Straboviridae (taxid:2946170)
VIRION

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Non-enveloped, head-tail structure with Myo-type morphology. The prolate head is 120 nm in length and 86 nm in width. The tail is contractile, has 6 long terminal fibers, 6 short spikes and a small base plate. The capsid has an elongated icosahedral symmetry T=13 Q=21, composed of 152 capsomers .
GENOME
Linear, dsDNA genome of about 169 kb, encoding for approximately 300 proteins.
GENE EXPRESSION
Genes are transcribed by operons.
ENZYMES
- DNA-dependent DNA polymerase B [P04415]
- DNA topoisomerase [P09176]
- DNA primase [P04520]
- Serine protease (Peptidase S77) [P06807]
- ADP-ribosyltransferase [P39423, P39421]
- DNA ligase [P00970]
- RNA ligase [P32277]
- Exonuclease [P04521]
- Endonuclease [P04418, P07059, P39250]
- DNA adenine methylase [P04392]
- Terminase [P17312]
- NAD(+)--arginine ADP-ribosyltransferase [P12726]
- Deoxycytidylate deaminase [P16006]
- Polynucleotide kinase [P06855]
- Ribonucleoside-diphosphate reductase [P32282]
- Deoxynucleotide monophosphate kinase [P04531]
- Dihydrofolate reductase [P04382]
- Thymidylate synthase [P00471]
- Thymidine kinase [P13300]
- Ribonuclease H [P13319]
- Exodeoxyribonuclease [P04536]
- Endolysin [P09176]
REPLICATION
CYTOPLASMIC
- Adsorption: the phage attaches to the target cell through its tail fibers.
- Viral exolysin degrades cell wall locally
- Ejection of the viral DNA into host cell cytoplasm by contraction of the tail sheath.
- Transcription and translation of early genes.
- Replication of genomic DNA. Transcription and translation of late genes.
- Assembly of an empty procapsid and packaging of the genome.
- Viral tail fibers assembly and viral tail assembly.
- Mature virions are released from the cell by lysis.
Andrei Fokine, Paul R. Chipman, Petr G. Leiman, Vadim V. Mesyanzhinov, Venigalla B. Rao, Michael G. Rossmann
Proc. Natl. Acad. Sci. U.S.A. April 20, 2004; 101: 6003?6008
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)348 entries grouped by strain
269 entries
Enterobacteria phage T4 (Bacteriophage T4) reference strain
8 entries
Escherichia phage RB69 (Bacteriophage RB69) reference strain
1 entry
Enterobacteria phage T6 (Bacteriophage T6) reference strain
10 entries
Vibrio phage KVP40 (isolate Vibrio parahaemolyticus/Japan/Matsuzaki/1991) (KVP40) (Bacteriophage KVP40) reference strain
3 entries
Salmonella phage S16 (Salmonella phage vB_SenM-S16) reference strain
1 entry
Acinetobacter phage Ac42 (Acinetobacter phage 42) reference strain
1 entry
Erwinia phage FBB1 reference strain
1 entry
Escherichia phage RB16 reference strain
1 entry
Shigella phage SP18 reference strain
1 entry
Yersinia phage phiR1-RT reference strain
11 entries
Enterobacteria phage T2 (Bacteriophage T2)
3 entries
Escherichia phage RB69 (Bacteriophage RB69)
9 entries
Enterobacteria phage T6 (Bacteriophage T6)
5 entries
Enterobacteria phage K3 (Bacteriophage K3)
5 entries
Escherichia phage AR1 (Bacteriophage AR1)
3 entries
Enterobacteria phage LZ3 (Bacteriophage LZ3)
3 entries
Enterobacteria phage LZ5 (Bacteriophage LZ5)
2 entries
Enterobacteria phage LZ1 (Bacteriophage LZ1)
2 entries
Enterobacteria phage Ox2 (Bacteriophage Ox2)
2 entries
Enterobacteria phage RB18 (Bacteriophage RB18)
2 entries
Enterobacteria phage RB51 (Bacteriophage RB51)
1 entry
Enterobacteria phage LZ4 (Bacteriophage LZ4)
1 entry
Enterobacteria phage M1 (Bacteriophage M1)
1 entry
Enterobacteria phage RB3 (Bacteriophage RB3)
1 entry
Enterobacteria phage RB32 (Bacteriophage RB32)
1 entry