Virgaviridae (taxid:675071)
VIRION

Non-enveloped, rigid helical rods with a helical symmetry, about 20-25 nm in diameter with a central "canal". There may be one, two or three segments depending on the considered genus.
GENOME
Monopartite or segmented (depending on the considered genus), linear, ssRNA(+) genome. Genomic RNA displays a tRNA-like structure in 3', but no poly-A tail, except for some hordeiviruses which have an internal poly-A tract between the coding sequence and the tRNA-like structure.
GENE EXPRESSION
The virion RNA is infectious and serves as both the genome and viral messenger RNA. The RNA-1 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1 in most genera. The downstream genes encoding the movement protein, viral suppressor of RNA silencing (VSR) and capsid proteins are usually translated from subgenomic RNAs.
ENZYMES
REPLICATION
CYTOPLASMIC
- Virus penetrates into the host cell.
- Uncoating, and release of the viral genomic RNA into the cytoplasm.
- The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
- Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
- The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
- The RdRp recognizes internal subgenomic promoters on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNAs that will generate the capsid protein, movement protein and viral suppressor of RNA silencing (VSR).
- Virus assembly in the cytoplasm. Each segment (if multipartite) is encapsidated.
- Viral movement protein probably mediate virion cell-to-cell transfer.
Host-virus interaction
Suppression of RNA silencing
Soilborne wheat mosaic virus (furovirus) 19K protein suppresses RNA silencing .
P15 of peanut clump virus (pecluvirus) suppresses RNA silencing .
Barley stripe mosaic virus (hordeivirus)gamma-b protein suppresses RNA silencing .
Tobacco mosaic tobamovirus (tobamovirus)126-kDa small replicase subunit suppresses RNA silencing .
Tobacco rattle virus (tobravirus)16K protein suppresses RNA silencing
.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)129 entries grouped by protein
1 entry
Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (194 kDa protein) (RNA-directed RNA polymerase)
2 entries
Protein 2b (29.1 kDa protein)
1 entry
Replication protein alpha-A
41 entries
Capsid protein (Coat protein)
5 entries
Coat protein (Capsid protein)
2 entries
84 kDa readthrough protein (CP-RT)
27 entries
Movement protein (30 kDa protein) (Cell-to-cell transport protein)
1 entry
32 kDa protein
1 entry
Protein P39
1 entry
40 kDa protein
25 entries
Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA polymerase)
3 entries
Movement protein TGB1 (EC 3.6.4.-) (P51) (Triple gene block 1 protein) (TGBp1)
3 entries
Movement protein TGB2 (P14) (Triple gene block 2 protein) (TGBp2)
3 entries
Movement protein TGB3 (17 kDa protein) (Beta-C protein) (Triple gene block 3 protein) (TGBp3)
1 entry
16 kDa protein
4 entries
16 kDa protein
1 entry
23 kDa protein
2 entries
29 kDa protein
5 entries
Suppressor of RNA silencing (15kD cysteine rich protein) (P15)
Beet soil-borne virus taxid:46436
Protein | ModelArchive |
104K protein | ma-jd-viral-38864 |
19K protein | ma-jd-viral-23837 |
Beet virus Q taxid:71972
Bell pepper mottle virus taxid:368735
Protein | ModelArchive |
126 kDa replicase | ma-jd-viral-38457 |
Capsid protein | ma-jd-viral-23819 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27437 |
Replicase large subunit | ma-jd-viral-19492 |
Brugmansia mild mottle virus taxid:402399
Protein | ModelArchive |
125 kDa replicase | ma-jd-viral-38454 |
Capsid protein | ma-jd-viral-23823 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27443 |
Cactus mild mottle virus taxid:229030
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23806 |
Movement protein | ma-jd-viral-28533 |
Replicase | ma-jd-viral-38458 |
Clitoria yellow mottle virus taxid:1128119
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23802 |
Movement protein | ma-jd-viral-27454 |
Replicase | ma-jd-viral-38479 |
Colombian potato soil-borne virus taxid:1758139
Frangipani mosaic virus taxid:99585
Protein | ModelArchive |
129 kDa replicase | ma-jd-viral-38455 |
Capsid protein | ma-jd-viral-23803 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27447 |
Gentian ovary ringspot virus taxid:1920772
Hibiscus latent Fort Pierce virus taxid:233051
Protein | ModelArchive |
128 kDa replicase (128kDa protein) | ma-jd-viral-38465 |
31 kDa movement protein | ma-jd-viral-27449 |
Capsid protein | ma-jd-viral-23816 |
Hibiscus latent Singapore virus taxid:185955
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23825 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27444 |
Replicase | ma-jd-viral-38447 |
Indian peanut clump virus taxid:32629
Protein | ModelArchive |
15 kDa protein | ma-jd-viral-48753 |
Methyltransferase | ma-jd-viral-38448 |
Maracuja mosaic virus taxid:368736
Protein | ModelArchive |
126 kDa replicase | ma-jd-viral-38462 |
Capsid protein | ma-jd-viral-23810 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27453 |
Replicase large subunit | ma-jd-viral-19513 |
Oat golden stripe virus taxid:45103
Passion fruit mosaic virus taxid:1032457
Protein | ModelArchive |
125 kDa protein | ma-jd-viral-38480 |
Capsid protein | ma-jd-viral-23808 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27448 |
Plumeria mosaic virus taxid:1501716
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23807 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27442 |
Replicase small protein | ma-jd-viral-38477 |
Potato mop-top virus taxid:37128
Protein | ModelArchive |
8K protein (Cysteine-rich protein) | ma-jd-viral-42622 |
Potato mop-top virus (isolate Potato/Sweden/Sw) taxid:652839
Rattail cactus necrosis-associated virus taxid:1123754
Protein | ModelArchive |
128 kDa replication protein | ma-jd-viral-38453 |
Capsid protein | ma-jd-viral-23813 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-28534 |
Rehmannia mosaic virus taxid:425279
Protein | ModelArchive |
126 kDa protein | ma-jd-viral-38449 |
Capsid protein | ma-jd-viral-23821 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27439 |
Ribgrass mosaic virus taxid:51680
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23805 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27445 |
RNA replicase component | ma-jd-viral-38464 |
Soil-borne cereal mosaic virus taxid:100887
Tomato brown rugose fruit virus taxid:1761477
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23818 |
Tomato brown rugose fruit virus (isolate TOBRFV/Tomato/Jordan/Tom1-Jo/2015) taxid:2654645
Tomato mosaic virus taxid:12253
Tomato mosaic virus (strain L) taxid:12252
Tomato mottle mosaic virus taxid:1391702
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23822 |
Capsid protein | ma-jd-viral-23822 |
Methyltransferase/helicase | ma-jd-viral-38441 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27441 |
Tropical soda apple mosaic virus taxid:327387
Protein | ModelArchive |
125 kDa replicase | ma-jd-viral-38435 |
Capsid protein | ma-jd-viral-23824 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27440 |
Turnip vein-clearing virus taxid:29272
Yellow tailflower mild mottle virus taxid:1416026
Protein | ModelArchive |
129k replicase protein | ma-jd-viral-38478 |
Capsid protein | ma-jd-viral-23809 |
Movement protein (Cell-to-cell transport protein) | ma-jd-viral-27451 |
Youcai mosaic virus taxid:228578
Protein | ModelArchive |
Capsid protein | ma-jd-viral-23811 |
Capsid protein (Coat protein) | ma-jd-viral-23811 |
Movement protein (30 kDa protein) (Cell-to-cell transport protein) | ma-jd-viral-27438 |