Aparavirus (taxid:1213379)



Non enveloped, pseudo T=3 icosahedral capsid, about 30 nm in diameter.



Monopartite, linear ssRNA(+) genome of 8.0-10.2 kb kb, with a VPg bound at the 5'-terminus and a 3'-polyA tract. Contains two non-overlapping open reading frames, ORF1 and ORF2, which respectively encode the nonstructural and structural proteins.


The virion RNA is infectious and serves as both genome and mRNA. The genome ORF1 and ORF2 encode two polyproteins, the first of which encodes the non-structural proteins helicase, 3C-protease and RNA-dependent RNA polymerase, while the second encodes four capsid proteins. Each ORF is preceded by an internal ribosome entry site (IRES) located at the 5' end and at the intergenic region (IGR) between the two ORFs. Tha IGR IRES allows translation of ORF2 at a non-AUG codon.



  1. Virus penetrates into the cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Synthesis and proteolytic cleavage of the replicase polyprotein RNA1.
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the RNA2 polyprotein (structural proteins).
  7. virus release.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

3 entries grouped by strain

3 entries

Acute bee paralysis virus (strain Rothamsted) (ABPV) reference strain

POLS_ABPVR Structural polyprotein [Cleaved into: Protein VP1 (Virion protein 2); Protein VP4 (Virion protein ...
POLN_ABPVR Replicase polyprotein (EC (EC 3.4.22.-)
POG_ABPVR Putative protein pog (ORFx protein)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Acute bee paralysis virus (strain Rothamsted) taxid:1217067

Protein ModelArchive
Structural polyprotein ma-jd-viral-08840

Mud crab virus taxid:932662

Protein ModelArchive
Structural polyprotein ma-jd-viral-08861

Solenopsis invicta virus 1 taxid:294369

Protein ModelArchive
Nonstructural polyprotein ma-jd-viral-00291
Structural polyprotein ma-jd-viral-08833

Taura syndrome virus taxid:142102

Protein ModelArchive
Capsid protein ma-jd-viral-08843