Reovirus fold/BTV fold

All capsid proteins have a common fold consisting of three to four domains:

-The N-term column runs from top to bottom and connects the other domains. It essentially consists of beta strands;

-The helix-rich domain consists mainly of alpha-helixes, which form the five-fold pore of the capsid. In many ghabrivirales it contains a loop having the cap-snatching catalytic activity.

-The middle domain varies in different order. In many ghabrivirales it supports the cap-snatching catalytic activity.

- The C-term domain consists mainly of beta-strands, except in mindivirales, which are mainly alpha-helixes. It is flexible and forms the three-fold axes and the two-fold axes of the icosahedral capsid.

Origin:

Viral

Topology

Reovirales