Alphaherpesvirinae

VIRION

image

Enveloped, spherical to pleomorphic, 150-200 nm in diameter, T=16 icosahedral symmetry. The capsid consists of 162 capsomers and is surrounded by an amorphous tegument. Glycoproteins complexes are embedded in the lipid envelope.

GENOME

Monopartite, linear, dsDNA genome of 120-180 kb. The genome contains terminal and internal reiterated sequences.

GENE EXPRESSION

Each viral transcript usually encodes a single protein and has a promoter/regulatory sequence, a TATA box, a transcription initiation site, a 5' leader sequence of 30-300 bp (not translated), a 3' nontranslated sequence of 10-30 bp, and a poly A signal. There are many gene overlaps. There are only few spliced genes. Some of the expressed ORFs are antisense to each other. Some ORFs can be accessed from more than one promoter. There are some non-coding genes.

There are three types of genes: immediate-early (?), early(?) and late (?). The ? genes are transcribed immediately after infection and ensure the transcription of ? genes, which encode the proteins necessary for the viral replication. The ? genes mostly encode structural proteins. Standing apart are genes expressed during latency.

The viral proteins VHS and ICP27 are involved in shut-off of host protein translation in order to ensure the selective expression of viral proteins versus cellular proteins.

REPLICATION

NUCLEAR

Lytic replication:

  1. Attachment of the viral gB, gC, gD and gH proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the core and the tegument proteins into the host cytoplasm.
  3. The capsid is transported to the nuclear pore where viral DNA is released into the nucleus.
  4. Transcription of immediate early genes which promote transcription of early genes and protect the virus against innate host immunity.
  5. Transcription of early viral mRNA by host polymerase II, encoding proteins involved in replication of the viral DNA.
  6. A first round of circular genome amplification occurs by bidirectional replication
  7. Synthesis of linear concatemer copies of viral DNA by rolling circle.
  8. Transcription of late mRNAs by host polymerase II, encoding structural proteins.
  9. Assembly of the virus in nuclear viral factories and budding through the inner lamella of the nuclear membrane which has been modified by the insertion of herpes glycoproteins, throughout the Golgi and final release at the plasma membrane.

Latent replication : replication of circular viral episome in tandem with the host cell DNA using the host cell replication machinery.

Host-virus interaction

Adaptive immune response inhibition

Alpha-herpesviruses have evolved different strategies to inhibit the host adaptive immune response. For example, Herpes simplex protein US12 binds specifically to transporters associated with antigen processing (TAP), blocking peptide-binding to TAP and subsequent loading of peptides onto MHC class I molecules . VZV ORF66 downregulates MHC I expression by impairing the transport of MHC I molecules from the Golgi compartment to the cell surface

Apoptosis modulation

Apoptosis is very often modulated (and usually inhibited) by alpha-herpesviruses. Herpes virus simplex protein US3 activates host protein kinase A/PKA to block apoptosis. Additionally, it also interacts with programmed cell death protein 4 (PDCD4) and retains it in the nucleus thereby inhibiting host apoptosis .

Autophagy modulation

Several alpha-herpesviruses are able to inhibit host cell autophagy process, such as HHV-1 ICP34.5 that interacts with Beclin-1 and stop autophagosomes development .

Cell-cycle modulation

The UL24 protein that is present in all herpesvirus subfamilies (alpha, beta and gamma-herpesviruses) induces a cell cycle arrest at G2/M transition through inactivation of the host cyclinB/cdc2 complex .

Innate immune response inhibition

Herpes viruses inhibit the cascade leading to production of interferon-beta by mainly targeting the host IRF3 protein. Thus, herpes simplex virus or varicella virus possess proteins to prevent IRF3 activation.

Host splicing inhibition

HSV-1 ICP27 is an alternative splicing regulator of host mRNA. This protein is conserved in several herpesviridae genera. It has been shown to act as a splicing silencer at the 3' splice site of the PML intron 7a .

Matching UniProtKB/Swiss-Prot entries

788 entries grouped by strain (browse by keywords)

90 entries

Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

Select_allDeselect_all
RIR1_GAHVM Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
PP24_GAHVM Phosphoprotein pp24
SCAF_GAHVM Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
TEG3_GAHVM Tegument protein UL14 homolog
TRM2_GAHVM Tripartite terminase subunit 2
TEG1_GAHVM Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
TEG7_GAHVM Tegument protein UL51 homolog
UL24_GAHVM Protein UL24 homolog
VG85_GAHVM Uncharacterized gene 85 protein
SHUT_GAHVM Virion host shutoff protein (Vhs) (EC 3.1.27.-)
US10_GAHVM Virion protein US10 homolog
NEC2_GAHVM Nuclear egress protein 2
ITP_GAHVM Inner tegument protein
OBP_GAHVM Replication origin-binding protein (OBP) (OriBP)
MEQ_GAHVM Oncoprotein MEQ (MEQ)
PAP_GAHVM DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
NP03_GAHVM Nuclear phosphoprotein UL3 homolog
IL8H_GAHVM Viral interleukin-8 homolog (vIL8)
VG01_GAHVM Uncharacterized gene 1 protein
VG02_GAHVM Uncharacterized gene 2 protein
TEG6_GAHVM Tegument protein UL55 homolog
VG72_GAHVM Uncharacterized gene 72 protein
VG71_GAHVM Uncharacterized gene 71 protein
US02_GAHVM Protein US2 homolog
US03_GAHVM Protein kinase US3 homolog (EC 2.7.11.1)
VLIP_GAHVM Virulence factor MDV010 (Viral lipase homolog) (vLIP)
VG06A_GAHVM Uncharacterized gene 6a protein
TRX2_GAHVM Triplex capsid protein 2
VG04_GAHVM Uncharacterized gene 4 protein
KITH_GAHVM Thymidine kinase (EC 2.7.1.21)
UL13_GAHVM Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
PP38_GAHVM Phosphoprotein pp38
UNG_GAHVM Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VG86_GAHVM Uncharacterized gene 86 protein
TRX1_GAHVM Triplex capsid protein 1
SCP_GAHVM Small capsomere-interacting protein
RIR2_GAHVM Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
GB_GAHVM Envelope glycoprotein B (gB)
DPOL_GAHVM DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
CEP1_GAHVM Cytoplasmic envelopment protein 1
DNBI_GAHVM Major DNA-binding protein
CEP2_GAHVM Cytoplasmic envelopment protein 2
HEPA_GAHVM DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
EV45_GAHVM Envelope protein UL45 homolog
GD_GAHVM Envelope glycoprotein D (gD)
GC_GAHVM Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)
ICP4_GAHVM Major viral transcription factor ICP4 homolog (Immediate-early protein IE175)
CVC1_GAHVM Capsid vertex component 1
AN_GAHVM Alkaline nuclease (EC 3.1.-.-)
GH_GAHVM Envelope glycoprotein H (gH)
GL_GAHVM Envelope glycoprotein L (gL)
GI_GAHVM Envelope glycoprotein I
ICP22_GAHVM Transcriptional regulator ICP22 homolog (Immediate early ICP22-like protein)
GE_GAHVM Envelope glycoprotein E (gE)
HELI_GAHVM DNA replication helicase (EC 3.6.4.-)
MCP_GAHVM Major capsid protein (MCP)
GK_GAHVM Envelope glycoprotein K
LTP_GAHVM Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
ICP27_GAHVM mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
NEC1_GAHVM Nuclear egress protein 1
GM_GAHVM Envelope glycoprotein M (gM)
PORTL_GAHVM Portal protein
MB43_GAHVM Membrane protein UL43 homolog
UL32_GAHVM Packaging protein UL32 homolog
VG69_GAHVM Uncharacterized gene 69 protein
VG82_GAHVM Uncharacterized gene 82 protein
VG81_GAHVM Uncharacterized gene 81 protein
DUT_GAHVM Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
VG90_GAHVM Uncharacterized gene 90 protein
VG97_GAHVM Uncharacterized gene 97 protein
VP22_GAHVM Tegument protein VP22
TG21_GAHVM Tegument protein UL21 homolog
TEG5_GAHVM Tegument protein UL47 homolog
VP16_GAHVM Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
VG12_GAHVM Uncharacterized gene 12 protein
VG07_GAHVM Uncharacterized gene 7 protein
UL4_GAHVM Nuclear protein UL4 homolog
UL20_GAHVM Protein UL20 homolog
VG11_GAHVM Uncharacterized gene 11 protein
VG06B_GAHVM Uncharacterized gene 6b protein
VG83_GAHVM Uncharacterized gene 83 protein
PRIM_GAHVM DNA primase (EC 2.7.7.-)
TRM3_GAHVM Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TRM1_GAHVM Tripartite terminase subunit 1
VG87_GAHVM Uncharacterized gene 87 protein
VG09_GAHVM Uncharacterized gene 9 protein
VG93_GAHVM Uncharacterized gene 93 protein
CEP3_GAHVM Cytoplasmic envelopment protein 3
CVC2_GAHVM Capsid vertex component 2
GN_GAHVM Envelope glycoprotein N

75 entries

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

Select_allDeselect_all
PRIM_EHV1B DNA primase (EC 2.7.7.-)
TEG4_EHV1B Tegument protein UL21 homolog
TEG1_EHV1B Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
TEG5_EHV1B Tegument protein UL47 homolog (GP10)
SCAF_EHV1B Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural gene ...
SHUT_EHV1B Virion host shutoff protein (Vhs) (EC 3.1.27.-)
NP03_EHV1B Nuclear phosphoprotein UL3 homolog (ORF60 protein)
RIR2_EHV1B Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TRM1_EHV1B Tripartite terminase subunit 1
UL32_EHV1B Packaging protein UL32 homolog
SCP_EHV1B Small capsomere-interacting protein
TRM3_EHV1B Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
NEC2_EHV1B Nuclear egress protein 2
VG02_EHV1B Uncharacterized gene 2 protein
HEPA_EHV1B DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
ITP_EHV1B Inner tegument protein
KITH_EHV1B Thymidine kinase (EC 2.7.1.21)
OBP_EHV1B Replication origin-binding protein (OriBP) (OBP)
UL13_EHV1B Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
TEG3_EHV1B Tegument protein UL14 homolog
US02_EHV1B Gene 68 protein
UL24_EHV1B Protein UL24 homolog
VG75_EHV1B Uncharacterized gene 75 protein
RIR1_EHV1B Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
US10_EHV1B Virion protein US10 homolog (Gene 66 protein)
TRX2_EHV1B Triplex capsid protein 2
TEG7_EHV1B Tegument protein UL51 homolog
TRX1_EHV1B Triplex capsid protein 1
TRM2_EHV1B Tripartite terminase subunit 2
GK_EHV1B Envelope glycoprotein K (Syncytial protein)
GG_EHV1B Envelope glycoprotein G (gG)
ICP22_EHV1B Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
GH_EHV1B Envelope glycoprotein H (gH)
CEP3_EHV1B Cytoplasmic envelopment protein 3
CEP1_EHV1B Cytoplasmic envelopment protein 1
CVC1_EHV1B Capsid vertex component 1
CVC2_EHV1B Capsid vertex component 2
GI_EHV1B Envelope glycoprotein I
GL_EHV1B Envelope glycoprotein L (gL)
GD_EHV1B Envelope glycoprotein D (gD) (Glycoprotein 17/18)
EV45_EHV1B Envelope protein UL45 homolog
GC_EHV1B Envelope glycoprotein C (gC) (Glycoprotein 13)
DPOL_EHV1B DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
DNBI_EHV1B Major DNA-binding protein
AN_EHV1B Alkaline nuclease (EC 3.1.-.-)
CEP2_EHV1B Cytoplasmic envelopment protein 2
GE_EHV1B Envelope glycoprotein E (gE)
GN_EHV1B Envelope glycoprotein N
GM_EHV1B Envelope glycoprotein M (gM)
ICP4_EHV1B Major viral transcription factor (155 kDa immediate-early protein)
MB43_EHV1B Membrane protein UL43 homolog (Membrane protein ORF17)
LTP_EHV1B Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
GB_EHV1B Envelope glycoprotein B (gB)
GP2_EHV1B Glycoprotein gp2 (Glycoprotein X) (GpX)
MCP_EHV1B Major capsid protein (MCP)
ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ICP0)
NEC1_EHV1B Nuclear egress protein 1
ICP27_EHV1B mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
PAP_EHV1B DNA polymerase processivity factor (DNA-binding gene 18 protein) (Polymerase accessory protein) ...
PORTL_EHV1B Portal protein
HELI_EHV1B DNA replication helicase (EC 3.6.4.-)
UNG_EHV1B Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VG34_EHV1B Gene 34 protein
VG67_EHV1B Uncharacterized gene 67 protein (IR6 protein)
UL20_EHV1B Protein UL20 homolog
US9_EHV1B Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
TEG6_EHV1B Tegument protein UL55 homolog
VG01_EHV1B Uncharacterized gene 1 protein
VG03_EHV1B Gene 3 protein
US03_EHV1B Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
VG59_EHV1B Uncharacterized gene 59 protein
VP22_EHV1B Tegument protein VP22 (Gene 11 protein)
NP04_EHV1B Nuclear protein UL4 homolog
VP16_EHV1B Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
DUT_EHV1B Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)

73 entries

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

Select_allDeselect_all
SCAF_HHV11 Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
SCP_HHV11 Small capsomere-interacting protein
TRM1_HHV11 Tripartite terminase subunit 1
EV45_HHV11 Envelope protein UL45 (18 kDa protein)
SHUT_HHV11 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
US02_HHV11 Protein US2
TEG5_HHV11 Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
RNB_HHV11 Accessory factor US11 (Vmw21)
TRX2_HHV11 Triplex capsid protein 2
ICP22_HHV11 Transcriptional regulator ICP22 (Immediate-early protein IE68) (Infected cell protein 22) (ICP22)
NEC1_HHV11 Nuclear egress protein 1
MB43_HHV11 Membrane protein UL43
OBP_HHV11 Replication origin-binding protein (OBP) (OriBP)
NP04_HHV11 Nuclear protein UL4
MCP_HHV11 Major capsid protein (MCP)
PAP_HHV11 DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
PRIM_HHV11 DNA primase (EC 2.7.7.-)
RIR2_HHV11 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TEG4_HHV11 Tegument protein UL21
TEG1_HHV11 Tegument protein UL46 (Tegument protein VP11/12)
UL13_HHV11 Serine/threonine-protein kinase UL13 (EC 2.7.11.1) (Virion protein VMW57)
US03_HHV11 Serine/threonine-protein kinase US3 (EC 2.7.11.1)
UL56_HHV11 Protein UL56
NP03_HHV11 Nuclear phosphoprotein UL3
TRX1_HHV11 Triplex capsid protein 1
UL20_HHV11 Protein UL20
RIR1_HHV11 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
GB_HHV11 Envelope glycoprotein B (gB)
DUT_HHV11 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
DNBI_HHV11 Major DNA-binding protein
CEP2_HHV11 Cytoplasmic envelopment protein 2
HELI_HHV11 DNA replication helicase (EC 3.6.4.-)
ICP47_HHV11 ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...
GL_HHV11 Envelope glycoprotein L (gL)
CEP3_HHV11 Cytoplasmic envelopment protein 3
DPOL_HHV11 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
CEP1_HHV11 Cytoplasmic envelopment protein 1
CVC1_HHV11 Capsid vertex component 1
CVC2_HHV11 Capsid vertex component 2
AN_HHV11 Alkaline nuclease (EC 3.1.-.-)
GD_HHV11 Envelope glycoprotein D (gD)
GI_HHV11 Envelope glycoprotein I (gI)
ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Alpha-0 protein) (Immediate-early protein IE110) ...
GM_HHV11 Envelope glycoprotein M (gM)
GG_HHV11 Envelope glycoprotein G (gG) (gG-1)
GJ_HHV11 Envelope glycoprotein J
GE_HHV11 Envelope glycoprotein E (gE) (gE-1)
GH_HHV11 Envelope glycoprotein H (gH)
GK_HHV11 Envelope glycoprotein K (Syncytial protein)
LTP_HHV11 Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
ICP34_HHV11 Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
HEPA_HHV11 DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
KITH_HHV11 Thymidine kinase (EC 2.7.1.21)
ICP4_HHV11 Major viral transcription factor ICP4 (Alpha-4 protein) (Infected cell protein 4) (Transcriptional ...
NEC2_HHV11 Nuclear egress protein 2
GC_HHV11 Envelope glycoprotein C
ICP27_HHV11 mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)
ITP_HHV11 Inner tegument protein (EC 3.5.1.-) (EC 3.5.1.44) (Viral deamidase UL37)
TEG6_HHV11 Tegument protein UL55
TRM2_HHV11 Tripartite terminase subunit 2
TEG3_HHV11 Tegument protein UL14
TRM3_HHV11 Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
US10_HHV11 Virion protein US10
UNG_HHV11 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VP16_HHV11 Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
UL24_HHV11 Protein UL24
PORTL_HHV11 Portal protein
US8A_HHV11 Protein US8.5
UL32_HHV11 Packaging protein UL32
TEG7_HHV11 Tegument protein UL51
US9_HHV11 Envelope protein US9 (10 kDa protein)
VP22_HHV11 Tegument protein VP22
GN_HHV11 Envelope glycoprotein N

72 entries

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

Select_allDeselect_all
SHUT_HHV2H Virion host shutoff protein (Vhs) (EC 3.1.27.-)
GJ_HHV2H Envelope glycoprotein J
TEG5_HHV2H Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
TEG1_HHV2H Tegument protein UL46 (Tegument protein VP11/12)
PRIM_HHV2H DNA primase (EC 2.7.7.-)
UL56_HHV2H Protein UL56
UL20_HHV2H Protein UL20
SCAF_HHV2H Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
NEC2_HHV2H Nuclear egress protein 2
PAP_HHV2H DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
RNB_HHV2H Probable RNA-binding protein
SCP_HHV2H Small capsomere-interacting protein
ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferaseICP0) (VMW118 ...
NEC1_HHV2H Nuclear egress protein 1
LTP_HHV2H Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
RIR1_HHV2H Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
UL24_HHV2H Protein UL24
TEG3_HHV2H Tegument protein UL14
TRM1_HHV2H Tripartite terminase subunit 1
VP16_HHV2H Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
GL_HHV2H Envelope glycoprotein L (gL)
VP22_HHV2H Tegument protein VP22
RIR2_HHV2H Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
HELI_HHV2H DNA replication helicase (EC 3.6.4.-)
GI_HHV2H Envelope glycoprotein I (gI)
CEP2_HHV2H Cytoplasmic envelopment protein 2
ICP4_HHV2H Major viral transcription factor ICP4 homolog (Alpha-4 protein) (Infected cell protein 4) ...
DUT_HHV2H Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
CVC1_HHV2H Capsid vertex component 1
CVC2_HHV2H Capsid vertex component 2
CEP3_HHV2H Cytoplasmic envelopment protein 3
GB_HHV2H Envelope glycoprotein B (gB)
CEP1_HHV2H Cytoplasmic envelopment protein 1
DPOL_HHV2H DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
DNBI_HHV2H Major DNA-binding protein
ICP22_HHV2H E3 ubiquitin ligase ICP22 (Immediate-early protein IE68) (Infected cell protein 22) (ICP22)
GM_HHV2H Envelope glycoprotein M (gM)
GG_HHV2H Envelope glycoprotein G (gG) (gG-2)
GK_HHV2H Envelope glycoprotein K (Syncytial protein)
GH_HHV2H Envelope glycoprotein H (gH)
GD_HHV2H Envelope glycoprotein D (gD)
GC_HHV2H Envelope glycoprotein C
ICP27_HHV2H mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)
KITH_HHV2H Thymidine kinase (EC 2.7.1.21)
ITP_HHV2H Inner tegument protein
EV45_HHV2H Envelope protein UL45 (18 kDa protein)
MCP_HHV2H Major capsid protein (MCP)
GE_HHV2H Envelope glycoprotein E (gE) (gE-2)
ICP34_HHV2H Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
ICP47_HHV2H ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...
NP04_HHV2H Nuclear protein UL4
NP03_HHV2H Nuclear phosphoprotein UL3
HEPA_HHV2H DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
TEG6_HHV2H Tegument protein UL55
TRM3_HHV2H Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
UL13_HHV2H Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
TRX1_HHV2H Triplex capsid protein 1
US9_HHV2H Envelope protein US9 (10 kDa protein)
TRM2_HHV2H Tripartite terminase subunit 2
TEG7_HHV2H Tegument protein UL51
UL32_HHV2H Packaging protein UL32
US10_HHV2H Virion protein US10
TEG4_HHV2H Tegument protein UL21
US03_HHV2H Serine/threonine-protein kinase US3 (EC 2.7.11.1)
TRX2_HHV2H Triplex capsid protein 2
PORTL_HHV2H Portal protein
OBP_HHV2H Replication origin-binding protein (OBP) (OriBP)
MB43_HHV2H Membrane protein UL43
US8A_HHV2H Protein US8.5
US02_HHV2H Protein US2
UNG_HHV2H Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GN_HHV2H Envelope glycoprotein N

71 entries

Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain

Select_allDeselect_all
TRM3_PSHV1 Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
SCAF_PSHV1 Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
PRIM_PSHV1 DNA primase (EC 2.7.7.-)
UL15B_PSHV1 Large terminase protein homolog UL15b
TEG7_PSHV1 Tegument protein UL51
VP22_PSHV1 Tegument protein VP22
TG21_PSHV1 Tegument protein UL21
TRM2_PSHV1 Tripartite terminase subunit 2
US03_PSHV1 Protein kinase US3 homolog (EC 2.7.11.1)
SCP_PSHV1 Small capsomere-interacting protein
PAP_PSHV1 DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
ORFC_PSHV1 Uncharacterized protein ORFC
OBP_PSHV1 Replication origin-binding protein (OBP) (OriBP)
ORF3_PSHV1 Uncharacterized protein sORF3/4
ORF2_PSHV1 Uncharacterized protein sORF2
ORFA_PSHV1 Uncharacterized protein ORFA
HELI_PSHV1 DNA replication helicase (EC 3.6.4.-)
TEG2_PSHV1 Tegument protein UL11
TRX1_PSHV1 Triplex capsid protein 1
UL32_PSHV1 Packaging protein UL32
NEC2_PSHV1 Nuclear egress protein 2
RIR1_PSHV1 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TEG5_PSHV1 Tegument protein UL47 homolog
SHUT_PSHV1 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
RIR2_PSHV1 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
GM_PSHV1 Envelope glycoprotein M (gM)
DNBI_PSHV1 Major DNA-binding protein
GH_PSHV1 Envelope glycoprotein H (gH)
ATI2_PSHV1 Alpha trans-inducing factor (Tegument protein UL46) (Tegument protein VP11/12)
DPOL_PSHV1 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
CEP1_PSHV1 Cytoplasmic envelopment protein 1
CVC1_PSHV1 Capsid vertex component 1
CVC2_PSHV1 Capsid vertex component 2
AN_PSHV1 Alkaline nuclease (EC 3.1.-.-)
EV45_PSHV1 Envelope protein UL45
KITH_PSHV1 Thymidine kinase (EC 2.7.1.21)
GE_PSHV1 Envelope glycoprotein E (gE)
GD_PSHV1 Envelope glycoprotein D (gD)
CEP2_PSHV1 Cytoplasmic envelopment protein 2
DUT_PSHV1 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GG_PSHV1 Glycoprotein G
HEPA_PSHV1 DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
ICP27_PSHV1 mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27)
MCP_PSHV1 Major capsid protein (MCP)
GC_PSHV1 Envelope glycoprotein C
LTP_PSHV1 Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
GK_PSHV1 Envelope glycoprotein K (Syncytial protein)
GI_PSHV1 Envelope glycoprotein I
ORFB_PSHV1 Uncharacterized protein ORFB
NEC1_PSHV1 Nuclear egress protein 1
GB_PSHV1 Envelope glycoprotein B (gB)
NP04_PSHV1 Nuclear protein UL4
ITP_PSHV1 Inner tegument protein
GL_PSHV1 Envelope glycoprotein L (gL)
ICP4_PSHV1 Major viral transcription factor ICP4 homolog
ORFE_PSHV1 Uncharacterized protein ORFE
GN_PSHV1 Envelope glycoprotein N
US10_PSHV1 Virion protein US10 homolog
TEG3_PSHV1 Tegument protein UL14
UL20_PSHV1 Protein UL20
UNG_PSHV1 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
UL43_PSHV1 Membrane protein UL43
UL01_PSHV1 Uncharacterized protein UL-1
UL13_PSHV1 Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
UL24_PSHV1 Protein UL24
TRM1_PSHV1 Tripartite terminase subunit 1
PORTL_PSHV1 Portal protein
ORFD_PSHV1 Uncharacterized protein ORFD
UL03_PSHV1 Uncharacterized protein UL3
TRX2_PSHV1 Triplex capsid protein 2
US02_PSHV1 Uncharacterized protein US2

69 entries

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

Select_allDeselect_all
KITH_VZVD Thymidine kinase (EC 2.7.1.21)
SCP_VZVD Small capsomere-interacting protein
TRM3_VZVD Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit) [Cleaved into: Gene 42 ...
TEG5_VZVD Tegument protein UL47 homolog
UL13_VZVD Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
UL20_VZVD Protein UL20 homolog (Gene 39 membrane protein)
RIR2_VZVD Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TEG6_VZVD Tegument protein UL55 homolog
TRM2_VZVD Tripartite terminase subunit 2
US03_VZVD Serine/threonine-protein kinase US3 homolog (Protein kinase ORF66) (EC 2.7.11.1)
VP22_VZVD Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
SHUT_VZVD Virion host shutoff protein (Vhs) (EC 3.1.27.-)
HEPA_VZVD DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
ORF1_VZVD Structural protein 1 (Structural ORF1 protein)
IE61_VZVD E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61) (RING-type E3 ...
OBP_VZVD Replication origin-binding protein (OBP) (OriBP)
ORF0_VZVD Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)
MCP_VZVD Major capsid protein (MCP)
NP03_VZVD Nuclear phosphoprotein UL3 homolog (ORF58 protein)
PRIM_VZVD DNA primase (EC 2.7.7.-)
VP16_VZVD Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
TRX1_VZVD Triplex capsid protein 1
TEG3_VZVD Tegument protein UL14 homolog
UL24_VZVD Protein UL24 homolog
NEC2_VZVD Nuclear egress protein 2
PAP_VZVD DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
TEG7_VZVD Tegument protein UL51 homolog (ORF7 protein)
US10_VZVD Virion protein US10 homolog (Genes 64/69 protein)
UL32_VZVD Packaging protein UL32
SCAF_VZVD Capsid scaffolding protein (Protease precursor) (pPR) [Cleaved into: Assemblin (EC 3.4.21.97) ...
RIR1_VZVD Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
CEP3_VZVD Cytoplasmic envelopment protein 3
HELI_VZVD DNA replication helicase (EC 3.6.4.-)
CEP2_VZVD Cytoplasmic envelopment protein 2
CVC2_VZVD Capsid vertex component 2
DUT_VZVD Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
AN_VZVD Alkaline nuclease (EC 3.1.-.-)
DNBI_VZVD Major DNA-binding protein
CEP1_VZVD Cytoplasmic envelopment protein 1
CVC1_VZVD Capsid vertex component 1
GC_VZVD Envelope glycoprotein C (gC) (Glycoprotein V) (gpV)
GL_VZVD Envelope glycoprotein L (gL)
GN_VZVD Envelope glycoprotein N
GB_VZVD Envelope glycoprotein B (gB)
ICP4_VZVD Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
DPOL_VZVD DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GH_VZVD Envelope glycoprotein H (gH)
GM_VZVD Envelope glycoprotein M (gM)
GI_VZVD Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
GE_VZVD Envelope glycoprotein E (gE)
NEC1_VZVD Nuclear egress protein 1
ORF57_VZVD Uncharacterized protein 57 (Uncharacterized ORF57 protein)
ITP_VZVD Inner tegument protein
ICP22_VZVD Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
GK_VZVD Envelope glycoprotein K (Syncytial protein)
MB43_VZVD Membrane protein UL43 homolog (Membrane protein ORF15)
US9_VZVD Envelope protein US9 (Envelope protein 65) (ORF65 protein)
TYSY_VZVD Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
ICP27_VZVD mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4) (Transcriptional transactivator ...
TRX2_VZVD Triplex capsid protein 2
UNG_VZVD Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TEG4_VZVD Tegument protein UL21 homolog
PORTL_VZVD Portal protein
ORF2_VZVD Membrane protein 2 (Membrane ORF2 protein)
ORF32_VZVD Phosphoprotein 32 (ORF32 Phosphoprotein)
LTP_VZVD Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
NP04_VZVD Nuclear protein UL4 homolog (ORF56 protein)
TRM1_VZVD Tripartite terminase subunit 1
TEG1_VZVD Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)

1 entry

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3) reference strain

ORF0_VZVO Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)

2 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus) reference strain

Select_allDeselect_all
IE61_CHV9D E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61)
US9_CHV9D Envelope protein US9 homolog (Envelope protein 65) (ORF65 protein)

1 entry

Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus) reference strain

GE_CHV1 Envelope glycoprotein E (gE)

47 entries

Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
SCP_EHV1V Small capsomere-interacting protein
SCAF_EHV1V Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
TRM1_EHV1V Tripartite terminase subunit 1
VG03_EHV1V Gene 3 protein
TEG5_EHV1V Tegument protein UL47 homolog (GP10)
TEG4_EHV1V Tegument protein UL21 homolog
PRIM_EHV1V DNA primase (EC 2.7.7.-)
UL24_EHV1V Protein UL24 homolog
NP03_EHV1V Nuclear phosphoprotein UL3 homolog (ORF60 protein)
ICP4_EHV1V Major viral transcription factor ICP4 homolog (155 kDa immediate-early protein)
MCP_EHV1V Major capsid protein (MCP)
TEG3_EHV1V Tegument protein UL14 homolog
UL13_EHV1V Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
UNG_EHV1V Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VG75_EHV1V Uncharacterized gene 75 protein
UL20_EHV1V Protein UL20 homolog
TRX1_EHV1V Triplex capsid protein 1
SHUT_EHV1V Virion host shutoff protein (Vhs) (EC 3.1.27.-)
ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Infected cell protein 0) (RING-type E3 ubiquitin ...
CEP3_EHV1V Cytoplasmic envelopment protein 3
GB_EHV1V Envelope glycoprotein B (gB)
CVC2_EHV1V Capsid vertex component 2
AN_EHV1V Alkaline nuclease (EC 3.1.-.-)
CEP1_EHV1V Cytoplasmic envelopment protein 1
DNBI_EHV1V Major DNA-binding protein
HEPA_EHV1V DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
GP2_EHV1V Glycoprotein gp2 (Glycoprotein X) (GpX)
DPOL_EHV1V DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
CEP2_EHV1V Cytoplasmic envelopment protein 2
GL_EHV1V Envelope glycoprotein L (gL)
GN_EHV1V Envelope glycoprotein N
MB43_EHV1V Membrane protein UL43 homolog (Membrane protein ORF17)
ITP_EHV1V Inner tegument protein
NEC2_EHV1V Nuclear egress protein 2
PAP_EHV1V DNA polymerase processivity factor (Polymerase accessory protein) (PAP)
PORTL_EHV1V Portal protein
HELI_EHV1V DNA replication helicase (EC 3.6.4.-)
US9_EHV1V Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
US10_EHV1V Virion protein US10 homolog (Gene 66 protein)
TEG1_EHV1V Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
TRM3_EHV1V Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
GG_EHV1V Envelope glycoprotein G (gG)
VG01_EHV1V Uncharacterized gene 1 protein
OBP_EHV1V Replication origin-binding protein (OBP) (OriBP)
NP04_EHV1V Nuclear protein UL4 homolog
US03_EHV1V Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
VG59_EHV1V Uncharacterized gene 59 protein

45 entries

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Select_allDeselect_all
GE_VZVO Envelope glycoprotein E (gE)
TEG1_VZVO Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
RIR2_VZVO Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
US9_VZVO Envelope protein US9 (Envelope protein 65) (ORF65 protein)
VP22_VZVO Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
PAP_VZVO DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
ORF2_VZVO Membrane protein 2 (Membrane ORF2 protein)
TEG3_VZVO Tegument protein UL14 homolog
TEG6_VZVO Tegument protein UL55 homolog
OBP_VZVO Replication origin-binding protein (OBP) (OriBP)
RIR1_VZVO Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
KITH_VZVO Thymidine kinase (EC 2.7.1.21)
ORF32_VZVO Phosphoprotein 32 (ORF32 Phosphoprotein)
TEG7_VZVO Tegument protein UL51 homolog (Protein ORF7)
PRIM_VZVO DNA primase (EC 2.7.7.-)
DNBI_VZVO Major DNA-binding protein
CEP3_VZVO Cytoplasmic envelopment protein 3
ICP22_VZVO Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
DUT_VZVO Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
ICP4_VZVO Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
AN_VZVO Alkaline nuclease (EC 3.1.-.-)
HELI_VZVO DNA replication helicase (EC 3.6.4.-)
GI_VZVO Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
GK_VZVO Envelope glycoprotein K (Syncytial protein)
HEPA_VZVO DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
DPOL_VZVO DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GH_VZVO Envelope glycoprotein H (gH)
GM_VZVO Envelope glycoprotein M (gM)
MB43_VZVO Membrane protein UL43 homolog (Membrane protein ORF15)
GN_VZVO Envelope glycoprotein N
ICP27_VZVO mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4)
GB_VZVO Envelope glycoprotein B (gB)
LTP_VZVO Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
NP04_VZVO Nuclear protein UL4 homolog (ORF56 protein)
ORF1_VZVO Structural protein 1 (Structural ORF1 protein)
ORF57_VZVO Uncharacterized protein 57 (Uncharacterized ORF57 protein)
NP03_VZVO Nuclear phosphoprotein UL3 homolog (ORF58 protein)
UL13_VZVO Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
UL24_VZVO Protein UL24 homolog
TEG5_VZVO Tegument protein UL47 homolog
TYSY_VZVO Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
VP16_VZVO Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
TEG4_VZVO Tegument protein UL21 homolog
UNG_VZVO Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GL_VZVO Envelope glycoprotein L (gL)

19 entries

Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))

Select_allDeselect_all
PRIM_SUHVK DNA primase (EC 2.7.7.-)
TEG7_SUHVK Tegument protein UL51
PAP_SUHVK DNA polymerase processivity factor (Polymerase accessory protein) (PAP) (UL42 homolog)
UNG_SUHVK Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VNUA_SUHVK Probable nuclear antigen
RIR1_SUHVK Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
SHUT_SUHVK Virion host shutoff protein (Vhs) (EC 3.1.27.-)
RIR2_SUHVK Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SCAF_SUHVK Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
ICP4_SUHVK Major viral transcription factor ICP4 homolog
GK_SUHVK Envelope glycoprotein K (Syncytial protein)
GN_SUHVK Envelope glycoprotein N
DUT_SUHVK Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GM_SUHVK Envelope glycoprotein M (gM)
ICP22_SUHVK Transcriptional regulator ICP22 homolog (Immediate-early protein RSP40)
ICP27_SUHVK mRNA export factor ICP27 homolog (Protein UL54)
KR1_SUHVK Serine/threonine-protein kinase (EC 2.7.11.1)
GH_SUHVK Envelope glycoprotein H (gH)
GL_SUHVK Envelope glycoprotein L (gL)

17 entries

Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus)

Select_allDeselect_all
RIR2_EHV4 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
UL24_EHV4 Protein UL24 homolog
US9_EHV4 Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
RIR1_EHV4 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TEG1_EHV4 Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
VP22_EHV4 Tegument protein VP22 (Gene 11 protein)
TEG7_EHV4 Tegument protein UL51 homolog
GC_EHV4 Envelope glycoprotein C (Glycoprotein 13)
KITH_EHV4 Thymidine kinase (EC 2.7.1.21)
DUT_EHV4 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
EV45_EHV4 Envelope protein UL45 homolog
GB_EHV4 Envelope glycoprotein B (gB)
GG_EHV4 Envelope glycoprotein G (gG)
GH_EHV4 Envelope glycoprotein H (gH)
TEG5_EHV4 Tegument protein UL47 homolog (GP10)
VP16_EHV4 Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
US10_EHV4 Virion protein US10 homolog (ORF3)

15 entries

Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
NP03_HHV1F Nuclear phosphoprotein UL3
TEG1_HHV1F Tegument protein UL46 (Tegument protein VP11/12)
VP16_HHV1F Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
US8A_HHV1F US8.5 protein
LRP2_HHV1F Latency-related protein 2
TRM1_HHV1F Tripartite terminase subunit 1
TEG5_HHV1F Tegument protein UL47 (82/81 kDa tegument protein) (VMW82/81) (VP13/14)
GH_HHV1F Envelope glycoprotein H (gH)
DNBI_HHV1F Major DNA-binding protein
GB_HHV1F Envelope glycoprotein B (gB)
GD_HHV1F Envelope glycoprotein D (gD)
ICP34_HHV1F Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)
US10_HHV1F Virion protein US10
GE_HHV1F Envelope glycoprotein E (gE) (gE-1)
LRP1_HHV1F Latency-related protein 1

14 entries

Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
SCAF_BHV1C Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
RIR1_BHV1C Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
RIR2_BHV1C Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TEG5_BHV1C Tegument protein UL47
UNG_BHV1C Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
VP22_BHV1C Tegument protein VP22
GC_BHV1C Envelope glycoprotein C homolog (Glycoprotein GIII)
GD_BHV1C Envelope glycoprotein D (gD) (Glycoprotein IV)
GM_BHV1C Envelope glycoprotein M (gM)
GH_BHV1C Envelope glycoprotein H (gH)
GB_BHV1C Envelope glycoprotein B (gB)
GN_BHV1C Envelope glycoprotein N
HEPA_BHV1C DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
OBP_BHV1C Replication origin-binding protein (OriBP) (OBP)

14 entries

Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
ICP4_EHV1K Major viral transcription factor (155 kDa immediate-early protein)
US9_EHV1K Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
TEG6_EHV1K Tegument protein UL55 homolog
VG03_EHV1K Gene 3 protein (ORF L1)
VG67_EHV1K Uncharacterized gene 67 protein (IR6 protein)
GP2_EHV1K Glycoprotein gp2 (Glycoprotein X) (GpX)
ICP27_EHV1K mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
GK_EHV1K Envelope glycoprotein K (Syncytial protein)
GD_EHV1K Envelope glycoprotein D (gD) (Glycoprotein 17/18)
KR1_EHV1K Serine/threonine-protein kinase (EC 2.7.11.1)
GG_EHV1K Envelope glycoprotein G (gG)
ICP22_EHV1K Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
US02_EHV1K US1 protein
US10_EHV1K Virion protein US10 homolog (Gene 66 protein) (IR5 protein) (ORF S2-1)

12 entries

Gallid herpesvirus 2 (strain GA) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
US453_GAHVG Uncharacterized 16.6 kDa protein
US384_GAHVG Uncharacterized 14.2 kDa protein
US426_GAHVG Uncharacterized 15.7 kDa protein
US03_GAHVG Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
U1053_GAHVG Uncharacterized 40.6 kDa protein
US420_GAHVG Uncharacterized 15.5 kDa protein
ICP4_GAHVG Major viral transcription factor ICP4 homolog (Immediate-early protein IE175)
GC_GAHVG Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)
GL_GAHVG Envelope glycoprotein L (gL)
US10_GAHVG Virion protein US10 homolog
US441_GAHVG Uncharacterized 16.7 kDa protein
VP38_GAHVG 38 kDa phosphoprotein (Phosphoprotein pp38)

12 entries

Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
RIR2_HHV1K Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SHUT_HHV1K Virion host shutoff protein (Vhs) (EC 3.1.27.-)
GC_HHV1K Envelope glycoprotein C
DPOL_HHV1K DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
EV45_HHV1K Envelope protein UL45 (18 kDa protein)
DNBI_HHV1K Major DNA-binding protein
CEP3_HHV1K Cytoplasmic envelopment protein 3
GD_HHV1K Envelope glycoprotein D (gD)
GK_HHV1K Envelope glycoprotein K (Syncytial protein)
GL_HHV1K Envelope glycoprotein L (gL)
GB_HHV1K Envelope glycoprotein B (gB)
KITH_HHV1K Thymidine kinase (EC 2.7.1.21)

12 entries

Human herpesvirus 2 (strain 333) (HHV-2) (Human herpes simplex virus 2)

Select_allDeselect_all
UNG_HHV23 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
RIR2_HHV23 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
SHUT_HHV23 Virion host shutoff protein (Vhs) (EC 3.1.27.-)
VP16_HHV23 Tegument protein VP16 (Alpha trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65)
RIR1_HHV23 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
GI_HHV23 Envelope glycoprotein I (gI)
EV45_HHV23 Envelope protein UL45 (18 kDa protein)
KITH_HHV23 Thymidine kinase (EC 2.7.1.21)
GD_HHV23 Envelope glycoprotein D (gD)
GB_HHV23 Envelope glycoprotein B (gB)
NP03_HHV23 Nuclear phosphoprotein UL3
GC_HHV23 Envelope glycoprotein C

8 entries

Bovine herpesvirus 1.2 (strain ST) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
YOR1_BHV1S Uncharacterized 16.1 kDa protein (ORF1)
US02_BHV1S Protein US2 homolog
GE_BHV1S Envelope glycoprotein E (gE)
GD_BHV1S Envelope glycoprotein D (gD) (Glycoprotein IV)
GI_BHV1S Envelope glycoprotein I (gI)
US9_BHV1S Envelope protein US9
VGLX_BHV1S Glycoprotein GX
US03_BHV1S Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)

8 entries

Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker) (SuHV-1) (Pseudorabies virus (strain Indiana-Funkhauser / Becker))

Select_allDeselect_all
UNG_SUHVF Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GL_SUHVF Envelope glycoprotein L (gL)
DNBI_SUHVF Major DNA-binding protein
ICP4_SUHVF Major viral transcription factor ICP4 homolog
GB_SUHVF Envelope glycoprotein B (gB)
GC_SUHVF Envelope glycoprotein C homolog (Glycoprotein GIII)
ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Early protein 0) (EP0) (RING-type E3 ubiquitin ...
TRM1_SUHVF Tripartite terminase subunit 1

8 entries

Suid herpesvirus 1 (strain NIA-3) (SuHV-1) (Pseudorabies virus (strain NIA-3))

Select_allDeselect_all
TEG3_SUHVN Tegument protein UL14
TEG4_SUHVN Tegument protein UL21
US03_SUHVN Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
GH_SUHVN Envelope glycoprotein H (gH)
KITH_SUHVN Thymidine kinase (EC 2.7.1.21)
UL20_SUHVN Protein UL20
UL13_SUHVN Serine/threonine-protein kinase UL13 (EC 2.7.11.1)
US02_SUHVN Protein US2 homolog (28 kDa protein)

6 entries

Equine herpesvirus 1 (strain Kentucky D) (EHV-1) (Equine abortion virus)

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GE_EHV1D Envelope glycoprotein E (gE)
GC_EHV1D Envelope glycoprotein C (gC) (Glycoprotein 13)
GD_EHV1D Envelope glycoprotein D (gD) (Glycoprotein 17/18)
GI_EHV1D Envelope glycoprotein I (gI)
EV45_EHV1D Envelope protein UL45 homolog
GB_EHV1D Envelope glycoprotein B (gB)

6 entries

Human herpesvirus 1 (strain HFEM) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
KITH_HHV1E Thymidine kinase (EC 2.7.1.21)
GH_HHV1E Envelope glycoprotein H (gH)
ICP27_HHV1E mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27)
UL56_HHV1E Protein UL56
TEG4_HHV1E Tegument protein UL21
TEG6_HHV1E Tegument protein UL55

6 entries

Suid herpesvirus 1 (strain Rice) (SuHV-1) (Pseudorabies virus (strain Rice))

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US9_SUHVR Envelope protein US9 homolog (11 kDa protein)
GG_SUHVR Envelope glycoprotein G (gG)
GI_SUHVR Envelope glycoprotein I (Glycoprotein GP63)
GD_SUHVR Envelope glycoprotein D (gD) (Protein gp50)
GH_SUHVR Envelope glycoprotein H (gH)
GE_SUHVR Envelope glycoprotein E (gE)

3 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus)

Select_allDeselect_all
US03_CHV9D Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
GE_CHV9D Envelope glycoprotein E (Membrane glycoprotein 2) (gE)
GI_CHV9D Envelope glycoprotein I (Membrane glycoprotein 1)

5 entries

Equine herpesvirus 1 (strain AB1) (EHV-1) (Equine abortion virus)

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GI_EHV1A Envelope glycoprotein I
GD_EHV1A Envelope glycoprotein D (gD) (Glycoprotein 17/18)
GB_EHV1A Envelope glycoprotein B (gB)
GE_EHV1A Envelope glycoprotein E (gE)
UL32_EHV1A Packaging protein UL32 homolog (Glycoprotein 300) (GP300)

5 entries

Equine herpesvirus 1 (strain HVS25A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
GH_EHV1 Envelope glycoprotein H (gH)
GB_EHV1 Envelope glycoprotein B (gB)
KITH_EHV1 Thymidine kinase (EC 2.7.1.21)
UL24_EHV1 Protein UL24 homolog
TRM1_EHV1 Tripartite terminase subunit 1

5 entries

Infectious laryngotracheitis virus (strain Thorne V882) (ILTV) (Gallid herpesvirus 1)

Select_allDeselect_all
UL24_ILTVT Protein UL24 homolog (ORF 3)
SCAF_ILTVT Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
CVC2_ILTVT Capsid vertex component 2
GB_ILTVT Envelope glycoprotein B (gB)
KITH_ILTVT Thymidine kinase (EC 2.7.1.21)

4 entries

Bovine herpesvirus 1.1 (strain P8-2) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
VP16_BHV1P Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
TEG5_BHV1P Tegument protein UL47
GD_BHV1P Envelope glycoprotein D (gD) (Glycoprotein IV)
GB_BHV1P Envelope glycoprotein B (gB)

3 entries

Cercopithecine herpesvirus 1 (CeHV-1) (Simian herpes B virus)

Select_allDeselect_all
US9_CHV1 Envelope protein US9 homolog (10 kDa protein)
GD_CHV1 Envelope glycoprotein D (gD)
VGLJ_CHV1 Envelope glycoprotein J

4 entries

Gallid herpesvirus 2 (strain RB-1b) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
GC_GAHVR Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)
GH_GAHVR Envelope glycoprotein H (gH)
KITH_GAHVR Thymidine kinase (EC 2.7.1.21)
GB_GAHVR Envelope glycoprotein B (gB)

3 entries

Bovine herpesvirus 2 (strain BMV) (BoHV-2) (Bovine mammillitis virus)

Select_allDeselect_all
TRM1_BHV2B Tripartite terminase subunit 1
DNBI_BHV2B Major DNA-binding protein
GB_BHV2B Envelope glycoprotein B (gB)

3 entries

Human herpesvirus 1 (strain Angelotti) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
TRM1_HHV1A Tripartite terminase subunit 1
DPOL_HHV1A DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GD_HHV1A Envelope glycoprotein D (gD)

3 entries

Human herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1)

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RNB_HHV1M RNA-binding protein (Vmw21)
EV45_HHV1M Envelope protein UL45 (18 kDa protein)
GK_HHV1M Envelope glycoprotein K (Syncytial protein)

3 entries

Human herpesvirus 2 (strain G) (HHV-2) (Human herpes simplex virus 2)

Select_allDeselect_all
TRX1_HHV2G Triplex capsid protein 1
SHUT_HHV2G Virion host shutoff protein (Vhs) (EC 3.1.27.-)
GC_HHV2G Envelope glycoprotein C (Glycoprotein F)

2 entries

Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)

Select_allDeselect_all
KITH_FHV1 Thymidine kinase (EC 2.7.1.21)
GH_FHV1 Envelope glycoprotein H (gH)

2 entries

Gallid herpesvirus 2 (strain bc-1) (GaHV-2) (Marek's disease herpesvirus type 1)

Select_allDeselect_all
EV45_GAHVB Envelope protein UL45 homolog
GC_GAHVB Envelope glycoprotein C homolog (A antigen) (Glycoprotein A) (GA) (Secretory glycoprotein GP57-65)

2 entries

Herpes simplex virus type 2 (strain SA8) (Simian agent 8)

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GB_HSV2S Envelope glycoprotein B (gB)
ICP47_HSV2S ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...

2 entries

Human herpesvirus 1 (strain Patton) (HHV-1) (Human herpes simplex virus 1)

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GD_HHV1P Envelope glycoprotein D (gD)
GB_HHV1P Envelope glycoprotein B (gB)

2 entries

Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus 1)

Select_allDeselect_all
DPOL_HHV1S DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
KITH_HHV1S Thymidine kinase (EC 2.7.1.21)

2 entries

Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2)

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AN_HHV2 Alkaline nuclease (EC 3.1.-.-)
DNBI_HHV2 Major DNA-binding protein

2 entries

Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
KITH_MEHV1 Thymidine kinase (EC 2.7.1.21)
GH_MEHV1 Envelope glycoprotein H (gH)

2 entries

Meleagrid herpesvirus 1 (strain FC126) (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
KITH_MEHVF Thymidine kinase (EC 2.7.1.21)
GC_MEHVF Envelope glycoprotein C homolog (A antigen) (Glycoprotein A)

2 entries

Meleagrid herpesvirus 1 (strain H2) (MeHV-1) (Turkey herpesvirus)

Select_allDeselect_all
GC_MEHVH Envelope glycoprotein C homolog (A antigen) (Glycoprotein A)
EV45_MEHVH Envelope protein UL45 homolog (23.5 kDa protein)

2 entries

Saimiriine herpesvirus 1 (strain MV-5-4-PSL) (SaHV-1) (Marmoset herpesvirus)

Select_allDeselect_all
GB_SHV1 Envelope glycoprotein B (gB)
KITH_SHV1 Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 1 (strain 6660) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV16 Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 1.1 (strain Jura) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1J E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain K22) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain Q3932) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV1Q Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 2 (strain BHM-1) (BoHV-2) (Bovine mammillitis virus)

KITH_BHV2H Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 5 (strain N569) (BoHV-5) (Bovine encephalitis herpesvirus)

KITH_BHV5 Thymidine kinase (EC 2.7.1.21)

1 entry

Cercopithecine herpesvirus 1 (strain E2490) (CeHV-1) (Simian herpes B virus)

ICP47_CHV1E ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...

1 entry

Cercopithecine herpesvirus 16 (CeHV-16) (Herpesvirus papio 2)

ICP47_CHV16 ICP47 protein (Immediate-early protein IE12) (Immediate-early-5) (Infected cell protein 47) (US12 ...

1 entry

Equine herpesvirus 1 (strain HH1) (EHV-1) (Equine abortion virus)

VG01_EHV1H Uncharacterized gene 1 protein

1 entry

Gallid herpesvirus 2 (strain MD11/75C/R2) (GaHV-2) (Marek's disease herpesvirus type 1)

VP38_GAHVN 38 kDa phosphoprotein (Phosphoprotein pp38)

1 entry

Herpesvirus ateles type 1 (strain Lennette)

GB_HSVA1 Envelope glycoprotein B (gB)

1 entry

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)

KITH_HHV1 Thymidine kinase (EC 2.7.1.21)

1 entry

Human herpesvirus 1 (strain A44) (HHV-1) (Human herpes simplex virus 1)

TRX1_HHV14 Triplex capsid protein 1

1 entry

Human herpesvirus 1 (strain CL101) (HHV-1) (Human herpes simplex virus 1)

KITH_HHV1C Thymidine kinase (EC 2.7.1.21)

1 entry

Human herpesvirus 1 (strain CVG-2) (HHV-1) (Human herpes simplex virus 1)

ICP34_HHV1D Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)

1 entry

Human herpesvirus 1 (strain HZT) (HHV-1) (Human herpes simplex virus 1)

GD_HHV1H Envelope glycoprotein D (gD)

1 entry

Human herpesvirus 1 (strain MGH-10) (HHV-1) (Human herpes simplex virus 1)

ICP34_HHV1N Neurovirulence factor ICP34.5 (Infected cell protein 34.5) (protein gamma(1)34.5)

1 entry

Human herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1)

GK_HHV1R Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain R19) (HHV-1) (Human herpes simplex virus 1)

GK_HHV19 Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 2 (strain 186) (HHV-2) (Human herpes simplex virus 2)

DPOL_HHV21 DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)

1 entry

Human herpesvirus 2 (strain B4327UR) (HHV-2) (Human herpes simplex virus 2)

GG_HHV2B Envelope glycoprotein G (gG) (gG-2)

1 entry

Infectious laryngotracheitis virus (strain 632) (ILTV) (Gallid herpesvirus 1)

GB_ILTV6 Envelope glycoprotein B (gB)

1 entry

Infectious laryngotracheitis virus (strain SA-2) (ILTV) (Gallid herpesvirus 1)

GB_ILTVS Envelope glycoprotein B (gB)

1 entry

Suid herpesvirus 1 (strain Indiana S) (SuHV-1) (Pseudorabies virus (strain Indiana S))

MCP_SUHVS Major capsid protein (MCP)