Almendravirus (taxid:1972682)

VIRION

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Enveloped, bullet shaped. About 50 nm in diameter and up to 190 nm long.

GENOME

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Negative-stranded RNA linear genome, about 12 kb in size. Encodes for six proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Attachment of the viral G glycoproteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid binds to the matrix protein and buds, releasing new virions.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Puerto Almendras virus taxid:1479613

Protein ModelArchive
G protein ma-jd-viral-56581
M protein ma-jd-viral-11544
Nucleoprotein (Nucleocapsid protein) ma-jd-viral-15141
P protein ma-jd-viral-44088
SH protein ma-jd-viral-59396