Foveavirus (taxid:129725)

VIRION

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Non-enveloped, flexuous, filamentous,800 nm or more long and 12-13 nm in diameter.

GENOME

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Linear ssRNA(+) genome of 8.4-9.3 kb in size. The 3' terminus is polyadenylated and 5'end is capped. Encodes for 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as subgenomic mRNAs (sgRNAs).

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

5 entries grouped by protein

1 entry

Capsid protein (CP) (Coat protein)

CAPSD_ASPVP
Apple stem pitting virus (isolate PA66) (ASPV) reference strain

1 entry

RNA replication polyprotein (ORF1 protein)

RDRP_ASPVP
Apple stem pitting virus (isolate PA66) (ASPV) reference strain

1 entry

Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block 1 protein) (TGBp1)

TGB1_ASPVP
Apple stem pitting virus (isolate PA66) (ASPV) reference strain

1 entry

Movement protein TGB2 (Triple gene block 2 protein) (TGBp2)

TGB2_ASPVP
Apple stem pitting virus (isolate PA66) (ASPV) reference strain

1 entry

Movement protein TGBp3 (Triple gene block 3 protein) (TGBp3)

TGB3_ASPVP
Apple stem pitting virus (isolate PA66) (ASPV) reference strain