Human immunodeficiency virus 1 (taxid:11676)

Molecular biology

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Enveloped, spherical to pleomorphic in shape, 80-100 nm in diameter. Mature capsid contains 1572 capsid proteins.

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Monopartite, linear, dimeric, ssRNA(+) genome of 9,75 kb, with a 5'-cap and a 3'poly-A tail. There are two long terminal repeats (LTRs) of about 600nt long at the 5' and 3' ends. The LTRs contain the U3, R, and U5 regions. There are also a primer binding site (PBS) at the 5'end and a polypurine tract (PPT) at the 3'end.

GENE EXPRESSION

The integrated provirus utilizes the promotor elements in the 5' LTR to drive transcription. This gives rise to the unspliced full length mRNA that will serve as genomic RNA to be packaged into virions or used as a template for translation of gag and gag-(pro)pol (1 ribosomal frameshift) polyproteins. The uncompletely spliced mRNAs encode env that is cleaved into SU and TM envelope proteins, and the accessory proteins vif, vpu, and vpr. Completely spliced mRNAs encode Rev, Tat and Nef accessory proteins. Rev escorts unspliced and uncompletely spliced RNAs out of the nucleus of infected cells.

ENZYMES

REPLICATION

NUCLEAR

Lytic replication:

  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell's genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Latent replication : replication as a provirus integrated in the host chromosome.

Reference strains

HIV-1 REFERENCE STRAIN HIV-1 subtype B strain HxB2
Sequence | Genome | Proteome

EXPERIMENTAL CLONE PNL4.3 pNL4-3 is a subtype B strain that is normally used as the reference sequence for HIV drug resistance studies. It is a recombinant (infectious) proviral clone that contains DNA from HIV isolates NY5 (5' half) and BRU (3' half). The site of recombination is the EcoRI site at positions 5743-5748.
Sequence | Proteome

GROUP O REFERENCE STRAIN Group O seems to be endemic and largely confined to Cameroon and neighboring countries in West Central Africa, where these viruses represent a small minority of HIV-1 strains. (Pubmed)

HIV-1 isolate ANT70
Sequence | Proteome

GROUP N REFERENCE STRAIN The group N is confined to Cameroon. (Pubmed)

HIV-1 isolate YBF30
Sequence | Proteome
GROUP M REFERENCE STRAINS

HIV-1 group M is responsible for the worlwide pandemy of AIDS. It is subdivised into 9 subtypes (A-F), and several CRF.
(Reference strains have been chosen in collaboration with Tulio de Oliveira, Bioafrica.net)

Subtype A1: HIV-1 isolate U455
Sequence | Proteome

Subtype B: HIV-1 strain HxB2
Sequence | Genome | Proteome

Subtype C: HIV-1 isolate TV001
Sequence | Proteome

Subtype D: HIV-1 isolate ELI
Sequence | Proteome

Subtype F1: HIV-1 isolate 93BR020
Sequence | Proteome

Subtype F2: HIV-1 isolate MP255
Sequence | Proteome

Subtype G: HIV-1 isolate 92BR025
Sequence | Proteome

Subtype H: HIV-1 isolate 90CF056
Sequence | Proteome

Subtype J: HIV-1 isolate SE9173
Sequence | Proteome

Subtype K: HIV-1 isolate 96CM-MP535
Sequence | Proteome

CRF01_AE: HIV-1 isolate 90CF11697
Sequence | Proteome

CRF02_AG: HIV-1 isolate 97CM.MP807
Sequence | Proteome

Epidemiology

Global map of HIV infection source WHO/UNAIDS

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HIV subtypes

HIV viruses are subdivised into groups, subtypes and CRF. Groups N and O are recent and so far restricted to cameroon. The vast majority of HIV-1 strains found worldwide belongs to Group M (Major). This group is subdivised into 9 subtypes (A-F), and several CRF (circulating recombinant form).

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Source Peeters, M.

Replication cycle

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  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell's genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

353 entries grouped by protein

49 entries

Envelope glycoprotein gp160 (Env polyprotein)

Select_allDeselect_all
ENV_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
ENV_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
ENV_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
ENV_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
ENV_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
ENV_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
ENV_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
ENV_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
ENV_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
ENV_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
ENV_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
ENV_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
ENV_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
ENV_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
ENV_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
ENV_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
ENV_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
ENV_HV1B8
Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
ENV_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
ENV_HV1BN
Human immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
ENV_HV1C4
Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
ENV_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
ENV_HV1J3
Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
ENV_HV1KB
Human immunodeficiency virus type 1 group M subtype B (isolate KB-1/ETR) (HIV-1)
ENV_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
ENV_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
ENV_HV1MF
Human immunodeficiency virus type 1 group M subtype B (isolate MFA) (HIV-1)
ENV_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
ENV_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
ENV_HV1N5
Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)

Truncated surface protein (SU) (Glycoprotein 120) (gp120)

ENV_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
ENV_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
ENV_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
ENV_HV1S1
Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
ENV_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
ENV_HV1S3
Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
ENV_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
ENV_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
ENV_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
ENV_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
ENV_HV1W1
Human immunodeficiency virus type 1 group M subtype B (isolate WMJ1) (HIV-1)
ENV_HV1W2
Human immunodeficiency virus type 1 group M subtype B (isolate WMJ22) (HIV-1)
ENV_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
ENV_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
ENV_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)
ENV_HV1Z3
Human immunodeficiency virus type 1 group M subtype U (isolate Z3) (HIV-1)

Truncated surface protein (SU) (Glycoprotein 120) (gp120)

ENV_HV1Z6
Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
ENV_HV1Z8
Human immunodeficiency virus type 1 group M subtype D (isolate Z84) (HIV-1)
ENV_HV1ZH
Human immunodeficiency virus type 1 group M subtype A (isolate Z321) (HIV-1)

38 entries

Gag polyprotein (Pr55Gag)

Select_allDeselect_all
GAG_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
GAG_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
GAG_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
GAG_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
GAG_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
GAG_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
GAG_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
GAG_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
GAG_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
GAG_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
GAG_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
GAG_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
GAG_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
GAG_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
GAG_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
GAG_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
GAG_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
GAG_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
GAG_HV1B5
Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
GAG_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
GAG_HV1C4
Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
GAG_HV1J3
Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
GAG_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
GAG_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
GAG_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
GAG_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
GAG_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
GAG_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
GAG_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
GAG_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
GAG_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
GAG_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
GAG_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
GAG_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
GAG_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
GAG_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
GAG_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)

42 entries

Protein Nef (3'ORF) (Negative factor) (F-protein)

Select_allDeselect_all
NEF_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
NEF_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
NEF_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
NEF_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
NEF_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
NEF_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
NEF_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
NEF_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
NEF_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
NEF_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
NEF_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
NEF_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
NEF_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
NEF_HV112
Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
NEF_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
NEF_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
NEF_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
NEF_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
NEF_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
NEF_HV1B8
Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
NEF_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
NEF_HV1BN
Human immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
NEF_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
NEF_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
NEF_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
NEF_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
NEF_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
NEF_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
NEF_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
NEF_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
NEF_HV1S1
Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
NEF_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
NEF_HV1S3
Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
NEF_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
NEF_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
NEF_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
NEF_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
NEF_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
NEF_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
NEF_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
NEF_HV1Z6
Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
NEF_HV1ZH
Human immunodeficiency virus type 1 group M subtype A (isolate Z321) (HIV-1)

36 entries

Gag-Pol polyprotein (Pr160Gag-Pol)

Select_allDeselect_all
POL_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
POL_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
POL_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
POL_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
POL_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
POL_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
POL_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
POL_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
POL_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
POL_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
POL_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
POL_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
POL_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
POL_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
POL_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
POL_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
POL_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
POL_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)

pdb 1A9M; 1AJV; 1AJX; 1AXA; 1BQM; 1BQN; 1D4H; 1D4I; 1D4J; 1DLO; 1DW6; 1EBK; 1EBW; 1EBY; 1EBZ; 1EC0; 1EC1; 1EC2; 1EC3; 1EET; 1G35; 1GNM; 1GNN; 1GNO; 1HAR; 1HBV; 1HEF; 1HEG; 1HIH; 1HMV; 1HNI; 1HNV; 1HOS; 1HPS; 1HPZ; 1HQE; 1HQU; 1HRH; 1HTE; 1HTF; 1HTG; 1HVI; 1HVK; 1HVU; 1HYS; 1IKV; 1IKW; 1IKX; 1IKY; 1J5O; 1KJH; 1MER; 1MES; 1MET; 1MEU; 1N5Y; 1N6Q; 1NPA; 1NPV; 1NPW; 1QE1; 1QMC; 1R0A; 1RDH; 1RTD; 1S6P; 1S6Q; 1S9E; 1S9G; 1SBG; 1SUQ; 1SV5; 1T03; 1T05; 1T7K; 1TV6; 1TVR; 1UWB; 1W5V; 1W5W; 1W5X; 1W5Y; 1YT9; 1ZP8; 1ZPA; 1ZSF; 1ZSR; 2AQU; 2B5J; 2B6A; 2BAN; 2BBB; 2BE2; 2EXF; 2G69; 2HB3; 2HMI; 2HNZ; 2HS1; 2HS2; 2I4D; 2I4U; 2I4V; 2I4W; 2I4X; 2I5J; 2IAJ; 2IC3; 2IDW; 2IEO; 2JZW; 2L45; 2L46; 2L4L; 2UXZ; 2UY0; 2VG5; 2VG6; 2VG7; 2X4U; 2YKM; 2YKN; 2ZD1; 2ZE2; 3AVI; 3BGR; 3DLK; 3GGA; 3GGV; 3GGX; 3HVT; 3IG1; 3IRX; 3IS9; 3ISN; 3ITH; 3JSM; 3JYT; 3K2P; 3K4V; 3KLE; 3KLF; 3KLG; 3KLH; 3KLI; 3NDT; 3NU3; 3NU4; 3NU5; 3NU6; 3NU9; 3NUJ; 3NUO; 3OK9; 3PSU; 3QAA; 3QLH; 3QO9; 3TKG; 3TKW; 3TL9; 3TLH; 3V4I; 3V6D; 3V81; 3ZPS; 3ZPT; 3ZPU; 4COE; 4CP7; 4CPQ; 4CPR; 4CPS; 4CPT; 4CPU; 4CPW; 4CPX; 4DG1; 4G1Q; 4G8G; 4G8I; 4G9D; 4G9F; 4H4M; 4H4O; 4I2P; 4I2Q; 4ICL; 4ID5; 4IDK; 4IFV; 4IFY; 4IG0; 4IG3; 4KFB; 4KKO; 4KO0; 4LSL; 4LSN; 4MFB; 4O44; 4O4G; 4OJR; 4PQU; 4PUO; 4PWD; 4Q0B; 4QAG; 4R5P; 4RW4; 4RW6; 4RW7; 4RW8; 4RW9; 4U8W; 4WE1; 4YE3; 4YHQ; 4ZIP; 4ZLS; 5AGZ; 5AH6; 5AH7; 5AH8; 5AH9; 5AHA; 5AHB; 5AHC; 5BRY; 5BS4; 5C24; 5C25; 5C42; 5CYM; 5CYQ; 5D3G; 5FDL; 5HBM; 5HLF; 5HP1; 5HRO; 5I3U; 5I42; 5J1E; 5JFP; 5JFU; 5JG1; 5OI2; 5OI3; 5OI5; 5OI8; 5OIA; 5T6Z; 5T70; 5TER; 5TUQ; 5TW3; 5TXL; 5TXM; 5TXN; 5TXO; 5TXP; 5UFZ; 5ULT; 5UOV; 5UPZ; 5UV5; 5V5L; 5V5M; 5VQQ; 5VQR; 5VQS; 5VQT; 5VQU; 5VQV; 5VQW; 5VQX; 5VQY; 5VQZ; 5W5W; 5YOJ; 6AMO; 6AN2; 6AN8; 6ANQ; 6AOC; 6ASW; 6AVM; 6AVT; 6B19; 6BZ2; 6C0J; 6C0K; 6C0L; 6C0N; 6C0O; 6C0P; 6C0R; 6C8X; 6C8Y; 6CGF; 6D0D; 6D0E; 6DTW; 6DTX; 6DUF; 6DUG; 6DUH; 6ECL; 6ELI; 6HAK; 6KMP; 6O48; 6O9E; 6OE3; 6OUN; 6PRF; 6UL5; 6VUG; 6WAZ; 6WB0; 6WB1; 6WB2; 6X47; 6X49; 6X4A; 6X4B; 6X4C; 6X4D; 6X4E; 6X4F; 7AHX; 7AID; 7AIF; 7AIG; 7AII; 7AIJ; 7KJV; 7KJW; 7KJX; 7KRC; 7KRD; 7KRE; 7KRF; 7KWU; 7LPW; 7LPX; 7LQU; 7LRI; 7LRM; 7LRX; 7LRY; 7LSK; 7OT6; 7OTA; 7OTK; 7OTN; 7OTX; 7OTZ; 7OUT; 7OXQ; 7OZ2; 7OZ5; 7OZW; 7P15; 7SEP; 7SIF; 7SIG; 7SIH; 7SJX; 7SNL; 7SNN; 7SNP; 7SNQ; 7SNZ; 7SO1; 7SO2; 7SO3; 7SO4; 7SO6; 7TAZ; 7U5Z; 7Z24; 7Z29; 7Z2D; 7Z2E; 7Z2G; 7Z2H; 8DX2; 8DX3; 8DX8; 8DXB; 8DXE; 8DXG; 8DXH; 8DXI; 8DXJ; 8DXK; 8DXL; 8DXM; 8FE8; 8FFX; 8STP; 8STQ; 8STR; 8STS; 8STT; 8STU; 8STV; 8U69; 8U6A; 8U6B; 8U6C; 8U6D; 8U6E; 8U6F; 8U6G; 8U6H; 8U6I; 8U6J; 8U6K; 8U6L; 8U6M; 8U6N; 8U6O; 8U6P; 8U6Q; 8U6R; 8U6S; 8U6T

POL_HV1B5
Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
POL_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
POL_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
POL_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
POL_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
POL_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
POL_HV1N5
Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)

pdb 1A43; 1A8O; 1AFV; 1AK4; 1AUM; 1B92; 1B9D; 1B9F; 1BAJ; 1BHL; 1BI4; 1BIS; 1BIU; 1BIZ; 1BL3; 1GWP; 1HIW; 1HYV; 1HYZ; 1ITG; 1K6Y; 1M9D; 1QS4; 1UPH; 1WJB; 1WJD; 2B4J; 2GOL; 2GON; 2H3F; 2H3I; 2H3Q; 2H3V; 2H3Z; 2HMX; 2HVP; 2ITG; 2JPR; 2JYG; 2JYL; 2LF4; 2LYA; 2LYB; 2M3Z; 2M8L; 2M8N; 2M8P; 2ONT; 2PWM; 2PWO; 2PXR; 2X2D; 2XDE; 2XV6; 2XXM; 3AV9; 3AVA; 3AVB; 3AVC; 3AVF; 3AVG; 3AVH; 3AVJ; 3AVK; 3AVL; 3AVM; 3AVN; 3DIK; 3DPH; 3DS0; 3DS1; 3DS2; 3DS3; 3DS4; 3DS5; 3DTJ; 3GV2; 3H47; 3H4E; 3L3U; 3L3V; 3LPT; 3LPU; 3LRY; 3MGE; 3NF6; 3NF7; 3NF8; 3NF9; 3NFA; 3P05; 3P0A; 3S85; 3WNE; 3WNF; 3WNG; 3WNH; 3ZCM; 3ZSO; 3ZSQ; 3ZSR; 3ZSV; 3ZSW; 3ZSX; 3ZSY; 3ZSZ; 3ZT0; 3ZT1; 3ZT2; 3ZT3; 3ZT4; 4AH9; 4AHR; 4AHS; 4AHT; 4AHU; 4AHV; 4CE9; 4CEA; 4CEB; 4CEC; 4CED; 4CEE; 4CEF; 4CEO; 4CEQ; 4CER; 4CES; 4CEZ; 4CF0; 4CF1; 4CF2; 4CF8; 4CF9; 4CFA; 4CFB; 4CFC; 4CFD; 4CGD; 4CGF; 4CGG; 4CGH; 4CGI; 4CGJ; 4CHN; 4CHO; 4CHP; 4CHQ; 4CHY; 4CHZ; 4CIE; 4CIF; 4CIG; 4CJ3; 4CJ4; 4CJ5; 4CJE; 4CJF; 4CJK; 4CJL; 4CJP; 4CJQ; 4CJR; 4CJS; 4CJT; 4CJU; 4CJV; 4CJW; 4CK1; 4CK2; 4CK3; 4COC; 4COP; 4DGA; 4DGE; 4DMN; 4E1M; 4E1N; 4E91; 4E92; 4GVM; 4GW6; 4ID1; 4IPY; 4JLH; 4JMU; 4LH4; 4LH5; 4LQW; 4NX4; 4O0J; 4O55; 4O5B; 4OVL; 4PHV; 4QNB; 4WYM; 4Y1C; 4Y1D; 4ZHR; 5HVP; 5JL4; 5KGW; 5KGX; 5KRS; 5KRT; 5TEO; 5U1C; 5VCK; 5VEA; 5VJ3; 5XN0; 5XN1; 5XN2; 6ES8; 6IK9; 6IKA; 6JCF; 6JCG; 6KDJ; 6KDK; 6KDM; 6KDN; 6KDO; 6LMI; 6LMQ; 6MCR; 6MCS; 6OOS; 6OOT; 6OOU; 6OPW; 6OPY; 6OPZ; 6OXO; 6OXP; 6OXQ; 6OXR; 6OXS; 6OXT; 6OXU; 6OXV; 6OXW; 6OXX; 6OXY; 6OXZ; 6OY0; 6OY1; 6OY2; 6OYD; 6OYR; 6PJB; 6PJC; 6PJD; 6PJE; 6PJF; 6PJG; 6PJH; 6PJI; 6PJK; 6PJL; 6PJM; 6PJN; 6PJO; 6PUT; 6PUW; 6PUY; 6PUZ; 6T6E; 6U8Q; 6UM8; 6V3K; 6VDK; 6VQS; 6VRG; 6VX2; 6W0U; 6W42; 6W6T; 7D83; 7DBM; 7DBN; 7KE0; 7L1P; 7L23; 7LDY; 7LDZ; 7LE0; 7LE1; 7LE2; 7LE3; 7LE4; 7LE5; 7LE6; 7LE7; 7LE8; 7LE9; 7LEA; 7LEB; 7LEC; 7LED; 7LEE; 7LEF; 7LEG; 7LEH; 7LEI; 7LQP; 7RQ0; 7SIA; 7T9H; 7T9O; 7U2U; 7UE1; 7UOQ; 7WBS; 7WCE; 7WCQ; 7YF6; 7ZUD; 8A1P; 8A1Q; 8BUV; 8BV2; 8CBR; 8CBS; 8CBT; 8CBU; 8CBV; 8CT5; 8CT7; 8D3S; 8F22; 8FN7; 8FND; 8FNG; 8FNH; 8FNJ; 8FNL; 8FNM; 8FNN; 8FNO; 8FNP; 8FNQ; 8TOV; 8TQP; 8WF7; 9HVP

POL_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
POL_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
POL_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
POL_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
POL_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
POL_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
POL_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
POL_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
POL_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
POL_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
POL_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)

41 entries

Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

Select_allDeselect_all
REV_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
REV_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
REV_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
REV_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
REV_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
REV_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
REV_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
REV_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
REV_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
REV_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
REV_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
REV_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
REV_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
REV_HV112
Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
REV_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
REV_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
REV_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
REV_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
REV_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
REV_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
REV_HV1C4
Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
REV_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
REV_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
REV_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
REV_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
REV_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
REV_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
REV_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
REV_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
REV_HV1S1
Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
REV_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
REV_HV1S3
Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
REV_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
REV_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
REV_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
REV_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
REV_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
REV_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
REV_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
REV_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)
REV_HV1Z6
Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)

40 entries

Protein Tat (Transactivating regulatory protein)

Select_allDeselect_all
TAT_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
TAT_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
TAT_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
TAT_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
TAT_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
TAT_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
TAT_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
TAT_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
TAT_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
TAT_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
TAT_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
TAT_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
TAT_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
TAT_HV112
Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
TAT_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
TAT_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
TAT_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
TAT_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
TAT_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
TAT_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
TAT_HV1C4
Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
TAT_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
TAT_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
TAT_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
TAT_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
TAT_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
TAT_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
TAT_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
TAT_HV1S1
Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
TAT_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
TAT_HV1S3
Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
TAT_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
TAT_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
TAT_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
TAT_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
TAT_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
TAT_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
TAT_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
TAT_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)
TAT_HV1Z6
Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)

39 entries

Virion infectivity factor (Vif) (SOR protein)

Select_allDeselect_all
VIF_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
VIF_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
VIF_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
VIF_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VIF_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VIF_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
VIF_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
VIF_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VIF_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
VIF_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VIF_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
VIF_HV1U4
Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1) reference strain
VIF_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
VIF_HV112
Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
VIF_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
VIF_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
VIF_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
VIF_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
VIF_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
VIF_HV1B5
Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
VIF_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VIF_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)

Truncated virion infectivity factor (Vif) (SOR protein)

VIF_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
VIF_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
VIF_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
VIF_HV1N5
Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
VIF_HV1NA
Human immunodeficiency virus type 1 group M subtype B (isolate N1T-A) (HIV-1)
VIF_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
VIF_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
VIF_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VIF_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
VIF_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
VIF_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
VIF_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
VIF_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
VIF_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VIF_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VIF_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)
VIF_HV1Z6
Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)

37 entries

Protein Vpr (R ORF protein) (Viral protein R)

Select_allDeselect_all
VPR_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
VPR_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
VPR_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
VPR_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VPR_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VPR_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
VPR_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
VPR_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VPR_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
VPR_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VPR_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
VPR_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
VPR_HV112
Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
VPR_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
VPR_HV196
Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) (HIV-1)
VPR_HV197
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1)
VPR_HV19N
Human immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
VPR_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
VPR_HV1B5
Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
VPR_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VPR_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
VPR_HV1M2
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
VPR_HV1MP
Human immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
VPR_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
VPR_HV1N5
Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
VPR_HV1OY
Human immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
VPR_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VPR_HV1S2
Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
VPR_HV1S3
Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
VPR_HV1S9
Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
VPR_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
VPR_HV1SE
Human immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
VPR_HV1V9
Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
VPR_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
VPR_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VPR_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VPR_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)

31 entries

Protein Vpu (U ORF protein) (Viral protein U)

Select_allDeselect_all
VPU_HV190
Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1) reference strain
VPU_HV192
Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1) reference strain
VPU_HV1A2
Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) reference strain
VPU_HV1AN
Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VPU_HV1BR
Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VPU_HV1EL
Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1) reference strain
VPU_HV1ET
Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1) reference strain
VPU_HV1H2
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VPU_HV1JR
Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1) reference strain
VPU_HV1MA
Human immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VPU_HV1MN
Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) reference strain
VPU_HV1YF
Human immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1) reference strain
VPU_HV193
Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1)
VPU_HV1B1
Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
VPU_HV1B8
Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
VPU_HV1B9
Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VPU_HV1BN
Human immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
VPU_HV1C4
Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
VPU_HV1H3
Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
VPU_HV1J3
Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
VPU_HV1LW
Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
VPU_HV1MV
Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)
VPU_HV1ND
Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
VPU_HV1RH
Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VPU_HV1S1
Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
VPU_HV1SC
Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
VPU_HV1VI
Human immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1)
VPU_HV1Y2
Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VPU_HV1YB
Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VPU_HV1Z2
Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1)
VPU_HV1Z3
Human immunodeficiency virus type 1 group M subtype U (isolate Z3) (HIV-1)