Phycodnaviridae (taxid:10501)
VIRION
Enveloped virion of which the membrane is surrounded by a capsid with an icosahedral symmetry (T=169), 100-220 nm in diameter. Dense material are present at each 5-fold symmetry vertex. Coccolithovirus have an outer membrane
GENOME
Linear, dsDNA genome of 100-560 kb with crosslinked hairpin ends. PBCV-1 genome encode for approximately 700 ORFs.
GENE EXPRESSION
ENZYMES
- DNA-directed DNA polymerase family B [A188aR]
- Cell-type capping
- Protease (Peptidase S74) [A540L]
- Protease (Peptidase G2) [Fr5L_185R]
- Intein (Peptidase N10) [DNA pol]
- Ribonucleoside-diphosphate reductase
REPLICATION
NUCLEO-CYTOPLASMIC
- Virus attaches to host receptors , inducing release of viral genome into the cell.
- Migration of the DNA core to the nucleus?
- The viral genome can enter latency by integrating in host chromosome.
- Synthesis of early proteins.
- Replication of genomic DNA.
- Late proteins synthesis, assembly of new virions in the cytoplasm
- Cell lysis and virion release in the extracellular space.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)44 entries grouped by protein
1 entry
Putative protein A464R
1 entry
Putative transposase A625R
4 entries
DNA polymerase (EC 2.7.7.7)
1 entry
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
1 entry
Exolysin (EC 4.2.2.-)
1 entry
Potassium channel protein kcv
1 entry
mRNA-capping enzyme (GTP--RNA guanylyltransferase) (mRNA guanylyltransferase) (EC 2.7.7.50)
3 entries
Major capsid protein (MCP)
2 entries
Type II methyltransferase M.CviBI (M.CviBI) (EC 2.1.1.72) (Adenine-specific methyltransferase CviBI) (Modification methylase CviBI)
1 entry
Type II methyltransferase M.CviAII (M.CviAII) (EC 2.1.1.72) (Adenine-specific methyltransferase CviAII) (Modification methylase CviAII)
1 entry
Modification methylase CviBIII (M.CviBIII) (EC 2.1.1.72) (Adenine-specific methyltransferase CviBIII) (Orphan methyltransferase M.CviBIII)
1 entry
Type II methyltransferase M.CvrRI (M.CviRI) (EC 2.1.1.72) (Adenine-specific methyltransferase CviRI) (Modification methylase CviRI)
1 entry
Minor capsid protein P10
1 entry
Minor capsid protein P11
1 entry
Minor capsid protein P12
1 entry
Minor capsid protein P13
1 entry
Minor capsid protein P14
1 entry
Minor capsid protein P2
1 entry
Minor capsid protein 3 (Minor capsid protein Vp20.5)
1 entry
Minor capsid protein P4
1 entry
Minor capsid protein P5
1 entry
Minor capsid protein P6 (Minor capsid protein Vp25)
1 entry
Minor capsid protein P7
1 entry
Minor capsid protein P8
1 entry
Minor capsid protein P9
1 entry
Probable DNA polymerase sliding clamp 1 (Proliferating cell nuclear antigen homolog 1) (PCNA 1)
1 entry
Probable DNA polymerase sliding clamp 2 (Proliferating cell nuclear antigen homolog 2) (PCNA 2)
1 entry
Penton capsid protein P1
1 entry
Superoxide dismutase
1 entry
Type II restriction enzyme CviJI (R.CviJI) (EC 3.1.21.4) (Endonuclease CviJI) (Type-2 restriction enzyme CviJI)
1 entry
Type II restriction enzyme CviAII (R.CviAII) (EC 3.1.21.4) (Endonuclease CviAII) (Type-2 restriction enzyme CviAII)
1 entry
Probable flavin-dependent thymidylate synthase (FDTS) (EC 2.1.1.148) (FAD-dependent thymidylate synthase)
1 entry
5'RNA triphosphatase A449R (EC 3.6.1.74)
1 entry
Viral polyamine acetyltransferase (vPAT) (EC 2.3.1.57)
1 entry
Uncharacterized protein A284L
1 entry
Putative ABC transporter A445L
1 entry
Putative transcription factor A494R
1 entry