Furovirus (taxid:12291)

VIRION

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Non-enveloped, rod shaped with helical symmetry. The virion is composed of two segments about 140-160 nm and 260-300nm in length and 20 nm in diameter.

GENOME

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Segmented, linear, ssRNA(+) genome. The two segments are 6-7 kb and 3.5-3.6 kb in size respectively. The genomic RNAs are capped, and display a tRNA-like structure in 3'.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The virion RNA is infectious and serves as both the genome and viral messenger RNA. The RNA-1 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1. The downstream gene encoding the movement protein (MP) is probably translated from a subgenomic RNA. Suppression of termination on RNA-2 produces the extended capsid protein. The 19k protein is a viral suppressor of RNA silencing.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the movement protein, viral suppressor of RNA silencing (VSR) and capsid protein.
  7. Virus assembly in the cytoplasm. Each segment (if multipartite) is encapsidated.
  8. Viral movement protein probably mediate virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Soilborne wheat mosaic virus (SBWMV) 19K protein suppresses RNA silencing . .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

5 entries grouped by strain

5 entries

Soil-borne wheat mosaic virus (strain United States/Nebraska/1981) (SBWMV) reference strain

Select_allDeselect_all
RDRP_SBWMN Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (209 kDa readthrough ...
CAPSD_SBWMN Capsid protein (Coat protein) (P19)
MVP_SBWMN Movement protein (37 kDa protein) (Cell-to-cell transport protein)
VSR_SBWMN Suppressor of RNA silencing (19kD cysteine rich protein) (P19)
CPRT_SBWMN 84 kDa readthrough protein (CP-RT)