Human viruses and associated pathologies
The table below provides a list of human viral pathogens with transmission information and general facts about associated pathologies.

(See human viruses by Baltimore classification)
Virus Genus, Family Host:
Reservoir [occasional]		 Epidemiology Incidence/year
prevalence		 Geography Transmission Tropism:
Organ [cell]
Pathology: Common [Rare, (complication risk CR)]Fatality rate
 Vaccine Antivirals Genome assembly Genome (non-segmented) Proteome Cell culture
BK polyomavirus (BKPyV) Polyomavirus, Polyomaviridae Human Endemic Prevalence: 82%-90% Worldwide Urine or blood Kidney image [Proximal tubule epithelial cell image, Collecting duct cell image, Glomerular cell image]
Persistence: (Latency) Kidney? image
Asymptomatic/Mild0%
[(Immunodeficiency): Nephropathy]
[(Immunodeficiency): hemorrhagic cystitis]
[(Immunodeficiency): Pneumonia]
 Not available GCF_000837865 NC_001538 Proteome
Banna virus (BAV) Seadornavirus, Reoviridae Cattle, Pig, Culex mosquito, [Human] Sporadic Incidence <1/year

Asia (Vietnam, Indonesia, and China)

Country
Indonesia
China
 Zoonosis, Arbovirus, arthropod bite Unknown, [Nervous system image]
Mild0%
[Encephalitis]Unknown
 Not available GCF_000858185 NA Proteome
Barmah forest virus (BFV) Alphavirus, Togaviridae Marsupials, Aedes mosquito , [Human] Sporadic Incidence: 1000-2000/year Australia Zoonosis, Arbovirus, arthropod bite Unknown , Joint tissue image
Mild (Fever)0%
Polyarthritis0%
 Not available GCF_000847585 NC_001786 Proteome
Bunyamwera virus (BUNV)
+Cache Valley virus (CVV)		 Orthobunyavirus, Bunyaviridae, Bunyamwera serogroup Primates, Aedes mosquito, [Human] Sporadic Unknown (low, underreported) (BUNV: Africa (Central Africa, Madagascar) ),
(CVV: North America)		 Zoonosis, Arbovirus, arthropod bite Unknown
Mild (Fever, headache, arthralgia, Rash)0%
Polyarthritis0%
[Encephalitis]Unknown
 GCF_000849925 NA Proteome Not available
Batai virus (BATV) +Chittoor virus (CHITV) Orthobunyavirus, Bunyaviridae, Bunyamwera serogroup Vertebrate, Aedes mosquito, Anopheles Mosquito, Culex mosquito, [Human, Bovine] Sporadic Unknown (very low) Asia, Europe, Africa, Australia Zoonosis, Arbovirus, arthropod bite Unknown
Mild (Fever, headache)unknown
 Not available GCF_004789555 NA Proteome
Ngari virus (NRIV) Orthobunyavirus, Bunyaviridae, Bunyamwera serogroup Vertebrate, Aedes mosquito, [Human] Sporadic Unknown (very low) Central Africa, Madagascar Zoonosis, Arbovirus, arthropod bite Unknown
Mild (Fever, headache)0%
[Hemorrhagic fever]Unknown
 GCA_009732395 NA Proteome Not available
La Crosse encephalitis virus (LACV), (Bunyavirus La Crosse) Orthobunyavirus, Bunyaviridae, California serogroup Mammals, Culex mosquito , [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Nasal turbinates image, Nervous system image [Neuron image]
Mild (Nausea, Headache, Vomiting and Fever)0%
[Encephalitis, La Crosse Encephalitis]
<1%
 GCF_000850965 NA Proteome
Snowshoe hare virus (SSHV), (Bunyavirus snowshoe hare) Orthobunyavirus, Bunyaviridae, California serogroup Rodent, Aedes mosquito, Culiseta mosquito, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Nasal turbinates? image, Nervous system image [Neuron image]
Mild0%
[Encephalitis]0%
 GCF_004789895 NA Proteome
Macacine alphaherpesvirus 1; (McHV-1) , image (=Cercopithecine herpesvirus 1 (CHV-1); Macacine herpesvirus 1 , Herpesvirus simiae, or Herpes virus B) Simplexvirus, Herpesviridae Macaque, [Human] Sporadic <1/year Asia, Indonesia Zoonosis, animal bite Primary: Mucous epithelium
Secondary: Nervous system image [Neuron image] Heart image, Liver image, Spleen image, Lung image, Kidney image, and Adrenal glands
Acute transverse myelitis (ascending myelitis)0%
[40%: Encephalitis]80%
 GCF_000846965 NC_006560 Proteome
Chandipura virus (CHPV) Vesiculovirus, Rhabdoviridae Sandflies, [Human] Sporadic, Outbreaks (2009) 52 [15]
(2010) 50 [16]		 Asia (India, Bhutan, Nepal, Sri Lanka), Africa (Nigeria, Senegal) Zoonosis, Arbovirus, arthropod bite Nervous system image
Mild (Fever, Headache, Myalgia)0%
[(Children):Encephalitis]56-75%
 GCF_000906815 NC_020805 Proteome
Chikungunya virus (CHIKV) WHO ECDC Alphavirus, Togaviridae Vertebrate, Aedes mosquito, [Human] Outbreaks (2023) 460,000 [360] Africa, Asia Zoonosis, Arbovirus, arthropod bite Skin image [Skin fibroblasts image, Keratinocytes image, Melanocytes], Skeletal muscle [Myoblast, Myosatellite cell], Joint tissue [Synovial fibroblasts, satellite cell, Chondrocytes] and Bone marrow image [Osteoclasts]
Mild0%
Chikungunya (Fever, Myalgia, Arthralgia, Headache, back pain, Nausea, and fatigue)<0.1%
(60+ years) 0.6%
[Polyarthritis]0%
[Post-viral fatigue syndrome (PVFS)]
 GCF_000854045 NC_004162 Proteome
Human Cosavirus A (HCoSV-A) Cosavirus, Picornaviridae Human Unknown Fecal-oral (probable) Unknown
Gastroenteritis?0%
 GCF_000885595 NC_012800 Proteome
Cowpox virus (CPXV) Orthopoxvirus, Poxviridae Rodents, [Human, cats, cattle] Sporadic, Outbreaks Incidence: <5/year Europe (Norway, Northern Russia, Northern Italy, France, and Great Britain), Asia (Turkmenia) Zoonosis, contact Skin image, Immune system image [Macrophage image]
Mild; Skin ulcers, Lymphadenopathy0%
[Conjunctivitis]0%
 GCF_000839185 NC_003663 Proteome
Coxsackievirus A (CVA), Enterovirus 71 (EV-71) (=Enterovirus A) ECDC image Enterovirus, Picornaviridae Human Endemic, (Children) Outbreaks Prevalence: 55% (CVA-16) Worldwide; (Enterovirus 71): more common in Asia-pacific Fecal-oral; Vertical transmission Primary: Tonsil image, Mouth mucosa image, Gastrointestinal tract? image
-First viremia
Secondary: Skin image, Respiratory tract image [Respiratory epithelial cell], Heart image, Nervous system image image
Mild0%
[(Children) (EV-71, CVA16):Hand, foot and mouth disease]0.78%
[(Children):Conjunctivitis (CVA24)]0%
[(Children):Herpangina]
[(Children):Acute flaccid myelitis]
[(Children):Aseptic meningitis]
 (China) EV-71 vaccine [Inactivated] GCA_008766895 U22521 Proteome
Coxsackievirus B (CVB) (=Enterovirus B) ECDC Enterovirus, Picornaviridae Human Seasonal (Summer), Endemic Prevalence: 6-50% Worldwide Fecal-oral; Vertical transmission Primary: Gastrointestinal tract image, "Oropharyngeal mucosa?, Spleen image, Mesenteric Lymph node
-First viremia
Secondary: Pancreas image, Heart image [Cardiac muscle cell], Nervous system image
Persistence: (Latency) Gastrointestinal tract image, Pancreas image, blood cells and Thymus image
Mild
[(Persistence): Type 1 diabetes mellitus?]unknown
[(Newborns): Myocarditis]6%
[(Newborns): Pericarditis]
[(Newborns): Pancreatitis]
[(Newborns): paralysis]
[(Newborns): sudden death]
[Post-viral fatigue syndrome (PVFS)]
 Not available GCF_000861905 NC_001612 Proteome
Crimean-Congo hemorrhagic fever virus (CCHFV) image Orthonairovirus, Bunyaviridae,
Crimean-Congo hemorrhagic fever virus (CCHFV) serogroup		 Tick, [Human, Vertebrates] Sporadic Incidence: 10-500/year Africa, Europe (Balkans, Greece), Asia (Middle East and west Asia) Zoonosis, Arbovirus, arthropod bite Primary: Immune system image [Dendritic cells image, Macrophage image]
-Viremia
Secondary: Endothelial cell image, Liver image
Hemorrhagic fever10-40%
 GCF_000854165 NA Proteome
Dengue virus (DENV)
image ECDC		 Flavivirus, Flaviviridae Human, Aedes Aegypti mosquito, Aedes Albopictus mosquito Outbreaks (2023) 6 million [6000] North America and South America, Central Africa, Australia, Oceania, Asia, Europe (Italy, France, Spain) Zoonosis, Arbovirus, arthropod bite Primary: Skin image [Keratinocytes image], Immune system image [Dendritic cells], image], lymph node image [Macrophage image],
Viremia
Secondary: Immune system image [Myeloid dendritic cell image] Liver image [Hepatocyte image, Kupffer cell image]
95-99% Mild ( fever, headache, vomiting, muscle and joint pains)0%
[0.5-5% Dengue hemorrhagic fever (DHF)](Treated)<1%
(untreated)10-20%
[(Children) 0-3% Dengue shock syndrome (DSS)](Treated)1-10%
(Untreated)20-50%
[Post-viral fatigue syndrome (PVFS)]
 Dengue vaccine
[TAK-003 (Qdenga) (Dengue 1, 2, 3 and 4): Attenuated, injection (2)]
[People with previous Dengue infection: CYD-TDV (Dengvaxia) (Dengue 1, 2, 3 and 4): Attenuated, injection (3)]		 GCF_000862125 NC_001477 Proteome
Dhori virus (DHOV)
+Batken virus (BKNV)
+Bourbon virus (BRBV)
+Thogotovirus (THOV)
Thogotovirus, Orthomyxoviridae Tick, Vertebrate [Human, Mosquitoes] Sporadic Low incidence,
(1960 to 2015) 8 [2], underreported 		(DHOV, THOV) Africa, Asia, Europe, (BKNV) Europe, (BRBV) North America Zoonosis, Arbovirus, arthropod bite Liver image, Lung image, Spleen image, Kidney image
Mild (Fever)0%
Thrombocytopaenia, LeukopeniaUnknown
[(THOV) Aseptic meningitis]Unknown
[40% (DHOV) Encephalitis]Unknown
 GCF_002116195 Unknown Proteome
Dugbe virus (DUGV) Orthonairovirus, Nairoviridae
Nairobi sheep disease orthonairovirus (NSDV) serogroup		 Vertebrate, Tick, [Human, Rodent, Ruminants, Monkeys, and Birds] Sporadic Incidence: very low <1 year, underreported Africa Zoonosis, Arbovirus, arthropod bite Unknown
Mild0%
Thrombocytopaenia Unknown
 Not available GCF_000850985 NA Proteome
Beiji nairovirus (BJNV) Norwavirus, Nairoviridae Vertebrate, Tick, [Human, sheep, cattle] Sporadic, Seasonal (spring-summer) Incidence: very low <40 year, underreported Asia (China, Mongolia) Zoonosis, Arbovirus, arthropod bite Unknown (Liver, heart and kidney?)
Mild (fever, headache)0%
Respiratory failure1-2%
 Not available (ribavirin) GCF_029888155 NA Proteome
Eastern equine encephalitis virus (EEEV)
image		 Alphavirus, Togaviridae Birds, Aedes mosquito, Culex mosquito, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Primary: Unknown (no lymphoid tissues)
Secondary: Bone marrow image [Osteoblasts image], Nervous system image
Febrile ilness0%
[Encephalitis]30%
 GCF_000862705 NC_003899 Proteome
Ebolavirus Za?re (EBOV, ZEBOV)
+ ebolavirus Bombali (BOMV)
+ ebolavirus Bundibugyo (BDBV, BEBOV)
+ ebolavirus Reston (RESTV, REBOV)
+ ebolavirus For?t de Ta? (TAFV, CIEBOV)
+ ebolavirus Soudan (SUDV, SEBOV) 		Ebolavirus, Filoviridae Bat, [Monkeys, Human] Outbreaks Africa ( Central Africa (EBOV), West Africa (EBOV,BOMV), Sudan (SUDV) , C?te d'Ivoire (TAFV), Uganda (BDBV, SUDV) ), Asia( Philippines (RESTV)) Zoonosis, contact Primary: Immune system image [Dendritic cells image, Macrophage image]
-Viremia
Secondary: Liver image [hepatocyte image], Lung image [Alveolar macrophage image, Alveolar fibroblast cell image, Lung endothelial cell image], Kidney image [Kidney cell], Spleen image [Splenocytes image, Splenic fibroblast image], Skin image [Skin fibroblasts image], Gastrointestinal tract image; Intestinal epithelium image [Intestinal epithelial cell image]
Hemorrhagic fever(EBOV) 50%, (RESTV) 0%
[Post-viral fatigue syndrome (PVFS)]
 Ebolavirus Zaire (EBOV) vaccines [VSV vector, Injection (IM) (1+)], [Adenovirus vector, Injection (IM) (2)] (EBOV) Monoclonal antibodies, Remdesivir GCF_000848505 NC_002549 Proteome
Echovirus (EV) ECDC Enterovirus, Picornaviridae Human Endemic Worldwide Fecal-oral Larynx epithelium image [Multi-ciliated epithelial cell image] or Intestinal epithelium image [Intestinal epithelial cell image], Mucosal M cells image;
Secondary: Nervous system image, Liver image , Spleen image, Bone marrow image, Heart image, and Lung image
Upper respiratory infection (URI)(Newborn up to 6%)
Aseptic meningitis
Encephalitis
Myocarditis
 Not available GCF_000861505 NC_001897 Proteome
Encephalomyocarditis virus (EMCV) Cardiovirus, Picornaviridae Rodent, [Human, Pig] Sporadic Zoonosis Nervous system image [Neuron image], Heart image [Cardiomyocyte image], Pancreas image [pancreatic cell]
EncephalitisUnknown
 GCF_000862985 NC_001479 Proteome
Epstein-Barr virus (EBV) image Lymphocryptovirus, Herpesviridae Human Endemic Contact, saliva Primary: Buccal epithelium image [Oral mucosa squamous cell image]
-Viremia
Secondary: Immune system image [B-lymphocyte image, T-lymphocyte image, Mature NK cell image]
Persistence: (Latency) Immune system image [B-lymphocyte image]
Mononucleosis<0.1%
[Acute transverse myelitis (ascending myelitis)]
[Post-viral fatigue syndrome (PVFS)]
- Oncovirus-
[Burkitt lymphoma]13-40%
[Nasopharyngeal carcinoma]6-14%
[Hodgkin lymphoma]
[(Persistence) Multiple sclerosis?
 Not available GCF_002402265 NC_007605 Proteome
Hepatitis G virus (HGV) Pegivirus, Flaviviridae Human Endemic Blood, occasionally sexual Liver image [hepatocyte image]
None known0%
 Not available GCF_000862005 NC_001710 Proteome
Hendra virus (HeV) Henipavirus, paramyxoviridae Bat, [Human, Horse] Sporadic Zoonosis, Animal bite Endothelial cell image and Nervous system image [Neuron image]
Encephalitis50%
 GCF_000852685 NC_001906 Proteome
Hepatitis A virus (HAV) Hepatovirus, picornaviridae Human Endemic Fecal-oral Liver image [hepatocyte image], Intestinal epithelium image [Intestinal epithelial cell image], Salivary glands image, Immune system? image [T-lymphocytes? image]
Hepatitis0.015%
[Cryoglobulinemia]
 Hepatitis A vacine [Attenuated or Inactivated, Injection (2)] GCF_000860505 NC_001489 Proteome
Hepatitis B virus (HBV) Orthohepadnavirus, Hepadnaviridae Human, Non-human primates Endemic Sexual contact, Contact: blood, Vertical transmission Transported: in blood by [Macrophage image]
Primary: Liver image [hepatocyte image]
Persistence: (Chronic) Liver image [hepatocyte image]
Hepatitis
[Chronic liver disease]
[Cirrhosis]0.2%
- Oncovirus-
[Hepatocellular carcinoma]4%
 Hepatitis B vaccine [Subunit, Injection (IM) (3)] (Entecavir, Tenofovir, Adefovir, Lamivudine, Telbivudine) GCF_000861825 NC_003977 Proteome
Hepatitis C virus (HCV) Hepacivirus, Flaviviridae Human Endemic Sexual Contact; Contact: Blood; Vertical transmission Primary: Liver image [hepatocyte image]
Persistence: (Chronic) Liver image [hepatocyte image]
Hepatitis6%
[Cirrhosis]
[Cryoglobulinemia]
- Oncovirus-
[Hepatocellular carcinoma]22%
[Chronic liver disease]
 Not available PEG interferon, Ribavirin, Direct-acting-Antivirals: RNA pol inhibitors, NS5A inhibitors, NS3/4A protease inhibitor GCF_000861845 NC_004102 Proteome
Hepatitis E virus (HEV) Hepevirus, Unassigned Pig, Monkey, Rodent, Human Endemic Fecal-oral Liver image [hepatocyte image], Nervous system, Immune system image, Pancreas image
Hepatitis0,05%?
[Chronic liver disease]
[Fulminent liver failure]
[Cryoglobulinemia]
 (China) Hepatitis E virus vaccine GCF_000861105 NC_001434 Proteome
Hepatitis delta virus (HDV) Deltavirus, Unassigned Human Endemic, satellite virus of HBV Sexual contact, blood Liver image [hepatocyte image]
Persistence: (Chronic) Liver image [hepatocyte image]
(HBV co-infection) HepatitisIncreased compared to HBV alone
(HBV co-infection) [Hepatocellular carcinoma]Increased compared to HBV alone
(HBV co-infection) [Fulminent liver failure]Increased compared to HBV alone
 Hepatitis B vaccine [Subunit, Injection (IM) (3)] GCF_000856565 NC_001653 Proteome
Human adenovirus (HAdV)
Subgroups A-G
image		 Mastadenovirus, Adenoviridae Human Seasonal (Winter), Endemic Worldwide Respiratory aerosols, fomites, fecal-oral (subgroup B, C, E): Pharynx image [Nasopharyngeal epithelial cell image], Lung image [Epithelial cell of lung image]
(Subgroup B): Urethra image,
(Subgroups A, F, G): Intestinal epithelium image "Intestinal epithelial cell image]
(Subgroups D): Cornea image [Corneal epithelial cell image]
Persistence: (Latency) (Serogroup C): Adenoid and tonsil
(subgroup B, C, E): Upper respiratory infection (URI) (species HAdV-A, B, C and E)
(Subgroups A, F, G): Gastroenteritis (HAdV-A, F and G)
(subgroup B): [Lower respiratory infection (LRI)]
(subgroup B): [Acute respiratory distress syndrome (ARDS)](Children: 0,4%)
(Subgroup D): [conjunctivitis (HAdV-B, D and E)]
[Encephalitis]
[Myocarditis]
 Adenovirus vaccine (serotype E(4), B(7)) [Attenuated, Oral (1)] Cidofovir GCF_000845085 NC_001405 Proteome
Human astrovirus (HAtV) Mamastrovirus, Astroviridae Human Seasonal (Winter), Endemic Fecal-oral Gastrointestinal tract image [Intestinal epithelial cell image, Enterocyte image]
Gastroenteritis0%
[Encephalitis]Unknown
 Not available GCF_000861865 NC_001943 Proteome
Human coronavirus (HCoV) Alphacoronavirus (species 229E and NL63), Betacoronavirus (species OC43 and HKU1), Coronaviridae Human, Bat (NL63) Seasonal (Winter), Endemic Respiratory Respiratory tract image [Respiratory epithelial cell], Immune system image [Macrophage image]
Upper respiratory infection (URI)0%
(Children) Lower respiratory infection (LRI)
[Bronchiolitis, Pneumonia]
[Acute respiratory distress syndrome (ARDS)]
 Not available GCF_000853505 NC_002645 Proteome
Human cytomegalovirus (HCMV) image Cytomegalovirus, Herpesviridae Human Endemic Worldwide Contact: Saliva, Urine, Breastmilk; Sexual contact: Genital secretions; Vertical transmission Primary: Respiratory tract Epithelium [Epithelial cells], Immune system image [Neutrophil image, Macrophage image, Monocytes image] image,
-First viremia
Secondary: lung, hepatocytes, tubular and glomerular kidney cells, splenic red pulp cells, pancreatic acinar cells, Endothelium image [Endothelial cell image], [Fibroblasts], Muscle image [Smooth muscle cell image], Salivary glands image, breasts, Placenta image [Extravillous trophoblasts image ]
Persistence: (Latency) Immune system image [Neutrophil image, Macrophage image, Monocytes image]
Mild0% (Congenital infection 0.001%)
[(Immunocompromised):Retinitis]
[(Immunocompromised):Mononucleosis]
[(Immunocompromised):Pneumonia]
[(Immunocompromised):Acute transverse myelitis (ascending myelitis)]
- Oncovirus?-
Mucoepidermoid carcinoma?
 Not available (Cytomegalovirus vaccine) (Acyclovir, Foscarnet) GCF_000845245 NC_001347 Proteome
Human enterovirus D68 (EV-D68), 70 (EV-70) image Enterovirus, Picornaviridae Human Seasonal (Spring/Summer), Endemic Fecal-oral Lower respiratory tract [Bronchial epithelial cells]
Lower respiratory infection (LRI)0%
[(Children) Bronchiolitis]
[Pneumonia]
[Acute respiratory distress syndrome (ARDS)]0,5%
[Acute flaccid myelitis]
 Not available GCF_000861205 NC_001430 Proteome
Human herpesvirus 1 (HHV-1) Simplexvirus, Herpesviridae Human Endemic Sexual contact, saliva Primary: Mouth mucosa image [Oral mucosa squamous cell image], Upper respiratory tract image [Epithelial cells]
Secondary: Lung image [Epithelial cell of lung image], Skin image [Keratinocytes image]
-Viremia
Secondary: Nervous system image [Neuron image]
Persistence: (latency) Nervous system image [Neuron image]
Mild, Cold sore0% (Congenital infection 8%)
Upper respiratory infection (URI)0%
[Acute transverse myelitis (ascending myelitis)]
[Pneumonia]
[Encephalitis]
 Not available (Acyclovir, Foscarnet) GCF_000859985 NC_001806 Proteome
Human herpesvirus 2 (HHV-2) Simplexvirus, Herpesviridae Human Endemic Sexual contact; Contact: saliva; Vertical transmission Primary: Genital tissue image [Epithelial cells]
-Viremia
Secondary: Nervous system image [Neuron image]
Persistence: (latency) Nervous system image [Neuron image]
Genital herpes0% (Congenital infection 8%)
[(Newborn, immunocompromized): Encephalitis]
 Not available (Acyclovir, Foscarnet) GCF_000858385 NC_001798 Proteome
Human herpesvirus 6 (HHV-6) Roseolovirus, Herpesviridae Human Endemic Contact: Saliva Primary: Immune system image [T-lymphocytes? image]
-Viremia
Secondary: Salivary glands image
Persistence: (Latency) Immune system image [T-lymphocytes? image]
Skin lesions0%
(Children) Roseola0%
[(Children) Encephalitis]
 Not available GCF_000845685 NC_001664 Proteome
Human herpesvirus 7 (HHV-7) Roseolovirus, Herpesviridae Human Endemic Respiratory, contact Primary: Immune system image [T-lymphocytes? image]
-Viremia
Secondary: Salivary glands image
Persistence: (Latency) Immune system image [T-lymphocytes? image]
Skin lesions0%
(Children) Roseola0%
[(Children) Encephalitis]0%
 Not available GCF_000848125 NC_001716 Proteome
Human herpesvirus 8 (HHV-8), Kaposi's sarcoma-associated herpesvirus (KSHV) Rhadinovirus, Herpesviridae Human Endemic Sexual contact, saliva, mosquito bite Immune system image [B-lymphocyte image, Monocytes image] Endothelial cell image, Keratinocytes image, Epithelium image [Epithelial cells], Salivary glands image, (HIV infected: Nervous system image [Neuron image])
[Cryoglobulinemia]
[Kaposi's sarcoma]20-50%
[Primary effusion lymphoma]80%
[Multicentric Castelman's disease]30%
 Not available GCF_000838265 NC_009333 Proteome
Human immunodeficiency virus (HIV-1, HIV-2) Lentivirus, Retroviridae Human Endemic Sexual contact; Contact: Blood; Vertical transmission Immune system image [T-lymphocytes? image, Macrophage image]
Persistence: (Latency) Immune system image [T-lymphocytes? image, Macrophage image]
AIDS75% [10 years] (Treated: 25% [10 years])
Not available GCF_000864765 NC_001802 Proteome
Human metapneumovirus (HMPV) Metapneumovirus, Pneumoviridae Human Endemic Respiratory Upper respiratory tract image Bronchioles image [Bronchiole epithelium cells], Pulmonary alveolus image [type I pneumocytes image, Alveolar macrophage image]
Upper respiratory infection (URI)0%
[Acute respiratory distress syndrome (ARDS)](Hospitalized adult 5%)
 Not available GCF_000865625 NC_004148 Proteome
Human papillomavirus (HPV) Papillomaviridae Human Endemic Contact, Sexual contact, Vertical transmission Cutaneous HPV (Alpha, Beta, Gamma Mu and Nu papillomavirus: Skin image [Basal cell of epidermis image], Mucosal HPV (Alphapapillomavirus): Mouth mucosa image [Oral mucosa squamous cell image], Genital mucosa image [Vagina squamous cell image]
Persistence: (Latency) basal or germ cells of the epidermis
Warts0%
[(HPV-13, 32: Epithelial hyperplasia))]0%
[Cryoglobulinemia]
- Oncovirus-
[(HPV:-16, 18, 31, 45 Cervical cancer)]50%
[(HPV-16: Oropharyngeal cancer)]
[(TMC6, TMC8 or CIB1 genetic defect; HPV-5, 8: Epidermodysplasia verruciformis image)]
 HPV vaccine [(HPV-16 and 18) Subunit, Injection (IM) (2)] None GCF_000863945 NC_001526 Proteome
Human parainfluenzavirus 1 (HPIV-1) and 3 (HPIV-3)
(Human Respirovirus 1 and 3)		 Respirovirus, Paramyxoviridae Human Seasonal (HPIV-1 Fall, HPIV-3 Summer), Endemic Respiratory Upper respiratory tract image [Epithelial cells, Olfactory epithelial cells image], Lung image [Epithelial cell of lung image, type I pneumocytes image, and type II pneumocytes image]
Upper respiratory infection (URI)(Hospitalized children <5 years: 5%)
[(children) (HPIV-1 Croup)]
[(children) (HPIV-3) Bronchiolitis]
[(children) (HPIV-3 Bronchitis]
[(children) (HPIV-3) Pneumonia]
[(children) (HPIV-3) Acute respiratory distress syndrome (ARDS))]
 Not available GCF_000848705 NC_003461 Proteome
Human parainfluenzavirus 2 (HPIV-2) and 4 (HPIV-4)
(Human Rubulavirus 2 and 4)		 Orthorubulavirus, Paramyxoviridae Human Respiratory Seasonal (Fall-Winter), Endemic trachea epithelial cells
Upper respiratory infection (URI)(Hospitalized children <5 years: 5%)
[(children) (HPIV-2 Croup)]
 Not available GCF_000863525 NC_003443 Proteome
Human parvovirus B19 (PVB-19) image Erythrovirus, Parvoviridae Human Partly seasonal (Spring), Endemic Respiratory; Vertical transmission Bone marrow image [Erythroid progenitor cells image, Myocardial endothelial cells, Monocytes image], (Abortive: Skin [Delmal fibroblast image])
Persistence: (Latency) Spleen image, lymph node image, tonsils, liver, heart, synovial tissues, Skin, Brain image, and testes)
(Children: Erythema infectiosum)0%
(Pregnancy: Hydrops fetalis)6% fetal death
 Not available GCF_000839645 NC_000883 Proteome
Human bocavirus (HBoV) Bocaparvovirus, Parvoviridae Human Endemic Respiratory, fecal?oral? Upper respiratory tract image
HBoV1: Upper respiratory infection (URI)0%
[Bronchiolitis]0%
[Pneumonia](ICU: 30-50%)
(Children, HBoV2, HBoV3, and HBoV4: Gastroenteritis)
 Not available GCF_000866725 NC_007455 Proteome
Respiratory syncytial virus (RSV) image Orthopneumovirus, Pneumoviridae Human Seasonal (Fall-Winter), Endemic Respiratory aerosols Primary: upper respiratory epithelium
Secondary: lower respiratory epithelium, Immune system image [Alveolar macrophage image], Immune system image [Dendritic cells image]
Lower respiratory infection (LRI)
[Bronchiolitis]
[Pneumonia](Children 0.2%, )(Hospitalized elder>65 11%)
[Acute respiratory distress syndrome (ARDS)]
 RSV vaccine [(Adult> 60 years, Maternal vaccination) Subunit, Injection (IM) (1)]
[(Children) Monoclonal antibody : Nirsevimab]		 GCF_000855545 NC_001781 Proteome
Human rhinovirus A, B, C (HRV) ECDC Enterovirus Human Seasonal (early autumn, late spring in temperate zones), Endemic Worldwide Respiratory aerosols, Contact: Fomites Respiratory tract image [Respiratory epithelial cell image]
Upper respiratory infection (URI)
[Pneumonia](Hospitalized elder>65 12%)
[Acute respiratory distress syndrome (ARDS)]
 Not available None GCF_000862245 NC_001617 Proteome
Human SARS coronavirus 1 (SARS-CoV) Betacoronavirus, Coronaviridae Bat, [Human, Palm civet] Sporadic, [Outbreak] Zoonosis, Respiratory Lung image, Pulmonary alveolus image [type I pneumocytes image, type II pneumocytes image] and Gastrointestinal tract image [surface enterocytes in the small bowel image]
[Acute respiratory distress syndrome (ARDS)]9% (Elder >65 50%)
[Post-viral fatigue syndrome (PVFS)]
 GCF_000864885 NC_004718 Proteome
Human foamy virus (HFV) Simiispumavirus, Retroviridae Primate, [Human] Sporadic Zoonosis, Contact, saliva Unknown
None0%
 GCF_003032765 NC_039025 Proteome
Human T-lymphotropic virus (HTLV) Deltaretrovirus, Retroviridae Human Endemic Asia (Japan, Caribbean), Africa Sexual contact; Contact: Blood; Vertical transmission Primary: Immune system image [T-lymphocytes image]
Persistence: (Latency) Immune system image [T-lymphocytes image]
HTLV-2: no symptoms0%
HTLV-1: Myelopathy/tropical spastic paraparesis0%
- Oncovirus-
HTLV-1: Adult T-cell leukemia/lymphoma20% [4 years]
 Not available Prosultiamine, Azacitidine, Tenofovir GCF_000863585 NC_001436 Proteome
Human torovirus (HToV) Torovirus, Coronaviridae Human Endemic Fecal-oral Gastrointestinal tract image
Gastroenteritis0%
 Not available NA NA NA
Human Influenza A virus (IAV)
+H1N1
+H2N2
+H3N2
+H1N2		 Influenzavirus A, Orthomyxoviridae (H1N1, H2N2, H3N2:+Human+, Pig)
(H1N2: Pig, Birds, [Human]		 (H1N1, H3N2: Seasonal (Winter), Endemic)
<(H1N2: Zoonosis, outbreaks)
(H2N2: Extinct)		 Respiratory aerosols Primary: Upper respiratory tract image (Nasopharynx image, [Epithelial cells]), Lower respiratory tract image (Trachea image, Bronchus image, [Ciliated epithelial cell image])
Secondary: Lower respiratory tract image, Pulmonary alveolus image [Ciliated bronchiolar epithelial cells, type I pneumocytes image, less frequently type II pneumocytes image]
Viremia (rare)
Tertiary: myotubes?
The flu: Upper respiratory infection (URI), Lower respiratory infection (LRI)
[Pneumonia -> ARDS](Hospitalized elder>65 11%)
[Myopathy]
[Myocarditis]
0.11/100,000 (1991) [(Children, Aspirin) Reye syndrome](Children: 21%)
4/100,000 [(Children) Encephalitis]18%
[(H1N1) Post-viral fatigue syndrome (PVFS)]
 Influenza vaccine [(Influenza A(H1N1, H3N2) and B/Victoria) Seasonal, Attenuated or Inactivated, Injection (1) or Nasal spray] GCF_000865725 NA Proteome
Avian Influenza A virus (IAV)
+ H5N1 (HPAI, LPAI)
+ H7N2 (LPAI)
+ H7N7 (HPAI, LPAI)
+ H7N9 (HPAI)
+ H9N2 (LPAI)		 Influenzavirus A, Orthomyxoviridae Bird, [Human, Pig] Sporadic, Outbreaks (H5N1: 45/year)
(H7N2: <1/year)
(H7N7: <1/year)
(H7N9: 1-800/year)
(H9N2: 4/year) 		Worldwide Zoonosis, animal contact
[(HPAI H5 or H7): Conjunctivitis]0%
Lower respiratory infection (LRI)
(HPAI H5 or H7): Pneumonia -> ARDS(H5N1: 52%)
(H7N7: 1%)
(H7N9: 30% )
Influenza H5N1 vaccine [Inactivated, Injection (IM) (2)] (Oseltamivir, Zanamivir, Peramivir, Baloxavir marboxil) GCF_000864105 NA Proteome
Human Influenza B virus (IBV) Influenzavirus B, Orthomyxoviridae Human, Pig, Seal Seasonal (Winter), Endemic [B/Yamagata extinct 2021] Respiratory Respiratory tract image [Respiratory epithelial cell]
Upper respiratory infection (URI)
Lower respiratory infection (LRI)
Flu
Pneumonia(Hospitalized elder>65 11%)
 Influenza vaccine [(Influenza A(H1N1, H3N2) and B/Victoria) Seasonal, Attenuated or Inactivated, Injection or Nasal spray] GCF_000820495 NA Proteome
Influenza C virus (ICV) Influenzavirus C, Orthomyxoviridae Human, Pig Seasonal (Winter), Endemic Respiratory Respiratory tract image [Respiratory epithelial cell]
Mild, Upper respiratory infection (URI)0%
(Children: Lower respiratory infection (LRI))?
 Not available GCF_000856665 NA Proteome
Isfahan virus (ISFV) Vesiculovirus, Rhabdoviridae Gerbil, Sandflies, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Unknown
Mild0%
 GCF_000906835 NC_020806 Proteome
JC polyomavirus (JCPyV or JCV) Polyomavirus, Polyomaviridae Human Endemic Worldwide Prevalence: 60% Respiratory, Contact: Fecal-oral or urine Primary: Tonsil image, Immune system image [B-lymphocyte]
-Viremia
Secondary: Kidney image [Tubular epithelial cell image], Bone marrow image
Reactivation (Immunodeficiency): Nervous system image [Oligodendrocytes, Astrocytes],
Persistence: (Latency) Kidney image [Tubular epithelial cell image], Bone marrow image
Asymptomatic30-50%
[(Immunodeficiency: Progressive multifocal leukoencephalopathy)30-50%]
 None None GCF_000863805 NC_001699 Proteome
Japanese encephalitis virus (JEV) Orthoflavivirus, Flaviviridae Bird, Culex mosquito, Pig, [Human, horses] Outbreak Incidence: 20000-30000/year (2013) Zoonosis, Arbovirus, arthropod bite Immune system image [Dendritic cells image], Nervous system image [Neuron image]
Asymptomatic0%
Encephalitis30%
 JEV vaccine [Injection (IM) (2); Intradermal (ID) (2)] GCF_000862145 NC_001437 Proteome
Junin arenavirus (JUNV) Arenavirus, Arenaviridae Rodent, [Human] Sporadic Zoonosis, fomite Immune system image [Macrophage image]
Argentine hemorrhagic fever15-30%
 GCF_000856545 NA Proteome
KI Polyomavirus (KIPyV) Polyomavirus, Polyomaviridae Human Endemic Respiratory Lung image [Alveolar macrophage image], Tonsil image
None0%
 GCF_000873085 NC_009238 Proteome
Lake Victoria marburgvirus (MARV) Marburgvirus, Filoviridae Bat, [Human, Monkeys] Outbreak Zoonosis, fomite Primary: Immune system image [Dendritic cells image, Macrophage image]
Secondary: Endothelial cell image and epithelial cells
Marburg virus disease; Hemorrhagic fever80%
 Monoclonal antibodies, Remdesivir GCF_000857325 NC_001608 Proteome
Tick-borne encephalitis virus (TBEV)
(+Powassan virus (POWV), Kyasanur Forest disease virus (KFDV), Alkhurma virus (ALKV), and Omsk hemorrhagic fever virus (OHFV))		 Flavivirus, Flaviviridae Bank vole, Yellow-necked mouse, small rodents?, Tick, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Skin dendritic (or Langerhans cell image) cells (DCs)
Secondary: migratory DCs and Macrophage image, neurons, Astrocytes
Mild (fever, fatigue, headache, muscular ache and nausea)0%
Aseptic Meningitis
Tick-borne encephalitis, Encephalitis0.5-2%
 GCF_000863125 NC_001672 Proteome
Lassa virus (LASV) Arenavirus, Arenaviridae Rodent, [Human] Outbreak Zoonosis, urine, fomites Immune system image [Dendritic cells], Liver image
Mild, Asymptomatic0%
Hemorrhagic fever15?20%
 Ribavirin GCF_000851705 NA Proteome
Lymphocytic choriomeningitis virus (LCMV) Arenavirus, Arenaviridae Rodent, [Human] Sporadic, [Outbreak] Zoonosis, fomite Immune system image [Dendritic cells image]
Mild0%%
[Aseptic meningitis]<1%
[Encephalitis]<1%
[Meningoencephalitis]<1%
[(Congenital: abortion, malformations)]30%
 GCF_000851025 NA Proteome
Machupo virus (MACV) Arenavirus, Arenaviridae Rodent, [Human] Sporadic Zoonosis, fomite Unknown
[Bolivian hemorrhagic fever = Hemorrhagic fever]5-30%
 GCF_000853725 NA Proteome
Mayaro virus (MAYV) Alphavirus, Togaviridae Primate, Aedes mosquito, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Nervous system image [Neuron image, Astrocytes image]
Mild (Fever, joint pain)<0%
 GCF_000863385 NC_003417 Proteome
MERS coronavirus (MERS-CoV) Betacoronavirus, Coronaviridae Tomb bat, [Human, Camel] Sporadic Zoonosis Lower respiratory tract [Nonciliated bronchial epithelial cells]
Lower respiratory infection (LRI)
Middle East respiratory syndrome35%
 GCF_000901155 NC_019843 Proteome
Measles virus (MV) image Morbilivirus, Paramyxoviridae Human Seasonal (Winter)(temperate countries)Endemic Incidence: 9 million/year (2022) Respiratory aerosols Primary: Immune system image, lymph node image, [Dendritic cells image, Macrophage image, B-lymphocyte, T-lymphocytes];
-Viremia
Secondary: Respiratory tract image [Respiratory epithelial cell], Spleen image, Gastrointestinal tract image [Intestinal epithelial cell image], Skin image [Keratinocytes image], Thymus image, Nervous system image [Neuron image]
Persistence: (Latency) Brain image [Neuron image]
Mild (cough, fever, conjunctivitis, maculopapular rash)0%
Immune amnesia0%
10/10000 [Pneumonia]30%
2/10000 [Subacute sclerosing panencephalitis]95% [3 years]
Measles vaccine [(MMR) Attenuated, Injection (IM) (2)] GCF_000854845 NC_001498 Proteome
Merkel cell polyomavirus (MCPyV or MCV) Polyomavirus, Polyomaviridae Human Endemic Respiratory? Skin, image, respiratory and Gastrointestinal tract image [Intestinal epithelial cell image]
- Oncovirus-
Merkel cell carcinoma35% [5 years]
 GCF_000874865 NC_010277 Proteome
Mokola virus (MOKV) +Lagos bat virus (LBV)
+ Shimoni bat virus (SHIBV) 		Lyssavirus, Rhabdoviridae Unknown, Rodent, [Human, Cat, Dog] Sporadic Zoonosis, Animal bite Primary: Peripheral nervous system image [Neuron image], Skeletal muscle?
Secondary: Central nervous system image [Neuron image, Astrocytes image], Salivary glands image [Myoepithelial cell image]
Fatal encephalitis100%
 Not available GCF_000856485 NC_006429 Proteome
Molluscum contagiosum virus Molluscipoxvirus, Poxviridae Human Endemic Contact Skin, image [Basal keratinocytes image]
(Skin lesions = Molluscum contagiosum)0%
 GCF_000843325 NC_001731 Proteome
Monkeypox virus (Mpox) (MPXV) Orthopoxvirus Unknown, Rodent, Human (Clade I, IIa: Sporadic, [Outbreak])
(Clade IIB: Endemic)		 (Clade I(2024): 16,000)
(Clade IIb(2022): 92,167)		 (Clade I: Central Africa)
(Clade IIa: West Africa)
(Clade IIb: worldwide (2022-)		 Zoonosis, contact Primary: Immune system image [Dendritic cells image, Macrophage image], lymph node image
Secondary: Skin, image [Delmal fibroblast image, Langerhans cell image]
Mild: Skin ulcers, Fever, Lymphadenopathy(clade I: 3.6%)
(clade IIb: 0.03%)
 Monkeypox vaccine [Attenuated, Injection (ID) (1) or Inactivated, Injection (ID) (2)] GCF_014621545 NC_063383 Proteome
Mumps virus (MuV) image Rubulavirus, Paramyxoviridae Human Endemic Respiratory, saliva Respiratory tract image [Respiratory epithelial cell], Glandular tissue: image Parotid gland image, Pancreas image, Kidney image image, Ovary image, Mammary gland image, Nervous system image
Mumps0,02%
Parotitis0%
[Orchitis]0%
[Oophoritis]0%
[Pancreatitis]0%
[Aseptic meningitis]0%
[Encephalitis]1%
[Sensorineural hearing loss]0%
 Mumps vaccine [(MMR) Attenuated, Injection (IM) (2)] GCF_000856685 NC_002200 Proteome
Murray valley encephalitis virus (MVE) Flavivirus Bird, Culex mosquito, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Immune system? image
Asymptomatic
[Encephalitis]25%
 GCF_000863565 NC_000943 Proteome
Nipah virus (NiV) Henipavirus, Paramyxoviridae Bat, [Human, primates, Pig, horses, cats, dogs, Rodent] Sporadic Zoonosis, Animal bite Respiratory tract image [Respiratory epithelial cell], Endothelial cell image and Nervous system image [Olfactory receptor cell, Neuron image], Kidney, Spleen
Encephalitis40-75%
 GCF_000863625 NC_002728 Proteome
Langya virus (LayV) Henipavirus, Paramyxoviridae Shrew, [Human] Zoonosis
fever, fatigue, and cough0%
 GCA_031319335 OM101125 Proteome
Norovirus (NoV)
(+Norwalk virus,
+Desert shield virus,
+Hawaii virus,
+Lordsdale virus,
+Mexico virus,
+Snow Mountain virus,
+Southampton virus) image		 Norovirus, Caliciviridae Human Endemic Fecal-oral Gastrointestinal tract image [Tuft cell image], Immune system image [Dendritic cells image, B-lymphocyte image, T-lymphocyte image]
Gastroenteritis0.03% (>65 years 0.3-1.6%)
 Not available GCF_000864005 NC_001959 Proteome
O'nyong-nyong virus (ONNV) Alphavirus, Togaviridae Vertebrate, Anopheles Mosquito [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Skin image, Skeletal muscle, Joint tissue and Bone marrow image
Fever, joint pain0%
 GCF_000863005 NC_001512 Proteome
Orf virus (ORFV)) Parapoxvirus, Poxviridae Mammal, [Human] Sporadic Zoonosis, contact Skin image, Immune system image [Macrophage image]
Mild: Skin ulcers0%
[Lymphadenopathy]0%
 GCF_000844845 NC_005336 Proteome
Oropouche virus (OROV) Orthobunyavirus Sloths, Marsupials, Monkey, Birds, Culicoides, Aedes mosquito, Culex mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Nervous system image [Microglia image, Neuron image]
Fever, joint pain, Oropouche fever0%
[Meningoencephalitis]0%
 GCF_000853785 NA Proteome
Poliovirus (PV) image ECDC Enterovirus, Picornaviridae Human Endemic Fecal-oral Primary: Pharynx image [Nasopharyngeal epithelial cell image], Tonsil image, Gastrointestinal tract image [Intestinal epithelial cell image, Peyer's patch image]; cervical lymph node image, Mesenteric lymph node image;
Secondary: Nervous system image [Neuron image]
72% Asymptomatic0%
24% Minor illness0%
1-5% [Aseptic meningitis]0%
0.1-0.5% [Paralytic poliomyelitis](Children 2%), (Adult 15%)
[Post-viral fatigue syndrome (PVFS)]
 Poliovirus vaccine [Attenuated, Oral or Inactivated, Injection (IM) (4); Injection (ID) (4)] None GCF_000861165 NC_002058 Proteome
Punta toro phlebovirus (PTV) Phlebovirus, Phenuiviridae Vertebrate, Sandflies, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Unknown
Mild0%
[Acute febrile ilness]0%
 GCF_002815115 NA Proteome
Dar es Salaam virus (DeSV) Tanzavirus, Phenuiviridae Vertebrate?, Insect?, [Human] Sporadic Incidence <1/year, underreported Africa (Tanzania) Zoonosis, Arbovirus, arthropod bite Unknown
unknownunknown
 GCF_018595055 NA Proteome
Hantaan virus (HTNV)
(+ Seoul virus, Amur virus)		 Orthohantavirus, Bunyaviridae
(Old World Hantaviruses)		 Rodent, [Human] Sporadic Zoonosis, urine, saliva Endothelium image [Endothelial cell image], Kidney image [Tubular endothelial cell image, Glomerular endothelial cell image], Lung image [Lung microvascular endothelial cell image, Alveolar macrophage image], Spleen image [Sinusoidal lining cell image]
Hemorrhagic fever with renal syndrome (HFRS)10%
 GCF_000856085 NA Proteome
Puumala virus (PUUV)
(+Saaremaa virus, Dobrava virus)		 Hantavirus, Bunyavirus
"Old World Hantaviruses"		 Bank vole, [Human] Sporadic Zoonosis, urine, saliva Endothelium image [Endothelial cell image], Kidney image [Tubular endothelial cell image, Glomerular endothelial cell image], Lung image [Lung microvascular endothelial cell image, Alveolar macrophage image], Spleen image [Sinusoidal lining cell image]
Nephropathia Epidemica (NE)<0.1%
 GCF_000854405 NA Proteome
Sin Nombre virus (SNV)
(+Black Creek Canal virus, New York orthohantavirus, Monongahela virus)		 Orthohantavirus, Bunyavirus
( New World Hantaviruses)		 Rodent, [Human] Sporadic Zoonosis, urine, saliva Endothelium image [Endothelial cell image], Lung image [Lung microvascular endothelial cell image, Alveolar macrophage image], Heart image [cardiac blood vessel endothelial cell image], Liver image [Endothelial cell of hepatic sinusoid image, Kupffer cell image, Hepatocyte image], Kidney image [Glomerular endothelial cell image], Spleen image [Sinusoidal lining cell image], Immune system image [Dendritic cells image, Macrophage image]
Hantavirus cardiopulmonary syndrome (HCPS)35%
[Acute respiratory distress syndrome (ARDS)]90%
 NA NA NA
Rabies virus (RABV) image
+Aravan virus (ARAV)
+Duvenhage virus (DUVV)
+Australian bat lyssavirus (ABLV)
+European bat lyssavirus (EBLV)
+Irkut virus (IRKV)
+Khujand virus (KHUV)		 Lyssavirus, Rhabdoviridae Carnivorous mammal, Bat, [Human] Sporadic Worldwide Zoonosis, Animal bite Primary: Peripheral nervous system image [Neuron image], Skeletal muscle?
Secondary: Central nervous system image [Neuron image, Astrocytes image], Salivary glands image [Myoepithelial cell image]
Fatal encephalitis100%
 Rabies vaccine [Inactivated Injection (IM) (2+) or Injection (ID) (2+)] None GCF_000859625 NC_001542 Proteome
Rift valley fever virus (RVF) Phlebovirus, Phenuiviridae Bat, Aedes mosquito, Culex mosquito, [Human, Sheep, Cattle, Goats, and Camels] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite, body fluid contact Primary: Immune system image [Macrophage image, Dendritic cells image], Granulocyte
Secondary: Liver image, brain
Mild, Fever0%
[Retinitis]0%
1% [Meningoencephalitis]<0.1%
1% [Acute hepatitis withhemorrhage]50%
 GCF_000847345 NA Proteome
Rosavirus A (RoV-A) Rosavirus, Picornaviridae Rodent, [Human] Sporadic Gastrointestinal tract image Unknown
DiarrheaUnknown
 GCF_000918175 NC_024070 Proteome
Ross river virus (RRV) Alphavirus, Togaviridae Macropodidae, Aedes mosquito, Culex mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Muscle, Joint tissue
Mild0%
Ross river fever0%
[Polyarthritis]0%
[Post-viral fatigue syndrome (PVFS)]
 GCF_000862165 NC_001544 Proteome
Colorado tick fever virus (CTFV)
+California hare coltivirus (CTFV-Ca)
+Eyach virus (EYAV)
image 		Coltivirus, Reoviridae
Colorado tick fever (CTF) serogroup		 Rodents, Deer, Tick, [Human, Cattle] Sporadic Incidence: 6/year North America (CTFV): USA, Canada, Europe (EYAV) Zoonosis, Arbovirus, arthropod bite, Vertical transmission Bone marrow image [Erythroblast image], Spleen, brain
Persistence:[4-6 months] Bone marrow image [Erythroblast image]
Mild (biphasic fever)0%
65% Leukopenia, Thrombocytopaenia)0%
[Aseptic meningitis]
[Encephalitis]
[Hemorrhagic fever]
 None None GCF_000853265 NA Proteome
Rotavirus A (RV-A) image Rotavirus, Reoviridae Human Endemic Seasonal (Winter and spring in temperates area), Contact: Fecal-oral Gastrointestinal tract image [Intestinal epithelial cell image, Enterocyte image]
Mild0%
(Children: Gastroenteritis)(<5 years 0.4%)
 Rotavirus vaccine:, [Attenuated, Oral] None GCF_000880735 NA Proteome
Rotavirus B (RV-B) Rotavirus, Reoviridae Human Sporadic Seasonal (Winter and spring in temperates area), Fecal-oral Gastrointestinal tract image [Intestinal epithelial cell image, Enterocyte image]
Mild0%
(Children: Gastroenteritis)Unknown
 None GCF_000864245 NA Proteome
Rotavirus C (RV-C) Rotavirus, Reoviridae Pig, Human Sporadic Fecal-oral Gastrointestinal tract image [Intestinal epithelial cell image, Enterocyte image]
Mild0%
(Children: Gastroenteritis)Unknown
 GCF_000864225 NA Proteome
Rubella virus (RUBV) image Rubivirus, Togaviridae Human Seasonal (Spring), Endemic Worldwide Respiratory, Vertical transmission Respiratory tract image
Mild, Rash0%
Rubella< 0.1%
[3/10000 Thrombocytopenia]Unknown
[2/10000 Encephalitis]Unknown
(Congenital: Congenital rubella syndrome)33% [1 year]
 Rubella vaccine [(MMR) Attenuated, Injection (IM) (2)] None GCF_000863025 NC_001545 Proteome
Getah virus (GETV)
+Sagiyama virus		 Alphavirus, Togaviridae Vertebrate, Mosquito, [Human, Horse, Pig] Sporadic Zoonosis, Arbovirus, arthropod bite Unknown
UnknownUnknown
 GCA_002888735 AB032553 Proteome
Salivirus A (SalV-A) Salivirus, Picornaviridae Human Endemic? Fecal-oral? Gastrointestinal tract image
Gastroenteritis? Unknown
 GCF_000886535 NC_012957 Proteome
Sapporo virus (SaV) Sapovirus, Caliciviridae Human, Pig Endemic, Outbreaks Fecal-oral Gastrointestinal tract image
(Children: Gastroenteritis)Unknown
 Not available GCF_000855765 NC_006554 Proteome
Human SARS coronavirus 2 (SARS-CoV-2) Betacoronavirus, Coronaviridae Human, [Bat, pangolin] Endemic Respiratory Upper respiratory tract image [Epithelial cells, Olfactory epithelial cells image, Goblet cells image], Lower respiratory tract, Pulmonary alveolus image [type I pneumocytes image, type II pneumocytes image], Cornea image [Corneal epithelial cell image], Gastrointestinal tract image [Intestinal epithelial cell image, Enterocyte image], image, Pancreas image [alpha cell image and beta cell image], Kidney image and Heart image [Cardiomyocyte image]
Upper respiratory infection (URI)0%
Lower respiratory infection (LRI) = Covid-190.3-1%
[conjunctivitis]0%
[Acute respiratory distress syndrome (ARDS)]10-30%
[Post-viral fatigue syndrome (PVFS) (=Long COVID)]
 COVID-19 vaccines [mRNA, Injection (IM) (2)], [Adenovirus vector, Injection (IM) (2)], [Inactivated, Injection (IM) (2)], [Subunit, Injection (IM) (2)] GCF_009858895 NC_045512 Proteome
Semliki forest virus (SFV) Alphavirus, Togaviridae Bird, Hedgehog, Aedes mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Nervous system image /TD>
Mild (Fever, joint pain)0%
 GCF_000860285 NC_003215 Proteome
Sindbis virus (SINV) Alphavirus, Togaviridae Birds, Culex mosquito, Culiseta mosquito, [Human, Vertebrates] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Immune system image [Macrophage image] , Joint tissue image
Mild (Rash, Fever, joint pain) = Pogosta disease0%
[Polyarthritis]0%
 GCF_000860545 NC_001547 Proteome
Saint Louis encephalitis virus (SLEV) Flavivirus, Flaviviridae Bird, Culex mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Lung image, Spleen":https://en.wikipedia.org/wiki/Spleen image, Brain image
Asymptomatic
[Aseptic meningitis]0%
[(Elder):Encephalitis]10%-20%
 GCF_000866785 NC_007580 Proteome
Haseki tick virus (HSTV) unassigned genus, Flaviviridae Tick, [Human] Sporadic Unknown (very low) (<5/year) Zoonosis, Arbovirus, arthropod bite primary unknown
-Viremia
secondary Upper respiratory tract
Upper respiratory infection (URI) 0%
 MW808978
Torque teno virus (TTV) Alphatorquevirus, Anelloviridae Human Endemic Prevalence >50%, higher in Africa and Asia Fecal-oral, Sexual, Blood Primary:Gastrointestinal tract image, Small intestine image, Immune system image [T-lymphocyte image], Granulocyte
-Viremia
Secondary: Liver image [Hepatocyte image], Bone marrow image
Asymptomatic0%
(HBV or HCV co-infection) [Cirrhosis]unknown
(HBV or HCV co-infection) [Hepatitis?]unknown
 Not available None GCF_000857545 NC_002076 Proteome
Sandfly fever Naples phlebovirus (SFNV)
+ Sandfly fever Sicilian virus (SFSV)
+ Toscana virus (TOSV)
+Massilia virus (MASV)		 Phlebovirus, Phenuiviridae Phlebotomus sandflies, [Human] Seasonal (Summer), Outbreaks Zoonosis, Arbovirus, arthropod bite Unknown, (TOSV: Nervous system image)
Asymptomatic0%
Mild, Fever = Sandfly fever0%
[Encephalitis]0%
 GCF_000854285 NA Proteome
Uukuniemi virus (UUKV)
+ Zaliv Terpeniya virus (ZTV)		 Uukuvirus, Phenuiviridae Tick, Aedes mosquito , Bird, [Human] Zoonosis, Arbovirus, arthropod bite Primary: Immune system image [Dendritic cells image]
Unknown-
 GCF_000851865 NA Proteome
Dabie bandavirus
Severe fever with thrombocytopenia syndrome virus (SFTSV) 		Bandavirus, Phenuiviridae Vertebrate, Tick, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Immune system image [Macrophage image, B-lymphocyte]
Asymptomatic0%
Mild (Fever), Thrombocytopenia0%
{multi-organ dysfunction}(>50 years 15-30%)
 GCF_000897355 NA Proteome
Vaccinia virus (VACV or VV)
(+Horsepox virus)		 Orthopoxvirus, Poxviridae Human, mammals Vaccination, Sporadic Contact Skin image, Immune system image [Dendritic cells image, Macrophage image, Monocytes image, B-lymphocyte], activated T lymphocytes
Asymptomatic0%
(1960-70 US vaccine [0.2/10000 Eczema vaccinatum])0%
(1960-70 vaccine) [0.4/10000 Generalized vaccinia]0%
(1960-70 US vaccine) [0.03/10000 Post-vaccinial Encephalitis]30%
(1960-70 vaccine) [0.01/10000 Vaccinia necrosum (progressive vaccinia)]15%
 GCF_000860085 NC_006998 Proteome
Varicella-zoster virus (VZV) image Varicellovirus, Herpesviridae Human Endemic Respiratory; Contact; Vertical transmission Primary: Mouth mucosa image, Tonsil image
Secondary: Immune system image [T-lymphocyte image], Skin image [Epidermal cell image], Nervous system image [Neuron image],
Persistence: (Latency) Dorsal root ganglion image)
(Children: Mild Chickenpox (Rash, Fever, headache,..))0%
(Adult: Acute Chickenpox (Rash, Fever, headache,..))0%
[Bronchitis]0%
[32/10000 Shingles]0%
[25/10000 viral pneumonia or secondary Bacterial pneumonia](adult: 10-30%)
[0.1/10000 Encephalitis or Aseptic meningitis]10%
[Post-viral fatigue syndrome (PVFS)]
 Varicella vaccine [Attenuated, Injection] GCF_000858285 NC_001348 Proteome
Smallpox virus (Variola virus (VARV)) Orthopoxvirus, Poxviridae Human Extinct, Eradicated (1980) Respiratory, Contact: Fomites Primary: Mouth mucosa image, Upper respiratory tract image,
-First viremia
Secondary: Immune system image [Macrophage image], Endothelium image [Endothelial cell image]
-Second viremia
Tertiary: Skin image, Spleen image, Bone marrow image
90% Ordinary Smallpox (Rash, skin ulcer)0%
[(Children: 5-10% Malignant Smallpox = flat smallpox)]90%
[(Adult: 2% Hemorrhagic Smallpox)]100%
 Smallpox virus [Attenuated, Injection (ID) (1) or Inactivated, Injection (ID) (2)] Tecovirimat GCF_000859885 NC_001611 Proteome
Venezuelan equine encephalitis virus (VEEV) Alphavirus, Togaviridae Rodent, Culex mosquito, [Human, Horse] Sporadic Zoonosis, Arbovirus, arthropod bite Primary: Dendritic cells image, Immune system image [Dendritic cells image, Macrophage image, Langerhans cell image]
Secondary: Spleen image, Thymus image, Peyer's patch image, Pancreas image, Nervous system image
Mild (Fever, joint pain)0%
[10% Encephalitis]<1%
 GCF_000862105 NC_001449 Proteome
Indiana vesiculovirus (VSIV) Vesiculovirus, Rhabdoviridae Horse, Cattle, Pig, Sandflies, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, athropod bite Multiple organs including: Heart image, Immune system image [Macrophage image], Nervous system image
Mild (Fever, Headache, Myalgia)0%
[(Children):Encephalitis]Unknown
 GCF_000850045 NC_001560 Proteome
Western equine encephalitis virus (WEEV) Alphavirus, Togaviridae Vertebrates, mosquitoes, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Primary: Unknown
Secondary: Nervous system image [Neuron image]
Fever, joint pain0%
[(children: Encephalitis)]0%
 GCF_000850885 NC_003908 Proteome
WU polyomavirus (WUPyV) Polyomavirus, Polyomaviridae Human Endemic Respiratory Lung image [Alveolar macrophage image], Trachea image
Asymptomatic0%
 GCF_000870785 NC_009539 Proteome
West Nile virus (WNV) Flavivirus, Flaviviridae Birds, Culex mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Primary: Immune system image [Dendritic cells image, Langerhans cell image]
Secondary: Lymphocytes, image, Spleen image and Liver image, Nervous system image [Neuron image, Astrocytes image]
80% Asymptomatic or mild0%
19% Fever, headache, vomiting0%
1% Encephalitis or Aseptic meningitis10%
[Post-viral fatigue syndrome (PVFS)]
 GCF_000861085 NC_001563 Proteome
Yaba monkey tumor virus (YMTV) Orthopoxvirus, Poxviridae Monkeys, Mosquito, [Human] Sporadic Zoonosis, Arbovirus, arthropod bite Skin image, Immune system image
Histiocytomas0%
 GCF_000845705 NC_005179 Proteome
Tanapox virus (TANV)
+ Yaba-like disease virus (YLDV)		 Orthopoxvirus, Poxviridae Monkeys, Mosquito, [Human] Zoonosis, Arbovirus, arthropod bite Skin image, Immune system image
cutaneous lesions0%
 GCF_000847185 NC_002642 Proteome
Yellow fever virus (YFV) Flavivirus, Flaviviridae Monkeys, Aedes mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite Primary: Immune system image [Dendritic cells image, Macrophage image]
-First viremia
Secondary: Liver image [Hepatocyte image]
85% Mild (Fever, headache, chills, back pain,...)0%
[15% Hemorrhagic fever]20-50%
 Yellow fever vaccine [Attenuated Injection (ID) (1)] GCF_000857725 NC_002031 Proteome
Zika virus (ZIKV) Flavivirus, Flaviviridae Monkeys, Aedes mosquito, [Human] Sporadic, Outbreaks Zoonosis, Arbovirus, arthropod bite; Vertical transmission Immune system image [Dendritic cells image, Macrophage image], Keratinocytes image, Nervous system image [Neuron image, Astrocytes image], Placenta image [Extravillous trophoblasts image ]
60% Asymptomatic0%
40% Mild (Fever,...)0%
[1% (Elder: Guillain-Barre syndrome]5%
[(Congenital infection: Microcephaly and other malformations ]64%
GCF_000882815.3 NC_012532 Proteome