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Update on SARS-CoV-2 / COVID-19 July 2021
The variant page describes all variants designated as "Variant of Concern" (VOC) or "Variant of Interest" (VOI) from WHO.
Variant sequences can be parsed from UniProt P0DTC2 at COVID-19 pre-release portal.

Update on SARS-CoV-2 / COVID-19 May 2021
Updates of the SARS-CoV-2 life-cycle, its interactome and variants page

Update on SARS-CoV-2 / COVID-19 March 2021
One page describes the SARS circulating variants with list of variations. The SARS-CoV-2 replication cycle has been updated to add fusion directly at the cell surface, and host inhibitions by the virus.

Update on SARS-CoV-2 / COVID-19 December 2020
Minor updates, and ORF3b, 3c and ORF3d entries have been added to minimize confusion around those alternatives ORFs

Update on SARS-CoV-2 / COVID-19 June 2020
Interactome,links and protein annotation has been updated.

Update on SARS-CoV-2 / COVID-19 April 2020
A SARS-Cov-2 / Covid-19 dedicated resource has been released

Virosaurus update April 2020 image
Virosaurus (from virus thesaurus) is a curated virus genome database, aimed at facilitating clinical metagenomics analysis. The database has been updated, adding last SARS-Cov-2 sequences. It provides also non vertebrates viruses (insects, fungus, eukaryotic microorgansims) and plant virus sections.

Update on SARS-CoV-2 / COVID-19 March 2020
The nCoV virus has received an official name: SARS coronavirus 2 (SARS-CoV-2). WHO has named the disesae COVID-19. Coronavirus pages have been updated. Spike protein analysis has allowed predicting integrin binding: A potential role for integrins in host cell entry by SARS-CoV-2 Antiviral Res. 2020 Mar 1:104759

Novel Coronavirus (SARS-Cov-2) February 2020 image
The annotated proteome is accessible at SARS-CoV-2 proteome. UniProt provides pre-release access to these sequences from the current public health emergency. The data will become part of a future UniProt release and may be subject to further changes.

Wuhan Coronavirus January 2020 image
Wuhan 2020 Coronavirus (nCoV) belongs to the Betacoronavirus. These viruses are spread in many vertebrate species and cause respiratory diseases. SARS and Wuhan 2020 nCoV are Zoonosis causing pneumonia with risk of fatal cases. Human Coronavirus OC43 (or Betacoronavirus 1) is widespread and may cause 10-15% of common colds.

Virosaurus November 2019 image
Virosaurus (from virus thesaurus) is a curated virus genome database, aimed at facilitating clinical metagenomics analysis. The data comprises clustered and annotated sequences of Vertebrate viruses in FASTA format. Virosaurus also provides complete genome database for all those viruses.

Antiviral drugs May 2019 image
Most common antiviral drugs have been added to ViralZone pages: EboV, HBV, HCV, HHV-1, HHV-5, ... HIV resource has been expanded with HIV antiretroviral drugs

>>News archive

VIROLOGY NEWS image TWIV:This Week in Virology is a weekly podcast animated by professors Vincent Racaniello and Dick Despommier from the Columbia University, USA.

Virology and Bioinformatics from
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure Curated by Dr. Chris Upton

Publication: ViralZone: a knowledge resource to understand virus diversity. Hulo C, de Castro E, Masson P, Bougueleret L, Bairoch A, Xenarios I, Le Mercier P. Nucleic Acids Res. 2011 Jan;39(Database issue):D576-82.

ViralZone current statistics
July, 2021
702 Virus description pages:
  • 128 Families
  • 567 Genera
  • 7 individual Species

216 Viral molecular biology pages

Linking to:
(UniProt release 2021_02)

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This work is licensed under a Creative Commons Attribution 4.0 International License.
Please cite the source ViralZone,
SIB Swiss Institute of Bioinformatics

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