Varicellovirus

VIRION

Enveloped, spherical to pleomorphic, 150-200 nm in diameter, T=16 icosahedral symmetry. Capsid consists of 162 capsomers and is surrounded by an amorphous tegument. Glycoproteins complexes are embedded in the lipid envelope.

GENOME

Monopartite, linear, dsDNA genome of about 125 kb. The genome contains terminal and internal reiterated sequences.

GENE EXPRESSION

Each viral transcript usually encodes a single protein and has a promoter/regulatory sequence, a TATA box, a transcription initiation site, a 5' leader sequence of 30-300 bp (not translated), a 3' non-translated sequence of 10-30 bp, and a poly A signal. There are many gene overlaps. There are only few spliced genes. Some of the expressed ORFs are antisense to each other. Some ORFs can be accessed from more than one promoter.

Transcription occurs in three steps: immediate-early, early and late. The immediate-early genes are transcribed immediately after infection and ensure the transcription of early genes, which encode the proteins necessary for the viral replication. The late genes mostly encode structural proteins.

REPLICATION

NUCLEAR

Lytic replication:

  1. Attachment of the viral glycoproteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the core and the tegument proteins into the host cytoplasm.
  3. The capsid is transported to the nuclear pore where the viral DNA is released into the nucleus.
  4. Transcription of immediate early genes which promote transcription of early genes and protect the virus against innate host immunity.
  5. Transcription of early viral mRNA by host polymerase II, encoding proteins involved in replication of the viral DNA.
  6. A first round of circular genome amplification occurs by bidirectional replication
  7. Synthesis of linear concatemer copies of viral DNA by rolling circle.
  8. Transcription of late mRNAs by host polymerase II, encoding structural proteins.
  9. Assembly of the virus in nuclear viral factories and budding through the inner lamella of the nuclear membrane which has been modified by the insertion of herpes glycoproteins, throughout the Golgi and final release at the plasma membrane.

Latent replication : replication of circular viral episome in tandem with the host cell DNA using the host cell replication machinery.

Host-virus interaction

Innate immune response inhibition

Varicella virus inhibits the cascade leading to production of interferon-beta by targeting host IRF3 protein. Several viral proteins including ORF61, ORF47 and IE62 prevent IRF3 activation and subsequent induction of IFN-beta expression .

Adaptive immune response inhibition

Infected cells show a decrease in MHC class I peptide presentation at the cell surface. Although the mechanism is not fully understood, the ORF66 participates in this process .

Autophagy modulation

Varicella virus does not seem to modulate autophagy that occur in infected cells .

Host shut-off

Varicella-zoster virus IE63 protein represses the basal transcription machinery by disorganizing the pre-initiation complex.

Cell-cycle modulation

The HHV-1 UL24 homolog may inhibit the host cell cycle at the G2/M transition since UL24 from alpha-, beta-, and gammaherpesvirus all inhibit host cell cycle through inactivation of the cyclinB/cdc2 complex .

Apoptosis modulation

The viral protein ORF12 protein triggers phosphorylation of host ERK1/2 and inhibits apoptosis. In neurons, ORF63 also participates in the inhibition of apoptosis .

Host splicing inhibition

VZV IE4 is an alternative splicing regulator of host mRNA. It may act by binding with SR proteins .

Matching UniProtKB/Swiss-Prot entries

365 entries grouped by strain (browse by keywords)

All proteins are shown (view only 240 complete proteome entries)

75 entries

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

Select_allDeselect_all
GB_EHV1B Envelope glycoprotein B (gB)
GD_EHV1B Envelope glycoprotein D (gD) (Glycoprotein 17/18)
GP2_EHV1B Glycoprotein gp2 (Glycoprotein X) (GpX)
CEP3_EHV1B Cytoplasmic envelopment protein 3
LTP_EHV1B Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
GC_EHV1B Envelope glycoprotein C (gC) (Glycoprotein 13)
VG67_EHV1B Uncharacterized gene 67 protein (IR6 protein)
VG34_EHV1B Gene 34 protein
GK_EHV1B Envelope glycoprotein K (Syncytial protein)
GH_EHV1B Envelope glycoprotein H (gH)
GN_EHV1B Envelope glycoprotein N
CEP1_EHV1B Cytoplasmic envelopment protein 1
ICP22_EHV1B Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
CVC2_EHV1B Capsid vertex component 2
MCP_EHV1B Major capsid protein (MCP)
CEP2_EHV1B Cytoplasmic envelopment protein 2
GE_EHV1B Envelope glycoprotein E (gE)
ICP27_EHV1B mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
DPOL_EHV1B DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
EV45_EHV1B Envelope protein UL45 homolog
KITH_EHV1B Thymidine kinase (EC 2.7.1.21)
MB43_EHV1B Membrane protein UL43 homolog (Membrane protein ORF17)
CVC1_EHV1B Capsid vertex component 1
PAP_EHV1B DNA polymerase processivity factor (DNA-binding gene 18 protein) (Polymerase accessory protein) ...
DNBI_EHV1B Major DNA-binding protein
NEC2_EHV1B Nuclear egress protein 2
NP04_EHV1B Nuclear protein UL4 homolog
GL_EHV1B Envelope glycoprotein L (gL)
NEC1_EHV1B Nuclear egress protein 1
ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ICP0)
NP03_EHV1B Nuclear phosphoprotein UL3 homolog (ORF60 protein)
ITP_EHV1B Inner tegument protein
PRIM_EHV1B DNA primase (EC 2.7.7.-)
HELI_EHV1B DNA replication helicase (EC 3.6.4.-)
ICP4_EHV1B Major viral transcription factor (155 kDa immediate-early protein)
SCAF_EHV1B Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural gene ...
TEG5_EHV1B Tegument protein UL47 homolog (GP10)
HEPA_EHV1B DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
RIR1_EHV1B Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
VG02_EHV1B Uncharacterized gene 2 protein
SCP_EHV1B Small capsomere-interacting protein
VG01_EHV1B Uncharacterized gene 1 protein
VG75_EHV1B Uncharacterized gene 75 protein
UL20_EHV1B Protein UL20 homolog
TRM3_EHV1B Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TRX2_EHV1B Triplex capsid protein 2
TEG3_EHV1B Tegument protein UL14 homolog
US10_EHV1B Virion protein US10 homolog (Gene 66 protein)
PORTL_EHV1B Portal protein
RIR2_EHV1B Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
OBP_EHV1B Replication origin-binding protein (OriBP) (OBP)
VG59_EHV1B Uncharacterized gene 59 protein
US9_EHV1B Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
UL13_EHV1B Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
VG03_EHV1B Gene 3 protein
UL24_EHV1B Protein UL24 homolog
TRM1_EHV1B Tripartite terminase subunit 1
TEG1_EHV1B Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
VP22_EHV1B Tegument protein VP22 (Gene 11 protein)
VP16_EHV1B Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
TRM2_EHV1B Tripartite terminase subunit 2
TEG4_EHV1B Tegument protein UL21 homolog
UL32_EHV1B Packaging protein UL32 homolog
UNG_EHV1B Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TRX1_EHV1B Triplex capsid protein 1
US02_EHV1B Gene 68 protein
US03_EHV1B Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
SHUT_EHV1B Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG6_EHV1B Tegument protein UL55 homolog
TEG7_EHV1B Tegument protein UL51 homolog
GG_EHV1B Envelope glycoprotein G (gG)
GI_EHV1B Envelope glycoprotein I
AN_EHV1B Alkaline nuclease (EC 3.1.-.-)
GM_EHV1B Envelope glycoprotein M (gM)
DUT_EHV1B Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)

69 entries

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

Select_allDeselect_all
GC_VZVD Envelope glycoprotein C (gC) (Glycoprotein V) (gpV)
US9_VZVD Envelope protein US9 (Envelope protein 65) (ORF65 protein)
VP16_VZVD Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
CEP1_VZVD Cytoplasmic envelopment protein 1
HELI_VZVD DNA replication helicase (EC 3.6.4.-)
HEPA_VZVD DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
CEP3_VZVD Cytoplasmic envelopment protein 3
GK_VZVD Envelope glycoprotein K (Syncytial protein)
GL_VZVD Envelope glycoprotein L (gL)
CVC2_VZVD Capsid vertex component 2
DNBI_VZVD Major DNA-binding protein
CVC1_VZVD Capsid vertex component 1
ORF1_VZVD Structural protein 1 (Structural ORF1 protein)
ICP4_VZVD Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
MCP_VZVD Major capsid protein (MCP)
KITH_VZVD Thymidine kinase (EC 2.7.1.21)
ICP22_VZVD Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
ICP27_VZVD mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4) (Transcriptional transactivator ...
PRIM_VZVD DNA primase (EC 2.7.7.-)
ORF2_VZVD Membrane protein 2 (Membrane ORF2 protein)
GH_VZVD Envelope glycoprotein H (gH)
GN_VZVD Envelope glycoprotein N
CEP2_VZVD Cytoplasmic envelopment protein 2
MB43_VZVD Membrane protein UL43 homolog (Membrane protein ORF15)
PAP_VZVD DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
GE_VZVD Envelope glycoprotein E (gE)
LTP_VZVD Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
IE61_VZVD E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61) (RING-type E3 ...
NP04_VZVD Nuclear protein UL4 homolog (ORF56 protein)
PORTL_VZVD Portal protein
AN_VZVD Alkaline nuclease (EC 3.1.-.-)
ITP_VZVD Inner tegument protein
DUT_VZVD Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GI_VZVD Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
ORF0_VZVD Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)
ORF32_VZVD Phosphoprotein 32 (ORF32 Phosphoprotein)
NP03_VZVD Nuclear phosphoprotein UL3 homolog (ORF58 protein)
TRM3_VZVD Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit) [Cleaved into: Gene 42 ...
TRM1_VZVD Tripartite terminase subunit 1
RIR1_VZVD Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TRM2_VZVD Tripartite terminase subunit 2
TEG4_VZVD Tegument protein UL21 homolog
TEG3_VZVD Tegument protein UL14 homolog
UL24_VZVD Protein UL24 homolog
UL20_VZVD Protein UL20 homolog (Gene 39 membrane protein)
TRX1_VZVD Triplex capsid protein 1
ORF57_VZVD Uncharacterized protein 57 (Uncharacterized ORF57 protein)
TEG1_VZVD Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
SHUT_VZVD Virion host shutoff protein (Vhs) (EC 3.1.27.-)
TEG7_VZVD Tegument protein UL51 homolog (ORF7 protein)
TEG6_VZVD Tegument protein UL55 homolog
NEC2_VZVD Nuclear egress protein 2
NEC1_VZVD Nuclear egress protein 1
SCAF_VZVD Capsid scaffolding protein (Protease precursor) (pPR) [Cleaved into: Assemblin (EC 3.4.21.97) ...
US03_VZVD Serine/threonine-protein kinase US3 homolog (Protein kinase ORF66) (EC 2.7.11.1)
TYSY_VZVD Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
UL32_VZVD Packaging protein UL32
TEG5_VZVD Tegument protein UL47 homolog
UNG_VZVD Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
RIR2_VZVD Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
UL13_VZVD Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
VP22_VZVD Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
OBP_VZVD Replication origin-binding protein (OBP) (OriBP)
SCP_VZVD Small capsomere-interacting protein
TRX2_VZVD Triplex capsid protein 2
US10_VZVD Virion protein US10 homolog (Genes 64/69 protein)
GB_VZVD Envelope glycoprotein B (gB)
DPOL_VZVD DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GM_VZVD Envelope glycoprotein M (gM)

1 entry

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3) reference strain

ORF0_VZVO Membrane protein 0 (Membrane ORF0 protein) (ORF S/L)

1 entry

Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus) reference strain

TEG1_EHV4 Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)

2 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus) reference strain

Select_allDeselect_all
US9_CHV9D Envelope protein US9 homolog (Envelope protein 65) (ORF65 protein)
IE61_CHV9D E3 ubiquitin-protein ligase IE61 (EC 2.3.2.27) (Immediate-early protein 61) (IE61)

47 entries

Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
SHUT_EHV1V Virion host shutoff protein (Vhs) (EC 3.1.27.-)
US9_EHV1V Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
UL24_EHV1V Protein UL24 homolog
HELI_EHV1V DNA replication helicase (EC 3.6.4.-)
CEP1_EHV1V Cytoplasmic envelopment protein 1
MB43_EHV1V Membrane protein UL43 homolog (Membrane protein ORF17)
GB_EHV1V Envelope glycoprotein B (gB)
CEP2_EHV1V Cytoplasmic envelopment protein 2
CEP3_EHV1V Cytoplasmic envelopment protein 3
CVC2_EHV1V Capsid vertex component 2
MCP_EHV1V Major capsid protein (MCP)
DPOL_EHV1V DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
DNBI_EHV1V Major DNA-binding protein
ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Infected cell protein 0) (RING-type E3 ubiquitin ...
PAP_EHV1V DNA polymerase processivity factor (Polymerase accessory protein) (PAP)
NP03_EHV1V Nuclear phosphoprotein UL3 homolog (ORF60 protein)
NP04_EHV1V Nuclear protein UL4 homolog
AN_EHV1V Alkaline nuclease (EC 3.1.-.-)
GL_EHV1V Envelope glycoprotein L (gL)
HEPA_EHV1V DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
PRIM_EHV1V DNA primase (EC 2.7.7.-)
PORTL_EHV1V Portal protein
GP2_EHV1V Glycoprotein gp2 (Glycoprotein X) (GpX)
ICP4_EHV1V Major viral transcription factor ICP4 homolog (155 kDa immediate-early protein)
ITP_EHV1V Inner tegument protein
GN_EHV1V Envelope glycoprotein N
OBP_EHV1V Replication origin-binding protein (OBP) (OriBP)
TEG5_EHV1V Tegument protein UL47 homolog (GP10)
SCAF_EHV1V Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
NEC2_EHV1V Nuclear egress protein 2
TEG3_EHV1V Tegument protein UL14 homolog
TRM3_EHV1V Tripartite terminase subunit 3 (EC 3.1.-.-) (Terminase large subunit)
TRM1_EHV1V Tripartite terminase subunit 1
SCP_EHV1V Small capsomere-interacting protein
US03_EHV1V Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
TEG4_EHV1V Tegument protein UL21 homolog
VG01_EHV1V Uncharacterized gene 1 protein
US10_EHV1V Virion protein US10 homolog (Gene 66 protein)
VG75_EHV1V Uncharacterized gene 75 protein
VG59_EHV1V Uncharacterized gene 59 protein
TEG1_EHV1V Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
UL20_EHV1V Protein UL20 homolog
UL13_EHV1V Serine/threonine-protein kinase UL13 homolog (EC 2.7.11.1)
TRX1_EHV1V Triplex capsid protein 1
VG03_EHV1V Gene 3 protein
UNG_EHV1V Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GG_EHV1V Envelope glycoprotein G (gG)

45 entries

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Select_allDeselect_all
VP16_VZVO Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF) (ORF10 protein) (Tegument ...
ICP27_VZVO mRNA export factor ICP27 homolog (Immediate-early protein 4) (IE4)
GK_VZVO Envelope glycoprotein K (Syncytial protein)
GN_VZVO Envelope glycoprotein N
ICP4_VZVO Major viral transcription factor ICP4 homolog (Immediate-early protein 62) (IE62)
GH_VZVO Envelope glycoprotein H (gH)
UL24_VZVO Protein UL24 homolog
DPOL_VZVO DNA polymerase catalytic subunit (EC 2.7.7.7) (EC 3.1.26.4)
GL_VZVO Envelope glycoprotein L (gL)
DNBI_VZVO Major DNA-binding protein
CEP3_VZVO Cytoplasmic envelopment protein 3
AN_VZVO Alkaline nuclease (EC 3.1.-.-)
GE_VZVO Envelope glycoprotein E (gE)
GI_VZVO Envelope glycoprotein I (gI) (Glycoprotein IV) (GPIV)
NP03_VZVO Nuclear phosphoprotein UL3 homolog (ORF58 protein)
ORF1_VZVO Structural protein 1 (Structural ORF1 protein)
MB43_VZVO Membrane protein UL43 homolog (Membrane protein ORF15)
NP04_VZVO Nuclear protein UL4 homolog (ORF56 protein)
GM_VZVO Envelope glycoprotein M (gM)
HELI_VZVO DNA replication helicase (EC 3.6.4.-)
HEPA_VZVO DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
PRIM_VZVO DNA primase (EC 2.7.7.-)
DUT_VZVO Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
ORF32_VZVO Phosphoprotein 32 (ORF32 Phosphoprotein)
LTP_VZVO Large tegument protein deneddylase (EC 3.4.19.12) (EC 3.4.22.-)
ORF2_VZVO Membrane protein 2 (Membrane ORF2 protein)
PAP_VZVO DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) ...
KITH_VZVO Thymidine kinase (EC 2.7.1.21)
ICP22_VZVO Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional ...
TEG4_VZVO Tegument protein UL21 homolog
UNG_VZVO Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
TEG6_VZVO Tegument protein UL55 homolog
TYSY_VZVO Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)
US9_VZVO Envelope protein US9 (Envelope protein 65) (ORF65 protein)
RIR2_VZVO Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TEG5_VZVO Tegument protein UL47 homolog
UL13_VZVO Serine/threonine-protein kinase UL13 homolog (Protein kinase ORF47) (EC 2.7.11.1)
RIR1_VZVO Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
ORF57_VZVO Uncharacterized protein 57 (Uncharacterized ORF57 protein)
TEG1_VZVO Tegument protein UL46 homolog (Tegument protein VP11/12 homolog)
OBP_VZVO Replication origin-binding protein (OBP) (OriBP)
VP22_VZVO Tegument protein VP22 (ORF9 protein) (Tegument protein 9)
TEG3_VZVO Tegument protein UL14 homolog
TEG7_VZVO Tegument protein UL51 homolog (Protein ORF7)
GB_VZVO Envelope glycoprotein B (gB)

19 entries

Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))

Select_allDeselect_all
DUT_SUHVK Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
GH_SUHVK Envelope glycoprotein H (gH)
GL_SUHVK Envelope glycoprotein L (gL)
ICP27_SUHVK mRNA export factor ICP27 homolog (Protein UL54)
ICP4_SUHVK Major viral transcription factor ICP4 homolog
GM_SUHVK Envelope glycoprotein M (gM)
GN_SUHVK Envelope glycoprotein N
GK_SUHVK Envelope glycoprotein K (Syncytial protein)
PAP_SUHVK DNA polymerase processivity factor (Polymerase accessory protein) (PAP) (UL42 homolog)
ICP22_SUHVK Transcriptional regulator ICP22 homolog (Immediate-early protein RSP40)
RIR2_SUHVK Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
KR1_SUHVK Serine/threonine-protein kinase (EC 2.7.11.1)
PRIM_SUHVK DNA primase (EC 2.7.7.-)
UNG_SUHVK Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
RIR1_SUHVK Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
TEG7_SUHVK Tegument protein UL51
SCAF_SUHVK Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) (Virion structural ...
SHUT_SUHVK Virion host shutoff protein (Vhs) (EC 3.1.27.-)
VNUA_SUHVK Probable nuclear antigen

16 entries

Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus)

Select_allDeselect_all
GG_EHV4 Envelope glycoprotein G (gG)
GH_EHV4 Envelope glycoprotein H (gH)
DUT_EHV4 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
KITH_EHV4 Thymidine kinase (EC 2.7.1.21)
GC_EHV4 Envelope glycoprotein C (Glycoprotein 13)
GB_EHV4 Envelope glycoprotein B (gB)
EV45_EHV4 Envelope protein UL45 homolog
RIR1_EHV4 Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
VP16_EHV4 Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)
TEG5_EHV4 Tegument protein UL47 homolog (GP10)
RIR2_EHV4 Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
US10_EHV4 Virion protein US10 homolog (ORF3)
US9_EHV4 Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
UL24_EHV4 Protein UL24 homolog
TEG7_EHV4 Tegument protein UL51 homolog
VP22_EHV4 Tegument protein VP22 (Gene 11 protein)

14 entries

Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
GD_BHV1C Envelope glycoprotein D (gD) (Glycoprotein IV)
GM_BHV1C Envelope glycoprotein M (gM)
GB_BHV1C Envelope glycoprotein B (gB)
GC_BHV1C Envelope glycoprotein C homolog (Glycoprotein GIII)
GN_BHV1C Envelope glycoprotein N
RIR1_BHV1C Ribonucleoside-diphosphate reductase large subunit (R1) (EC 1.17.4.1) (Ribonucleotide reductase ...
HEPA_BHV1C DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
GH_BHV1C Envelope glycoprotein H (gH)
RIR2_BHV1C Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small ...
TEG5_BHV1C Tegument protein UL47
OBP_BHV1C Replication origin-binding protein (OriBP) (OBP)
SCAF_BHV1C Capsid scaffolding protein (Capsid protein P40) (Protease precursor) (pPR) [Cleaved into: Assemblin ...
VP22_BHV1C Tegument protein VP22
UNG_BHV1C Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)

14 entries

Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
GG_EHV1K Envelope glycoprotein G (gG)
ICP27_EHV1K mRNA export factor ICP27 homolog (Transcriptional regulator IE63 homolog)
GP2_EHV1K Glycoprotein gp2 (Glycoprotein X) (GpX)
ICP4_EHV1K Major viral transcription factor (155 kDa immediate-early protein)
KR1_EHV1K Serine/threonine-protein kinase (EC 2.7.11.1)
ICP22_EHV1K Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro ...
GK_EHV1K Envelope glycoprotein K (Syncytial protein)
GD_EHV1K Envelope glycoprotein D (gD) (Glycoprotein 17/18)
VG03_EHV1K Gene 3 protein (ORF L1)
US9_EHV1K Envelope protein US9 homolog (Envelope protein 76) (ORF76 protein)
US10_EHV1K Virion protein US10 homolog (Gene 66 protein) (IR5 protein) (ORF S2-1)
TEG6_EHV1K Tegument protein UL55 homolog
VG67_EHV1K Uncharacterized gene 67 protein (IR6 protein)
US02_EHV1K US1 protein

8 entries

Bovine herpesvirus 1.2 (strain ST) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
GD_BHV1S Envelope glycoprotein D (gD) (Glycoprotein IV)
VGLX_BHV1S Glycoprotein GX
US9_BHV1S Envelope protein US9
US03_BHV1S Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
GE_BHV1S Envelope glycoprotein E (gE)
GI_BHV1S Envelope glycoprotein I (gI)
YOR1_BHV1S Uncharacterized 16.1 kDa protein (ORF1)
US02_BHV1S Protein US2 homolog

8 entries

Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker) (SuHV-1) (Pseudorabies virus (strain Indiana-Funkhauser / Becker))

Select_allDeselect_all
DNBI_SUHVF Major DNA-binding protein
ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Early protein 0) (EP0) (RING-type E3 ubiquitin ...
GL_SUHVF Envelope glycoprotein L (gL)
GC_SUHVF Envelope glycoprotein C homolog (Glycoprotein GIII)
ICP4_SUHVF Major viral transcription factor ICP4 homolog
TRM1_SUHVF Tripartite terminase subunit 1
UNG_SUHVF Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
GB_SUHVF Envelope glycoprotein B (gB)

8 entries

Suid herpesvirus 1 (strain NIA-3) (SuHV-1) (Pseudorabies virus (strain NIA-3))

Select_allDeselect_all
GH_SUHVN Envelope glycoprotein H (gH)
UL20_SUHVN Protein UL20
KITH_SUHVN Thymidine kinase (EC 2.7.1.21)
TEG3_SUHVN Tegument protein UL14
US03_SUHVN Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)
TEG4_SUHVN Tegument protein UL21
US02_SUHVN Protein US2 homolog (28 kDa protein)
UL13_SUHVN Serine/threonine-protein kinase UL13 (EC 2.7.11.1)

6 entries

Equine herpesvirus 1 (strain Kentucky D) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
GD_EHV1D Envelope glycoprotein D (gD) (Glycoprotein 17/18)
EV45_EHV1D Envelope protein UL45 homolog
GC_EHV1D Envelope glycoprotein C (gC) (Glycoprotein 13)
GE_EHV1D Envelope glycoprotein E (gE)
GI_EHV1D Envelope glycoprotein I (gI)
GB_EHV1D Envelope glycoprotein B (gB)

6 entries

Suid herpesvirus 1 (strain Rice) (SuHV-1) (Pseudorabies virus (strain Rice))

Select_allDeselect_all
US9_SUHVR Envelope protein US9 homolog (11 kDa protein)
GG_SUHVR Envelope glycoprotein G (gG)
GI_SUHVR Envelope glycoprotein I (Glycoprotein GP63)
GE_SUHVR Envelope glycoprotein E (gE)
GH_SUHVR Envelope glycoprotein H (gH)
GD_SUHVR Envelope glycoprotein D (gD) (Protein gp50)

3 entries

Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus)

Select_allDeselect_all
GI_CHV9D Envelope glycoprotein I (Membrane glycoprotein 1)
GE_CHV9D Envelope glycoprotein E (Membrane glycoprotein 2) (gE)
US03_CHV9D Serine/threonine-protein kinase US3 homolog (EC 2.7.11.1)

5 entries

Equine herpesvirus 1 (strain AB1) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
GD_EHV1A Envelope glycoprotein D (gD) (Glycoprotein 17/18)
GE_EHV1A Envelope glycoprotein E (gE)
UL32_EHV1A Packaging protein UL32 homolog (Glycoprotein 300) (GP300)
GB_EHV1A Envelope glycoprotein B (gB)
GI_EHV1A Envelope glycoprotein I

5 entries

Equine herpesvirus 1 (strain HVS25A) (EHV-1) (Equine abortion virus)

Select_allDeselect_all
UL24_EHV1 Protein UL24 homolog
GH_EHV1 Envelope glycoprotein H (gH)
KITH_EHV1 Thymidine kinase (EC 2.7.1.21)
TRM1_EHV1 Tripartite terminase subunit 1
GB_EHV1 Envelope glycoprotein B (gB)

4 entries

Bovine herpesvirus 1.1 (strain P8-2) (BoHV-1) (Infectious bovine rhinotracheitis virus)

Select_allDeselect_all
GD_BHV1P Envelope glycoprotein D (gD) (Glycoprotein IV)
TEG5_BHV1P Tegument protein UL47
GB_BHV1P Envelope glycoprotein B (gB)
VP16_BHV1P Tegument protein VP16 homolog (Alpha trans-inducing protein) (Alpha-TIF)

2 entries

Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)

Select_allDeselect_all
GH_FHV1 Envelope glycoprotein H (gH)
KITH_FHV1 Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 1 (strain 6660) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV16 Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 1.1 (strain Jura) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1J E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain K22) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain Q3932) (BoHV-1) (Infectious bovine rhinotracheitis virus)

KITH_BHV1Q Thymidine kinase (EC 2.7.1.21)

1 entry

Bovine herpesvirus 5 (strain N569) (BoHV-5) (Bovine encephalitis herpesvirus)

KITH_BHV5 Thymidine kinase (EC 2.7.1.21)

1 entry

Equine herpesvirus 1 (strain HH1) (EHV-1) (Equine abortion virus)

VG01_EHV1H Uncharacterized gene 1 protein

1 entry

Suid herpesvirus 1 (strain Indiana S) (SuHV-1) (Pseudorabies virus (strain Indiana S))

MCP_SUHVS Major capsid protein (MCP)