_all
TEG5_VZVD Tegument protein UL47 homolog
GE_VZVD Envelope glycoprotein E (gE)
ICP22_VZVD Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
ICP27_VZVD mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4) (Transcriptional transactivator ...
ICP4_VZVD Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
TEG6_VZVD Tegument protein UL55 homolog
TRX2_VZVD Triplex capsid protein 2
SCAF_VZVD Capsid scaffolding protein (Protease precursor) (pPR) [Cleaved into: Assemblin (EC 3.4.21.97) ...
RIR1_VZVD Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
SCP_VZVD Small capsomere-interacting protein
ORF57_VZVD Uncharacterized protein 57 (Uncharacterized ORF57 protein)
ORF2_VZVD Membrane protein 2 (Membrane ORF2 protein)
PORTL_VZVD Portal protein
TEG4_VZVD Tegument protein UL21 homolog
TYSY_VZVD Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
US9_VZVD Envelope protein US9 (Envelope protein 65) (ORF65 protein)
OBP_VZVD Replication origin-binding protein (OBP) (OriBP)
NP04_VZVD Nuclear protein UL4 homolog (ORF56 protein)
PAP_VZVD DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
HEPA_VZVD DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
NEC1_VZVD Nuclear egress protein 1
UNG_VZVD Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VP16_VZVD Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
TEG7_VZVD Tegument protein UL51 homolog (ORF7 protein)
TRX1_VZVD Triplex capsid protein 1
TRM1_VZVD Tripartite terminase subunit 1
UL13_VZVD Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
TRM2_VZVD Tripartite terminase subunit 2
TRM3_VZVD Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit) [Cleaved into: Gene 42 ...
UL32_VZVD Packaging protein UL32
UL24_VZVD Protein UL24 homolog
ORF32_VZVD Phosphoprotein 32 (ORF32 Phosphoprotein)
PRIM_VZVD DNA primase (EC 2.7.7.-)
SHUT_VZVD Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG3_VZVD Tegument protein UL14 homolog
TEG1_VZVD Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
US10_VZVD Virion protein US10 homolog (Genes 64/69 protein)
ORF0_VZVD Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)
RIR2_VZVD Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
UL20_VZVD Protein UL20 homolog (Gene 39 membrane protein)
US03_VZVD Serine/threonine-protein kinase US3 homolog (Protein kinase ORF66) (EC 2.7.11.1)
VP22_VZVD Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
DUT_VZVD Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GI_VZVD Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
IE61_VZVD E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61) (RING-type E3 ...
CEP2_VZVD Cytoplasmic envelopment protein 2
GM_VZVD Envelope glycoprotein M (gM)
DPOL_VZVD DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
DNBI_VZVD Major DNA-binding protein
ITP_VZVD Inner tegument protein
GN_VZVD Envelope glycoprotein N
MCP_VZVD Major capsid protein (MCP)
CEP1_VZVD Cytoplasmic envelopment protein 1
LTP_VZVD Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
GC_VZVD Envelope glycoprotein C (gC) (Glycoprotein V) (gpV)
CVC2_VZVD Capsid vertex component 2
CEP3_VZVD Cytoplasmic envelopment protein 3
GK_VZVD Envelope glycoprotein K (Syncytial protein)
AN_VZVD Alkaline nuclease (EC 3.1.-.-)
HELI_VZVD DNA replication helicase (EC 3.6.4.-)
GH_VZVD Envelope glycoprotein H (gH)
GB_VZVD Envelope glycoprotein B (gB)
GL_VZVD Envelope glycoprotein L (gL)
NEC2_VZVD Nuclear egress protein 2
ORF1_VZVD Structural protein 1 (Structural ORF1 protein)
MB43_VZVD Membrane protein UL43 homolog (Membrane protein ORF15)
KITH_VZVD Thymidine kinase (EC 2.7.1.21)
CVC1_VZVD Capsid vertex component 1
NP03_VZVD Nuclear phosphoprotein UL3 homolog (ORF58 protein)

1 entry

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3) reference strain

ORF0_VZVO Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)

2 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus) reference strain

Select_allDeselect_all
US9_CHV9D Envelope protein US9 homolog (Envelope protein 65) (ORF65 protein)
IE61_CHV9D E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61)

1 entry

Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus) reference strain

GE_CHV1 Envelope glycoprotein E (gE)

47 entries

Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
UL13_EHV1V Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
UL24_EHV1V Protein UL24 homolog
MB43_EHV1V Membrane protein UL43 homolog (Membrane protein ORF17)
CEP1_EHV1V Cytoplasmic envelopment protein 1
ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Infected cell protein 0) (RING-type E3 ubiquitin ...
ICP4_EHV1V Major viral transcription factor ICP4 homolog (155 kDa immediate-early protein)
TEG5_EHV1V Tegument protein UL47 homolog (GP10)
TRM1_EHV1V Tripartite terminase subunit 1
NP04_EHV1V Nuclear protein UL4 homolog
TEG1_EHV1V Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
UNG_EHV1V Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VG75_EHV1V Uncharacterized gene 75 protein
HEPA_EHV1V DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
VG59_EHV1V Uncharacterized gene 59 protein
TEG3_EHV1V Tegument protein UL14 homolog
NEC2_EHV1V Nuclear egress protein 2
PRIM_EHV1V DNA primase (EC 2.7.7.-)
GL_EHV1V Envelope glycoprotein L (gL)
PAP_EHV1V DNA polymerase processivity factor (Polymerase accessory protein) (PAP)
UL20_EHV1V Protein UL20 homolog
US03_EHV1V Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
SHUT_EHV1V Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG4_EHV1V Tegument protein UL21 homolog
VG03_EHV1V Gene 3 protein
VG01_EHV1V Uncharacterized gene 1 protein
TRM3_EHV1V Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TRX1_EHV1V Triplex capsid protein 1
SCAF_EHV1V Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
OBP_EHV1V Replication origin-binding protein (OBP) (OriBP)
SCP_EHV1V Small capsomere-interacting protein
US9_EHV1V Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
US10_EHV1V Virion protein US10 homolog (Gene 66 protein)
GP2_EHV1V Glycoprotein gp2 (Glycoprotein X) (GpX)
DPOL_EHV1V DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
ITP_EHV1V Inner tegument protein
DNBI_EHV1V Major DNA-binding protein
CEP3_EHV1V Cytoplasmic envelopment protein 3
GN_EHV1V Envelope glycoprotein N
CEP2_EHV1V Cytoplasmic envelopment protein 2
GB_EHV1V Envelope glycoprotein B (gB)
CVC2_EHV1V Capsid vertex component 2
AN_EHV1V Alkaline nuclease (EC 3.1.-.-)
NP03_EHV1V Nuclear phosphoprotein UL3 homolog (ORF60 protein)
GG_EHV1V Envelope glycoprotein G (gG)
MCP_EHV1V Major capsid protein (MCP)
PORTL_EHV1V Portal protein
HELI_EHV1V DNA replication helicase (EC 3.6.4.-)

45 entries

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Select_allDeselect_all
TEG1_VZVO Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
TEG6_VZVO Tegument protein UL55 homolog
TYSY_VZVO Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
GI_VZVO Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
ICP22_VZVO Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
ICP27_VZVO mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4)
ICP4_VZVO Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
TEG7_VZVO Tegument protein UL51 homolog (Protein ORF7)
NP03_VZVO Nuclear phosphoprotein UL3 homolog (ORF58 protein)
RIR1_VZVO Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
PAP_VZVO DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
ORF2_VZVO Membrane protein 2 (Membrane ORF2 protein)
TEG5_VZVO Tegument protein UL47 homolog
LTP_VZVO Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
ORF1_VZVO Structural protein 1 (Structural ORF1 protein)
TEG3_VZVO Tegument protein UL14 homolog
OBP_VZVO Replication origin-binding protein (OBP) (OriBP)
GN_VZVO Envelope glycoprotein N
MB43_VZVO Membrane protein UL43 homolog (Membrane protein ORF15)
VP22_VZVO Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
UL13_VZVO Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
TEG4_VZVO Tegument protein UL21 homolog
US9_VZVO Envelope protein US9 (Envelope protein 65) (ORF65 protein)
VP16_VZVO Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
PRIM_VZVO DNA primase (EC 2.7.7.-)
UNG_VZVO Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
RIR2_VZVO Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
UL24_VZVO Protein UL24 homolog
DPOL_VZVO DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
HEPA_VZVO DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
GM_VZVO Envelope glycoprotein M (gM)
DNBI_VZVO Major DNA-binding protein
GL_VZVO Envelope glycoprotein L (gL)
GE_VZVO Envelope glycoprotein E (gE)
CEP3_VZVO Cytoplasmic envelopment protein 3
GH_VZVO Envelope glycoprotein H (gH)
KITH_VZVO Thymidine kinase (EC 2.7.1.21)
GK_VZVO Envelope glycoprotein K (Syncytial protein)
AN_VZVO Alkaline nuclease (EC 3.1.-.-)
DUT_VZVO Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
NP04_VZVO Nuclear protein UL4 homolog (ORF56 protein)
ORF32_VZVO Phosphoprotein 32 (ORF32 Phosphoprotein)
GB_VZVO Envelope glycoprotein B (gB)
ORF57_VZVO Uncharacterized protein 57 (Uncharacterized ORF57 protein)
HELI_VZVO DNA replication helicase (EC 3.6.4.-)

19 entries

Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))

Select_allDeselect_all
ICP22_SUHVK Transcriptional regulator ICP22 homolog (Immediate-early protein RSP40)
ICP27_SUHVK mRNA export factor ICP27 homolog (Protein UL54)
ICP4_SUHVK Major viral transcription factor ICP4 homolog
VNUA_SUHVK Probable nuclear antigen
TEG7_SUHVK Tegument protein UL51
PAP_SUHVK DNA polymerase processivity factor (Polymerase accessory protein) (PAP) (UL42 homolog)
RIR2_SUHVK Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
PRIM_SUHVK DNA primase (EC 2.7.7.-)
KR1_SUHVK Serine/threonine-protein kinase (EC 2.7.11.1)
RIR1_SUHVK Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
SHUT_SUHVK Virion host shutoff protein (Vhs) (EC 3.1.27.-)
SCAF_SUHVK Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
UNG_SUHVK Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GL_SUHVK Envelope glycoprotein L (gL)
GH_SUHVK Envelope glycoprotein H (gH)
DUT_SUHVK Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GN_SUHVK Envelope glycoprotein N
GK_SUHVK Envelope glycoprotein K (Syncytial protein)
GM_SUHVK Envelope glycoprotein M (gM)

17 entries

Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus)

Select_allDeselect_all
TEG1_EHV4 Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
US9_EHV4 Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
RIR1_EHV4 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TEG5_EHV4 Tegument protein UL47 homolog (GP10)
US10_EHV4 Virion protein US10 homolog (ORF3)
TEG7_EHV4 Tegument protein UL51 homolog
UL24_EHV4 Protein UL24 homolog
RIR2_EHV4 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
VP16_EHV4 Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
VP22_EHV4 Tegument protein VP22 (Gene 11 protein)
GC_EHV4 Envelope glycoprotein C (Glycoprotein 13)
GG_EHV4 Envelope glycoprotein G (gG)
EV45_EHV4 Envelope protein UL45 homolog
DUT_EHV4 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GB_EHV4 Envelope glycoprotein B (gB)
KITH_EHV4 Thymidine kinase (EC 2.7.1.21)
GH_EHV4 Envelope glycoprotein H (gH)

15 entries

Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
TEG1_HHV1F Tegument protein UL46 (Tegument protein VP11/12)
ICP34_HHV1F Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
TEG5_HHV1F Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
US10_HHV1F Virion protein US10
NP03_HHV1F Nuclear phosphoprotein UL3
LRP2_HHV1F Latency-related protein 2
US8A_HHV1F US8.5 protein
TRM1_HHV1F Tripartite terminase subunit 1
VP16_HHV1F Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
GH_HHV1F Envelope glycoprotein H (gH)
GD_HHV1F Envelope glycoprotein D (gD)
GB_HHV1F Envelope glycoprotein B (gB)
GE_HHV1F Envelope glycoprotein E (gE) (gE-1)
LRP1_HHV1F Latency-related protein 1
DNBI_HHV1F Major DNA-binding protein

14 entries

Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
GB_BHV1C Envelope glycoprotein B (gB)
GN_BHV1C Envelope glycoprotein N
SCAF_BHV1C Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
RIR1_BHV1C Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
RIR2_BHV1C Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
GM_BHV1C Envelope glycoprotein M (gM)
TEG5_BHV1C Tegument protein UL47
UNG_BHV1C Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
OBP_BHV1C Replication origin-binding protein (OriBP) (OBP)
VP22_BHV1C Tegument protein VP22
GC_BHV1C Envelope glycoprotein C homolog (Glycoprotein GIII)
HEPA_BHV1C DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
GH_BHV1C Envelope glycoprotein H (gH)
GD_BHV1C Envelope glycoprotein D (gD) (Glycoprotein IV)

14 entries

Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
US02_EHV1K US1 protein
ICP22_EHV1K Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
ICP27_EHV1K mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
ICP4_EHV1K Major viral transcription factor (155 kDa immediate-early protein)
TEG6_EHV1K Tegument protein UL55 homolog
US10_EHV1K Virion protein US10 homolog (Gene 66 protein) (IR5 protein) (ORF S2-1)
VG67_EHV1K Uncharacterized gene 67 protein (IR6 protein)
KR1_EHV1K Serine/threonine-protein kinase (EC 2.7.11.1)
VG03_EHV1K Gene 3 protein (ORF L1)
US9_EHV1K Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
GP2_EHV1K Glycoprotein gp2 (Glycoprotein X) (GpX)
GG_EHV1K Envelope glycoprotein G (gG)
GK_EHV1K Envelope glycoprotein K (Syncytial protein)
GD_EHV1K Envelope glycoprotein D (gD) (Glycoprotein 17/18)

12 entries

Gallid herpesvirus 2 (strain GA) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
US384_GAHVG Uncharacterized 14.2 kDa protein
ICP4_GAHVG Major viral transcription factor ICP4 homolog (Immediate-early protein IE175)
US453_GAHVG Uncharacterized 16.6 kDa protein
US10_GAHVG Virion protein US10 homolog
U1053_GAHVG Uncharacterized 40.6 kDa protein
US426_GAHVG Uncharacterized 15.7 kDa protein
US441_GAHVG Uncharacterized 16.7 kDa protein
US420_GAHVG Uncharacterized 15.5 kDa protein
US03_GAHVG Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
VP38_GAHVG 38 kDa phosphoprotein (Phosphoprotein pp38)
GC_GAHVG Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)
GL_GAHVG Envelope glycoprotein L (gL)

12 entries

Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
EV45_HHV1K Envelope protein UL45 (18 kDa protein)
RIR2_HHV1K Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SHUT_HHV1K Virion host shutoff protein (Vhs) (EC 3.1.27.-)
KITH_HHV1K Thymidine kinase (EC 2.7.1.21)
GK_HHV1K Envelope glycoprotein K (Syncytial protein)
GD_HHV1K Envelope glycoprotein D (gD)
DPOL_HHV1K DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
DNBI_HHV1K Major DNA-binding protein
GL_HHV1K Envelope glycoprotein L (gL)
CEP3_HHV1K Cytoplasmic envelopment protein 3
GC_HHV1K Envelope glycoprotein C
GB_HHV1K Envelope glycoprotein B (gB)

12 entries

Human herpesvirus 2 (strain 333) (HHV-2) (Human herpes simplex virus 2)

Select_allDeselect_all
RIR2_HHV23 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
VP16_HHV23 Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
RIR1_HHV23 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
KITH_HHV23 Thymidine kinase (EC 2.7.1.21)
NP03_HHV23 Nuclear phosphoprotein UL3
UNG_HHV23 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
SHUT_HHV23 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
GI_HHV23 Envelope glycoprotein I (gI)
GD_HHV23 Envelope glycoprotein D (gD)
GC_HHV23 Envelope glycoprotein C
EV45_HHV23 Envelope protein UL45 (18 kDa protein)
GB_HHV23 Envelope glycoprotein B (gB)

8 entries

Bovine herpesvirus 1.2 (strain ST) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
US9_BHV1S Envelope protein US9
US02_BHV1S Protein US2 homolog
VGLX_BHV1S Glycoprotein GX
YOR1_BHV1S Uncharacterized 16.1 kDa protein (ORF1)
US03_BHV1S Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
GD_BHV1S Envelope glycoprotein D (gD) (Glycoprotein IV)
GE_BHV1S Envelope glycoprotein E (gE)
GI_BHV1S Envelope glycoprotein I (gI)

8 entries

Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker) (SuHV-1) (Pseudorabies virus (strain Indiana-Funkhauser / Becker))

Select_allDeselect_all
ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Early protein 0) (EP0) (RING-type E3 ubiquitin ...
ICP4_SUHVF Major viral transcription factor ICP4 homolog
GL_SUHVF Envelope glycoprotein L (gL)
UNG_SUHVF Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TRM1_SUHVF Tripartite terminase subunit 1
GB_SUHVF Envelope glycoprotein B (gB)
GC_SUHVF Envelope glycoprotein C homolog (Glycoprotein GIII)
DNBI_SUHVF Major DNA-binding protein

8 entries

Suid herpesvirus 1 (strain NIA-3) (SuHV-1) (Pseudorabies virus (strain NIA-3))

Select_allDeselect_all
TEG4_SUHVN Tegument protein UL21
US03_SUHVN Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
US02_SUHVN Protein US2 homolog (28 kDa protein)
UL13_SUHVN Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
TEG3_SUHVN Tegument protein UL14
UL20_SUHVN Protein UL20
GH_SUHVN Envelope glycoprotein H (gH)
KITH_SUHVN Thymidine kinase (EC 2.7.1.21)

6 entries

Equine herpesvirus 1 (strain Kentucky D) (EHV-1) (Equine abortion virus)

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GI_EHV1D Envelope glycoprotein I (gI)
GD_EHV1D Envelope glycoprotein D (gD) (Glycoprotein 17/18)
EV45_EHV1D Envelope protein UL45 homolog
GC_EHV1D Envelope glycoprotein C (gC) (Glycoprotein 13)
GB_EHV1D Envelope glycoprotein B (gB)
GE_EHV1D Envelope glycoprotein E (gE)

6 entries

Human herpesvirus 1 (strain HFEM) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
UL56_HHV1E Protein UL56
ICP27_HHV1E mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27)
KITH_HHV1E Thymidine kinase (EC 2.7.1.21)
TEG6_HHV1E Tegument protein UL55
TEG4_HHV1E Tegument protein UL21
GH_HHV1E Envelope glycoprotein H (gH)

6 entries

Suid herpesvirus 1 (strain Rice) (SuHV-1) (Pseudorabies virus (strain Rice))

Select_allDeselect_all
US9_SUHVR Envelope protein US9 homolog (11 kDa protein)
GE_SUHVR Envelope glycoprotein E (gE)
GD_SUHVR Envelope glycoprotein D (gD) (Protein gp50)
GG_SUHVR Envelope glycoprotein G (gG)
GH_SUHVR Envelope glycoprotein H (gH)
GI_SUHVR Envelope glycoprotein I (Glycoprotein GP63)

3 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus)

Select_allDeselect_all
US03_CHV9D Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
GE_CHV9D Envelope glycoprotein E (Membrane glycoprotein 2) (gE)
GI_CHV9D Envelope glycoprotein I (Membrane glycoprotein 1)

5 entries

Equine herpesvirus 1 (strain AB1) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
UL32_EHV1A Packaging protein UL32 homolog (Glycoprotein 300) (GP300)
GB_EHV1A Envelope glycoprotein B (gB)
GD_EHV1A Envelope glycoprotein D (gD) (Glycoprotein 17/18)
GE_EHV1A Envelope glycoprotein E (gE)
GI_EHV1A Envelope glycoprotein I

5 entries

Equine herpesvirus 1 (strain HVS25A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
GH_EHV1 Envelope glycoprotein H (gH)
KITH_EHV1 Thymidine kinase (EC 2.7.1.21)
TRM1_EHV1 Tripartite terminase subunit 1
UL24_EHV1 Protein UL24 homolog
GB_EHV1 Envelope glycoprotein B (gB)

5 entries

Infectious laryngotracheitis virus (strain Thorne V882) (ILTV) (Gallid herpesvirus 1)

Select_allDeselect_all
UL24_ILTVT Protein UL24 homolog (ORF 3)
KITH_ILTVT Thymidine kinase (EC 2.7.1.21)
SCAF_ILTVT Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
GB_ILTVT Envelope glycoprotein B (gB)
CVC2_ILTVT Capsid vertex component 2

4 entries

Bovine herpesvirus 1.1 (strain P8-2) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
TEG5_BHV1P Tegument protein UL47
VP16_BHV1P Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
GB_BHV1P Envelope glycoprotein B (gB)
GD_BHV1P Envelope glycoprotein D (gD) (Glycoprotein IV)

3 entries

Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus)

Select_allDeselect_all
VGLJ_CHV1 Envelope glycoprotein J
US9_CHV1 Envelope protein US9 homolog (10 kDa protein)
GD_CHV1 Envelope glycoprotein D (gD)

4 entries

Gallid herpesvirus 2 (strain RB-1b) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
GH_GAHVR Envelope glycoprotein H (gH)
GB_GAHVR Envelope glycoprotein B (gB)
KITH_GAHVR Thymidine kinase (EC 2.7.1.21)
GC_GAHVR Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)

3 entries

Bovine herpesvirus 2 (strain BMV) (BoHV-2) (Bovine mammillitis virus)

Select_allDeselect_all
TRM1_BHV2B Tripartite terminase subunit 1
GB_BHV2B Envelope glycoprotein B (gB)
DNBI_BHV2B Major DNA-binding protein

3 entries

Human herpesvirus 1 (strain Angelotti) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
TRM1_HHV1A Tripartite terminase subunit 1
DPOL_HHV1A DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GD_HHV1A Envelope glycoprotein D (gD)

3 entries

Human herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
RNB_HHV1M RNA-binding protein (Vmw21)
EV45_HHV1M Envelope protein UL45 (18 kDa protein)
GK_HHV1M Envelope glycoprotein K (Syncytial protein)

3 entries

Human herpesvirus 2 (strain G) (HHV-2) (Human herpes simplex virus 2)

Select_allDeselect_all
TRX1_HHV2G Triplex capsid protein 1
SHUT_HHV2G Virion host shutoff protein (Vhs) (EC 3.1.27.-)
GC_HHV2G Envelope glycoprotein C (Glycoprotein F)

2 entries

Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)

Select_allDeselect_all
KITH_FHV1 Thymidine kinase (EC 2.7.1.21)
GH_FHV1 Envelope glycoprotein H (gH)

2 entries

Gallid herpesvirus 2 (strain bc-1) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
EV45_GAHVB Envelope protein UL45 homolog
GC_GAHVB Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)

2 entries

Herpes simplex virus type 2 (strain SA8) (Simian agent 8)

Select_allDeselect_all
ICP47_HSV2S ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...
GB_HSV2S Envelope glycoprotein B (gB)

2 entries

Human herpesvirus 1 (strain Patton) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
GB_HHV1P Envelope glycoprotein B (gB)
GD_HHV1P Envelope glycoprotein D (gD)

2 entries

Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
KITH_HHV1S Thymidine kinase (EC 2.7.1.21)
DPOL_HHV1S DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)

2 entries

Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2)

Select_allDeselect_all
DNBI_HHV2 Major DNA-binding protein
AN_HHV2 Alkaline nuclease (EC 3.1.-.-)

2 entries

Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
KITH_MEHV1 Thymidine kinase (EC 2.7.1.21)
GH_MEHV1 Envelope glycoprotein H (gH)

2 entries

Meleagrid herpesvirus 1 (strain FC126) (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
GC_MEHVF Envelope glycoprotein C homolog (A antigen) (Glycoprotein A)
KITH_MEHVF Thymidine kinase (EC 2.7.1.21)

2 entries

Meleagrid herpesvirus 1 (strain H2) (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
EV45_MEHVH Envelope protein UL45 homolog (23.5 kDa protein)
GC_MEHVH Envelope glycoprotein C homolog (A antigen) (Glycoprotein A)

2 entries

Saimiriine herpesvirus 1 (strain MV-5-4-PSL) (SaHV-1) (Marmoset herpesvirus)

Select_allDeselect_all
KITH_SHV1 Thymidine kinase (EC 2.7.1.21)
GB_SHV1 Envelope glycoprotein B (gB)

1 entry

Bovine herpesvirus 1 (strain 6660) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV16 Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 1.1 (strain Jura) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1J E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain K22) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain Q3932) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV1Q Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 2 (strain BHM-1) (BoHV-2) (Bovine mammillitis virus)

KITH_BHV2H Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 5 (strain N569) (BoHV-5) (Bovine encephalitis herpesvirus)

KITH_BHV5 Thymidine kinase (EC 2.7.1.21)

1 entry

Cercopithecine herpesvirus 1 (strain E2490) (CeHV-1) (Simian herpes B virus)

ICP47_CHV1E ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...

1 entry

Cercopithecine herpesvirus 16 (CeHV-16) (Herpesvirus papio 2)

ICP47_CHV16 ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...

1 entry

Equine herpesvirus 1 (strain HH1) (EHV-1) (Equine abortion virus)

VG01_EHV1H Uncharacterized gene 1 protein

1 entry

Gallid herpesvirus 2 (strain MD11/75C/R2) (GaHV-2) (Marek's disease herpesvirus type 1)

VP38_GAHVN 38 kDa phosphoprotein (Phosphoprotein pp38)

1 entry

Herpesvirus ateles type 1 (strain Lennette)

GB_HSVA1 Envelope glycoprotein B (gB)

1 entry

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)

KITH_HHV1 Thymidine kinase (EC 2.7.1.21)

1 entry

Human herpesvirus 1 (strain A44) (HHV-1) (Human herpes simplex virus 1)

TRX1_HHV14 Triplex capsid protein 1

1 entry

Human herpesvirus 1 (strain CL101) (HHV-1) (Human herpes simplex virus 1)

KITH_HHV1C Thymidine kinase (EC 2.7.1.21)

1 entry

Human herpesvirus 1 (strain CVG-2) (HHV-1) (Human herpes simplex virus 1)

ICP34_HHV1D Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)

1 entry

Human herpesvirus 1 (strain HZT) (HHV-1) (Human herpes simplex virus 1)

GD_HHV1H Envelope glycoprotein D (gD)

1 entry

Human herpesvirus 1 (strain MGH-10) (HHV-1) (Human herpes simplex virus 1)

ICP34_HHV1N Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)

1 entry

Human herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1)

GK_HHV1R Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain R19) (HHV-1) (Human herpes simplex virus 1)

GK_HHV19 Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 2 (strain 186) (HHV-2) (Human herpes simplex virus 2)

DPOL_HHV21 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)

1 entry

Human herpesvirus 2 (strain B4327UR) (HHV-2) (Human herpes simplex virus 2)

GG_HHV2B Envelope glycoprotein G (gG) (gG-2)

1 entry

Infectious laryngotracheitis virus (strain 632) (ILTV) (Gallid herpesvirus 1)

GB_ILTV6 Envelope glycoprotein B (gB)

1 entry

Infectious laryngotracheitis virus (strain SA-2) (ILTV) (Gallid herpesvirus 1)

GB_ILTVS Envelope glycoprotein B (gB)

1 entry

Suid herpesvirus 1 (strain Indiana S) (SuHV-1) (Pseudorabies virus (strain Indiana S))

MCP_SUHVS Major capsid protein (MCP)