Potexvirus

VIRION

Non-enveloped, flexuous, filamentous, 470-1000 nm or more long and 12-13 nm in diameter.

GENOME

Linear ssRNA(+) genome of 5.9-7 kb in size. The 5' end is capped and 3' terminus is polyadenylated. Encodes for 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs). TGB3 is expressed by leaky scanning of the TGB2 subgenomic mRNA.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Host-virus interaction

Suppression of RNA silencing

Potato virus X TGBp1 protein functions as a suppressor of RNA silencing inhibiting the PTGS pathway .

Matching UniProtKB/Swiss-Prot entries

71 entries grouped by strain (browse by keywords)

All proteins are shown (view only 58 complete proteome entries)

7 entries

Papaya mosaic potexvirus (PMV) reference strain

Select_allDeselect_all
RDRP_PMV RNA replication protein (176 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
Y14K_PMV Uncharacterized 14.1 kDa protein in ORF1 coding strand
Y15K_PMV Uncharacterized 14.7 kDa protein in coat protein coding strand
TGB1_PMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_PMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PMV Coat protein (Capsid protein) (CP)

6 entries

Narcissus mosaic virus (NMV) reference strain

Select_allDeselect_all
YOR6_NMV Uncharacterized 10 kDa protein (ORF 6)
TGB2_NMV Movement protein TGB2 (14 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB1_NMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_NMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
RDRP_NMV RNA replication protein (186 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_NMV Coat protein (Capsid protein) (CP)

5 entries

Foxtail mosaic virus reference strain

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RDRP_FXMV RNA replication protein (152 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_FXMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_FXMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
TGB2_FXMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_FXMV Coat protein (Capsid protein) (CP)

5 entries

Plantago asiatica mosaic potexvirus (P1AMV) reference strain

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RDRP_P1AMV RNA replication protein (156 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_P1AMV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_P1AMV Movement protein TGBp3 (13 kDa protein) (Triple gene block 3 protein) (TGBp3)
TGB2_P1AMV Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_P1AMV Coat protein (Capsid protein) (CP)

5 entries

Potato virus X (strain X3) (PVX) reference strain

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RDRP_PVXX3 RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_PVXX3 Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_PVXX3 Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
TGB2_PVXX3 Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_PVXX3 Coat protein (Capsid protein) (CP)

5 entries

Strawberry mild yellow edge-associated virus (SMYEaV) reference strain

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RDRP_SMYEA RNA replication protein (150 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_SMYEA Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_SMYEA Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_SMYEA Movement protein TGBp3 (8.1 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_SMYEA Coat protein (Capsid protein) (CP)

5 entries

White clover mosaic virus (strain M) (WCMV) reference strain

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RDRP_WCMVM RNA replication protein (147 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_WCMVM Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_WCMVM Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVM Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_WCMVM Coat protein (Capsid protein) (CP)

5 entries

Potato virus X (PVX)

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RDRP_PVX RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB2_PVX Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB1_PVX Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_PVX Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVX Coat protein (Capsid protein) (CP)

5 entries

Potato virus X (strain CP) (PVX)

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TGB2_PVXCP Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB1_PVXCP Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_PVXCP Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
RDRP_PVXCP RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
CAPSD_PVXCP Coat protein (Capsid protein) (CP)

5 entries

Potato virus X (strain HB) (PVX)

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RDRP_PVXHB RNA replication protein (165 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB2_PVXHB Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB1_PVXHB Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB3_PVXHB Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVXHB Coat protein (Capsid protein) (CP)

5 entries

White clover mosaic virus (strain O) (WCMV)

Select_allDeselect_all
RDRP_WCMVO RNA replication protein (147 kDa protein) (ORF1 protein) [Includes: RNA-directed RNA polymerase (EC ...
TGB1_WCMVO Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_WCMVO Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVO Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_WCMVO Coat protein (Capsid protein) (CP)

3 entries

Clover yellow mosaic virus (CYMV)

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Y5K_CYMV Uncharacterized 5.8 kDa protein
TGB3_CYMV Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_CYMV Coat protein (Capsid protein) (CP)

3 entries

Cymbidium mosaic virus (strain Singapore)

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Y12K_CMVSI Uncharacterized 12.4 kDa protein
TGB3_CMVSI Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_CMVSI Coat protein (Capsid protein) (CP)

3 entries

Lily virus X

Select_allDeselect_all
TGB1_LVX Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_LVX Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
CAPSD_LVX Coat protein (Capsid protein) (CP)

2 entries

Potato virus X (strain Xc) (PVX)

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TGB3_PVXXC Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
CAPSD_PVXXC Coat protein (Capsid protein) (CP)

1 entry

Potato aucuba mosaic virus (PAMV)

CAPSD_PAMV Coat protein (Capsid protein) (CP)

1 entry

Potato virus X (strain UK3) (PVX)

CAPSD_PVXU3 Coat protein (Capsid protein) (CP)