Alphairidovirinae

VIRION

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Polyhedral virions 120-350 nm in diameter. The capsid displays an icosahedral symmetry T=189-217, with an internal lipid membrane. Virions are either externally enveloped or not depending whether they budded from the cell membrane, or were arranged in paracrystaline array in the host cell cytoplasm and were released by lysis.

GENOME

Linear, dsDNA genome of about 100-170 kb. The genome contains terminal and redundant sequences and is circularly permuted.
Approximately 25% of the cytosine residues of the genome are methylated by a virus encoded DNA methyltransferase.

GENE EXPRESSION

REPLICATION

NUCLEO-CYTOPLASMIC

  1. Attachment of the viral proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the DNA core into the host cytoplasm.
  3. Viral DNA is transported to the cell nucleus where host macromolecular synthesis is rapidly shutdown. Transcription is initiated by virally modified host RNA polymerase II.
  4. Parental DNA is used to produce genome and greater than genome length DNA.
  5. Progeny DNA is transported into cytoplasmic viral factories where large concatamers of viral DNA are formed by recombination. Transcription of very late transcripts may also take place in the cytoplasm.
  6. Assembly of new virions in the cytoplasm.
  7. Virions exit the cell by budding or cell lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

102 entries grouped by strain (browse by keywords)

98 entries

Frog virus 3 (isolate Goorha) (FV-3) reference strain

Select_allDeselect_all
VINT_FRG3G Integrase homolog
DNMT_FRG3G Probable DNA (cytosine-5)-methyltransferase (EC 2.1.1.37) (Orphan methyltransferase M.Fvi3IP) ...
RIR2_FRG3G Putative ribonucleoside-diphosphate reductase small subunit 067L (EC 1.17.4.1)
RPB2_FRG3G Putative DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)
RIR1_FRG3G Putative ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase ...
019R_FRG3G Putative serine/threonine-protein kinase 019R (EC 2.7.11.1)
RPB1_FRG3G Putative DNA-directed RNA polymerase 008R (EC 2.7.7.6)
MCP_FRG3G Major capsid protein (MCP) (P50)
095R_FRG3G Putative RAD2-like endonuclease 095R (EC 3.1.-.-)
088R_FRG3G Putative FAD-linked sulfhydryl oxidase 088R (EC 1.8.3.2)
RNC_FRG3G Putative ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)
075L_FRG3G Uncharacterized protein 075L
DUT_FRG3G Putative deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23)
DPOL_FRG3G Putative DNA polymerase 060R (EC 2.7.7.7)
055L_FRG3G Putative helicase 055L (EC 3.6.4.-)
053R_FRG3G Putative myristoylated protein 053R
O22R_FRG3G Putative helicase 022R (EC 3.6.4.-)
009L_FRG3G Putative helicase 009L (EC 3.6.4.-)
ICP18_FRG3G Immediate-early protein ICP-18
ICP46_FRG3G Immediate-early protein ICP-46
VP31_FRG3G Early 31 kDa protein (P31K)
055R_FRG3G Uncharacterized protein 055R
098R_FRG3G Uncharacterized protein 098R
097R_FRG3G Uncharacterized protein 097R
096R_FRG3G Uncharacterized protein 096R
094L_FRG3G Uncharacterized protein 094L
093L_FRG3G Uncharacterized protein 093L
092R_FRG3G Uncharacterized protein 092R
089R_FRG3G Uncharacterized protein 89R
087L_FRG3G Uncharacterized protein 087L
044R_FRG3G Uncharacterized protein 044R
DNK_FRG3G Putative deoxynucleoside kinase (EC 2.7.1.-)
084R_FRG3G Uncharacterized protein 084R
081R_FRG3G Putative transcription elongation factor S-II-like protein 81R
079R_FRG3G Uncharacterized protein 079R
078L_FRG3G Uncharacterized protein 078L
077L_FRG3G LCDV1 orf2-like protein
076R_FRG3G Uncharacterized protein 076R
074L_FRG3G Uncharacterized protein 074L
073L_FRG3G Uncharacterized protein 073L
072L_FRG3G Uncharacterized protein 072L
071R_FRG3G Uncharacterized protein 071R
070R_FRG3G Uncharacterized protein 070R
069R_FRG3G Transmembrane protein 069R
068R_FRG3G Putative uncharacterized protein 068R
066L_FRG3G Uncharacterized protein 066L
065L_FRG3G Putative collagen-like domain-containing protein 065L
064R_FRG3G Caspase recruitment domain-containing protein 064R
061L_FRG3G Uncharacterized protein 061L
059L_FRG3G Uncharacterized protein 059L
058R_FRG3G Uncharacterized protein 058R
057R_FRG3G Putative phosphotransferase 057R
056R_FRG3G Uncharacterized protein 056R
054L_FRG3G Uncharacterized protein 054L
052L_FRG3G Uncharacterized protein 052L
051R_FRG3G Uncharacterized protein 051R
050L_FRG3G Uncharacterized protein 050L
049L_FRG3G Putative SAP domain-containing protein 049L
048L_FRG3G Uncharacterized protein 048L
047L_FRG3G Uncharacterized protein 047L
046L_FRG3G Uncharacterized protein 046L
045L_FRG3G Uncharacterized protein 045L
086L_FRG3G Uncharacterized protein 086L
043R_FRG3G Uncharacterized protein 043R
042L_FRG3G Uncharacterized protein 042L
041R_FRG3G Uncharacterized protein 041R
040R_FRG3G Uncharacterized protein 040R
039R_FRG3G Uncharacterized protein 039R
037R_FRG3G uncharacterized protein 037R
036L_FRG3G Uncharacterized protein 036L
035L_FRG3G Uncharacterized protein 035L
034R_FRG3G Uncharacterized protein 034R
033R_FRG3G Transmembrane protein 033R
032R_FRG3G Uncharacterized protein 032R
031R_FRG3G Uncharacterized protein 031R
030R_FRG3G Uncharacterized protein 030R
029L_FRG3G Uncharacterized protein 029L
028R_FRG3G Uncharacterized protein 028R
027R_FRG3G Uncharacterized protein 027R
024R_FRG3G Uncharacterized protein 024R
023R_FRG3G Uncharacterized protein 023R
021L_FRG3G Uncharacterized protein 021L
020R_FRG3G Uncharacterized protein 020R
018L_FRG3G Uncharacterized protein 018L
017L_FRG3G Uncharacterized protein 017L
015R_FRG3G Uncharacterized protein 015R
014R_FRG3G Uncharacterized protein 014R
013R_FRG3G Uncharacterized protein 013R
012L_FRG3G Uncharacterized protein 012L
011R_FRG3G Uncharacterized protein 011R
010R_FRG3G Uncharacterized protein 010R
007R_FRG3G Uncharacterized protein 007R
006R_FRG3G Uncharacterized protein 006R
005R_FRG3G Uncharacterized protein 005R
004R_FRG3G Uncharacterized protein 004R
003R_FRG3G Uncharacterized protein 3R
002L_FRG3G Uncharacterized protein 002L
001R_FRG3G Putative transcription factor 001R

1 entry

Lymphocystis disease virus 1 (isolate Darai) (LCDV-1) reference strain

MCP_LCDV1 Major capsid protein (MCP) (P50)

2 entries

Red sea bream iridovirus (RSIV)

Select_allDeselect_all
RIR2_RSIV Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small ...
DPOL_RSIV DNA polymerase (EC 2.7.7.7)

1 entry

Rana tigrina ranavirus

MCP_RTRV Major capsid protein (MCP) (P50)