Lambdavirus

VIRION

Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).

GENOME

Linear, dsDNA genome of about 48 kb, containing about 70 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

108 entries grouped by strain (browse by keywords)

62 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

Select_allDeselect_all
VREN_LAMBD Protein ren
VBET_LAMBD Recombination protein bet
Y290_LAMBD Uncharacterized nin region protein ORF290
FIBER_LAMBD Tail fiber protein (stf) (Gene product 27) (gp27)
FII_LAMBD Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)
DECO_LAMBD Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)
FI_LAMBD DNA-packaging protein FI
TFA_LAMBD Tail fiber assembly protein
Y64_LAMBD Putative uncharacterized protein ORF64
VRPP_LAMBD Replication protein P
VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)
RAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein)
TMP_LAMBD Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry ...
REXA_LAMBD Protein rexA
TIPM_LAMBD Tail tip protein M
SPAN2_LAMBD Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
REXB_LAMBD Protein rexB
REGQ_LAMBD Antitermination protein Q
TIPJ_LAMBD Tip attachment protein J (Central tail fiber) (Host specificity protein J)
SIEB_LAMBD Superinfection exclusion protein B
RPC3_LAMBD Protease inhibitor III
NIND_LAMBD Protein ninD
RPC1_LAMBD Repressor protein cI
RCRO_LAMBD Regulatory protein cro
PORTL_LAMBD Portal protein B (GpB) (Minor capsid protein B) [Cleaved into: Protein B*]
REGN_LAMBD Antitermination protein N (Regulatory protein N) (PN)
RPC2_LAMBD Transcriptional activator II
PP_LAMBD Serine/threonine-protein phosphatase (EC 3.1.3.16)
G_LAMBD Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) ...
TIPI_LAMBD Tail tip assembly protein I
TIPL_LAMBD Tail tip protein L
TERS_LAMBD Terminase small subunit (EC 3.6.4.-) (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)
SPAN1_LAMBD Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
TUBE_LAMBD Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)
VKIL_LAMBD Protein kil
VXIS_LAMBD Excisionase
TIPK_LAMBD Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
TERL_LAMBD Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA) [Includes: ...
SCAF_LAMBD Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
VLOM_LAMBD Outer membrane protein lom (ORF 206A)
VRPO_LAMBD Replication protein O
TTTP_LAMBD Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail ...
GT_LAMBD Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)
NINE_LAMBD Protein ninE (Nin60)
NINB_LAMBD Protein ninB
NINH_LAMBD Protein ninH
NING_LAMBD Protein ninG
HOLIN_LAMBD Antiholin (Lysis inhibitor S-107)
NINF_LAMBD Protein ninF
EXO_LAMBD Exonuclease (EC 3.1.11.3)
EA59_LAMBD Protein ea59
COMPL_LAMBD Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
EA22_LAMBD Protein ea22
ENLYS_LAMBD Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)
EA85_LAMBD Protein ea8.5
GAM_LAMBD Host-nuclease inhibitor protein gam
EA47_LAMBD Protein ea47
EA31_LAMBD Protein ea31
HCP_LAMBD Head completion protein (HCP) (Head-tail joining protein W) (gpW)
CAPSD_LAMBD Major capsid protein (Gene product E) (gpE) (Major head protein)
EA10_LAMBD Protein ea10
BOR_LAMBD Lipoprotein bor

18 entries

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Select_allDeselect_all
VXIS_BPP21 Excisionase
VINT_BPP21 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VG05_BPP21 Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5) [Cleaved into: Scaffold ...
W_BPP21 Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining ...
NINE_BPP21 Protein ninE
SPAN1_BPP21 Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
NINB_BPP21 Protein ninB
SPAN2_BPP21 Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
TERL_BPP21 Terminase, large subunit (DNA-packaging protein gp2) (Gene product 2) (gp2) (Large terminase ...
HOLIN_BPP21 Antiholin
PORTL_BPP21 Portal protein B (GpB) (Minor capsid protein B)
YG78_BPP21 Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region
TERS_BPP21 Terminase, small subunit (Gp1)
CAPSD_BPP21 Major capsid protein (Gene product 7) (Gene product E) (gpE) (Major head protein)
NING_BPP21 Protein ninG
NINF_BPP21 Protein ninF
DECO_BPP21 Head decoration protein (Head protein GPshp)
ENLYS_BPP21 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)

8 entries

Enterobacteria phage H19B (Bacteriophage H19B)

Select_allDeselect_all
NINH_BPH19 Protein ninH
NINE_BPH19 Protein ninE
STXB_BPH19 Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) ...
REGQ_BPH19 Antitermination protein Q
STXA_BPH19 Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verocytotoxin 1 ...
NINF_BPH19 Protein ninF
NING_BPH19 Protein ninG
ENLYS_BPH19 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)

7 entries

Enterobacteria phage 82 (Bacteriophage 82)

Select_allDeselect_all
YBCN_BP82 Uncharacterized protein in rusA 5'region (ORF151)
YLCG_BP82 Uncharacterized protein in rusA 3'region (ORF45)
REGQ_BP82 Antitermination protein Q
YBCO_BP82 Putative nuclease ybcO (EC 3.1.-.-)
RUSA_BP82 Crossover junction endodeoxyribonuclease rusA (EC 3.1.22.4) (Holliday junction nuclease rusA) ...
YLCH_BP82 Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)
NINE_BP82 Protein ninE

5 entries

Enterobacteria phage 434 (Bacteriophage 434)

Select_allDeselect_all
VINT_BP434 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VXIS_BP434 Excisionase
REXA_BP434 Protein rexA
RCRO_BP434 Regulatory protein cro (Antirepressor)
RPC2_BP434 Regulatory protein CII

2 entries

Corynephage beta

Select_allDeselect_all
DTX_CORBE Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...
DTXH_CORBE Diphtheria toxin homolog CRM228 [Cleaved into: Diphtheria toxin homolog CRM228 fragment A; ...

2 entries

Enterobacteria phage PA-2 (Bacteriophage PA-2)

Select_allDeselect_all
PORI_BPPA2 Outer membrane porin protein LC
ENLYS_BPPA2 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)

1 entry

Bacillus phage SP02 (Bacteriophage SP02)

DPOL_BPSP2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

1 entry

Bacillus phage SPR (Bacteriophage SPR)

MTBS_BPSPR Modification methylase SPRI (M.SPRI) (EC 2.1.1.37) (Cytosine-specific methyltransferase SPRI)

1 entry

Bacillus phage rho11s (Bacteriophage rho-11s)

MTBR_BPRH1 Modification methylase Rho11sI (M.Rho11sI) (EC 2.1.1.37) (Bsu P11s) (Cytosine-specific ...

1 entry

Corynephage omega

DTX_COROM Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...