Alphafusellovirus (taxid:10475)

VIRION

Enveloped, spindle-shaped, with short tail fibers attached to one pole. The virion is about 60 nm in diameter and 100 nm in length.

GENOME

Circular, supercoiled dsDNA genome of 14.8 to 17.3kb, encodes for 31 to 37 genes.

GENE EXPRESSION

Genomic DNA is specifically integrated into a tRNA gene of the host chromosome.

REPLICATION

CYTOPLASMIC

1. Attachment to target cell adhesion receptors
2. Penetration into host cytoplasm
3. Viral genome is integrated into a tRNA gene of host chromosome
4. Transcription and translation of early genes
5. Replication of genomic DNA
6. Transcription and translation of late genes
7. Genomic DNA is packaged in new virions
8. Mature virions are released from the cell by budding