Carlavirus (taxid:12163)

VIRION

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Non-enveloped, flexuous, filamentous,470-1000 nm or more long and 12-13 nm in diameter.

GENOME

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Linear ssRNA(+) genome of 5.8-9 kb in size. The 3' terminus is polyadenylated and, in some genera, the 5' end is capped. Encodes 3 to 6 proteins. RBP is a RNA-binding protein.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs).

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Host-virus interaction

Suppression of RNA silencing

Potato virus M cysteine-rich protein (ORF6) and TGBp1 proteins act as suppressors of RNA silencing, the former inhibiting both local and systemic silencing, whereas the latter inhibits systemic silencing .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

32 entries grouped by strain

6 entries

Potato virus M (strain Russian) (PVM) reference strain

Select_allDeselect_all
RDRP_PVMR RNA replication polyprotein (ORF1 protein) [Cleaved into: Helicase (EC 3.6.4.13)] [Includes: Viral ...
TGB1_PVMR Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PVMR Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVMR Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVMR Capsid protein (Coat protein) (CP)
VSR_PVMR RNA silencing suppressor (10.7 kDa protein) (Putative nucleic acid-binding protein)

1 entry

Blueberry scorch virus (BBScV) reference strain

RDRP_BBSCV RNA replication polyprotein (223 kDa protein) (ORF1 protein) [Cleaved into: Helicase (EC 3.6.4.13)] ...

5 entries

Chrysanthemum virus B (CVB)

Select_allDeselect_all
TGB1_CVB Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_CVB Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_CVB Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_CVB Capsid protein (Coat protein) (CP)
VSR_CVB RNA silencing suppressor (12.6 kDa protein) (Putative nucleic acid-binding protein)

5 entries

Lily symptomless virus (LSV)

Select_allDeselect_all
TGB1_LSV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_LSV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_LSV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_LSV Capsid protein (Coat protein) (CP)
VSR_LSV RNA silencing suppressor (16 kDa protein) (ORF6 protein) (Putative nucleic acid-binding protein)

5 entries

Potato virus S (strain Peruvian)

Select_allDeselect_all
TGB1_PVSP Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PVSP Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVSP Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVSP Capsid protein (Coat protein) (CP)
VSR_PVSP RNA silencing suppressor (10.7 kDa protein) (Putative nucleic acid-binding protein)

4 entries

Poplar mosaic virus (isolate ATCC Pv275) (PMV)

Select_allDeselect_all
CAPSD_POPMV Capsid protein (Coat protein) (CP)
TGB1_POPMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_POPMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
VSR_POPMV RNA silencing suppressor (14 kDa protein) (Putative nucleic acid-binding protein)

2 entries

Carnation latent virus (CLV)

Select_allDeselect_all
VSR_CLV RNA silencing suppressor (11.6 kDa protein) (Putative nucleic acid-binding protein)
TGB3_CLV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

2 entries

Helenium virus S (HelVS)

Select_allDeselect_all
CAPSD_HELVS Capsid protein (Coat protein) (CP)
VSR_HELVS RNA silencing suppressor (12.6 kDa protein) (Putative nucleic acid-binding protein)

2 entries

Potato virus M (strain German) (PVM)

Select_allDeselect_all
CAPSD_PVMG Capsid protein (Coat protein) (CP)
VSR_PVMG RNA silencing suppressor (12 kDa protein) (Cysteine-rich protein) (CRP) (Nucleic acid-binding ...
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Aconitum latent virus taxid:101764

Protein ModelArchive
25K ma-jd-viral-22893
Capsid protein (Coat protein) ma-jd-viral-16039
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51979
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61640
RNA silencing suppressor ma-jd-viral-00317

Alfalfa latent virus taxid:165250

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16036
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51957
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61653
TGB1 ma-jd-viral-22868

American hop latent virus taxid:1177630

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-15999
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31108
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61657
RNA silencing suppressor ma-jd-viral-00300
Triple gene block protein 1 ma-jd-viral-22841

Chrysanthemum virus B taxid:12165

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16005
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31113
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39557
Polyprotein ma-jd-viral-15665
Polyprotein ma-jd-viral-31970
Polyprotein ma-jd-viral-23213
Polyprotein ma-jd-viral-19955
Polyprotein ma-jd-viral-46336
Polyprotein ma-jd-viral-52360
Polyprotein ma-jd-viral-65064
Polyprotein ma-jd-viral-60023
RNA silencing suppressor ma-jd-viral-00314
RNA silencing suppressor (12.6 kDa protein) (Putative nucleic acid-binding... ma-jd-viral-00314
Triple gene block 1 Protein (Triple gene block 1o protein) ma-jd-viral-22851

Coleus vein necrosis virus taxid:404404

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16034
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51971
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39562
Nucleic acid binding protein ma-jd-viral-09289
Triple gene block protein 1 ma-jd-viral-22863

Cowpea mild mottle virus taxid:67761

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16011
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31079
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-32081
RNA silencing suppressor ma-jd-viral-00307
Triple gene block 1 (Triple gene block protein 1) ma-jd-viral-22834

Daphne virus S taxid:216614

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16037
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51978
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-50859
RNA silencing suppressor ma-jd-viral-00294
Triple gene block 1 ma-jd-viral-22878

Elderberry carlavirus A taxid:1569052

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16017
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51958
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61642
RNA silencing suppressor ma-jd-viral-00320
Triple gene block protein 1 ma-jd-viral-22875

Elderberry carlavirus B taxid:1569053

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16016
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31095
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39564
RNA silencing suppressor ma-jd-viral-00319
Triple gene block protein 1 ma-jd-viral-22853

Elderberry carlavirus C taxid:1569054

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16043
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51956
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-58016
RNA silencing suppressor ma-jd-viral-00293
Triple gene block protein 1 ma-jd-viral-22844

Elderberry carlavirus D taxid:1569055

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16044
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31092
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61650
RNA silencing suppressor ma-jd-viral-00321
Triple gene block protein 1 ma-jd-viral-22908

Elderberry carlavirus E taxid:1569056

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16001
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51946
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61644
RNA silencing suppressor ma-jd-viral-00301
Triple gene block protein 1 ma-jd-viral-22843

Gaillardia latent virus taxid:1468172

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16038
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51977
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39563
RNA silencing suppressor ma-jd-viral-00304
Triple gene block 1 protein ma-jd-viral-22865

Garlic common latent virus taxid:47900

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16024
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31086
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61654
Nucleic acid binding protein ma-jd-viral-09287
Triple gene block 1 ma-jd-viral-22907

Garlic latent virus taxid:12458

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16027
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51969
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61649
RNA silencing suppressor ma-jd-viral-00318
TGB1 protein ma-jd-viral-22835

Helleborus net necrosis virus taxid:592206

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16041
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51975
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61647
RNA silencing suppressor ma-jd-viral-00323
Triple gene block protein 1 ma-jd-viral-22838

Hippeastrum latent virus taxid:335963

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16013
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31085
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-58020
RNA silencing suppressor ma-jd-viral-00312
Triple gene block 1 protein ma-jd-viral-22909

Hop mosaic virus taxid:142843

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16033
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51940
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39558
RNA silencing suppressor ma-jd-viral-00313
Triple gene block protein 1 ma-jd-viral-22850

Hydrangea chlorotic mottle virus taxid:375546

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-15998
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51941
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-64026
RNA silencing suppressor ma-jd-viral-00311
Triple gene block 1 ma-jd-viral-22827

Jasmine virus C taxid:1853762

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16019
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31104
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-58018
RNA silencing suppressor ma-jd-viral-00299
Triple gene block I (Triple gene block protein I) ma-jd-viral-22871

Kalanchoe latent virus taxid:132477

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16012
Capsid protein (Coat protein) ma-jd-viral-16015
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51942
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-64027
RNA silencing suppressor ma-jd-viral-00296
Triple gene block 1 protein ma-jd-viral-22858

Ligustrum virus A taxid:1899566

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16000
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51951
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61651
RNA silencing suppressor ma-jd-viral-00308
Triple gene block protein 1 ma-jd-viral-22855

Mirabilis jalapa mottle virus taxid:1093773

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16020
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51967
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-64028
RNA silencing suppressor ma-jd-viral-00305
Triple gene block 1 protein ma-jd-viral-22880

Narcissus common latent virus taxid:160844

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16007
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31089
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39568
RNA silencing suppressor ma-jd-viral-00297
Triple Gene Block protein 1 ma-jd-viral-22903

Narcissus symptomless virus taxid:367682

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16002
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31103
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39565
Nucleic acid binding protein ma-jd-viral-09285
Triple gene block protein 1 ma-jd-viral-22826

Nerine latent virus taxid:797075

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16009
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31075
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39569
Nucleic acid binding protein (Nucleotide binding protein) ma-jd-viral-09290
Triple gene block 1 ma-jd-viral-22837

Phlox virus B taxid:475777

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16028
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51939
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61655
Nucleic acid binding protein ma-jd-viral-09292
Triple gene block 1 protein ma-jd-viral-22856

Phlox virus S taxid:436066

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16026
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51943
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39560
RNA silencing suppressor ma-jd-viral-00306
Triple gene block 1 protein ma-jd-viral-22842

Potato latent virus taxid:138982

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16035
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51966
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-50856
RNA silencing suppressor ma-jd-viral-00292
Triple gene block protein 1 ma-jd-viral-22885

Potato rough dwarf virus taxid:106118

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16031
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51983
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61639
RNA silencing suppressor ma-jd-viral-00298
Triple block protein 1 ma-jd-viral-22846

Potato virus H taxid:1046402

Protein ModelArchive
26K protein ma-jd-viral-22836
Capsid protein (Coat protein) ma-jd-viral-16042
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51945
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39556
RNA silencing suppressor ma-jd-viral-00322

Potato virus P taxid:329164

Protein ModelArchive
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51983
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61639
Triple gene block protein 1 ma-jd-viral-22846

Potato virus S taxid:12169

Protein ModelArchive
25K protein ma-jd-viral-22887
Capsid protein (Coat protein) ma-jd-viral-16010
Capsid protein (Coat protein) ma-jd-viral-16032
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51970
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61646
RNA silencing suppressor ma-jd-viral-00310

Red clover vein mosaic virus taxid:590403

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16014
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-31094
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39559
Nucleic acid binding protein ma-jd-viral-09283
Triple gene block 1 ma-jd-viral-22866

Sweet potato C6 virus taxid:1307958

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16025
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51961
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-61652
TGB1 (Triple gene block protein 1) ma-jd-viral-22845

Yam latent virus taxid:1592930

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-16021
Movement protein TGB2 (Triple gene block 2 protein) ma-jd-viral-51954
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) ma-jd-viral-39567
RNA silencing suppressor ma-jd-viral-00303
Triple gene block protein 1 ma-jd-viral-22832