Potexvirus (taxid:12176)

VIRION

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Non-enveloped, flexuous, filamentous, 470-1000 nm or more long and 12-13 nm in diameter.

GENOME

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Linear ssRNA(+) genome of 5.9-7 kb in size. The 5' end is capped and 3' terminus is polyadenylated. Encodes for 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs). TGB3 is expressed by leaky scanning of the TGB2 subgenomic mRNA.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Host-virus interaction

Suppression of RNA silencing

Potato virus X TGBp1 protein functions as a suppressor of RNA silencing inhibiting the PTGS pathway .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

77 entries grouped by strain

7 entries

Papaya mosaic potexvirus (PMV) reference strain

Select_allDeselect_all
RDRP_PMV RNA replication protein (176 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_PMV Coat protein (Capsid protein) (CP)
TGB1_PMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
Y15K_PMV Uncharacterized 14.7 kDa protein in coat protein coding strand
Y14K_PMV Uncharacterized 14.1 kDa protein in ORF1 coding strand

6 entries

Indian citrus ringspot virus (isolate Kinnow mandarin/India/K1/1996) (ICRSV) reference strain

Select_allDeselect_all
RDRP_ICRSV RNA replication protein [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); Helicase (EC ...
TGB3_ICRSV Movement protein TGBp3 (Triple gene block 3 protein) (TGBp3)
TGB2_ICRSV Movement protein TGB2 (Triple gene block 2 protein) (TGBp2)
TGB1_ICRSV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
CAPSD_ICRSV Capsid protein (CP) (Coat protein)
VNBP_ICRSV 23kDa protein (Putative 23 kDa nucleic acid binding protein)

6 entries

Narcissus mosaic virus (NMV) reference strain

Select_allDeselect_all
RDRP_NMV RNA replication protein (186 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_NMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_NMV Movement protein TGB2 (14 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_NMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_NMV Coat protein (Capsid protein) (CP)
YOR6_NMV Uncharacterized 10 kDa protein (ORF 6)

5 entries

Foxtail mosaic virus reference strain

Select_allDeselect_all
RDRP_FXMV RNA replication protein (152 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_FXMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_FXMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_FXMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_FXMV Coat protein (Capsid protein) (CP)

5 entries

Plantago asiatica mosaic potexvirus (P1AMV) reference strain

Select_allDeselect_all
RDRP_P1AMV RNA replication protein (156 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_P1AMV Coat protein (Capsid protein) (CP)
TGB1_P1AMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_P1AMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_P1AMV Movement protein TGBp3 (13 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Potato virus X (strain X3) (PVX) reference strain

Select_allDeselect_all
RDRP_PVXX3 RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_PVXX3 Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PVXX3 Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVXX3 Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVXX3 Coat protein (Capsid protein) (CP)

5 entries

Strawberry mild yellow edge-associated virus (SMYEaV) reference strain

Select_allDeselect_all
RDRP_SMYEA RNA replication protein (150 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_SMYEA Coat protein (Capsid protein) (CP)
TGB2_SMYEA Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB1_SMYEA Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_SMYEA Movement protein TGBp3 (8.1 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

White clover mosaic virus (strain M) (WCMV) reference strain

Select_allDeselect_all
RDRP_WCMVM RNA replication protein (147 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_WCMVM Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_WCMVM Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVM Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_WCMVM Coat protein (Capsid protein) (CP)

5 entries

Potato virus X (PVX)

Select_allDeselect_all
RDRP_PVX RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_PVX Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_PVX Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVX Coat protein (Capsid protein) (CP)
TGB2_PVX Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)

5 entries

Potato virus X (strain CP) (PVX)

Select_allDeselect_all
RDRP_PVXCP RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_PVXCP Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PVXCP Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_PVXCP Coat protein (Capsid protein) (CP)
TGB3_PVXCP Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Potato virus X (strain HB) (PVX)

Select_allDeselect_all
RDRP_PVXHB RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_PVXHB Coat protein (Capsid protein) (CP)
TGB3_PVXHB Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)
TGB1_PVXHB Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PVXHB Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)

5 entries

White clover mosaic virus (strain O) (WCMV)

Select_allDeselect_all
RDRP_WCMVO RNA replication protein (147 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_WCMVO Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_WCMVO Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVO Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_WCMVO Coat protein (Capsid protein) (CP)

3 entries

Clover yellow mosaic virus (CYMV)

Select_allDeselect_all
TGB3_CYMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_CYMV Coat protein (Capsid protein) (CP)
Y5K_CYMV Uncharacterized 5.8 kDa protein

3 entries

Cymbidium mosaic virus (strain Singapore)

Select_allDeselect_all
CAPSD_CMVSI Coat protein (Capsid protein) (CP)
TGB3_CMVSI Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)
Y12K_CMVSI Uncharacterized 12.4 kDa protein

3 entries

Lily virus X

Select_allDeselect_all
TGB1_LVX Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_LVX Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_LVX Coat protein (Capsid protein) (CP)

2 entries

Potato virus X (strain Xc) (PVX)

Select_allDeselect_all
CAPSD_PVXXC Coat protein (Capsid protein) (CP)
TGB3_PVXXC Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

1 entry

Potato aucuba mosaic virus (PAMV)

CAPSD_PAMV Coat protein (Capsid protein) (CP)

1 entry

Potato virus X (strain UK3) (PVX)

CAPSD_PVXU3 Coat protein (Capsid protein) (CP)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Asparagus virus 3 taxid:445435

Protein ModelArchive
Coat protein ma-jd-viral-15983
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-63898
Triple gene block protein 1 ma-jd-viral-22904
Triple gene block protein 2 ma-jd-viral-51953

Cactus virus X taxid:112227

Protein ModelArchive
12 kDa protein ma-jd-viral-31093
15 kDa protein ma-jd-viral-58844
25 kDa protein (Triple gene block protein 1) ma-jd-viral-22892
8 kDa protein ma-jd-viral-30405
Coat protein ma-jd-viral-15994
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-44045

Citrus yellow vein clearing virus taxid:1214459

Protein ModelArchive
12 kDa triple gene block protein (12kDa triple gene block protein) ma-jd-viral-31116
25kDa Triple gene block protein ma-jd-viral-22860
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-61641
ORF6 (Putative 23 kDa nucleic acid binding protein) (Putative 23kDa nucleic acid binding... ma-jd-viral-33519
Potexviruses and carlaviruses coat protein domain-containing protein ma-jd-viral-16030

Indian citrus ringspot virus (isolate Kinnow mandarin/India/K1/1996) taxid:651357

Protein ModelArchive
23kDa protein (Putative 23 kDa nucleic acid binding protein) ma-jd-viral-33518
Capsid protein (CP) (Coat protein) ma-jd-viral-16003
Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block 1 protein)... ma-jd-viral-22879
Movement protein TGB2 (Triple gene block 2 protein) (TGBp2) ma-jd-viral-31084
Movement protein TGBp3 (Triple gene block 3 protein) (TGBp3) ma-jd-viral-61656

Lettuce virus X taxid:447171

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-15966
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-63897
Triple gene block 1 protein (Triple-gene-block protein 1) ma-jd-viral-22861
Triple-gene-block-protein 2 ma-jd-viral-31077

Pepino mosaic virus taxid:112229

Protein ModelArchive
CP (Capsid protein) (Coat protein) ma-jd-viral-15968
Coat protein ma-jd-viral-15968
Coat protein ma-jd-viral-15968
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-63899
Orf3 (TBG2 protein) (TGB2) (TGBp2) (Triple gene block 2) (Triple gene block protein... ma-jd-viral-51982
RNA replication protein (EC 2.7.7.48) (EC 3.6.4.13) ma-jd-viral-34096
TGB1 protein (Triple gene block protein 1) ma-jd-viral-22888

Phaius virus X taxid:457382

Protein ModelArchive
Coat protein ma-jd-viral-15980
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-39038
RNA replication protein (EC 2.7.7.48) (EC 3.6.4.13) ma-jd-viral-34095
Triple gene block protein 1 ma-jd-viral-22899
Triple gene block protein 2 ma-jd-viral-31105

Pitaya virus X taxid:1176736

Protein ModelArchive
CP ma-jd-viral-15990
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-44044
TGB1 ma-jd-viral-22874
TGB2 ma-jd-viral-31087

Plantain virus X taxid:1331744

Protein ModelArchive
Coat protein ma-jd-viral-15978
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-63900
Putative 10 kDa protein ma-jd-viral-65439
Triple gene block protein 1 ma-jd-viral-22849
Triple gene block protein 2 ma-jd-viral-51972

Potexvirus alternantherae taxid:85454

Protein ModelArchive
Coat protein ma-jd-viral-15985
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-49529
Triple gene block 1 protein 26k ma-jd-viral-22895
Triple gene block 2 protein ma-jd-viral-31114

Potexvirus ecsallii taxid:317027

Protein ModelArchive
Coat protein ma-jd-viral-15974
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-08951
Tgb1 ma-jd-viral-22896
Tgb2 ma-jd-viral-31101

Senna mosaic virus taxid:1881013

Protein ModelArchive
CP ma-jd-viral-15979
TGB1 ma-jd-viral-22830
TGB2 ma-jd-viral-31082
TGB3 ma-jd-viral-49528

Tamus red mosaic virus taxid:1081702

Protein ModelArchive
Coat protein ma-jd-viral-16004
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-08950
Tgb1 ma-jd-viral-22852
Tgb2 ma-jd-viral-31110

Yam virus X taxid:1503864

Protein ModelArchive
Coat protein ma-jd-viral-15967
Movement protein TGBp3 (Triple gene block 3 protein) ma-jd-viral-33841
RNA replication protein (EC 2.7.7.48) (EC 3.6.4.13) ma-jd-viral-34099
Triple gene block 1 ma-jd-viral-22873
Triple gene block 2 ma-jd-viral-31109