Schitoviridae (taxid:2842329)

VIRION

Non-enveloped, head-tail structure. The icosahedral capsid is about 70 nm in diameter, with a T=9 icosahedral symmetry . The virion contains about 4 copies of a viral RNA polymerase (vRNAP) .

GENOME

Linear, dsDNA genome of about 70 kb encoding 72 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

1. Adsorption: the phage attaches to the target cell through its tail fibers.
2. Ejection of the viral DNA and the viral RNA polymerase (vRNAP) into host cell cytoplasm .
3. Transcription by the vRNAP of the phage early genes.
4. Replication of genomic DNA. Transcription (by the host RNAP) and translation of late genes.
5. Assembly of an empty procapsid and packaging of the genome.
6. Viral tail fibers assembly and viral tail assembly.
7. Mature virions are released from the cell by lysis.