Betatorquevirus (taxid:687332)

VIRION

image

Non-enveloped, T=1 icosahedral symmetry, with a diameter of about 30-32nm.

GENOME

Circular ssDNA genome (-) genome of about 3.8 kb.
The genome is replicated through double-stranded intermediates. It may encode for 4 proteins: ORF1 (Rep protein?), ORF2, ORF3 and ORF4.

GENE EXPRESSION

The proteins are expressed by alternative splicing of pre-mRNA.

REPLICATION

NUCLEAR

  1. Virus penetrates into the host cell.
  2. Uncoating, the viral ssDNA genome penetrates into the nucleus.
  3. The ssDNA is converted into dsDNA with the participation of cellular factors. dsDNA transcription gives rise to viral mRNAs.
  4. viral mRNAs are transcribed and translated to produce viral proteins.
  5. Replication may be mediated by a "Rep-like" protein, and would occur by rolling circle producing ssDNA genomes.
  6. These newly synthesized ssDNA can either
    a) be converted to dsDNA and serve as a template for transcription/replication
    b) be encapsidated by capsid protein and form virions released by cell lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

3 entries grouped by strain

3 entries

Torque teno mini virus 1 (isolate TLMV-CBD279) reference strain

Select_allDeselect_all
ORF3_TTVB1 Uncharacterized ORF3 protein
CAPSD_TTVB1 Capsid protein
ORF2_TTVB1 Uncharacterized ORF2 protein
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

TTV-like mini virus taxid:93678

Protein ModelArchive
Capsid protein ma-jd-viral-04594
Uncharacterized protein ma-jd-viral-55634
Uncharacterized protein ma-jd-viral-57836

Torque teno mini virus 1 (isolate TLMV-CBD279) taxid:766183

Protein ModelArchive
Capsid protein ma-jd-viral-04566
Uncharacterized ORF2 protein ma-jd-viral-57845
Uncharacterized ORF3 protein ma-jd-viral-55636

Torque teno mini virus 18 taxid:1859149

Protein ModelArchive
Capsid protein ma-jd-viral-04570
ORF2 ma-jd-viral-57842
ORF3 ma-jd-viral-34856

Torque teno mini virus 5 taxid:687373

Protein ModelArchive
Capsid protein ma-jd-viral-04591
Capsid protein ma-jd-viral-55638
Capsid protein ma-jd-viral-57844

Torque teno mini virus 6 taxid:687374

Protein ModelArchive
Capsid protein ma-jd-viral-04579
Capsid protein ma-jd-viral-55637
Capsid protein ma-jd-viral-57839

Torque teno mini virus 8 taxid:687376

Protein ModelArchive
Capsid protein ma-jd-viral-04605
ORF2 ma-jd-viral-57837

Torque teno mini virus ALA22 taxid:1535290

Protein ModelArchive
Capsid protein ma-jd-viral-04599
Capsid protein ma-jd-viral-55633
Uncharacterized protein ma-jd-viral-57841

Torque teno mini virus ALH8 taxid:1535291

Protein ModelArchive
Capsid protein ma-jd-viral-04571
Uncharacterized protein ma-jd-viral-57835