Eukaryotic host translation shutoff by virus

The majority of cellular mRNAs initiate translation! through the recruitment of a multisubunit translation initiation complex termed eIF4F, which consists of the cap-binding protein eIF4E, the RNA helicase eIF4A, and the adaptor protein eIF4G. eIF4G binds poly(A)-binding protein (PABP) to mediate 5' -> 3' communication, probably to promote efficient translation of intact correctly processed mRNAs. eIF4E binding protein 1 (eIF4E-BP1) functions as a translational repressor that limits eIF4E availability and therefore eIF4F complex formation.


Viruses have evolved ways of interacting with the host translational machinery to shutoff host gene expression. This global inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response .
All the viruses inducing the shutoff of translation are able to continue to translate at least part of their mRNAs using non-canonical translation: IRES, Ribosome shunting, or VPG initiation. For adenoviridae, polyomaviridae and togaviridae the cellular translation shutoff takes place at the late phase of infection and ensures an optimal production of viral structural proteins.
Under stress conditions such as viral infection some cellular translation can continue when the cap-dependent translation initiation is inhibited. Expression of specific cellular proteins seems to occur through cap-independent mechanisms .

Viruses inducing host translation shutoff:

Family Virus Viral protein Shutoff strategy Viral translation ref.
Adenoviridae Adenovirus Shutoff protein 100K Inhibits eIF4G-Mnk1 and prevents EIF4E phosphorylation Ribosome shunting on late mRNAs
Bunyaviridae Bunyamwera virus Nucleoprotein Nuclear retention of PABP Viral mRNAs non polyadenylated
Caliciviridae Norovirus
Feline calicivirus
Protease 3C
Protease
PABP cleavage VPg
Feline calicivirus Protease Cleavage of eIF4G1 and eIF4G2 VPg
Dicistroviridae Cripavirus ? Dissociation of eIF4G and eIF4E IRES
Orthomyxoviridae Influenza virus ? Dephosphorylation of of eIF-4E eIF-4E independent translation of viral mRNAs
Picornaviridae Poliovirus Protease 2A Cleavage of eIF4GI and eIF4GII IRES
Protease 3C Cleavage of eIF5B IRES
Protease 3C PABP cleavage IRES
Rhinovirus Protease 2A Cleavage of eIF4GI and eIF4GII IRES
Coxsackie virus Protease 2A Cleavage of eIF4GI and eIF4GII IRES
Coxsackie virus Protease 2A,3C PABP cleavage IRES
Protease 3C Cleavage of eIF5B IRES
Encephalomyocarditis virus Protein 2A ? IRES
? Dephosphorylation of 4E-BP1 IRES
Foot-and-mouth disease virus Leader protease Cleavage of eIF4GI and eIF4GII IRES
Protease 3C Cleavage of PABP, eIF3a, eIF3b, and eIF4A IRES
Polyomaviridae SV40 Small T antigen Dephosphorylation of 4E-BP1 IRES
Reoviridae Rotavirus NSP3 Interacts with EIF4G and evicts PABP from initiation complexes. Nuclear relocalization of PABP NSP3 replaces PABP and bind the non polyAdenylated viral mRNAs
Rhabdoviridae Vesicular stomatitis virus ? Dephosphorylation of 4E-BP1 classical
Retroviridae HIV-1 Protease Cleavage of eIF4GI and PABP IRES
HTLV-1 Protease Cleavage of eIF4GI IRES
Moloney murine leukemia virus Protease Cleavage of eIF4GI and eIF4GII IRES
Togaviridae Rubella virus Capsid protein PABP sequestration classical
Sindbis virus dsRNA leading to PKR-mediated inhibition of eIF2alpha DLP
Coronaviridae SARS-CoV Nsp1 Binding to host 40S subunit Viral mRNA protected by 5'-end leader sequence
Bat-CoV Nsp1
TGEV Nsp1
Links Uniprot Keyword: KW-1193
GO ontology: GO:0039604

Matching UniProtKB/Swiss-Prot entries

196 entries grouped by strain (browse by keywords)

2 entries

Bat coronavirus HKU3 (BtCoV) (SARS-like coronavirus HKU3) reference strain

Select_allDeselect_all
R1AB_BCHK3 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_BCHK3 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Bat coronavirus HKU4 (BtCoV) (BtCoV/HKU4/2004) reference strain

Select_allDeselect_all
R1A_BCHK4 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_BCHK4 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bat coronavirus HKU9 (BtCoV) (BtCoV/HKU9) reference strain

Select_allDeselect_all
R1A_BCHK9 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_BCHK9 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Human SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus) reference strain

Select_allDeselect_all
R1A_CVHSA Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVHSA Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) reference strain

Select_allDeselect_all
PRO_HTL1C Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...
POL_HTL1C Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...

2 entries

Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) reference strain

Select_allDeselect_all
POL_HTL1A Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...
PRO_HTL1A Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...

2 entries

Human T-cell leukemia virus 2 (HTLV-2) reference strain

Select_allDeselect_all
POL_HTLV2 Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...
PRO_HTLV2 Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...

2 entries

Human T-cell leukemia virus 3 (strain 2026ND) (HTLV-3) reference strain

Select_allDeselect_all
PRO_HTL32 Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...
POL_HTL32 Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...

2 entries

Human T-cell leukemia virus 3 (strain Pyl43) (HTLV-3) reference strain

Select_allDeselect_all
POL_HTL3P Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...
PRO_HTL3P Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...

2 entries

Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) reference strain

Select_allDeselect_all
R1A_CVHN5 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVHN5 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Murine coronavirus (strain A59) (MHV-A59) (Murine hepatitis virus) reference strain

Select_allDeselect_all
R1AB_CVMA5 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_CVMA5 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Aichi virus (strain Human/A846/88/1989) (AiV) (Aichi virus (strain A846/88)) reference strain

POLG_AIVA8 Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0; Capsid protein VP3 (P1C) ...

1 entry

Bat coronavirus HKU5 (BtCoV) (BtCoV/HKU5/2004) reference strain

R1AB_BCHK5 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

1 entry

Bunyamwera virus (BUNV) reference strain

NCAP_BUNYW Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Bunyavirus La Crosse reference strain

NCAP_BUNLC Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Bunyavirus La Crosse (isolate Human/United States/L78/1978) reference strain

NCAP_BUNL8 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Encephalomyocarditis virus (strain Rueckert) (EMCV) reference strain

POLG_EMCVR Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV) reference strain

POLG_FCVUR Genome polyprotein [Cleaved into: Protein p5.6; Protein p32; NTPase (EC 3.6.1.15) (p39); Protein ...

1 entry

Fowl adenovirus A serotype 1 (strain CELO / Phelps) (FAdV-1) (Avian adenovirus gal1 (strain Phelps)) reference strain

SHUT_ADEG1 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12) reference strain

SHUT_ADE12 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) reference strain

SHUT_ADE02 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human adenovirus F serotype 40 (HAdV-40) (Human adenovirus 40) reference strain

SHUT_ADE40 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain

POL_HV1MA Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain

POL_HV1A2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain

POL_HV1B1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

pdb 1A9M; 1AJV; 1AJX; 1AXA; 1BQM; 1BQN; 1D4H; 1D4I; 1D4J; 1DLO; 1DW6; 1EBK; 1EBW; 1EBY; 1EBZ; 1EC0; 1EC1; 1EC2; 1EC3; 1EET; 1G35; 1GNM; 1GNN; 1GNO; 1HAR; 1HBV; 1HEF; 1HEG; 1HIH; 1HMV; 1HNI; 1HNV; 1HOS; 1HPS; 1HPZ; 1HQE; 1HQU; 1HRH; 1HTE; 1HTF; 1HTG; 1HVI; 1HVK; 1HVP; 1HVU; 1HYS; 1IKV; 1IKW; 1IKX; 1IKY; 1J5O; 1KJH; 1MER; 1MES; 1MET; 1MEU; 1N5Y; 1N6Q; 1NPA; 1NPV; 1NPW; 1QE1; 1QMC; 1R0A; 1RDH; 1RTD; 1RVL; 1RVM; 1RVN; 1RVO; 1RVP; 1RVQ; 1RVR; 1S6P; 1S6Q; 1S9E; 1S9G; 1SBG; 1SUQ; 1SV5; 1T03; 1T05; 1T7K; 1TV6; 1TVR; 1UWB; 1W5V; 1W5W; 1W5X; 1W5Y; 1YT9; 1ZP8; 1ZPA; 1ZSF; 1ZSR; 2AQU; 2B5J; 2B6A; 2BAN; 2BBB; 2BE2; 2EXF; 2G69; 2HB3; 2HMI; 2HNZ; 2HS1; 2HS2; 2I4D; 2I4U; 2I4V; 2I4W; 2I4X; 2I5J; 2IAJ; 2IC3; 2IDW; 2IEO; 2JZW; 2L45; 2L46; 2L4L; 2UXZ; 2UY0; 2VG5; 2VG6; 2VG7; 2X4U; 2YKM; 2YKN; 2ZD1; 2ZE2; 3AVI; 3BGR; 3DLK; 3GGA; 3GGV; 3GGX; 3HVT; 3IG1; 3IRX; 3IS9; 3ISN; 3ITH; 3JSM; 3JYT; 3K2P; 3K4V; 3KLE; 3KLF; 3KLG; 3KLH; 3KLI; 3NDT; 3NU3; 3NU4; 3NU5; 3NU6; 3NU9; 3NUJ; 3NUO; 3OK9; 3PSU; 3QAA; 3QLH; 3QO9; 3TKG; 3TKW; 3TL9; 3TLH; 3V4I; 3V6D; 3V81; 3ZPS; 3ZPT; 3ZPU; 4COE; 4CP7; 4CPQ; 4CPR; 4CPS; 4CPT; 4CPU; 4CPW; 4CPX; 4DG1; 4G1Q; 4G8G; 4G8I; 4G9D; 4G9F; 4H4M; 4H4O; 4I2P; 4I2Q; 4ICL; 4ID5; 4IDK; 4IFV; 4IFY; 4IG0; 4IG3; 4KFB; 4KKO; 4KO0; 4LSL; 4LSN; 4MFB; 4O44; 4O4G; 4OJR; 4PQU; 4PUO; 4PWD; 4Q0B; 4QAG; 4R5P; 4RW4; 4RW6; 4RW7; 4RW8; 4RW9; 4U8W; 4WE1; 4YE3; 4YHQ; 4ZIP; 4ZLS; 5AGZ; 5AH6; 5AH7; 5AH8; 5AH9; 5AHA; 5AHB; 5AHC; 5BRY; 5BS4; 5C24; 5C25; 5C42; 5CYM; 5CYQ; 5D3G; 5FDL; 5HBM; 5HLF; 5HP1; 5HRO; 5I3U; 5I42; 5J1E; 5JFP; 5JFU; 5JG1; 5OI2; 5OI3; 5OI5; 5OI8; 5OIA; 5T6Z; 5T70; 5TEP; 5TER; 5TUQ; 5TW3; 5TXL; 5TXM; 5TXN; 5TXO; 5TXP; 5UFZ; 5ULT; 5UOV; 5UPZ; 5UV5; 5V5L; 5V5M; 5VQQ; 5VQR; 5VQS; 5VQT; 5VQU; 5VQV; 5VQW; 5VQX; 5VQY; 5VQZ; 5W5W; 5YOJ; 6AMO; 6AN2; 6AN8; 6ANQ; 6AOC; 6ASW; 6AVM; 6AVT; 6B19; 6BZ2; 6C0J; 6C0K; 6C0L; 6C0N; 6C0O; 6C0P; 6C0R; 6C8X; 6C8Y; 6CGF; 6D0D; 6D0E; 6DTW; 6DTX; 6DUF; 6DUG; 6DUH; 6ECL; 6ELI; 6HAK; 6O9E; 6OE3; 6OUN; 6PRF

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain

POL_HV1BR Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain

POL_HV1H2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain

POL_HV1JR Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain

POL_HV1MN Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1) reference strain

POL_HV1RH Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1) reference strain

POL_HV1Y2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1) reference strain

POL_HV1B9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain

POL_HV1ET Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain

POL_HV1EL Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain

POL_HV190 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1) reference strain

POL_HV1YB Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain

POL_HV1YF Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain

POL_HV1AN Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate BEN) (HIV-2) reference strain

POL_HV2BE Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate Ghana-1) (HIV-2) reference strain

POL_HV2G1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2) reference strain

POL_HV2RO Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate ST) (HIV-2) reference strain

POL_HV2ST Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human rhinovirus A serotype 89 (strain 41467-Gallo) (HRV-89) reference strain

POLG_HRV8A Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Moloney murine leukemia virus (isolate Shinnick) (MoMLV) reference strain

POL_MLVMS Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15 (MA); RNA-binding ...

1 entry

Poliovirus type 1 (strain Mahoney) reference strain

POLG_POL1M Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Porcine adenovirus A serotype 3 (PAdV-3) (Porcine adenovirus 3) reference strain

SHUT_ADEP3 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Salivirus A (isolate Human/Nigeria/NG-J1/2007) (SV-A) reference strain

POLG_SALVA Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0; Capsid protein VP3 (P1C) ...

1 entry

Simian immunodeficiency virus (isolate CPZ GAB1) (SIV-cpz) (Chimpanzee immunodeficiency virus) reference strain

POL_SIVCZ Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate EK505) (SIV-cpz) (Chimpanzee immunodeficiency virus) reference strain

POL_SIVEK Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate MB66) (SIV-cpz) (Chimpanzee immunodeficiency virus) reference strain

POL_SIVMB Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate PBj14/BCL-3) (SIV-sm) (Simian immunodeficiency virus sooty mangabey monkey) reference strain

POL_SIVSP Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate TAN1) (SIV-cpz) (Chimpanzee immunodeficiency virus) reference strain

POL_SIVTN Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian virus 40 (SV40) reference strain

ST_SV40 Small t antigen (ST) (ST-AG)

1 entry

Snake adenovirus serotype 1 (SnAdV-1) reference strain

SHUT_ADES1 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

169_VACCW Protein 169

2 entries

Bat coronavirus 133/2005 (BtCoV) (BtCoV/133/2005)

Select_allDeselect_all
R1AB_BC133 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_BC133 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Bat coronavirus 279/2005 (BtCoV) (BtCoV/279/2005)

Select_allDeselect_all
R1A_BC279 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_BC279 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bat coronavirus Rp3/2004 (BtCoV/Rp3/2004) (SARS-like coronavirus Rp3)

Select_allDeselect_all
R1A_BCRP3 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_BCRP3 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bovine coronavirus (strain 98TXSF-110-ENT) (BCoV-ENT) (BCV)

Select_allDeselect_all
R1A_CVBEN Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVBEN Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bovine coronavirus (strain 98TXSF-110-LUN) (BCoV-LUN) (BCV)

Select_allDeselect_all
R1A_CVBLU Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVBLU Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bovine coronavirus (strain Mebus) (BCoV) (BCV)

Select_allDeselect_all
R1A_CVBM Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVBM Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Bovine coronavirus (strain Quebec) (BCoV) (BCV)

Select_allDeselect_all
R1AB_CVBQ Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_CVBQ Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Human T-cell leukemia virus 1 (isolate Melanesia mel5 subtype C) (HTLV-1)

Select_allDeselect_all
PRO_HTL1L Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); ...
POL_HTL1L Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein ...

2 entries

Human coronavirus HKU1 (isolate N1) (HCoV-HKU1)

Select_allDeselect_all
R1A_CVHN1 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVHN1 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Human coronavirus HKU1 (isolate N2) (HCoV-HKU1)

Select_allDeselect_all
R1AB_CVHN2 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_CVHN2 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Human coronavirus OC43 (HCoV-OC43)

Select_allDeselect_all
R1A_CVHOC Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVHOC Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1) (Human coronavirus EMC)

Select_allDeselect_all
R1AB_CVEMC Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...
R1A_CVEMC Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 ...

2 entries

Murine coronavirus (strain 2) (MHV-2) (Murine hepatitis virus)

Select_allDeselect_all
R1A_CVM2 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVM2 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

2 entries

Murine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus)

Select_allDeselect_all
R1A_CVMJH Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVMJH Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

1 entry

AKV murine leukemia virus (AKR (endogenous) murine leukemia virus)

POL_MLVAV Gag-Pol polyprotein [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); ...

1 entry

Bovine enterovirus (strain VG-5-27) (BEV)

POLG_BOVEV Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Bunyavirus germiston

NCAP_BUNGE Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Bunyavirus snowshoe hare

NCAP_BUNSH Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Canine adenovirus serotype 1 (strain CLL) (CAdV-1) (Canine adenovirus 1 (strain CLL))

SHUT_ADECC Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Canine adenovirus serotype 1 (strain RI261) (CAdV-1) (Canine adenovirus 1 (strain RI261))

SHUT_ADECR Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Cas-Br-E murine leukemia virus

POL_MLVCB Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15; RNA-binding phosphoprotein p12 ...

1 entry

Coxsackievirus A16 (strain G-10)

POLG_CX16G Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus A16 (strain Tainan/5079/98)

POLG_CX16T Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus A21 (strain Coe)

POLG_CXA21 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus A24 (strain EH24/70)

POLG_CXA24 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus A9 (strain Griggs)

POLG_CXA9 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B1 (strain Japan)

POLG_CXB1J Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid ...

1 entry

Coxsackievirus B2 (strain Ohio-1)

POLG_CXB2O Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B3 (strain Nancy)

POLG_CXB3N Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B3 (strain Woodruff)

POLG_CXB3W Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B4 (strain E2)

POLG_CXB4E Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B4 (strain JVB / Benschoten / New York/51)

POLG_CXB4J Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B5 (strain Peterborough / 1954/UK/85)

POLG_CXB5P Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Coxsackievirus B6 (strain Schmitt)

POLG_CXB6S Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 1 (strain Human/Egypt/Farouk/1951) (E-1)

POLG_EC01F Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 11 (strain Gregory)

POLG_EC11G Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 12 (strain Travis)

POLG_EC12T Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 30 (strain Bastianni)

POLG_EC30B Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 5 (strain Noyce)

POLG_EC05N Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 6 (strain Charles)

POLG_EC06C Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 9 (strain Barty)

POLG_EC09B Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Echovirus 9 (strain Hill)

POLG_EC09H Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Encephalomyocarditis virus

POLG_EMCV Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Encephalomyocarditis virus (strain emc-b nondiabetogenic)

POLG_EMCVB Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Encephalomyocarditis virus (strain emc-d diabetogenic)

POLG_EMCVD Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Feline calicivirus (strain CFI/68 FIV) (FCV)

POLG_FCVC6 Genome polyprotein [Cleaved into: Protein p5.6; Protein p32; NTPase (EC 3.6.1.15) (p39); Protein ...

1 entry

Feline calicivirus (strain F9) (FCV)

POLG_FCVF9 Genome polyprotein [Cleaved into: Protein p5.6; Protein p32; NTPase (EC 3.6.1.15) (p39); Protein ...

1 entry

Feline calicivirus (strain Japanese F4) (FCV)

POLG_FCVF4 Genome polyprotein [Cleaved into: Protein p5.6; Protein p32; NTPase (EC 3.6.1.15) (p39); Protein ...

1 entry

Fowl adenovirus C serotype 10 (strain SA2) (FAdV-10) (Fowl adenovirus 10)

SHUT_ADEGX Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Friend murine leukemia virus (isolate 57) (FrMLV)

POL_MLVF5 Gag-Pol polyprotein [Cleaved into: Matrix protein p15; RNA-binding phosphoprotein p12 (pp12); Capsid ...

1 entry

Friend murine leukemia virus (isolate FB29) (FrMLV)

POL_MLVFF Gag-Pol polyprotein [Cleaved into: Matrix protein p15; RNA-binding phosphoprotein p12 (pp12); Capsid ...

1 entry

Friend murine leukemia virus (isolate PVC-211) (FrMLV)

POL_MLVFP Gag-Pol polyprotein [Cleaved into: Matrix protein p15; RNA-binding phosphoprotein p12 (pp12); Capsid ...

1 entry

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

SHUT_ADE05 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human adenovirus F serotype 41 (HAdV-41) (Human adenovirus 41)

SHUT_ADE41 Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)

1 entry

Human enterovirus 70 (strain J670/71) (EV70) (EV-70)

POLG_HE701 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus 71 (EV71) (EV-71)

POLG_HE71 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus 71 (strain 7423/MS/87) (EV71) (EV-71)

POLG_HE71M Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus 71 (strain USA/BrCr/1970) (EV71) (EV-71)

POLG_HE71B Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human enterovirus D68 (EV68) (EV-68)

POLG_HED68 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)

POL_HV1U4 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)

POL_HV1B5 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)

POL_HV1LW Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)

POL_HV1N5 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)

POL_HV1OY Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)

POL_HV192 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)

POL_HV1ND Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)

POL_HV1Z2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)

POL_HV193 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)

POL_HV1VI Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)

POL_HV1MP Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)

POL_HV1M2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)

POL_HV19N Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)

POL_HV1SE Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)

POL_HV1V9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)

POL_HV1S9 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)

POL_HV1S2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)

POL_HV196 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)

POL_HV197 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)

POL_HV1MV Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate CAM2) (HIV-2)

POL_HV2CA Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate D194) (HIV-2)

POL_HV2D1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate KR) (HIV-2)

POL_HV2KR Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate NIH-Z) (HIV-2)

POL_HV2NZ Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2)

POL_HV2SB Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype B (isolate D205) (HIV-2)

POL_HV2D2 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype B (isolate EHO) (HIV-2)

POL_HV2EH Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human immunodeficiency virus type 2 subtype B (isolate UC1) (HIV-2)

POL_HV2UC Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Human klassevirus 1 (HKV-1)

POLG_HKV1 Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0; Capsid protein VP3 (P1C) ...

1 entry

Human rhinovirus 14 (HRV-14)

POLG_HRV14 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human rhinovirus 16 (HRV-16)

POLG_HRV16 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human rhinovirus 1A (HRV-1A)

POLG_HRV1A Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human rhinovirus 1B (HRV-1B)

POLG_HRV1B Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human rhinovirus 2 (HRV-2)

POLG_HRV2 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Human rhinovirus 3 (HRV-3)

POLG_HRV3 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Mengo encephalomyocarditis virus

POLG_ENMGO Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Murine leukemia virus (strain BM5 eco)

POL_MLVBM Gag-pol polyprotein [Cleaved into: Matrix protein p15; RNA-binding phosphoprotein p12 (pp12); Capsid ...

1 entry

Poliovirus type 1 (strain Sabin)

POLG_POL1S Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 2 (strain Lansing)

POLG_POL2L Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 2 (strain W-2)

POLG_POL2W Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Poliovirus type 3 (strain 23127)

POLG_POL32 Genome polyprotein [Cleaved into: P3; Protein 3AB; P1; Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Poliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)

POLG_POL3L Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Porcine enterovirus 9 (strain UKG/410/73)

POLG_PEV9U Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Radiation murine leukemia virus

POL_MLVRD Gag-Pol polyprotein [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); ...

1 entry

Simian immunodeficiency virus (isolate F236/smH4) (SIV-sm) (Simian immunodeficiency virus sooty mangabey monkey)

POL_SIVS4 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate GB1) (SIV-mnd) (Simian immunodeficiency virus mandrill)

POL_SIVGB Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate K6W) (SIV-mac) (Simian immunodeficiency virus rhesus monkey)

POL_SIVMK Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus (isolate Mm142-83) (SIV-mac) (Simian immunodeficiency virus rhesus monkey)

POL_SIVM1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus agm.grivet (isolate AGM gr-1) (SIV-agm.gri) (Simian immunodeficiency virus African green monkey grivet)

POL_SIVG1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus agm.vervet (isolate AGM TYO-1) (SIV-agm.ver) (Simian immunodeficiency virus African green monkey vervet)

POL_SIVVT Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus agm.vervet (isolate AGM155) (SIV-agm.ver) (Simian immunodeficiency virus African green monkey vervet)

POL_SIVV1 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Simian immunodeficiency virus agm.vervet (isolate AGM3) (SIV-agm.ver) (Simian immunodeficiency virus African green monkey vervet)

POL_SIVVG Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); ...

1 entry

Swine vesicular disease virus (strain H/3 '76) (SVDV)

POLG_SVDVH Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Swine vesicular disease virus (strain UKG/27/72) (SVDV)

POLG_SVDVU Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

1 entry

Theiler's murine encephalomyelitis virus (strain BeAn 8386) (TMEV)

POLG_TMEVB Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Theiler's murine encephalomyelitis virus (strain DA) (TMEV)

POLG_TMEVD Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Theiler's murine encephalomyelitis virus (strain GDVII) (TMEV)

POLG_TMEVG Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...