Jingmenvirus group (taxid:2982806)

VIRION

Enveloped, 30-35 nm in diameter. Each segment can be packaged separately, in a multicomponent viral system.

GENOME

Segmented linear ssRNA(+) genome with a total length of approximately 7.8 kb. The 5' RNA may be capped, as the virus encodes an MTase similar to a flavivirus.

GENE EXPRESSION

Virion RNAs are infectious and serve as both genomes and viral messenger RNAs.

ENZYMES

• RNA-dependent RNA polymerase [RdRp]
• FAD capping?]

REPLICATION

1. Attachement of the viral envelope protein E to host receptors mediates internalization into the host cell.
2. Fusion of virus membrane with host membrane. RNA genome is released into the cytoplasm.
3. The positive-sense genomic ssRNA are translated.
4. Replication takes place presumably in cytoplasmic viral factories. dsRNA segments are synthesized from the genomic ssRNA(+).
5. The dsRNA segments are transcribed/replicated thereby providing viral mRNAs and new ssRNA(+) genomes.
6. Virus assembly: The virion buds and exits the cell.