Aureusvirus (taxid:186457)



Non-enveloped, spherical, icosahedral, about 30 nm in diameter, capsid with a T=3 icosahedral symmetry. 30 hexameric capsomers per nucleocapsid (virion composed of 180 protein subunits).



Linear, ssRNA(+) genome of 4.4 kb, which lacks a cap structure and a poly(A)tail.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. Two 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1. The downstream genes encoding the movement protein and capsid proteins are translated from two subgenomic RNAs. The viral suppressor of RNA silencing (VSRs) protein is expressed by leaky scanning from the MVP mRNA.
Cap-independent translation is mediated possibly through the interaction between a 3'-cap-independent translation element and a 5'UTR stem-loop.




  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes internal subgenomic promoters on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNAs that will generate the capsid and movement protein.
  7. Virus assembly in the cytoplasm.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Aureusviruses encode P14 which acts as a suppressor of RNA silencing .

Matching UniProtKB/Swiss-Prot entries

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4 entries grouped by strain

4 entries

Pothos latent virus (isolate Pigeonpea/India) (PoLV) reference strain

RDRP_POLVP RNA-directed RNA polymerase (EC (Protein p84) [Cleaved into: Protein p25]
MVP_POLVP Movement protein (p27)
CAPSD_POLVP Capsid protein (p40)
P14_POLVP RNA silencing suppressor p14