Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).


Linear, dsDNA genome of about 48 kb, containing about 70 genes.




  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

170 entries grouped by strain (browse by keywords)

All proteins are shown (view only 86 complete proteome entries)

61 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

RPC2_LAMBD Transcriptional activator II
SCAF_LAMBD Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
RPC1_LAMBD Repressor protein cI
RPC3_LAMBD Protease inhibitor III
PORTL_LAMBD Portal protein B (GpB) (Minor capsid protein B) [Cleaved into: Protein B*]
PP_LAMBD Serine/threonine-protein phosphatase (EC
REGN_LAMBD Antitermination protein N (Regulatory protein N) (PN)
REXB_LAMBD Protein rexB
SPAN1_LAMBD Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
SIEB_LAMBD Superinfection exclusion protein B
REXA_LAMBD Protein rexA
REGQ_LAMBD Antitermination protein Q
RCRO_LAMBD Regulatory protein cro
NIND_LAMBD Protein ninD
NINF_LAMBD Protein ninF
NINE_LAMBD Protein ninE (Nin60)
NING_LAMBD Protein ninG
NINB_LAMBD Protein ninB
NINH_LAMBD Protein ninH
RAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein)
COMPL_LAMBD Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
DECO_LAMBD Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)
EA31_LAMBD Protein ea31
CAPSD_LAMBD Major capsid protein (Gene product E) (gpE) (Major head protein)
HCP_LAMBD Head completion protein (HCP) (Head-tail joining protein W) (gpW)
G_LAMBD Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) ...
GT_LAMBD Tail assembly protein GT (Gene product GT) (gpGT) (Minor tail protein GT)
FI_LAMBD DNA-packaging protein FI
EXO_LAMBD Exonuclease (EC
GAM_LAMBD Host-nuclease inhibitor protein gam
FIBER_LAMBD Tail fiber protein (stf) (Gene product 27) (gp27)
FII_LAMBD Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)
HOLIN_LAMBD Antiholin (Lysis inhibitor S-107)
EA10_LAMBD Protein ea10
EA85_LAMBD Protein ea8.5
ENLYS_LAMBD Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)
EA22_LAMBD Protein ea22
EA47_LAMBD Protein ea47
EA59_LAMBD Protein ea59
VRPP_LAMBD Replication protein P
VLOM_LAMBD Outer membrane protein lom (ORF 206A)
VXIS_LAMBD Excisionase
SPAN2_LAMBD Spanin, outer lipoprotein subunit (o-spanin) (Outer membrane lipoprotein Rz1)
TIPI_LAMBD Tail tip assembly protein I
TIPJ_LAMBD Tip attachment protein J (Central tail fiber) (Host specificity protein J)
TIPM_LAMBD Tail tip protein M
TMP_LAMBD Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry ...
TERS_LAMBD Terminase small subunit (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)
TFA_LAMBD Tail fiber assembly protein
TTTP_LAMBD Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail ...
TUBE_LAMBD Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)
VREN_LAMBD Protein ren
VRPO_LAMBD Replication protein O
VBET_LAMBD Recombination protein bet
VKIL_LAMBD Protein kil
TIPK_LAMBD Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
TIPL_LAMBD Tail tip protein L
TERL_LAMBD Terminase, large subunit (EC (DNA-packaging protein A) (Large terminase protein) (gpA)
Y290_LAMBD Uncharacterized nin region protein ORF290
Y64_LAMBD Putative uncharacterized protein ORF64
VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)

20 entries

Bacillus phage SPP1 (Bacteriophage SPP1) reference strain

SCAF_BPSPP Capsid assembly scaffolding protein (Gene product 11) (Gp11) (Head morphogenesis protein) (Scaffold ...
PORTL_BPSPP Portal protein (Gene product 6) (gp6) (Portal vertex protein)
COMPL_BPSPP Tail completion protein gp17 (Gene product 17) (gp17) (Head-tail joining protein gp17) (Tail-to-head ...
DECO_BPSPP Decoration protein gp12 (Gene product 12) (gp12)
DIT_BPSPP Distal tail protein (Dit) (Gene product 19.1) (Gp19.1)
CAPSD_BPSPP Major capsid protein (Gene product 13) (gp13)
GP7_BPSPP Minor head protein GP7 (Accessory head protein gp7)
HCP15_BPSPP Head completion protein gp15 (HCP) (Connector protein gp15) (Gene product 15) (Gp15)
HCP16_BPSPP Head completion protein gp16 (Connector protein gp16) (Gene product 16) (Gp16) (Stopper protein ...
ENLYS_BPSPP Endolysin (EC 3.5.1.-) (LysSPP1) (Putative N-acetylmuramoyl-L-alanine amidase)
HOL26_BPSPP Putative antiholin
FIBER_BPSPP Tail spike protein (TSP) (Gene product 21) (Gp21)
HOL24_BPSPP Holin-like protein 24.1 (Gene product 24.1) (gp24.1)
TMP_BPSPP Tail tape measure protein gp18 (Gene product 18) (gp18)
YOR5_BPSPP Uncharacterized 10.3 kDa protein in GP2-GP6 intergenic region (ORF 5)
YOR3_BPSPP Uncharacterized 8.5 kDa protein in GP2-GP6 intergenic region (ORF 3)
YOR4_BPSPP Uncharacterized 10.2 kDa protein in GP2-GP6 intergenic region (ORF 4)
TUBE_BPSPP Tail tube protein gp17.1* (TTP) (Gene product 17.1) (gp17.1) (Major tail protein) (MTP)
TERL_BPSPP Terminase, large subunit gp2 (EC 3.1.-.-) (DNA-packaging protein G2P) (Gene product 2) (gp2)
TERS_BPSPP Terminase small subunit (G1P) (Terminase, small subunit gp1)

1 entry

Bacillus phage phi105 (Bacteriophage phi-105) reference strain

VLYS_BPPH1 Probable holin (Lysis protein)

2 entries

Bacillus phage phi3T (Bacteriophage phi-3T) reference strain

AIMP_BPPHT Protein AimP [Cleaved into: Arbitrium peptide]
AIMR_BPPHT AimR transcriptional regulator (Arbitrium communication peptide receptor)

2 entries

Enterobacteria phage HK97 (Bacteriophage HK97) reference strain

RUSA_BPHK7 Crossover junction endodeoxyribonuclease rusA (EC (Gp67) (Holliday junction nuclease rusA) ...
CAPSD_BPHK7 Major capsid protein (Gene product 5) (gp5) (Major head protein) [Cleaved into: Scaffolding domain ...

1 entry

Escherichia phage lambda (Bacteriophage lambda)

BOR_LAMBD Lipoprotein bor

17 entries

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

PORTL_BPP21 Portal protein (Head protein Gp4)
SPAN1_BPP21 Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
NINE_BPP21 Protein ninE
NINF_BPP21 Protein ninF
NINB_BPP21 Protein ninB
NING_BPP21 Protein ninG
LYS_BPP21 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)
CAPSD_BPP21 Major capsid protein (Gene product 7) (gp7) (Major head protein)
DECO_BPP21 Head decoration protein (Head protein GPshp)
HOLIN_BPP21 Antiholin
VXIS_BPP21 Excisionase
W_BPP21 Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining ...
VINT_BPP21 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
TERS_BPP21 Terminase, small subunit (Gp1)
YG78_BPP21 Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region
VG05_BPP21 Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5) [Cleaved into: Scaffold ...
TERL_BPP21 Terminase, large subunit gp2 (EC (DNA-packaging protein) (Gene product 2) (gp2)

14 entries

Bacillus phage phi105 (Bacteriophage phi-105)

RPC_BPPH1 Immunity repressor protein
IMMF_BPPH1 ImmF control region 10 kDa protein
YIM9_BPPH1 Putative uncharacterized immunity region protein 9
YIM6_BPPH1 Putative uncharacterized immunity region protein 6
YIMB_BPPH1 Putative uncharacterized immunity region protein 11
YIM8_BPPH1 Putative uncharacterized immunity region protein 8
YIMC_BPPH1 Uncharacterized immunity region protein 12
YIM5_BPPH1 Uncharacterized immunity region protein 5
YIMD_BPPH1 Uncharacterized immunity region protein 13
YIM2_BPPH1 Uncharacterized immunity region protein 2
YIM4_BPPH1 Putative uncharacterized immunity region protein 4
YIMA_BPPH1 Putative uncharacterized immunity region protein 10
YIM3_BPPH1 Uncharacterized immunity region protein 3
YIME_BPPH1 Uncharacterized immunity region protein 14

11 entries

Enterobacteria phage phi80 (Bacteriophage phi-80)

RPC1_BPPH8 Repressor protein CI
RPC2_BPPH8 Regulatory protein CII
REGN_BPPH8 Probable regulatory protein N
COR_BPPH8 Adsorption-inhibiting cor protein
CAPSD_BPPH8 Major capsid protein (Gene product 5) (gp5) (Gene product E) (gpE) (Major head protein)
VG14_BPPH8 Replication protein 14
VG40_BPPH8 Protein 40A
VG15_BPPH8 Replication protein 15
VG30_BPPH8 Gene 30 protein
VINT_BPPH8 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VXIS_BPPH8 Excisionase

9 entries

Escherichia phage HK022 (Bacteriophage HK022)

RPC1_BPHK0 26 kDa repressor protein (Regulatory protein CI)
RPC3_BPHK0 Regulatory protein CIII
REGQ_BPHK0 Antitermination protein
RCRO_BPHK0 8.4 kDa cro protein
VNUN_BPHK0 Transcription termination factor nun
YO48_BPHK0 Uncharacterized 5.8 kDa protein (ORF48)
VKIL_BPHK0 Protein kil
VINT_BPHK0 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VXIS_BPHK0 Excisionase

8 entries

Enterobacteria phage H19B (Bacteriophage H19B)

REGQ_BPH19 Antitermination protein Q
NINF_BPH19 Protein ninF
LYS_BPH19 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)
NINE_BPH19 Protein ninE
NING_BPH19 Protein ninG
NINH_BPH19 Protein ninH
STXA_BPH19 Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC (Verocytotoxin 1 ...
STXB_BPH19 Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) ...

7 entries

Enterobacteria phage 82 (Bacteriophage 82)

RUSA_BP82 Crossover junction endodeoxyribonuclease rusA (EC (Holliday junction nuclease rusA) ...
REGQ_BP82 Antitermination protein Q
NINE_BP82 Protein ninE
YLCH_BP82 Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)
YBCN_BP82 Uncharacterized protein in rusA 5'region (ORF151)
YBCO_BP82 Putative nuclease ybcO (EC 3.1.-.-)
YLCG_BP82 Uncharacterized protein in rusA 3'region (ORF45)

5 entries

Enterobacteria phage 434 (Bacteriophage 434)

RPC2_BP434 Regulatory protein CII
REXA_BP434 Protein rexA
RCRO_BP434 Regulatory protein cro (Antirepressor)
VXIS_BP434 Excisionase
VINT_BP434 Integrase (EC 2.7.7.-) (EC 3.1.-.-)

2 entries

Bacillus phage phi3T (Bacteriophage phi-3T)

MTBP_BPPHT Modification methylase Phi3TI (M.Phi3TI) (EC (Cytosine-specific methyltransferase Phi3TI)
TYSY_BPPHT Thymidylate synthase (TS) (TSase) (EC

2 entries

Enterobacteria phage HK97 (Bacteriophage HK97)

PORTL_BPHK7 Portal protein (GP3)
PRO_BPHK7 Prohead protease (GP4)

2 entries

Corynephage beta

DTXH_CORBE Diphtheria toxin homolog CRM228 [Cleaved into: Diphtheria toxin homolog CRM228 fragment A; ...
DTX_CORBE Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC [Cleaved into: ...

2 entries

Enterobacteria phage PA-2 (Bacteriophage PA-2)

LYS_BPPA2 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)
PORI_BPPA2 Outer membrane porin protein LC

1 entry

Bacillus phage SP02 (Bacteriophage SP02)

DPOL_BPSP2 DNA polymerase (EC (EC 3.1.11.-)

1 entry

Bacillus phage SPR (Bacteriophage SPR)

MTBS_BPSPR Modification methylase SPRI (M.SPRI) (EC (Cytosine-specific methyltransferase SPRI)

1 entry

Bacillus phage rho11s (Bacteriophage rho-11s)

MTBR_BPRH1 Modification methylase Rho11sI (M.Rho11sI) (EC (Bsu P11s) (Cytosine-specific ...

1 entry

Corynephage omega

DTX_COROM Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC [Cleaved into: ...