Lambdavirus

VIRION

Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).

GENOME

Linear, dsDNA genome of about 48 kb, containing about 70 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

108 entries grouped by strain (browse by keywords)

62 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

Select_allDeselect_all
G_LAMBD Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) ...
EA22_LAMBD Protein ea22
EA10_LAMBD Protein ea10
ENLYS_LAMBD Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)
RCRO_LAMBD Regulatory protein cro
RAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein)
REGN_LAMBD Antitermination protein N (Regulatory protein N) (PN)
EXO_LAMBD Exonuclease (EC 3.1.11.3)
DECO_LAMBD Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)
FII_LAMBD Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)
HCP_LAMBD Head completion protein (HCP) (Head-tail joining protein W) (gpW)
EA47_LAMBD Protein ea47
EA85_LAMBD Protein ea8.5
FIBER_LAMBD Tail fiber protein (stf) (Gene product 27) (gp27)
NIND_LAMBD Protein ninD
NINH_LAMBD Protein ninH
PORTL_LAMBD Portal protein B (GpB) (Minor capsid protein B) [Cleaved into: Protein B*]
NINE_LAMBD Protein ninE (Nin60)
PP_LAMBD Serine/threonine-protein phosphatase (EC 3.1.3.16)
CAPSD_LAMBD Major capsid protein (Gene product E) (gpE) (Major head protein)
GT_LAMBD Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)
EA31_LAMBD Protein ea31
EA59_LAMBD Protein ea59
FI_LAMBD DNA-packaging protein FI
COMPL_LAMBD Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
SCAF_LAMBD Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
RPC1_LAMBD Repressor protein cI
REXB_LAMBD Protein rexB
REGQ_LAMBD Antitermination protein Q
SPAN2_LAMBD Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
HOLIN_LAMBD Antiholin (Lysis inhibitor S-107)
GAM_LAMBD Host-nuclease inhibitor protein gam
RPC3_LAMBD Protease inhibitor III
RPC2_LAMBD Transcriptional activator II
TFA_LAMBD Tail fiber assembly protein
NING_LAMBD Protein ninG
NINB_LAMBD Protein ninB
SIEB_LAMBD Superinfection exclusion protein B
NINF_LAMBD Protein ninF
VRPP_LAMBD Replication protein P
TTTP_LAMBD Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail ...
TERL_LAMBD Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA) [Includes: ...
REXA_LAMBD Protein rexA
VREN_LAMBD Protein ren
VBET_LAMBD Recombination protein bet
TIPJ_LAMBD Tip attachment protein J (Central tail fiber) (Host specificity protein J)
TERS_LAMBD Terminase small subunit (EC 3.6.4.-) (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)
SPAN1_LAMBD Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
TIPK_LAMBD Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
TIPM_LAMBD Tail tip protein M
VLOM_LAMBD Outer membrane protein lom (ORF 206A)
TIPL_LAMBD Tail tip protein L
VXIS_LAMBD Excisionase
Y290_LAMBD Uncharacterized nin region protein ORF290
VRPO_LAMBD Replication protein O
VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)
Y64_LAMBD Putative uncharacterized protein ORF64
VKIL_LAMBD Protein kil
TMP_LAMBD Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry ...
TIPI_LAMBD Tail tip assembly protein I
TUBE_LAMBD Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)
BOR_LAMBD Lipoprotein bor

18 entries

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

Select_allDeselect_all
CAPSD_BPP21 Major capsid protein (Gene product 7) (Gene product E) (gpE) (Major head protein)
ENLYS_BPP21 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
NINE_BPP21 Protein ninE
DECO_BPP21 Head decoration protein (Head protein GPshp)
NING_BPP21 Protein ninG
PORTL_BPP21 Portal protein B (GpB) (Minor capsid protein B)
HOLIN_BPP21 Antiholin
NINF_BPP21 Protein ninF
TERS_BPP21 Terminase, small subunit (Gp1)
SPAN1_BPP21 Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
TERL_BPP21 Terminase, large subunit (DNA-packaging protein) (DNA-packaging protein gp2) (Gene product 2) (gp2) ...
SPAN2_BPP21 Spanin, outer lipoprotein subunit (o-spanin) (Lysis protein Rz1) (Outer membrane lipoprotein Rz1)
NINB_BPP21 Protein ninB
W_BPP21 Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining ...
YG78_BPP21 Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region
VINT_BPP21 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VXIS_BPP21 Excisionase
VG05_BPP21 Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5) [Cleaved into: Scaffold ...

8 entries

Enterobacteria phage H19B (Bacteriophage H19B)

Select_allDeselect_all
ENLYS_BPH19 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
REGQ_BPH19 Antitermination protein Q
NING_BPH19 Protein ninG
NINH_BPH19 Protein ninH
NINF_BPH19 Protein ninF
STXA_BPH19 Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verocytotoxin 1 ...
NINE_BPH19 Protein ninE
STXB_BPH19 Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) ...

7 entries

Enterobacteria phage 82 (Bacteriophage 82)

Select_allDeselect_all
REGQ_BP82 Antitermination protein Q
RUSA_BP82 Crossover junction endodeoxyribonuclease rusA (EC 3.1.21.10) (Holliday junction nuclease rusA) ...
NINE_BP82 Protein ninE
YLCG_BP82 Uncharacterized protein in rusA 3'region (ORF45)
YBCN_BP82 Uncharacterized protein in rusA 5'region (ORF151)
YLCH_BP82 Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)
YBCO_BP82 Putative nuclease ybcO (EC 3.1.-.-)

5 entries

Enterobacteria phage 434 (Bacteriophage 434)

Select_allDeselect_all
RCRO_BP434 Regulatory protein cro (Antirepressor)
RPC2_BP434 Regulatory protein CII
REXA_BP434 Protein rexA
VXIS_BP434 Excisionase
VINT_BP434 Integrase (EC 2.7.7.-) (EC 3.1.-.-)

2 entries

Corynephage beta

Select_allDeselect_all
DTX_CORBE Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...
DTXH_CORBE Diphtheria toxin homolog CRM228 [Cleaved into: Diphtheria toxin homolog CRM228 fragment A; ...

2 entries

Enterobacteria phage PA-2 (Bacteriophage PA-2)

Select_allDeselect_all
ENLYS_BPPA2 SAR-endolysin (EC 3.2.1.17) (Endolysin) (Lysis protein) (Lysozyme) (Muramidase)
PORI_BPPA2 Outer membrane porin protein LC

1 entry

Bacillus phage SP02 (Bacteriophage SP02)

DPOL_BPSP2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

1 entry

Bacillus phage SPR (Bacteriophage SPR)

MTBS_BPSPR Orphan methyltransferase M.SPRI (M.SPRI) (EC 2.1.1.37) (Cytosine-specific methyltransferase SPRI) ...

1 entry

Bacillus phage rho11s (Bacteriophage rho-11s)

MTBR_BPRH1 Orphan methyltransferase M.Rho11sI (M.Rho11sI) (EC 2.1.1.37) (Bsu P11s) (Cytosine-specific ...

1 entry

Corynephage omega

DTX_COROM Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC 2.4.2.36) [Cleaved into: ...