Nucleorhabdovirus

VIRION

Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.

GENOME

Negative-stranded RNA linear genome, about 11-15 kb in size. Encodes for 5 to six proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

REPLICATION

IN PLANT:NUCLEAR

  1. Virus penetrates into the cell by effraction or plasmodesmata transport.
  2. Viral nucleocapsid is transported into the host nucleus
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid can penetrate in neighboring plant cells through plasmodesmata transport
  6. Alternatively the ribonucleocapsid can binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

IN INSECT:NUCLEAR

  1. Attachment of the viral G glycoproteins to host receptors.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Viral nucleocapsid is transported into the host nucleus
  4. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  5. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  6. The ribonucleocapsid binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

Host-virus interaction

Movement through plasmodesmata

Viral movement protein 3of RYSV presumably interacts with host plasmodesmata to allow tubule guided movement of viral genomic material from cell to cell without budding.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by strain (browse by keywords)

7 entries

Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain

Select_allDeselect_all
L_RYSV RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) ...
NCAP_RYSV Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
MVP_RYSV Movement protein (MP) (Cell-to-cell transport protein) (Protein 3)
MATRX_RYSV Matrix protein
GLYCO_RYSV Glycoprotein
PHOSP_RYSV Phosphoprotein (Protein P) (Protein M1)
VP6_RYSV Protein 6

6 entries

Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain

Select_allDeselect_all
L_MMVR RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) ...
NCAP_MMVR Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
MVP_MMVR Putative movement protein 3 (MP) (Cell-to-cell transport protein) (Protein 3)
GLYCO_MMVR Glycoprotein
MATRX_MMVR Matrix protein
PHOSP_MMVR Phosphoprotein (Protein P) (Protein M1)

6 entries

Sonchus yellow net virus (SYNV) reference strain

Select_allDeselect_all
MVP_SYNV Movement protein (MP) (Cell-to-cell transport protein) (Protein Sc4)
NCAP_SYNV Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
L_SYNV RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) ...
MATRX_SYNV Matrix protein (M2 protein)
GLYCO_SYNV Spike glycoprotein
PHOSP_SYNV Phosphoprotein (Protein P) (Protein M1)

6 entries

Taro vein chlorosis virus (TAVCV) reference strain

Select_allDeselect_all
L_TAVCV RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) ...
NCAP_TAVCV Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
MATRX_TAVCV Matrix protein
MVP_TAVCV Movement protein (MP) (Cell-to-cell transport protein) (Protein 3)
GLYCO_TAVCV Glycoprotein
PHOSP_TAVCV Phosphoprotein (Protein P) (Protein M1)