Inhibition of host IRF3 by virus

IRF3 is a key transcriptional factor involved in the signaling pathway leading to establishment of antiviral state in infected cells. Under normal conditions, IRF3 exists in a latent form in the cytoplasm. Viral infection triggers the phosphorylation of IRF3 C-terminal region. The activated IRF3 migrates to the nucleus, where it complexes with the transcription coactivator CBP/p300, leading to the transcriptional activation of the IFN-alpha and IFN-beta genes.

RIGI RIGI STING TRIM25 MAVS TRADD TRADD TRAF3 TRAF6 TRAF2 FADD RIP1 TBK1 IKKe IRF3 IRF3 IRF7 IRF7 IKb IKb DDX3 IKKgamma IKKalpha IKKbeta NFKB NFKB NFKB

Due to its crucial role in innate response, IRF3 is the target of many viral proteins. Some viral proteins interact with IRF3 and prevent its phosphorylation such as SARS coronavirus PLpro protein, while others target IRF3 for proteasome-dependent degradation, like bICP0.

Matching UniProtKB/Swiss-Prot entries

140 entries grouped by strain (browse by keywords)

3 entries

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

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E3_VACCW Protein E3 (p25)
A46_VACCW Protein A46
N2_VACCW Protein N2

2 entries

Bat coronavirus 512/2005 (BtCoV) (BtCoV/512/2005) reference strain

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R1AB_BC512 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...
R1A_BC512 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain

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NS2_BRSVA Non-structural protein 2 (NS2) (Non-structural protein 1B)
NS1_BRSVA Non-structural protein 1 (Non-structural protein 1C)

2 entries

Human coronavirus 229E (HCoV-229E) reference strain

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R1A_CVH22 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVH22 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...

2 entries

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

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ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferaseICP0) (VMW118 ...
ICP27_HHV2H mRNA export factor (Immediate-early protein IE63) (Infected cell protein 27) (ICP27) (VMW63)

2 entries

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus) reference strain

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VIRF2_HHV8P Viral IRF2-like protein (vIRF-2)

2 entries

Human respiratory syncytial virus A (strain A2) reference strain

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NS1_HRSVA Non-structural protein 1 (NS1) (Non-structural protein 1C)
NS2_HRSVA Non-structural protein 2 (NS2) (Non-structural protein 1B)

2 entries

Human respiratory syncytial virus B (strain B1) reference strain

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NS2_HRSVB Non-structural protein 2 (NS2) (Non-structural protein 1B)
NS1_HRSVB Non-structural protein 1 (Non-structural protein 1C)

2 entries

Porcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV) reference strain

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R1A_CVPPU Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_CVPPU Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...

2 entries

Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) reference strain

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R1AB_SARS2 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor ...

pdb 5R7Y; 5R7Z; 5R80; 5R81; 5R82; 5R83; 5R84; 5R8T; 5RE4; 5RE5; 5RE6; 5RE7; 5RE8; 5RE9; 5REA; 5REB; 5REC; 5RED; 5REE; 5REF; 5REG; 5REH; 5REI; 5REJ; 5REK; 5REL; 5REM; 5REN; 5REO; 5REP; 5RER; 5RES; 5RET; 5REU; 5REV; 5REW; 5REX; 5REY; 5REZ; 5RF0; 5RF1; 5RF2; 5RF3; 5RF4; 5RF5; 5RF6; 5RF7; 5RF8; 5RF9; 5RFA; 5RFB; 5RFC; 5RFD; 5RFE; 5RFF; 5RFG; 5RFH; 5RFI; 5RFJ; 5RFK; 5RFL; 5RFM; 5RFN; 5RFO; 5RFP; 5RFQ; 5RFR; 5RFS; 5RFT; 5RFU; 5RFV; 5RFW; 5RFX; 5RFY; 5RFZ; 5RG0; 5RG1; 5RG2; 5RG3; 5RGG; 5RGH; 5RGI; 5RGJ; 5RGK; 5RGL; 5RGM; 5RGN; 5RGO; 5RGP; 5RGQ; 5RGR; 5RGS; 5RGT; 5RGU; 5RGV; 5RGW; 5RGX; 5RGY; 5RGZ; 5RH0; 5RH1; 5RH2; 5RH3; 5RH4; 5RH5; 5RH6; 5RH7; 5RH8; 5RH9; 5RHA; 5RHB; 5RHC; 5RHD; 5RHE; 5RHF; 5RL6; 5RL7; 5RL8; 5RL9; 5RLB; 5RLC; 5RLD; 5RLE; 5RLF; 5RLG; 5RLH; 5RLI; 5RLJ; 5RLK; 5RLL; 5RLM; 5RLN; 5RLO; 5RLP; 5RLQ; 5RLR; 5RLS; 5RLT; 5RLU; 5RLV; 5RLW; 5RLY; 5RLZ; 5RM0; 5RM1; 5RM2; 5RM3; 5RM4; 5RM5; 5RM6; 5RM7; 5RM8; 5RM9; 5RMA; 5RMB; 5RMC; 5RMD; 5RME; 5RMF; 5RMG; 5RMH; 5RMI; 5RMJ; 5RMK; 5RML; 5RMM; 6LU7; 6LZE; 6M03; 6M0K; 6M2N; 6M2Q; 6M71; 6VWW; 6VXS; 6W01; 6W02; 6W4B; 6W4H; 6W61; 6W63; 6W6Y; 6W75; 6W9C; 6W9Q; 6WC1; 6WCF; 6WEN; 6WEY; 6WIQ; 6WJT; 6WKQ; 6WKS; 6WLC; 6WNP; 6WOJ; 6WQ3; 6WQD; 6WQF; 6WRH; 6WRZ; 6WTC; 6WTJ; 6WTK; 6WTM; 6WTT; 6WUU; 6WVN; 6WX4; 6WXC; 6WXD; 6WZU; 6X1B; 6X4I; 6XA4; 6XA9; 6XAA; 6XB0; 6XB1; 6XB2; 6XBG; 6XBH; 6XBI; 6XCH; 6XDH; 6XFN; 6XG3; 6XHM; 6XHU; 6XIP; 6XKF; 6XKH; 6XKM; 6XMK; 6XOA; 6XQS; 6XQT; 6XQU; 6XR3; 6Y2E; 6Y2F; 6Y2G; 6Y84; 6YB7; 6YNQ; 6YT8; 6YVA; 6YVF; 6YWK; 6YWL; 6YWM; 6YYT; 6YZ1; 6YZ6; 6Z2E; 6ZCT; 6ZLW; 6ZM7; 6ZME; 6ZMI; 6ZMO; 6ZMT; 6ZN5; 6ZOJ; 6ZOK; 6ZON; 6ZP4; 6ZPE; 6ZRT; 6ZRU; 6ZSL; 7AKU; 7BQ7; 7BQY; 7BRO; 7BRP; 7BTF; 7BUY; 7BV1; 7BV2; 7BZF; 7C2I; 7C2J; 7C2K; 7C2Q; 7C2Y; 7C6S; 7C6U; 7C7P; 7C8B; 7C8R; 7C8T; 7C8U; 7CBT; 7CJD; 7CJM; 7CMD; 7COM; 7CWB; 7CWC; 7CX9; 7D1M; 7D1O; 7JFQ; 7JHE; 7JIB; 7JKV; 7JME; 7JOY; 7JP1; 7JPE; 7JR3; 7JR4; 7JU7; 7JUN; 7JVZ; 7JYC; 7JYY; 7JZ0; 7K1L; 7K1O; 7K3N; 7K3T; 7K40; 7K5I; 7K6D; 7K6E; 7K7P; 7K9P; 7KAG; 7KFI; 7KFJ; 7KG3; 7KHP

R1A_SARS2 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 ...

2 entries

Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

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E3_VAR67 Protein E3
A46_VAR67 Protein A46

1 entry

Bat coronavirus 133/2005 (BtCoV) (BtCoV/133/2005) reference strain

R1A_BC133 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bat coronavirus HKU4 (BtCoV) (BtCoV/HKU4/2004) reference strain

R1A_BCHK4 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bat coronavirus HKU5 (BtCoV) (BtCoV/HKU5/2004) reference strain

R1A_BCHK5 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bat coronavirus HKU9 (BtCoV) (BtCoV/HKU9) reference strain

R1A_BCHK9 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus) reference strain

POLG_BVDVN Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); ...

1 entry

Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4) reference strain

KR2_EBVA8 Serine/threonine-protein kinase BGLF4 (EC 2.7.11.1)

1 entry

Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) reference strain

KR2_EBVB9 Serine/threonine-protein kinase BGLF4 (EC 2.7.11.1)

1 entry

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ICP0)

1 entry

Feline coronavirus (strain FIPV WSU-79/1146) (FCoV) reference strain

R1AB_FIPV Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...

1 entry

Human coronavirus OC43 (HCoV-OC43) reference strain

R1A_CVHOC Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) reference strain

PP65_HCMVA 65 kDa phosphoprotein (pp65) (65 kDa matrix phosphoprotein) (Phosphoprotein UL83) (Tegument protein ...

1 entry

Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) reference strain

PP65_HCMVM 65 kDa phosphoprotein (pp65) (65 kDa matrix phosphoprotein) (Phosphoprotein UL83) (Tegument protein ...

1 entry

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Alpha-0 protein) (Immediate-early protein IE110) ...

1 entry

Human papillomavirus type 16 reference strain

1 entry

Human papillomavirus type 18 reference strain

VE6_HPV18 Protein E6

1 entry

Human papillomavirus type 26 reference strain

VE6_HPV26 Protein E6

1 entry

Human papillomavirus type 30 reference strain

VE6_HPV30 Protein E6

1 entry

Human papillomavirus type 31 reference strain

VE6_HPV31 Protein E6

1 entry

Human papillomavirus type 33 reference strain

VE6_HPV33 Protein E6

1 entry

Human papillomavirus type 35 reference strain

VE6_HPV35 Protein E6

1 entry

Human papillomavirus type 39 reference strain

VE6_HPV39 Protein E6

1 entry

Human papillomavirus type 52 reference strain

VE6_HPV52 Protein E6

1 entry

Human papillomavirus type 58 reference strain

VE6_HPV58 Protein E6

1 entry

Human papillomavirus type 69 reference strain

VE6_HPV69 Protein E6

1 entry

Murine coronavirus (strain 2) (MHV-2) (Murine hepatitis virus) reference strain

R1A_CVM2 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Murine coronavirus (strain A59) (MHV-A59) (Murine hepatitis virus) reference strain

R1A_CVMA5 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Porcine reproductive and respiratory syndrome virus (strain Lelystad) (PRRSV) reference strain

NCAP_PRRSL Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Rotavirus A (isolate RVA/Human/United Kingdom/A64/1987/G10P11[14]) (RV-A) reference strain

NSP1_ROTH7 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)) reference strain

NSP1_ROTSH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]) (RV-A) reference strain

NSP1_ROTRH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/SA11-Both/G3P5B[2]) (RV-A) (Simian Agent 11 (strain Both)) reference strain

NSP1_ROTS1 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C) reference strain

NSP1_ROTHC Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Sendai virus (strain Z) (SeV) (Sendai virus (strain HVJ)) reference strain

V_SENDZ Protein V

1 entry

Seneca Valley virus (isolate -/United States/SSV-001/2002) (SVV) reference strain

POLG_SVV1 Genome polyprotein [Cleaved into: Leader protein; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 ...

1 entry

Severe acute respiratory syndrome coronavirus (SARS-CoV) reference strain

R1A_SARS Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Thogoto virus (isolate SiAr 126) (Tho) reference strain

ML_THOGV Protein ML (ML)

2 entries

Human coronavirus NL63 (HCoV-NL63)

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R1AB_CVHNL Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...
R1A_CVHNL Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

2 entries

Human respiratory syncytial virus A (strain Long)

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NS2_HRSVL Non-structural protein 2 (NS2) (Non-structural protein 1B)
NS1_HRSVL Non-structural protein 1 (Non-structural protein 1C)

2 entries

Human respiratory syncytial virus B (strain 18537)

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NS1_HRSV1 Non-structural protein 1 (Non-structural protein 1C)
NS2_HRSV1 Non-structural protein 2 (NS2) (Non-structural protein 1B)

2 entries

Ovine respiratory syncytial virus (strain WSU 83-1578) (ORSV)

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NS2_ORSVW Non-structural protein 2 (NS2) (Non-structural protein 1B)
NS1_ORSVW Non-structural protein 1 (Non-structural protein 1C)

2 entries

Porcine epidemic diarrhea virus (strain CV777) (PEDV)

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R1A_PEDV7 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...
R1AB_PEDV7 Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 ...

2 entries

Vaccinia virus (strain Copenhagen) (VACV)

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A46_VACCC Protein A46
E3_VACCC Protein E3 (p25)

1 entry

Bat coronavirus 279/2005 (BtCoV) (BtCoV/279/2005)

R1A_BC279 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bat coronavirus HKU3 (BtCoV) (SARS-like coronavirus HKU3)

R1A_BCHK3 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bat coronavirus Rp3/2004 (BtCoV/Rp3/2004) (SARS-like coronavirus Rp3)

R1A_BCRP3 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine coronavirus (strain 98TXSF-110-ENT) (BCoV-ENT) (BCV)

R1A_CVBEN Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine coronavirus (strain 98TXSF-110-LUN) (BCoV-LUN) (BCV)

R1A_CVBLU Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine coronavirus (strain Mebus) (BCoV) (BCV)

R1A_CVBM Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine coronavirus (strain Quebec) (BCoV) (BCV)

R1A_CVBQ Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Bovine herpesvirus 1.1 (strain Jura) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1J E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine herpesvirus 1.2 (strain K22) (BoHV-1) (Infectious bovine rhinotracheitis virus)

ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ...

1 entry

Bovine viral diarrhea virus (strain CP7) (BVDV) (Mucosal disease virus)

POLG_BVDVC Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); ...

1 entry

Bovine viral diarrhea virus (strain SD-1) (BVDV) (Mucosal disease virus)

POLG_BVDVS Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); ...

1 entry

Classical swine fever virus (strain Alfort) (CSFV) (Hog cholera virus)

POLG_CSFVA Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); ...

1 entry

Classical swine fever virus (strain Brescia) (CSFV) (Hog cholera virus)

POLG_CSFVB Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); ...

1 entry

Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)

KR2_EBVG Serine/threonine-protein kinase BGLF4 (EC 2.7.11.1)

1 entry

Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)

ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Infected cell protein 0) (RING-type E3 ubiquitin ...

1 entry

Human coronavirus HKU1 (isolate N1) (HCoV-HKU1)

R1A_CVHN1 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Human coronavirus HKU1 (isolate N2) (HCoV-HKU1)

R1A_CVHN2 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)

R1A_CVHN5 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Human papillomavirus type 34

VE6_HPV34 Protein E6

1 entry

Human papillomavirus type 45

VE6_HPV45 Protein E6

1 entry

Human papillomavirus type 51

VE6_HPV51 Protein E6

1 entry

Human papillomavirus type 68

VE6_HPV68 Protein E6

1 entry

Human papillomavirus type 70

VE6_HPV70 Protein E6

1 entry

Human respiratory syncytial virus A (strain S-2) (HRSV-S2)

NS1_HRSS2 Non-structural protein 1 (NS1) (Non-structural protein 1C)

1 entry

Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (MERS-CoV) (Betacoronavirus England 1)

R1A_MERS1 Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 ...

1 entry

Murine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus)

R1A_CVMJH Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) ...

1 entry

Rotavirus A (isolate RVA/Cat/Japan/FRV64/1989/G3P5B[3]) (RV-A)

NSP1_ROTF6 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Cow/South/Africa/Offal agent/1965/G8P6[1]) (RV-A)

NSP1_ROTAP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Cow/Thailand/A44/1988/G10P8[11]) (RV-A)

NSP1_ROTBA Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Cow/United States/B223/1983/G10P8[11]) (RV-A)

NSP1_ROTBB Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Dog/United States/K9/1981/G3P5A[3]) (RV-A)

NSP1_ROTD9 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Equine/United Kingdom/H2/1976/G3P4[12]) (RV-A) (Rotavirus A (isolate H-2))

NSP1_ROTEH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Equine/United Kingdom/L338/1988/G13P12[18]) (RV-A)

NSP1_ROTEL Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Human/Belgium/B4106/2000/G3P11[14]) (RV-A) (Rotavirus A (isolate B4106))

NSP1_ROT41 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Human/India/116E/1986/G9P8[11]) (RV-A)

NSP1_ROTHU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Human/Japan/IGV-80-3/XXXX/GXP[X]) (RV-A)

NSP1_ROTHI Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Human/United States/WI61/1983/G9P1A[8]) (RV-A)

NSP1_ROTWI Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Monkey/United States/TUCH/2003/G3P[24]) (RV-A)

NSP1_ROTTU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Mouse/Brazil/EHP/1981/G16P[20]) (RV-A)

NSP1_ROTME Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) (RV-A)

NSP1_ROTRF Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Cow/United Kingdom/UK/1975/G6P7[5]) (RV-A)

NSP1_ROTBU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Cow/United States/B641/XXXX/G6P7[5]) (RV-A)

NSP1_ROTB4 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Cow/United States/WC3/1981/G6P7[5]) (RV-A) (Rotavirus (strain Wistar calf 3))

NSP1_ROTW3 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Indonesia/69M/1980/G8P4[10]) (RV-A)

NSP1_ROTH6 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Japan/AU-1/1982/G3P3[9]) (RV-A)

NSP1_ROTH3 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Japan/K8/1977/G1P3A[9]) (RV-A)

NSP1_ROTHJ Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Japan/KU/1995/G1P1A[8]) (RV-A)

NSP1_ROTHK Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Philippines/L26/1987/G12P1B[4]) (RV-A)

NSP1_ROTHL Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/United Kingdom/ST3/1975/G4P2A[6]) (RV-A) (Rotavirus A (strain St. Thomas 3))

NSP1_ROTHT Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/United States/D/1974/G1P1A[8]) (RV-A)

NSP1_ROTAD Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/United States/DS-1/1976/G2P1B[4]) (RV-A) (Rotavirus A (strain DS1))

NSP1_ROTHD Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/United States/P/1974/G3P1A[8]) (RV-A)

NSP1_ROTHP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A)

NSP1_ROTHW Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Human/Venezuela/M37/1982/G1P2A[6]) (RV-A)

NSP1_ROTHM Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Pig/Mexico/YM/1983/G11P9[7]) (RV-A)

NSP1_ROTPY Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Pig/United States/Gottfried/1983/G4P2B[6]) (RV-A)

NSP1_ROTPG Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Pig/United States/OSU/1977/G5P9[7]) (RV-A) (Rotavirus A (strain Ohio State University))

NSP1_ROTP5 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/Rabbit/United States/ALA/XXXX/G3P11[14]) (RV-A) (Rotavirus A (strain Alabama))

NSP1_ROTRA Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/SA11-4F/G3P6[1]) (RV-A) (Simian Agent 11 (strain 4F))

NSP1_ROTS4 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/SA11-FEM/G3P6[1]) (RV-A) (Simian Agent 11 (strain FEM))

NSP1_ROTSF Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (strain RVA/SA11-Patton/G3P[X]) (RV-A) (Simian Agent 11 (strain Patton))

NSP1_ROTSP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)

NSP1_ROTPC Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Sendai virus (strain Fushimi) (SeV)

V_SENDF Protein V

1 entry

Sendai virus (strain Hamamatsu) (SeV)

V_SENDA Protein V

1 entry

Sendai virus (strain Harris) (SeV)

V_SENDH Protein V

1 entry

Sendai virus (strain Ohita) (SeV)

V_SENDO Protein V

1 entry

Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker) (SuHV-1) (Pseudorabies virus (strain Indiana-Funkhauser / Becker))

ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (Early protein 0) (EP0) (RING-type E3 ubiquitin ...

1 entry

Theiler's murine encephalomyelitis virus (strain BeAn 8386) (TMEV)

POLG_TMEVB Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...

1 entry

Theiler's murine encephalomyelitis virus (strain DA) (TMEV)

POLG_TMEVD Genome polyprotein [Cleaved into: Leader protein (L); Capsid protein VP0 (VP4-VP2); Capsid protein ...