Deltacoronavirus (taxid:1159901)



Enveloped, spherical, about 120 nm in diameter. The RNA genome is associated with the N protein to form the nucleocapsid.



Monopartite, linear ssRNA(+) genome of 26-26.5 kb in size. Capped, and polyadenylated. The leader RNA at the 5' end of the genome is also present at the end of each subgenomic RNAs.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. Genomic RNA encodes for ORF1a, as for ORF1b, it is translated by ribosomal frameshifting. Resulting proteins pp1a and pp1ab are processed into the viral polymerase (RdRp) and other non-structural proteins involved in RNA synthesis. Structural proteins are expressed as subgenomic RNAs. Each RNA (genomic and subgenomic) is translated to yield only the protein encoded by the 5'-most ORF.




  1. Attachment of the viral S protein to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion of virus membrane with the endosomal membrane (probably mediated by S2), ssRNA(+) genome is released into the cytoplasm.
  3. Synthesis and proteolytic cleavage of the replicase polyprotein.
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Synthesis of structural proteins encoded by subgenomic mRNAs.
  7. Assembly and budding at membranes of the endoplasmic reticulum (ER), the intermediate compartments, and/or the Golgi complex.
  8. Release of new virions by exocytosis.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Common moorhen coronavirus HKU21 taxid:1159902

Protein ModelArchive
Envelope protein ma-jd-viral-48311
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03166
NS6 protein ma-jd-viral-07597
NS7a protein ma-jd-viral-32602
NS7b protein ma-jd-viral-47633
NS7c protein ma-jd-viral-00690
Nucleocapsid protein ma-jd-viral-57211

Magpie-robin coronavirus HKU18 taxid:1159903

Protein ModelArchive
Envelope protein ma-jd-viral-48304
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03190
NS6 protein ma-jd-viral-07593
NS7a protein ma-jd-viral-35794
NS7b protein ma-jd-viral-00688
NS7c protein ma-jd-viral-55183
Nucleocapsid protein ma-jd-viral-57222

Munia coronavirus HKU13-3514 taxid:572289

Protein ModelArchive
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03165
Nonstructural protein ma-jd-viral-00687
Nonstructural protein ma-jd-viral-07590
Nonstructural protein ma-jd-viral-55182
Nonstructural protein ma-jd-viral-57468
Nucleocapsid phosphoprotein ma-jd-viral-57233
Small membrane protein ma-jd-viral-48308

Night heron coronavirus HKU19 taxid:1159904

Protein ModelArchive
Envelope protein ma-jd-viral-48310
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03180
NS6 protein ma-jd-viral-07599
NS7a protein ma-jd-viral-00691
NS7b protein ma-jd-viral-51997
Nucleocapsid protein ma-jd-viral-57221

Sparrow coronavirus HKU17 taxid:1159906

Protein ModelArchive
Envelope protein ma-jd-viral-48312
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03170
NS6 protein ma-jd-viral-07595
NS7a protein ma-jd-viral-00685
NS7b protein ma-jd-viral-57034
Nucleocapsid protein ma-jd-viral-57218

Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007) taxid:572290

Protein ModelArchive
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03152
Nonstructural protein ma-jd-viral-00686
Nonstructural protein ma-jd-viral-07598
Nonstructural protein ma-jd-viral-55181
Nonstructural protein ma-jd-viral-57466
Nucleocapsid phosphoprotein ma-jd-viral-57237
Small membrane protein ma-jd-viral-48305

White-eye coronavirus HKU16 taxid:1159907

Protein ModelArchive
Envelope protein ma-jd-viral-48306
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03194
NS6 protein ma-jd-viral-07596
NS7a protein ma-jd-viral-55709
NS7b protein ma-jd-viral-32277
Nucleocapsid protein ma-jd-viral-57216

Wigeon coronavirus HKU20 taxid:1159908

Protein ModelArchive
Envelope protein ma-jd-viral-48307
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane... ma-jd-viral-03156
NS6 protein ma-jd-viral-07591
NS7a protein ma-jd-viral-50260
NS7b protein ma-jd-viral-62892
NS7c protein ma-jd-viral-39937
NS7d protein ma-jd-viral-52861
Nucleocapsid protein ma-jd-viral-57241