Teseptimavirus

VIRION

Non-enveloped, head-tail structure. Head is about 60 nm in diameter. The tail is non-contractile, has 6 short subterminal fibers. The capsid is icosahedral with a T=7 symmetry.

GENOME

image

Linear, dsDNA genome of about 40-42 kb encoding for about 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription of class I genes by host RNA polymerase before the viral genome completely exits out of capsid.
  4. Transcription of class II genes by T7 RNA polymerase.
  5. Bacterial genome degradation
  6. Replication of genomic DNA by T7 DNA polymerase, formation of viral genome concatemers.
  7. Transcription of class III genes by T7 RNA polymerase.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

57 entries grouped by protein (browse by keywords)

1 entry

Major capsid protein (Gene product 10A) (Gp10A) (Major head protein)

CAPSA_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Minor capsid protein (Gene product 10B) (Gp10B) (Minor head protein)

CAPSB_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Single-stranded DNA-binding protein gp2.5 (SSB protein)

DNBI_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

DNA ligase (EC 6.5.1.1) (DNA ligase gp1.3) (Gene product 1.3) (Gp1.3)

DNLI_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)

DPOL_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)

ENDO_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T7 endolysin)

ENLYS_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Peptidoglycan transglycosylase gp16 (EC 4.2.2.n1) (Internal core protein gp16)

EXLYS_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)

EXRN_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)

FIBER_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Gene 0.4 protein (Gene product 0.4) (Gp0.4)

GP04_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Inhibitor of dGTPase (Gene product 1.2) (Gp1.2) (Inhibitor of dGTPase gp1.2)

GP12_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Probable scaffold protein gp13 (Gene product 13) (Gp13)

GP13_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Internal virion protein gp14 (Gene product 14) (Gp14)

GP14_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Internal virion protein gp15 (Gene product 15) (Gp15)

GP15_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Probable RecBCD inhibitor gp5.9 (Gene product 5.9) (Gp5.9)

GP59_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 6.7 (Gene product 6.7) (Gp6.7)

GP67_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 7.3 (Gene product 7.3) (Gp7.3)

GP73_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Holin (Gene product 17.5) (Gp17.5)

HOLIN_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Inhibitor of toxin/antitoxin system (Gene product 4.5) (Gp4.5)

ITAS_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Nucleotide kinase gp1.7 (Gene product 1.7) (Gp1.7)

NUCK_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein Ocr (Gene product 0.3) (Gp0.3) (Overcome classical restriction) (Ocr)

OCR_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)

PK_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Portal protein (Gene product 8) (Gp8) (Head-to-tail connector)

PORTL_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)

PRIM_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)

RPOL_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Capsid assembly scaffolding protein (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold protein)

SCAF_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein suppressor of silencing (Gene product 5.5)

SGS_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)

SPAN1_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)

SPAN2_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Terminase, large subunit (DNA-packaging protein) (Gene product 19) (Gp19)

TERL_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Terminase, small subunit gp18 (DNA-packaging protein A) (Gene product 18) (Gp18)

TERS_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Tail tubular protein gp11 (Gene product 11) (Gp11)

TUBE1_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Tail tubular protein gp12 (Gene product 12) (Gp12)

TUBE2_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Fusion protein 5.5/5.7

V5557_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)

VRPI_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 0.5 (Gene product 0.5) (Gp0.5)

Y05_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 0.6B

Y06_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Uncharacterized protein 1.1 (Gene product 1.1) (Gp1.1)

Y11_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 1.4 (Gene product 1.4) (Gp1.4)

Y14_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 1.5 (Gene product 1.5) (Gp1.5)

Y15_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 1.6 (Gene product 1.6) (Gp1.6)

Y16_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 1.8 (Gene product 1.8) (Gp1.8)

Y18_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 19.2 (Gene product 19.2) (Gp19.2)

Y192_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 19.3 (Gene product 19.3) (Gp19.2)

Y193_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 19.5 (Gene product 19.5) (Gp19.5)

Y195_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 2.8 (Gene product 2.8) (Gp2.8)

Y28_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 3.8 (Gene product 3.8) (Gp3.8)

Y38_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.1 (Gene product 4.1) (Gp4.1)

Y41_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Preotein 4.2 (Gene product 4.2) (Gp4.2)

Y42_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.3 (Gene product 4.3) (Gp4.3)

Y43_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.7 (Gene product 4.7) (Gp4.7)

Y47_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 5.3 (Gene product 5.3) (Gp5.3)

Y53_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 6.3 (Gene product 6.3) (Gp6.3)

Y63_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 6.5 (Gene product 6.5) (Gp6.5)

Y65_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 7 (Gene product 7) (Gp7)

Y7_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 7.7 (Gene product 7.7) (Gp7.7)

Y77_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain